MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice

Authors: Shilpak Bele, Shravan Babu Girada, Aramita Ray, Abhishek Gupta, Srinivas Oruganti, Phanithi Prakash Babu, Rahul SR Rayalla, Shashi Vardhan Kalivendi, Ahamed Ibrahim, Vishwajeet Puri, Venkateswar Adalla, Madhumohan R Katika, Richard DiMarchi, Prasenjit Mitra

Source: eLife, Vol 9 (2020)

Subject Terms: glucagon-like peptide-1 receptor, HDAC inhibition, insulin secretion, obesity, energy expenditure, glycemic control, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/52212; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/bc7951a1758043849dd74d907661bb2c

Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment

Authors: Shravan Babu Girada, Ramya S. Kuna, Shilpak Bele, Zhimeng Zhu, N.R. Chakravarthi, Richard D. DiMarchi, Prasenjit Mitra

Source: Molecular Metabolism, Vol 6, Iss 10, Pp 1173-1185 (2017)

Subject Terms: GLP-1 receptor, Rab5, Cyclic AMP, Insulin secretion, Gαs, Beta arrestin-1, Pancreatic beta cells, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221287781630312X; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/eca9030a2630473eac6dfff70f2f8824