Cell cycle control in the early embryonic development of aquatic animal species

Authors: Siefert, Joseph C., Clowdus, Emily A., Sansam, Christopher L.

Source: In Comparative Biochemistry and Physiology, Part C December 2015 178:8-15

Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor–driven Programs

Authors: Linder, Simon, Severson, Tesa M., van der Mijn, Koen J.C., Nevedomskaya, Ekaterina, Siefert, Joseph C., Stelloo, Suzan, Pomerantz, Mark M., Freedman, Matthew L., van der Poel, Henk, Jerónimo, Carmen, Henrique, Rui, Bergman, Andries M., Zwart, Wilbert

Source: In European Urology November 2023 84(5):455-460

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.

Authors: Kneppers, Jeroen, Severson, Tesa M., Siefert, Joseph C., Schol, Pieter, Joosten, Stacey E. P., Yu, Ivan Pak Lok, Huang, Chia-Chi Flora, Morova, Tunç, Altıntaş, Umut Berkay, Giambartolomei, Claudia, Seo, Ji-Heui, Baca, Sylvan C., Carneiro, Isa, Emberly, Eldon, Pasaniuc, Bogdan, Jerónimo, Carmen, Henrique, Rui, Freedman, Matthew L., Wessels, Lodewyk F. A., Lack, Nathan A.

Source: Nature Communications; 11/30/2022, Vol. 13 Issue 1, p1-16, 16p

Subject Terms: PROSTATE cancer, SOMATIC mutation, ANDROGEN receptors, HETEROGENEITY, PROSTATE, GENE expression, PROSTATE tumors

Complement Factor H, Vitronectin, and Opticin Are Tyrosine-Sulfated Proteins of the Retinal Pigment Epithelium.

Authors: Kanan, Yogita¹ ykanan@ouhsc.edu, Siefert, Joseph C.¹, Kinter, Michael^2,3, Al-Ubaidi, Muayyad R.¹ muayyad-al-ubaidi@ouhsc.edu

Source: PLoS ONE. Aug2014, Vol. 9 Issue 8, p1-10. 10p.

Subject Terms: *COMPLEMENT factor H, *VITRONECTIN, *TYROSINE, *PHOTORECEPTORS, *EYE proteins, *PREDICTION models

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Germline Structural Variations Are Preferential Sites of DNA Replication Timing Plasticity during Development.

Authors: Hulke, Michelle L¹ (AUTHOR), Siefert, Joseph C² (AUTHOR), Sansam, Christopher L² (AUTHOR) Chris-Sansam@omrf.org, Koren, Amnon¹ (AUTHOR) Chris-Sansam@omrf.org

Source: Genome Biology & Evolution. Jun2019, Vol. 11 Issue 6, p1663-1678. 16p.

Subject Terms: *DNA replication, *SINGLE nucleotide polymorphisms, *GERM cells, *EMBRYOLOGY

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Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer.

Authors: Mayayo-Peralta, Isabel, Faggion, Beatrice, Hoekman, Liesbeth, Morris, Ben, Lieftink, Cor, Goldsbrough, Isabella, Buluwela, Lakjaya, Siefert, Joseph C., Post, Harm, Altelaar, Maarten, Beijersbergen, Roderick, Ali, Simak, Zwart, Wilbert, Prekovic, Stefan

Source: Cancers; Dec2021, Vol. 13 Issue 24, p6314-6314, 1p

Subject Terms: DISEASE progression, GENETIC mutation, DRUG tolerance, EPIDERMAL growth factor receptors, PROTEIN kinase inhibitors, ANTINEOPLASTIC agents, ESTROGEN receptors, CELL lines, BREAST tumors, DRUG resistance in cancer cells

Salivary Gland Hypofunction in tyrosylprotein sulfotransferase-2 Knockout Mice Is Due to Primary Hypothyroidism.

Authors: Westmuckett, Andrew D., Siefert, Joseph C., Tesiram, Yasvir A., Pinson, David M., Moore, Kevin L.

Source: PLoS ONE; Aug2013, Vol. 8 Issue 8, p1-1, 1p

Subject Terms: SALIVARY glands, TYROSYLPROTEIN sulfotransferase, HYPOTHYROIDISM, PROTEIN-tyrosine kinases, MEMBRANE proteins, SULFOTRANSFERASES, MAGNETIC resonance imaging, LABORATORY mice