Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles

Authors: Livio Racané, Valentina Rep, Sandra Kraljević Pavelić, Petra Grbčić, Iva Zonjić, Marijana Radić Stojković, Martin C. Taylor, John M. Kelly, Silvana Raić-Malić

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1952-1967 (2021)

Subject Terms: benzothiazole, amidine, antiproliferative activity, trypanosoma brucei, ctdna binding, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/9f312d475f254be3942d3245001a5743

Znanstveno-istraživačka djelatnost Zavoda za organsku kemiju u razdoblju 2009. – 2019.

Authors: Tatjana Gazivoda Kraljević, Marijana Hranjec, Silvana Raić-Malić, Irena Škorić, Dragana Vuk

Source: Kemija u Industriji, Vol 68, Iss 9-10, Pp 497-506 (2019)

Subject Terms: Zavod za organsku kemiju, sintetska organska kemija, medicinska kemija, organska fotokemija, Chemistry, QD1-999

File Description: electronic resource

Relation: http://silverstripe.fkit.hr/kui/assets/Uploads/14-497-506.pdf; https://doaj.org/toc/0022-9830; https://doaj.org/toc/1334-9090

Access URL: https://doaj.org/article/4383cecaab564d33a0f4314173bbf7c0

Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA

Authors: Andrea Bistrović, Luka Krstulović, Ivana Stolić, Domagoj Drenjančević, Jasminka Talapko, Martin C. Taylor, John M. Kelly, Miroslav Bajić, Silvana Raić-Malić

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1323-1334 (2018)

Subject Terms: Benzimidazole, 1,2,3-triazole, resistant bacteria, antiprotozoal activity, Trypanosoma brucei, MRSA, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/e0697d37ff024c3b90f523c1633faed8

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549

Authors: Andrea Bistrović, Petra Grbčić, Anja Harej, Mirela Sedić, Sandra Kraljević-Pavelić, Sanja Koštrun, Janez Plavec, Damjan Makuc, Silvana Raić-Malić

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 271-285 (2018)

Subject Terms: Purine, 1,2,3-triazole, purinomimetic, non-small cell lung cancer A549, p38 MAPK, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/c844140eb5fe4e668b2ce166f827fdc5

Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding

Authors: Silvija Maračić, Petra Grbčić, Suresh Shammugam, Marijana Radić Stojković, Krešimir Pavelić, Mirela Sedić, Sandra Kraljević Pavelić, Silvana Raić-Malić

Source: Molecules, Vol 26, Iss 22, p 7060 (2021)

Subject Terms: amidine, amidoxime, antiproliferative activity, DNA binding, fluorescence, CD spectroscopy, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/22/7060; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/8cb32eaeb4324ad7a8d052bd4effcb96

Solvent-free copper-catalyzed click chemistry for the synthesis of N-heterocyclic hybrids based on quinoline and 1,2,3-triazole

Authors: Martina Tireli, Silvija Maračić, Stipe Lukin, Marina Juribašić Kulcsár, Dijana Žilić, Mario Cetina, Ivan Halasz, Silvana Raić-Malić, Krunoslav Užarević

Source: Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2352-2363 (2017)

Subject Terms: electron spin resonance (ESR) spectroscopy, in situ Raman monitoring, mechanochemistry, quinoline, solid-state click chemistry, Science, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://doaj.org/toc/1860-5397

Access URL: https://doaj.org/article/532d798ec62246a6bbb4e792cccb7ac8

Novel Bis- and Mono-Pyrrolo[2,3-d]pyrimidine and Purine Derivatives: Synthesis, Computational Analysis and Antiproliferative Evaluation

Authors: Andrea Bistrović Popov, Robert Vianelo, Petra Grbčić, Mirela Sedić, Sandra Kraljević Pavelić, Krešimir Pavelić, Silvana Raić-Malić

Source: Molecules, Vol 26, Iss 11, p 3334 (2021)

Subject Terms: pyrrolo[2,3-d]pyrimidines, purine, DFT calculations, ultrasound, antiproliferative activity, pancreatic adenocarcinoma, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/11/3334; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/befb393670054d2cbc6c8a3199017e8c

Purine and Purine Isostere Derivatives of Ferrocene: An Evaluation of ADME, Antitumor and Electrochemical Properties

Authors: Valentina Rep, Martina Piškor, Helena Šimek, Petra Mišetić, Petra Grbčić, Jasna Padovan, Vesna Gabelica Marković, Dijana Jadreško, Krešimir Pavelić, Sandra Kraljević Pavelić, Silvana Raić-Malić

Source: Molecules, Vol 25, Iss 7, p 1570 (2020)

Subject Terms: purine, ferrocene, cytostatic activity, permeability, microsomal stability, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/7/1570; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/96d347efcb4c4b9fa825f7fe5dde4368

Therapeutic Perspective of Vitamin C and Its Derivatives

Authors: Andrijana Meščić Macan, Tatjana Gazivoda Kraljević, Silvana Raić-Malić

Source: Antioxidants, Vol 8, Iss 8, p 247 (2019)

Subject Terms: l-ascorbic acid, vitamin C, butenolide, antitumor, anticancer, antiviral, antioxidant, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/8/8/247; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/8adb64051bd84573a91838953d903c3f

Synthesis and Biological Evaluation of a New Acyclic Pyrimidine Derivative as a Probe for Imaging Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression

Authors: Simon M. Ametamey, Silvana Raić-Malić, Stjepko Čermak, Roger Slavik, Adrienne Müller, Thomas Betzel, Andrijana Meščić

Source: Molecules, Vol 18, Iss 7, Pp 8535-8549 (2013)

Subject Terms: acyclic pyrimidine nucleoside analogues, PCV-like side chain, fluorination, radiosynthesis, positron emission tomography (PET), HSV1-TK, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/18/7/8535; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/111491df8bfe4cd79141878d67e2890f

C-5 Hydroxyethyl and Hydroxypropyl Acyclonucleosides as Substrates for Thymidine Kinase of Herpes Simplex Virus Type 1 (HSV-1 TK): Syntheses and Biological Evaluation

Authors: Silvana Raić-Malić, Simon M. Ametamey, Leonardo Scapozza, Davorka Završnik, Ursina Müller, Amar Osmanović, Ivana Novaković, Svjetlana Krištafor, Andrijana Meščić

Source: Molecules, Vol 18, Iss 5, Pp 5104-5124 (2013)

Subject Terms: acyclic nucleoside analogues, 5-substituted pyrimidines, herpes simplex virus type 1 thymidine kinase (HSV-1 TK), positron emission tomography (PET), Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/18/5/5104; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/7e6d1abd87ac407bb52c113da0322b20

Methoxymethyl (MOM) Group Nitrogen Protection of Pyrimidines Bearing C-6 Acyclic Side-Chains

Authors: Janez Plavec, Tobias L. Ross, Simon M. Ametamey, Silvana Raić-Malić, Damjan Makuc, Martina Petrović, Svjetlana Krištafor, Tatjana Gazivoda Kraljević

Source: Molecules, Vol 16, Iss 6, Pp 5113-5129 (2011)

Subject Terms: N-methoxymethyl protecting group, C-6 isobutyl pyrimidine derivatives, N-1 and N-3 regioisomers, NOE experiments, positron emission tomography (PET), Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/16/6/5113/; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/c53cc0a05b4d4a2481d2e52523c339c8

Synthesis, Structural Studies and Antitumoral Evaluation of C-6 Alkyl and Alkenyl Side Chain Pyrimidine Derivatives S

Authors: Marijeta Kralj, Silvana Raić-Malić, Janez Plavec, Lidija Šuman, Damjan Makuc, Svjetlana Krištafor, Tatjana Gazivoda Kraljević

Source: Molecules, Vol 14, Iss 12, Pp 4866-4879 (2009)

Subject Terms: C-6 alkyl and alkenyl pyrimidine derivatives, NMR conformational analysis, cytostatic activity evaluations, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/14/12/4866/; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/fc8d071b26a740548e1e9fda697389df

Synthesis and structural studies of C-5 aryl- and C-6 alkyl-substituted pyrimidine derivatives.

Authors: Tatjana Gazivoda, Svjetlana Krištafor, Mario Cetina, Ante Nagl, Silvana Raić-Malić

Source: Structural Chemistry; Jun2008, Vol. 19 Issue 3, p441-449, 9p

Subject Terms: MOLECULES, STEREOCHEMISTRY, CHEMICAL structure, PHYSICAL & theoretical chemistry

Hydantoin Derivatives of L- and D-amino acids: Synthesis and Evaluation of Their Antiviral and Antitumoral Activity

Authors: Mladen Mintas, Erik De Clercq, Jan Balzarini, Krešimir Pavelic, Marijeta Kralj, Katja Ester, Silvana Raic-Malic, Branka Zorc, Zrinka Rajic

Source: Molecules, Vol 11, Iss 11, Pp 837-848 (2006)

Subject Terms: Hydantoin, L- and D-amino acids, antiviral activity, antitumoral activity., Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/11/11/837/; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/a9f17c77df8643d7a41d6e9159bdae86