Long-term efficacy and safety of continued complement C1s inhibition with sutimlimab in cold agglutinin disease: CADENZA study Part BResearch in context

Authors: Alexander Röth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D’Sa, Bernd Jilma, Marc Michel, Ilene C. Weitz, Masaki Yamaguchi, Jun-ichi Nishimura, Josephine M.I. Vos, Joan Cid, Michael Storek, Nancy Wong, Ronnie Yoo, Deepthi Jayawardene, Shruti Srivastava, Marek Wardęcki, Frank Shafer, Michelle Lee, Catherine M. Broome

Source: EClinicalMedicine, Vol 74, Iss , Pp 102733- (2024)

Subject Terms: Autoimmune haemolytic anaemia, Cold agglutinin disease, Classical complement pathway, Complement C1s, Sutimlimab, Haemolysis, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537024003122; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/3d87b23487004a108e8a911cd7c2cb67

Time for newer approach in age-old AIHA: Daratumumab?

Authors: Sigbjørn Berentsen, Suvro Sankha Datta

Source: The Lancet Regional Health - Southeast Asia, Vol 25, Iss , Pp 100410- (2024)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S277236822400060X; https://doaj.org/toc/2772-3682

Access URL: https://doaj.org/article/305b86938001496cbcdcc4d845d26e0e

P1471: SUSTAINED EFFICACY OF SUTIMLIMAB, A COMPLEMENT C1S INHIBITOR, IN PATIENTS WITH COLD AGGLUTININ DISEASE: RESULTS FROM PART B OF THE PHASE 3 CADENZA STUDY

Authors: Alexander Röth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D’sa, Bernd Jilma, Marc Michel, Ilene C Weitz, Masaki Yamaguchi, Jun-Ichi Nishimura, Josephine Vos, Joan Cid, Michael Storek, Nancy Wong, Ronnie Yoo, Deepthi Jayawardene, Shruti Srivastava, Marek Wardęcki, Frank Shafer, Michelle Lee, Catherine M Broome

Source: HemaSphere, Vol 7, p e83270db (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000972768.83270.db; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/34c6141f83354a40a8c76a7bba4fdcb6

P1469: INHIBITION OF COMPLEMENT C1S WITH SUTIMLIMAB IN PATIENTS WITH COLD AGGLUTININ DISEASE (CAD): RESULTS FOLLOWING 9-WEEK OFF-TREATMENT PERIOD (WASHOUT) IN THE PHASE 3 CADENZA STUDY

Authors: Alexander Röth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D’sa, Bernd Jilma, Marc Michel, Ilene C Weitz, Masaki Yamaguchi, Jun-Ichi Nishimura, Josephine Vos, Joan Cid, Michael Storek, Nancy Wong, Ronnie Yoo, Deepthi Jayawardene, Katarina Kralova, Marek Wardęcki, Frank Shafer, Michelle Lee, Catherine M Broome

Source: HemaSphere, Vol 7, p e3331235 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000972760.33312.35; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/bec69a5d1b2b4ad8afba22ee30dce3db

Cold Agglutinin Disease: Improved Understanding of Pathogenesis Helps Define Targets for Therapy

Authors: Sigbjørn Berentsen, Shirley D’Sa, Ulla Randen, Agnieszka Małecka, Josephine M. I. Vos

Source: Hemato, Vol 3, Iss 4, Pp 574-594 (2022)

Subject Terms: cold agglutinin disease, autoimmune hemolytic anemia, lymphoproliferative, monoclonal gammopathy, Waldenström’s macroglobulinemia, complement, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2673-6357/3/4/40; https://doaj.org/toc/2673-6357

Access URL: https://doaj.org/article/5cd89b739fbe4aef947c9a3f6fbd6fa5

Sutimlimab for the Treatment of Cold Agglutinin Disease

Authors: Sigbjørn Berentsen

Source: HemaSphere, Vol 7, Iss 5, p e879 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000879; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/b169b3a60a5d4c46869092945120877d

The choice of new treatments in autoimmune hemolytic anemia: how to pick from the basket?

Authors: Sigbjørn Berentsen, Bruno Fattizzo, Wilma Barcellini

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: clinical trials, complement inhibitors, cold agglutinin disease, corticosteroids, immune suppression, rituximab, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1180509/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/c68af42595fa4d3e9c8edb0bd07b822e

Paroxysmal cold hemoglobinuria successfully treated with complement inhibition

Authors: Sarah A. Lau-Braunhut, Hannah Stone, Griffin Collins, Sigbjørn Berentsen, Benjamin S. Braun, Matt S. Zinter

Source: Blood Advances, Vol 3, Iss 22, Pp 3575-3578 (2019)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952920317560; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/a63a1657bcf1481e81261c9d57936342

Occurrence, thromboembolic risk, and mortality in Danish patients with cold agglutinin disease

Authors: Lauren C. Bylsma, Anne Gulbech Ording, Adam Rosenthal, Buket Öztürk, Jon P. Fryzek, Jaime Morales Arias, Alexander Röth, Sigbjørn Berentsen

Source: Blood Advances, Vol 3, Iss 20, Pp 2980-2985 (2019)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952920318164; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/16137741f18f4030a009c7a79fde986c

New Insights in the Pathogenesis and Therapy of Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia

Authors: Sigbjørn Berentsen

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: autoimmune hemolytic anemia, cold agglutinin disease, lymphoproliferative, complement, inflammation, therapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00590/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/63f9b76ea73d4e67bd6cb8714ac2cfa0

Novel insights into the treatment of complement-mediated hemolytic anemias

Authors: Sigbjørn Berentsen, Anita Hill, Quentin A. Hill, Tor Henrik Anderson Tvedt, Marc Michel

Source: Therapeutic Advances in Hematology, Vol 10 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2040-6215

Access URL: https://doaj.org/article/1273279ea0664bc8b879f3a23b95089b

Development of Multiple Myeloma of the IgA Type in a Patient with Cold Agglutinin Disease: Transformation or Coincidence?

Authors: Øystein Sefland, Ulla Randen, Sigbjørn Berentsen

Source: Case Reports in Hematology, Vol 2019 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2090-6560; https://doaj.org/toc/2090-6579

Access URL: https://doaj.org/article/33a595ccb2394508863747f7c082f62f

Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity

Authors: Agnieszka Małecka, Gunhild Trøen, Anne Tierens, Ingunn Østlie, Jędrzej Małecki, Ulla Randen, Sigbjørn Berentsen, Geir E. Tjønnfjord, Jan M.A. Delabie

Source: Haematologica, Vol 101, Iss 9 (2016)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7829; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/7880d0a3a51a44d9ac0cd51128cd550d

Primary cold agglutinin-associated lymphoproliferative disease: a B-cell lymphoma of the bone marrow distinct from lymphoplasmacytic lymphoma

Authors: Ulla Randen, Gunhild Trøen, Anne Tierens, Chloé Steen, Abdirashid Warsame, Klaus Beiske, Geir E. Tjønnfjord, Sigbjørn Berentsen, Jan Delabie

Source: Haematologica, Vol 99, Iss 3 (2014)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/6966; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/cf99e75ed8d6484283e3a4fcd9f853d9

Fast Facts: Cold Agglutinin Disease

Authors: Wilma Barcellini, Catherine M. Broome, Sigbjørn Berentsen

Resource Type: eBook.

Categories: MEDICAL / Hematology

Rituximab for the treatment of autoimmune cytopenias

Authors: Sigbjørn Berentsen

Source: Haematologica, Vol 92, Iss 12 (2007)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/4657; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/6d8777f7fc7c4af29130233aae490826

Editorial: Practical recommendations and consensus for the management of immune mediated hematologic diseases

Authors: Bruno Fattizzo, Sigbjorn Berentsen, Wilma Barcellini

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: paroxysmal nocturnal hemoglobinuria, warm autoimmune hemolytic anemia, cold agglutinin disease, immune thrombocytopenia, target therapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1364227/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9c1829eac4dc493f89f0c9fa3a96a3ac

Complement C1s inhibition with sutimlimab results in durable response in cold agglutinin disease: CARDINAL study 1-year interim follow-up results

Authors: Alexander Roth, Wilma Barcellini, Shirley D’Sa, Yoshitaka Miyakawa, Catherine M. Broome, Marc Michel, David J. Kuter, Bernd Jilma, Tor Henrik Anderson Tvedt, Ilene C. Weitz, Parija Patel, Xiaoyu Jiang, Caroline Reuter, Jun Su, Frank Shafer, Michelle Lee, Sigbjorn Berentsen

Source: Haematologica, Vol 107, Iss 7 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10538; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/ea05723d0a0f40ebb76ce93393407b84

Primary Cold Agglutinin Associated Lymphoproliferative Disease: A B-Cell Lymphoma Of The Bone Marrow Distinct From Lymphoplasmacytic Lymphoma

Authors: Randen, Ulla ^*, Trøen, Gunhild ^*, Tierens, Anne Maria, Steen, Chloe ^*, Abdirashid, Warsame ^*, Klaus, Beiske ^*, Geir, Tjønnfjord ^*, Sigbjørn, Berentsen ^*, Delabie, Jan ^*

Source: In Blood 15 November 2013 122(21):4335-4335