CABA-V7: a prospective biomarker selected trial of cabazitaxel treatment in AR-V7 positive prostate cancer patients

Authors: Isebia, Khrystany T., Mostert, Bianca, Belderbos, Bodine P.S., Buck, Stefan A.J., Helmijr, Jean C.A., Kraan, Jaco, Beaufort, Corine M., Van, Mai N., Oomen - de Hoop, Esther, Sieuwerts, Anieta M., van IJcken, Wilfred F.J., van den Hout - van Vroonhoven, Mirjam C.G.N., Brouwer, Rutger W.W., Oole, Edwin, Hamberg, Paul, Haberkorn, Brigitte C.M., Helgason, Helgi H., de Wit, Ronald, Sleijfer, Stefan, Mathijssen, Ron H.J., Martens, John W.M., Jansen, Maurice P.H.M., van Riet, Job, Lolkema, Martijn P.

Source: In European Journal of Cancer December 2022 177:33-44

A pipeline for copy number profiling of single circulating tumour cells to assess intrapatient tumour heterogeneity

Authors: Deger, Teoman, Mendelaar, Pauline A. J., Kraan, Jaco, Prager‐van der Smissen, Wendy J. C., Vlugt‐Daane, Michelle, Bindels, Eric M. J., Sieuwerts, Anieta M., Sleijfer, Stefan, Wilting, Saskia M., Hollestelle, Antoinette, Martens, John W. M.

Source: Molecular oncology. 16(16):2981-3000

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158343697.0x000001&indx=1&recIds=ETOCvdc_100158343697.0x000001

Generating human prostate cancer organoids from leukapheresis enriched circulating tumour cells

Authors: Mout, Lisanne, van Dessel, Lisanne F., Kraan, Jaco, de Jong, Anouk C., Neves, Rui P.L., Erkens-Schulze, Sigrun, Beaufort, Corine M., Sieuwerts, Anieta M., van Riet, Job, Woo, Thomas L.C., de Wit, Ronald, Sleijfer, Stefan, Hamberg, Paul, Sandberg, Yorick, te Boekhorst, Peter A.W., van de Werken, Harmen J.G., Martens, John W.M., Stoecklein, Nikolas H., van Weerden, Wytske M., Lolkema, Martijn P.

Source: In European Journal of Cancer June 2021 150:179-189

Associations between AR-V7 status in circulating tumour cells, circulating tumour cell count and survival in men with metastatic castration-resistant prostate cancer

Authors: Belderbos, Bodine P.S., Sieuwerts, Anieta M., Hoop, Esther Oomen-de, Mostert, Bianca, Kraan, Jaco, Hamberg, Paul, Van, Mai N., Beaufort, Corine M., Onstenk, Wendy, van Soest, Robert J., Martens, John, Sleijfer, Stefan, de Wit, Ronald, Mathijssen, Ron H.J., Lolkema, Martijn P.

Source: In European Journal of Cancer November 2019 121:48-54

Generation of in situ sequencing based OncoMaps to spatially resolve gene expression profiles of diagnostic and prognostic markers in breast cancer

Authors: Svedlund, Jessica, Strell, Carina, Qian, Xiaoyan, Zilkens, Kilian J.C., Tobin, Nicholas P., Bergh, Jonas, Sieuwerts, Anieta M., Nilsson, Mats

Source: In EBioMedicine October 2019 48:212-223

Proteome-wide onco-proteogenomic somatic variant identification in ER-positive breast cancer

Authors: Dimitrakopoulos, Lampros, Prassas, Ioannis, Sieuwerts, Anieta M., Diamandis, Eleftherios P., Martens, John W.M., Charames, George S.

Source: In Clinical Biochemistry April 2019 66:63-75

An Optimized Workflow to Evaluate Estrogen Receptor Gene Mutations in Small Amounts of Cell-Free DNA

Authors: Vitale, Silvia R., Sieuwerts, Anieta M., Beije, Nick, Kraan, Jaco, Angus, Lindsay, Mostert, Bianca, Reijm, Esther A., Van, Ngoc M., van Marion, Ronald, Dirix, Luc Y., Hamberg, Paul, de Jongh, Felix E., Jager, Agnes, Foekens, John A., Vigneri, Paolo, Sleijfer, Stefan, Jansen, Maurice P.H.M., Martens, John W.M.

Source: In The Journal of Molecular Diagnostics January 2019 21(1):123-137

An In-Depth Evaluation of the Validity and Logistics Surrounding the Testing of AR-V7 mRNA Expression in Circulating Tumor Cells

Authors: Sieuwerts, Anieta M., Mostert, Bianca, van der Vlugt-Daane, Michelle, Kraan, Jaco, Beaufort, Corine M., Van, Mai, Prager, Wendy J.C., De Laere, Bram, Beije, Nick, Hamberg, Paul, Westgeest, Hans M., Tascilar, Metin, Dirix, Luc Y., Onstenk, Wendy, de Wit, Ronald, Lolkema, Martijn P., Mathijssen, Ron H.J., Martens, John W.M., Sleijfer, Stefan

Source: In The Journal of Molecular Diagnostics May 2018 20(3):316-325

AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel

Authors: Sieuwerts, Anieta M., Onstenk, Wendy, Kraan, Jaco, Beaufort, Corine M., Van, Mai, De Laere, Bram, Dirix, Luc Y., Hamberg, Paul, Beeker, Aart, Meulenbeld, Hielke J., Creemers, Geert‐Jan, Weerden, Wytske M., Jenster, Guido W., Nieuweboer, Annemieke J. M., Mathijssen, Ron H. J., Wit, Ronald, Martens, John W. M., Sleijfer, Stefan

Source: Molecular oncology. 13(8):1795-1807

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087939212.0x000001&indx=1&recIds=ETOCvdc_100087939212.0x000001

Genomic Evolution of Breast Cancer Metastasis and Relapse

Authors: Yates, Lucy R., Knappskog, Stian, Wedge, David, Farmery, James H.R., Gonzalez, Santiago, Martincorena, Inigo, Alexandrov, Ludmil B., Van Loo, Peter, Haugland, Hans Kristian, Lilleng, Peer Kaare, Gundem, Gunes, Gerstung, Moritz, Pappaemmanuil, Elli, Gazinska, Patrycja, Bhosle, Shriram G., Jones, David, Raine, Keiran, Mudie, Laura, Latimer, Calli, Sawyer, Elinor, Desmedt, Christine, Sotiriou, Christos, Stratton, Michael R., Sieuwerts, Anieta M., Lynch, Andy G., Martens, John W., Richardson, Andrea L., Tutt, Andrew, Lønning, Per Eystein, Campbell, Peter J.

Source: In Cancer Cell 14 August 2017 32(2):169-184

Gene Expression Differences between Ductal Carcinoma in Situ with and without Progression to Invasive Breast Cancer

Authors: Doebar, Shusma C., Sieuwerts, Anieta M., de Weerd, Vanja, Stoop, Hans, Martens, John W.M., van Deurzen, Carolien H.M.

Source: In The American Journal of Pathology July 2017 187(7):1648-1655

T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression

Authors: Mustafa, Dana A. M., Pedrosa, Rute M. S. M., Smid, Marcel, van der Weiden, Marcel, de Weerd, Vanja, Nigg, Alex L., Berrevoets, Cor, Zeneyedpour, Lona, Priego, Neibla, Valiente, Manuel, Luider, Theo M., Debets, Reno, Martens, John W. M., Foekens, John A., Sieuwerts, Anieta M., Kros, Johan M.

Source: Acta neuropathologica. 135(4):581-599

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141526181.0x000001&indx=1&recIds=ETOCvdc_100141526181.0x000001

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

Authors: Beije, Nick, Onstenk, Wendy, Kraan, Jaco, Sieuwerts, Anieta M., Hamberg, Paul, Dirix, Luc Y., Brouwer, Anja, de Jongh, Felix E., Jager, Agnes, Seynaeve, Caroline M., Van, Ngoc M., Foekens, John A., Martens, John W.M., Sleijfer, Stefan

Source: In Neoplasia November 2016 18(11):647-653

GATA3 mRNA expression, but not mutation, associates with longer progression-free survival in ER-positive breast cancer patients treated with first-line tamoxifen for recurrent disease

Authors: Liu, Jingjing, Prager–van der Smissen, Wendy J.C., Look, Maxime P., Sieuwerts, Anieta M., Smid, Marcel, Meijer–van Gelder, Marion E., Foekens, John A., Hollestelle, Antoinette, Martens, John W.M. ^*

Source: In Cancer Letters 28 June 2016 376(1):104-109

Gene expression profiles of circulating tumor cells versus primary tumors in metastatic breast cancer

Authors: Onstenk, Wendy ^*, Sieuwerts, Anieta M., Weekhout, Marleen, Mostert, Bianca, Reijm, Esther A., van Deurzen, Carolien H.M., Bolt-de Vries, Joan B., Peeters, Dieter J., Hamberg, Paul, Seynaeve, Caroline, Jager, Agnes, de Jongh, Felix E., Smid, Marcel, Dirix, Luc Y., Kehrer, Diederik F.S., van Galen, Anne, Ramirez-Moreno, Raquel, Kraan, Jaco, Van, Mai, Gratama, Jan W., Martens, John W.M., Foekens, John A., Sleijfer, Stefan

Source: In Cancer Letters 28 June 2015 362(1):36-44

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease

Authors: Jansen, Maurice P.H.M., Sas, Leen, Sieuwerts, Anieta M., Van Cauwenberghe, Caroline, Ramirez-Ardila, Diana, Look, Maxime, Ruigrok-Ritstier, Kirsten, Finetti, Pascal, Bertucci, François, Timmermans, Mieke M., van Deurzen, Carolien H.M., Martens, John W.M., Simon, Iris, Roepman, Paul, Linn, Sabine C., van Dam, Peter, Kok, Marleen, Lardon, Filip, Vermeulen, Peter B., Foekens, John A., Dirix, Luc, Berns, Els M.J.J., Van Laere, Steven

Source: In Molecular Oncology June 2015 9(6):1218-1233

Proper genomic profiling of (BRCA1-mutated) basal-like breast carcinomas requires prior removal of tumor infiltrating lymphocytes

Authors: Massink, Maarten P.G., Kooi, Irsan E., van Mil, Saskia E., Jordanova, Ekaterina S., Ameziane, Najim, Dorsman, Josephine C., van Beek, Daphne M., van der Voorn, J. Patrick, Sie, Daoud, Ylstra, Bauke, van Deurzen, Carolien H.M., Martens, John W., Smid, Marcel, Sieuwerts, Anieta M., de Weerd, Vanja, Foekens, John A., van den Ouweland, Ans M.W., van Dyk, Ewald, Nederlof, Petra M., Waisfisz, Quinten, Meijers-Heijboer, Hanne

Source: In Molecular Oncology April 2015 9(4):877-888

mRNA expression profiles in circulating tumor cells of metastatic colorectal cancer patients

Authors: Mostert, Bianca, Sieuwerts, Anieta M., Bolt-de Vries, Joan, Kraan, Jaco, Lalmahomed, Zarina, van Galen, Anne, van der Spoel, Petra, de Weerd, Vanja, Ramírez-Moreno, Raquel, Smid, Marcel, Verhoef, Cornelis, IJzermans, Jan N.M., Gratama, Jan W., Sleijfer, Stefan, Foekens, John A., Martens, John W.M.

Source: In Molecular Oncology April 2015 9(4):920-932

Circulating tumour cells and lung microvascular tumour cell retention in patients with metastatic breast and cervical cancer

Authors: Peeters, Dieter J.E. ^*, Brouwer, Anja, Van den Eynden, Gert G., Rutten, Annemie, Onstenk, Wendy, Sieuwerts, Anieta M., Van Laere, Steven J., Huget, Philippe, Pauwels, Patrick, Peeters, Marc, Vermeulen, Peter B., Dirix, Luc Y.

Source: In Cancer Letters 28 January 2015 356(2) Part B:872-879

Evaluation of the ability of adjuvant tamoxifen-benefit gene signatures to predict outcome of hormone-naive estrogen receptor-positive breast cancer patients treated with tamoxifen in the advanced setting

Authors: Sieuwerts, Anieta M., Lyng, Maria B., Meijer-van Gelder, Marion E., de Weerd, Vanja, Sweep, Fred C.G.J., Foekens, John A., Span, Paul N., Martens, John W.M., Ditzel, Henrik J.

Source: In Molecular Oncology December 2014 8(8):1679-1689