Afatinib and Necitumumab in EGFR-Mutant NSCLC with Acquired Resistance to Tyrosine Kinase Inhibitors

Authors: Myall, Nathaniel J. ^a, Whisenant, Jennifer G. ^b, Neal, Joel W. ^a, Iams, Wade T. ^b, Reckamp, Karen L. ^c, York, Sally ^b, Berry, Lynne D. ^b, Shyr, Yu ^b, Horn, Leora ^b, Wakelee, Heather A. ^a, Padda, Sukhmani K. ^{a, d, ∗}

Source: In JTO Clinical and Research Reports February 2025 6(2)

VICTOR: Validation and inspection of cell type annotation through optimal regression

Authors: Chang, Chia-Jung ^{a, b, c}, Hsu, Chih-Yuan ^{a, b}, Liu, Qi ^{a, b, ⁎}, Shyr, Yu ^{a, b, ⁎}

Source: In Computational and Structural Biotechnology Journal December 2024 23:3270-3280

Characteristics of Lung Cancer Patients With Asymptomatic or Undiagnosed SARS-CoV-2 Infections

Authors: Somisetty, Medha, Mack, Philip C., Hsu, Chih-Yuan, Huang, Yuanhui, Gomez, Jorge E., Rodilla, Ananda M., Cagan, Jazz, Tavolacci, Sooyun C., Carreño, Juan Manuel, Brody, Rachel, Moore, Amy C., King, Jennifer C., Rohs, Nicholas C., Rolfo, Christian, Bunn, Paul A., Minna, John D., Bhalla, Sheena, Krammer, Florian, García-Sastre, Adolfo, Figueiredo, Jane C., Kazemian, Elham, Reckamp, Karen L., Merchant, Akil A., Nadri, Maimoona, Ahmed, Rafi, Ramalingam, Suresh S., Shyr, Yu, Hirsch, Fred R., Gerber, David E.

Source: In Clinical Lung Cancer November 2024 25(7):612-618

EVPsort: An Atlas of Small ncRNA Profiling and Sorting in Extracellular Vesicles and Particles

Authors: Chen, Hua-chang, Wang, Jing, Coffey, Robert J., Patton, James G., Weaver, Alissa M., Shyr, Yu, Liu, Qi

Source: In Journal of Molecular Biology 1 September 2024 436(17)

A Phase 1/2 Study to Evaluate the Safety and Activity of Nivolumab in Combination With Vorolanib, a Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitor, in Patients With Refractory Thoracic Tumors

Authors: Beckermann, Kathryn E., Bestvina, Christine M., El Osta, Badi, Sanborn, Rachel E., Borghaei, Hossein, Lammers, Philip Edward, Selvaggi, Giovanni, Whisenant, Jennifer G., Heimann-Nichols, Ellen, Berry, Lynne, Hsu, Chih-Yuan, Shyr, Yu, Horn, Leora, Wakelee, Heather

Source: In JTO Clinical and Research Reports February 2024 5(2)

Impact of Serial Intralesional Steroid Injections on Idiopathic Subglottic Stenosis

Authors: Hoffman, Matthew R., Patro, Ankita, Huang, Li‐Ching, Chen, Sheau‐Chiann, Berry, Lynn D., Gelbard, Alexander, Francis, David O., Anderson, Catherine, Amin, Milan R., Benninger, Michael S., Blumin, Joel H., Bock, Jonathan M., Bryson, Paul C., Castellanos, Paul F., Clary, Matthew S., Cohen, Seth M., Crawley, Brianna K., Dailey, Seth H., Daniero, James J., Alarcon, Alessandro, Donovan, Donald T., Edell, Eric S., Ekbom, Dale C., Fink, Daniel S., Franco, Ramon A., Garrett, C. Gaelyn, Guardiani, Elizabeth A., Hillel, Alexander T., Hoffman, Henry T., Hogikyan, Norman D., Howell, Rebecca J., Johns, Michael M., Kasperbauer, Jan L., Khosla, Sid M., Kinnard, Cheryl, Kupfer, Robbi A., Langerman, Alexander J., Lentz, Robert J., Lorenz, Robert R., Lott, David G., Makani, Samir S., Maldonado, Fabien, Mannion, Kyle, Matrka, Laura, McWhorter, Andrew J., Merati, Albert L., Mori, Matthew, Netterville, James L., O'Dell, Karla, Ongkasuwan, Julina, Postma, Gregory N., Reder, Lindsay S., Rohde, Sarah L., Richardson, Brent E., Rickman, Otis B., Rosen, Clark A., Rutter, Michael J., Sandhu, Guri S., Schindler, Joshua S., Schneider, G. Todd T., Shah, Rupali N., Sikora, Andrew G., Sinard, Robert J., Smith, Marshall E., Smith, Libby J., Soliman, Ahmed MS., Sveinsdottir, Sigríður, Van Daele, Douglas J., Veivers, David, Verma, Sunil P., Weinberger, Paul M., Weissbrod, Philip A., Wootten, Christopher T., Shyr, Yu

Source: Laryngoscope. 133(9):2255-2263

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189868290.0x000001&indx=1&recIds=ETOCvdc_100189868290.0x000001

Comparative Treatment Outcomes for Idiopathic Subglottic Stenosis: 5‐Year Update

Authors: Tierney, William S., Huang, Li‐Ching, Chen, Sheau‐Chiann, Berry, Lynn D., Anderson, Catherine, Amin, Milan R., Benninger, Michael S., Blumin, Joel H., Bock, Jonathan M., Bryson, Paul C., Castellanos, Paul F., Clary, Matthew S., Cohen, Seth M., Crawley, Brianna K., Dailey, Seth H., Daniero, James J., de Alarcon, Alessandro, Donovan, Donald T., Edell, Eric S., Ekbom, Dale C., Fink, Daniel S., Franco, Ramon A., Garrett, Catherine Gaelyn, Guardiani, Elizabeth A., Hillel, Alexander T., Hoffman, Henry T., Hogikyan, Norman D., Howell, Rebecca J., Johns, Michael M., Kasperbauer, Jan L., Khosla, Sid M., Kinnard, Cheryl, Kupfer, Robbi A., Langerman, Alexander J., Lentz, Robert J., Lorenz, Robert R., Lott, David G., Makani, Samir S., Maldonado, Fabien, Matrka, Laura, McWhorter, Andrew J., Merati, Albert L., Mori, Matthew, Netterville, James L., O'Dell, Karla, Ongkasuwan, Julina, Postma, Gregory N., Reder, Lindsay S., Rohde, Sarah L., Richardson, Brent E., Rickman, Otis B., Rosen, Clark A., Rohlfing, Matthew, Rutter, Michael J., Sandhu, Guri S., Schindler, Joshua S., Schneider, Glenn Todd, Shah, Rupali N., Sikora, Andrew G., Sinard, Robert J., Smith, Marshall E., Smith, Libby J., Soliman, Ahmed M. S., Sveinsdóttir, Sigríður, Veivers, David, Verma, Sunil P., Weinberger, Paul M., Weissbrod, Philip A., Wootten, Christopher T., Shyr, Yu, Francis, David O., Gelbard, Alexander

Source: Otolaryngology--head and neck surgery. 168(6):1570-1575

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186845841.0x000001&indx=1&recIds=ETOCvdc_100186845841.0x000001

Primary endpoints to assess the efficacy of novel therapeutic approaches in epidermal growth factor receptor-mutated, surgically resectable non-small cell lung cancer: A review

Authors: Blakely, Collin M., Weder, Walter, Bubendorf, Lukas, He, Jianxing, Majem, Margarita, Shyr, Yu, Chaft, Jamie E.

Source: Lung cancer. 177:59-72

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183616152.0x000001&indx=1&recIds=ETOCvdc_100183616152.0x000001

Breakthrough SARS-CoV-2 infections among patients with cancer following two and three doses of COVID-19 mRNA vaccines: a retrospective observational study from the COVID-19 and Cancer Consortium

Authors: Choueiri, Toni K., Labaki, Chris, Bakouny, Ziad, Hsu, Chih-Yuan, Schmidt, Andrew L., de Lima Lopes, Gilberto, Jr., Hwang, Clara, Singh, Sunny R.K., Jani, Chinmay, Weissmann, Lisa B., Griffiths, Elizabeth A., Halabi, Susan, Wu, Ulysses, Berg, Stephanie, O'Connor, Timothy E., Wise-Draper, Trisha M., Panagiotou, Orestis A., Klein, Elizabeth J., Joshi, Monika, Yared, Fares, Dutra, Miriam Santos, Gatson, Na Tosha N., Blau, Sibel, Singh, Harpreet, Nanchal, Rahul, McKay, Rana R., Nonato, Taylor K., Quinn, Ryann, Rubinstein, Samuel M., Puc, Matthew, Mavromatis, Blanche H., Vikas, Praveen, Faller, Bryan, Zaren, Howard A., Del Prete, Salvatore, Russell, Karen, Reuben, Daniel Y., Accordino, Melissa K., Friese, Christopher R., Mishra, Sanjay, Rivera, Donna R., Shyr, Yu, Farmakiotis, Dimitrios, Warner, Jeremy L.

Source: In The Lancet Regional Health - Americas March 2023 19

scDemultiplex: An iterative beta-binomial model-based method for accurate demultiplexing with hashtag oligos

Authors: Huang, Li-Ching, Stolze, Lindsey K., Chen, Hua-Chang, Gelbard, Alexander, Shyr, Yu, Liu, Qi, Sheng, Quanhu

Source: In Computational and Structural Biotechnology Journal 2023 21:4044-4055

Endogenous sex hormones, aromatase activity and lung cancer risk in postmenopausal never‐smoking women

Authors: Zhao, Yingya, Gao, Yu‐Tang, Zhang, Xianglan, Rockwood, Alan L., Kushnir, Mark M., Cai, Qiuyin, Wu, Jie, Shi, Jiajun, Lan, Qing, Rothman, Nathaniel, Shyr, Yu, Shu, Xiao‐Ou, Zheng, Wei, Yang, Gong

Source: International journal of cancer. 151(5):699-707

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187492785.0x000001&indx=1&recIds=ETOCvdc_100187492785.0x000001

A Single Nucleotide Polymorphism in SH2B3/LNK Promotes Hypertension Development and Renal Damage

Authors: Alexander, Matthew R., Hank, Samuel, Dale, Bethany L., Himmel, Lauren, Zhong, Xue, Smart, Charles D., Fehrenbach, Daniel J., Chen, Yuhan, Prabakaran, Nitin, Tirado, Brian, Centrella, Megan, Ao, Mingfang, Du, Liping, Shyr, Yu, Levy, Daniel, Madhur, Meena S.

Source: Circulation research. 131(9):731-747

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183179276.0x000001&indx=1&recIds=ETOCvdc_100183179276.0x000001

Scalable and model-free detection of spatial patterns and colocalization

Authors: Liu, Qi, Hsu, Chih-Yuan, Shyr, Yu

Source: Genome research. 32(9):1736-1745

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630313477&indx=1&recIds=ETOCRN630313477

Dysregulated ligand–receptor interactions from single-cell transcriptomics

Authors: Liu, Qi, Hsu, Chih-Yuan, Li, Jia, Shyr, Yu

Source: Bioinformatics. 38(12):3216-3221

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152072884.0x000001&indx=1&recIds=ETOCvdc_100152072884.0x000001

Preoperative and Postoperative Systemic Therapy for Operable Non–Small-Cell Lung Cancer

Authors: Chaft, Jamie E., Shyr, Yu, Sepesi, Boris, Forde, Patrick M.

Source: Journal of clinical oncology. 40(6):546-555

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151748582.0x000001&indx=1&recIds=ETOCvdc_100151748582.0x000001

COVID-19 vaccination and breakthrough infections in patients with cancer

Authors: Choueiri, T.K., Duma, N., Farmakiotis, D., Grivas, P., de Lima Lopes, G., Jr., Painter, C.A., Peters, S., Rini, B.I., Shah, D.P., Thompson, M.A., Warner, J.L., Schmidt, A.L. ^†, Labaki, C. ^†, Hsu, C.-Y. ^†, Bakouny, Z. ^†, Balanchivadze, N., Berg, S.A., Blau, S., Daher, A., El Zarif, T., Friese, C.R., Griffiths, E.A., Hawley, J.E., Hayes-Lattin, B., Karivedu, V., Latif, T., Mavromatis, B.H., McKay, R.R., Nagaraj, G., Nguyen, R.H., Panagiotou, O.A., Portuguese, A.J., Puc, M., Santos Dutra, M., Schroeder, B.A., Thakkar, A., Wulff-Burchfield, E.M., Mishra, S., Shyr, Yu ^†

Source: In Annals of Oncology March 2022 33(3):340-346

Phytoestrogens and lung cancer risk: a nested case-control study in never-smoking Chinese women

Authors: Li, Mengjie, Cai, Qiuyin, Gao, Yu-Tang, Franke, Adrian A, Zhang, Xianglan, Zhao, Yingya, Wen, Wanqing, Lan, Qing, Rothman, Nathaniel, Shyr, Yu, Shu, Xiao-Ou, Zheng, Wei, Yang, Gong ^*

Source: In The American Journal of Clinical Nutrition March 2022 115(3):643-651

Lung Cancer and Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Identifying Important Knowledge Gaps for Investigation

Authors: Rolfo, Christian, Meshulami, Noy, Russo, Alessandro, Krammer, Florian, García-Sastre, Adolfo, Mack, Philip C., Gomez, Jorge E., Bhardwaj, Nina, Benyounes, Amin, Sirera, Rafael, Moore, Amy, Rohs, Nicholas, Henschke, Claudia I., Yankelevitz, David, King, Jennifer, Shyr, Yu, Bunn, Paul A., Jr., Minna, John D., Hirsch, Fred R.

Source: In Journal of Thoracic Oncology February 2022 17(2):214-227

Immu-Mela: An open resource for exploring immunotherapy-related multidimensional genomic profiles in melanoma

Authors: Yang, Jing, Zhao, Shilin, Wang, Jing, Sheng, Quanhu, Liu, Qi, Shyr, Yu

Source: In Journal of Genetics and Genomics 20 May 2021 48(5):361-368

Biomarker Discovery and Validation: Statistical Considerations

Authors: Ou, Fang-Shu, Michiels, Stefan, Shyr, Yu, Adjei, Alex A., Oberg, Ann L.

Source: In Journal of Thoracic Oncology April 2021 16(4):537-545