What Do Patients Say About Their Disease Symptoms? Deep Multilabel Text Classification With Human-in-the-Loop Curation for Automatic Labeling of Patient Self Reports of Problems

Authors: Arbatti, Lakshmi, Hosamath, Abhishek, Ramanarayanan, Vikram, Shoulson, Ira

Subject Terms: Computer Science - Computation and Language, Computer Science - Machine Learning, Electrical Engineering and Systems Science - Audio and Speech Processing

Access URL: http://arxiv.org/abs/2305.04905

What Parkinson's disease patients say in their own words about their mood and anxiety symptoms

Authors: Anderson, Karen E. ^{a, ⁎}, Marras, Connie ^b, Amara, Amy ^c, Chahine, Lana M. ^d, Eberly, Shirley ^e, Hosamath, Abhishek ^f, Kinel, Daniel ^g, Mantri, Sneha ^h, Mathur, Soania ⁱ, Oakes, David ^e, Purks, Jennifer L. ^e, Standaert, David G. ^j, Weintraub, Daniel ^k, Shoulson, Ira ^{e, f}, Arbatti, Lakshmi ^f

Source: In Parkinsonism and Related Disorders January 2025 130

Genetic modifiers of Huntington disease differentially influence motor and cognitive domains

Authors: Lee, Jong-Min, Huang, Yuan, Orth, Michael, Gillis, Tammy, Siciliano, Jacqueline, Hong, Eunpyo, Mysore, Jayalakshmi Srinidhi, Lucente, Diane, Wheeler, Vanessa C., Seong, Ihn Sik, McLean, Zachariah L., Mills, James A., McAllister, Branduff, Lobanov, Sergey V., Massey, Thomas H., Ciosi, Marc, Landwehrmeyer, G. Bernhard, Paulsen, Jane S., Dorsey, E. Ray, Shoulson, Ira, Sampaio, Cristina, Monckton, Darren G., Kwak, Seung, Holmans, Peter, Jones, Lesley, MacDonald, Marcy E., Long, Jeffrey D., Gusella, James F.

Source: In The American Journal of Human Genetics 5 May 2022 109(5):885-899

Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington’s Disease

Authors: Ellis, Natalie, Tee, Amelia, McAllister, Branduff, Massey, Thomas, McLauchlan, Duncan, Stone, Timothy, Correia, Kevin, Loupe, Jacob, Kim, Kyung-Hee, Barker, Douglas, Hong, Eun Pyo, Chao, Michael J., Long, Jeffrey D., Lucente, Diane, Vonsattel, Jean Paul G., Pinto, Ricardo Mouro, Elneel, Kawther Abu, Ramos, Eliana Marisa, Mysore, Jayalakshmi Srinidhi, Gillis, Tammy, Wheeler, Vanessa C., Medway, Christopher, Hall, Lynsey, Kwak, Seung, Sampaio, Cristina, Ciosi, Marc, Maxwell, Alastair, Chatzi, Afroditi, Monckton, Darren G., Orth, Michael, Landwehrmeyer, G. Bernhard, Paulsen, Jane S., Shoulson, Ira, Myers, Richard H., van Duijn, Erik, Rickards, Hugh, MacDonald, Marcy E., Lee, Jong-min, Gusella, James F., Jones, Lesley, Holmans, Peter

Source: In Biological Psychiatry 1 May 2020 87(9):857-865

CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset

Authors: Lee, Jong-Min, Correia, Kevin, Loupe, Jacob, Kim, Kyung-Hee, Barker, Douglas, Hong, Eun Pyo, Chao, Michael J., Long, Jeffrey D., Lucente, Diane, Vonsattel, Jean Paul G., Pinto, Ricardo Mouro, Abu Elneel, Kawther, Ramos, Eliana Marisa, Mysore, Jayalakshmi Srinidhi, Gillis, Tammy, Wheeler, Vanessa C., MacDonald, Marcy E., Gusella, James F., McAllister, Branduff, Massey, Thomas, Medway, Christopher, Stone, Timothy C., Hall, Lynsey, Jones, Lesley, Holmans, Peter, Kwak, Seung, Ehrhardt, Anka G., Sampaio, Cristina, Ciosi, Marc, Maxwell, Alastair, Chatzi, Afroditi, Monckton, Darren G., Orth, Michael, Landwehrmeyer, G. Bernhard, Paulsen, Jane S., Dorsey, E. Ray, Shoulson, Ira, Myers, Richard H.

Source: In Cell 8 August 2019 178(4):887-900

A comprehensive review of the FDA-approved labels of diabetes drugs: Indications, safety, and emerging cardiovascular safety data

Authors: Gourgari, Evgenia, Wilhelm, Erin E., Hassanzadeh, Hamid, Aroda, Vanita R., Shoulson, Ira

Source: In Journal of Diabetes and Its Complications December 2017 31(12):1719-1727

Prediction of cognition in Parkinson's disease with a clinical–genetic score: a longitudinal analysis of nine cohorts

Authors: Scherzer, Clemens R., Hyman, Bradley T., Ivinson, Adrian J., Trisini-Lipsanopoulos, Ana, Franco, Daly, Burke, Kyle, Sudarsky, Lewis R., Hayes, Michael T., Umeh, Chizoba C., Sperling, Reisa, Growdon, John H., Schwarzschild, Michael A., Hung, Albert Y., Flaherty, Alice W., Blacker, Deborah, Wills, Anne-Marie, Sohur, U. Shivraj, Mejia, Nicte I., Viswanathan, Anand, Gomperts, Stephen N., Khurana, Vikram, Albers, Mark W., Alora-Palli, Maria, McGinnis, Scott, Sharma, Nutan, Dickerson, Bradford, Frosch, Matthew, Gomez-Isla, Teresa, Greenberg, Steven, Gusella, James, Hedden, Trey, Hedley-Whyte, E Tessa, Koenig, Aaron, Marquis-Sayagues, Marta, Marshall, Gad, Okereke, Olivia, Stemmer-Rachaminov, Anat, Kloppenburg, Jessica, Schlossmacher, Michael G., Selkoe, Dennis J., Yi, Thomas, Locascio, Joseph J., Li, Haining, Stalberg, Gabriel, Liao, Zhixiang, Barker, Roger, Foltynie, Tom, Williams-Gray, Caroline, Robbins, Trevor, Brayne, Carol, Mason, Sarah, Winder-Rhodes, Sophie, Breen, David P, Cummins, Gemma, Evans, Jonathan, van Hilten, Jacobus J., Marinus, Johan, Corvol, Jean-Christophe, Brice, Alexis, Elbaz, Alexis, Mallet, Alain, Vidailhet, Marie, Bonnet, Anne-Marie, Bonnet, Cecilia, Grabli, David, Hartmann, Andreas, Klebe, Stephan, Lacomblez, Lucette, Mangone, Graziella, Bourdain, Frédéric, Brandel, Jean-Philippe, Derkinderen, Pascal, Durif, Franck, Mesnage, Valérie, Pico, Fernando, Rascol, Olivier, Brefel-Courbon, Christine, Ory-Magne, Fabienne, Forlani, Sylvie, Lesage, Suzanne, Tahiri, Khadija, Albin, Roger, Alcalay, Roy, Ascherio, Alberto, Bowman, Dubois, Chen-Plotkin, Alice, Dawson, Ted, Dewey, Richard, German, Dwight, Saunders-Pullman, Rachel, Scherzer, Clemens, Vaillancourt, David, Petyuk, Vladislav, West, Andy, Zhang, Jing, Liu, Ganqiang, Locascio, Joseph J, Boot, Brendon, Page, Kara, Jansen, Iris E, Tanner, Caroline M, Lang, Anthony E, Eberly, Shirley, Ravina, Bernard, Shoulson, Ira, Cormier-Dequaire, Florence, Heutink, Peter, van Hilten, Jacobus J, Barker, Roger A, Williams-Gray, Caroline H, Scherzer, Clemens R

Source: In The Lancet Neurology August 2017 16(8):620-629

In Their Own Words: Fears Expressed by People with Parkinson's Disease in an Online Symptom Database.

Authors: Mantri, Sneha, Purks, Jennifer L., Kinel, Daniel, Arbatti, Lakshmi, Hosamath, Abhishek, Allen, Allison, Amara, Amy, Anderson, Karen, Chahine, Lana M., Eberly, Shirley, Mathur, Soania, Standaert, David, Oakes, David, Weintraub, Daniel, Shoulson, Ira, Marras, Connie

Source: Journal of Parkinson's Disease; 2024, Vol. 14 Issue 4, p865-872, 8p

Subject Terms: PARKINSON'S disease, SYMPTOMS, ONLINE databases, DATABASES, COGNITION disorders, MOVEMENT disorders

Optimal Expectations and Limited Medical Testing: Evidence from Huntington Disease: Corrigendum

Authors: Oster, Emily, Shoulson, Ira, Dorsey, E. Ray

Source: The American Economic Review, 2016 Jun 01. 106(6), 1562-1565.

Access URL: https://www.jstor.org/stable/43861132

Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

Authors: Lesage, Suzanne, Tison, François, Vidailhet, Marie, Corvol, Jean-Christophe, Agid, Yves, Anheim, Mathieu, Bonnet, Anne-Marie, Borg, Michel, Broussolle, Emmanuel, Damier, Philippe, Destée, Alain, Dürr, Alexandra, Durif, Franck, Krack, Paul, Klebe, Stephan, Lohmann, Ebba, Martinez, Maria, Pollak, Pierre, Rascol, Olivier, Tranchant, Christine, Vérin, Marc, Viallet, François, Brice, Alexis, Majounie, Elisa, Corvol, Jean Christophe, Nalls, Michael A., Hernandez, Dena G., Gibbs, J. Raphael, Arepalli, Sampath, Barker, Roger A., Ben-Shlomo, Yoav, Berg, Daniela, Bettella, Francesco, Bhatia, Kailash, de Bie, Rob M.A., Biffi, Alessandro, Bloem, Bastiaan R., Bochdanovits, Zoltan, Bonin, Michael, Bras, Jose M., Brockmann, Kathrin, Brooks, Janet, Burn, David J., Charlesworth, Gavin, Chen, Honglei, Chinnery, Patrick F., Chong, Sean, Clarke, Carl E., Cookson, Mark R., Counsell, Carl, Dartigues, Jean-François, Deloukas, Panos, Deuschl, Günther, Dexter, David T., van Dijk, Karin D., Dillman, Allissa, Dong, Jing, Durif, Frank, Edkins, Sarah, Escott-Price, Valentina, Evans, Jonathan R., Foltynie, Thomas, Gao, Jianjun, Gardner, Michelle, Goate, Alison, Gray, Emma, Guerreiro, Rita, Harris, Clare, van Hilten, Jacobus J., Hofman, Albert, Hollenbeck, Albert, Holmans, Peter, Holton, Janice, Hu, Michèle, Huang, Xuemei, Huber, Heiko, Hudson, Gavin, Hunt, Sarah E., Huttenlocher, Johanna, Illig, Thomas, Jónsson, Pálmi V., Kilarski, Laura L., Jansen, Iris E., Lambert, Jean-Charles, Langford, Cordelia, Lees, Andrew, Lichtner, Peter, Limousin, Patricia, Lopez, Grisel, Lorenz, Delia, Lubbe, Steven, Lungu, Codrin, Martinez, María, Mätzler, Walter, McNeill, Alisdair, Moorby, Catriona, Moore, Matthew, Morrison, Karen E., Mudanohwo, Ese, O’Sullivan, Sean S., Owen, Michael J., Pearson, Justin, Perlmutter, Joel S., Pétursson, Hjörvar, Plagnol, Vincent, Post, Bart, Potter, Simon, Ravina, Bernard, Revesz, Tamas, Riess, Olaf, Rivadeneira, Fernando, Rizzu, Patrizia, Ryten, Mina, Saad, Mohamad, Simón-Sánchez, Javier, Sawcer, Stephen, Schapira, Anthony, Scheffer, Hans, Schulte, Claudia, Sharma, Manu, Shaw, Karen, Sheerin, Una-Marie, Shoulson, Ira, Shulman, Joshua, Sidransky, Ellen, Spencer, Chris C.A., Stefánsson, Hreinn, Stefánsson, Kári, Stockton, Joanna D., Strange, Amy, Talbot, Kevin, Tanner, Carlie M., Tashakkori-Ghanbaria, Avazeh, Trabzuni, Daniah, Traynor, Bryan J., Uitterlinden, André G., Velseboer, Daan, Walker, Robert, van de Warrenburg, Bart, Wickremaratchi, Mirdhu, Williams-Gray, Caroline H., Winder-Rhodes, Sophie, Wurster, Isabel, Williams, Nigel, Morris, Huw R., Heutink, Peter, Hardy, John, Wood, Nicholas W., Gasser, Thomas, Singleton, Andrew B., Drouet, Valérie, Deramecourt, Vincent, Jacoupy, Maxime, Nicolas, Aude, Cormier-Dequaire, Florence, Hassoun, Sidi Mohamed, Pujol, Claire, Ciura, Sorana, Erpapazoglou, Zoi, Usenko, Tatiana, Maurage, Claude-Alain, Sahbatou, Mourad, Liebau, Stefan, Ding, Jinhui, Bilgic, Basar, Emre, Murat, Erginel-Unaltuna, Nihan, Guven, Gamze, Leutenegger, Anne-Louise, Durr, Alexandra, Deleuze, Jean-François, Tazir, Meriem, Kabashi, Edor, Singleton, Andrew, Corti, Olga

Source: In The American Journal of Human Genetics 3 March 2016 98(3):500-513

What Huntington's Disease Patients Say About Their Illness: An Online Direct-to-Participant Pilot Study.

Authors: Anderson, Karen E., Arbatti, Lakshmi, Hosamath, Abhishek, Feigin, Andrew, Goldstein, Jody, Kayson, Elise, Kinsler, Brett L., Falanga, Lauren, Denise, Lynn, Carlozzi, Noelle E., Frank, Samuel, Jackson, Katie, Kostyk, Sandra, Purks, Jennifer L., Serbin, Kenneth P., Kinel, Shari, Beck, Christopher A., Shoulson, Ira

Source: Journal of Huntington's Disease; 2024, Vol. 13 Issue 2, p237-248, 12p

Subject Terms: HUNTINGTON disease, NATURAL language processing, PATIENT participation, MEDICAL research, ALASKA Natives

Association between Subjective Cognitive Complaints and Incident Functional Impairment in Parkinson’s Disease.

Authors: Weintraub, Daniel, Marras, Connie, Amara, Amy, Anderson, Karen E., Chahine, Lana M., Eberly, Shirley, Hosamath, Abhishek, Kinel, Daniel, Mantri, Sneha, Mathur, Soania, Oakes, David, Purks, Jennifer L., Standaert, David G., Shoulson, Ira, Arbatti, Lakshmi

Source: Movement Disorders; Apr2024, Vol. 39 Issue 4, p706-714, 9p

Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

Authors: Lee, Jong-Min, Wheeler, Vanessa C., Chao, Michael J., Vonsattel, Jean Paul G., Pinto, Ricardo Mouro, Lucente, Diane, Abu-Elneel, Kawther, Ramos, Eliana Marisa, Mysore, Jayalakshmi Srinidhi, Gillis, Tammy, MacDonald, Marcy E., Gusella, James F., Harold, Denise, Stone, Timothy C., Escott-Price, Valentina, Han, Jun, Vedernikov, Alexey, Holmans, Peter, Jones, Lesley, Kwak, Seung, Mahmoudi, Mithra, Orth, Michael, Landwehrmeyer, G. Bernhard, Paulsen, Jane S., Dorsey, E. Ray, Shoulson, Ira, Myers, Richard H.

Source: In Cell 30 July 2015 162(3):516-526

Internal tremor in people with Parkinson’s Disease: Demographic characteristics and comorbid symptoms

Authors: Chahine, Lana M. ^{a, ⁎}, Arbatti, Lakshmi ^b, Hosamath, Abhishek ^b, Amara, Amy ^c, Anderson, Karen E. ^d, Purks, Jennifer ^{e, f}, Eberly, Shirley ^g, Kinel, Daniel ^e, Mantri, Sneha ^h, Mathur, Soania ⁱ, Oakes, David ^f, Standaert, David G. ^j, Weintraub, Daniel ^k, Shoulson, Ira ^{b, e}, Marras, Connie ^l

Source: In Clinical Parkinsonism & Related Disorders 2023 9

Experimental Therapeutics of Neurodegenerative Disorders: Unmet Needs

Authors: Shoulson, Ira

Source: Science, 1998 Nov 01. 282(5391), 1072-1074.

Access URL: https://www.jstor.org/stable/2897347

Limited Life Expectancy, Human Capital and Health Investments

Authors: Oster, Emily, Shoulson, Ira, Dorsey, E. Ray

Source: The American Economic Review, 2013 Aug 01. 103(5), 1977-2002.

Access URL: https://www.jstor.org/stable/42920636

Optimal Expectations and Limited Medical Testing: Evidence from Huntington Disease

Authors: Oster, Emily, Shoulson, Ira, Dorsey, E. Ray

Source: The American Economic Review, 2013 Apr 01. 103(2), 804-830.

Access URL: https://www.jstor.org/stable/23469683

What Patients Say: Large-Scale Analyses of Replies to the Parkinson's Disease Patient Report of Problems (PD-PROP).

Authors: Marras, Connie, Arbatti, Lakshmi, Hosamath, Abhishek, Amara, Amy, Anderson, Karen E., Chahine, Lana M., Eberly, Shirley, Kinel, Dan, Mantri, Sneha, Mathur, Soania, Oakes, David, Purks, Jennifer L., Standaert, David G., Tanner, Caroline M., Weintraub, Daniel, Shoulson, Ira

Source: Journal of Parkinson's Disease; 2023, Vol. 13 Issue 5, p757-767, 11p

Subject Terms: PARKINSON'S disease, NATURAL language processing, REPORTING of diseases, MACHINE learning

Altered cholesterol and fatty acid metabolism in Huntington disease

Authors: Block, Robert C., Dorsey, E. Ray, Beck, Christopher A., Brenna, J. Thomas, Shoulson, Ira

Source: In Journal of Clinical Lipidology 2010 4(1):17-23

Genetic adverse selection: Evidence from long-term care insurance and Huntington disease

Authors: Oster, Emily, Shoulson, Ira, Quaid, Kimberly, Dorsey, E. Ray

Source: In Journal of Public Economics 2010 94(11):1041-1050