Gene Copy Deletion of STK11, KEAP1, and SMARCA4: Clinicopathologic Features and Association With the Outcomes of Immunotherapy With or Without Chemotherapy in Nonsquamous NSCLC

Authors: Gandhi, Malini M. ^a, Elkrief, Arielle ^b, Moore, Catherine Gutierrez ^a, Ricciuti, Biagio ^a, Alessi, Joao V. ^a, Richards, Allison L. ^c, Tischfield, Sam ^c, Williams, Jessica ^d, Lamberti, Giuseppe ^a, Pecci, Federica ^a, Di Federico, Alessandro ^a, Makarem, Maisam ^a, Johnson, Bruce E. ^a, Nishino, Mizuki ^e, Sholl, Lynette M. ^d, Schoenfeld, Adam J. ^b, Awad, Mark M. ^{b, ∗}

Source: In Journal of Thoracic Oncology January 2025

Clear Cell Stromal Tumor of the Lung: Clinicopathologic, Immunohistochemical, and Molecular Characterization of Eight Cases

Authors: Odintsov, Igor ^a, Isaacson, Alexandra ^b, Fritchie, Karen J. ^b, Hung, Yin P. ^c, Khoshnoodi, Pooria ^d, Sholl, Lynette M. ^a, Fletcher, Christopher D.M. ^a, Anderson, William J. ^{a, ∗}

Source: In Modern Pathology January 2025 38(1)

Fluorescence in-situ hybridization assessment of spindle cell-rich testicular sex cord stromal tumors demonstrates multiple chromosomal gains across histologic subtypes

Authors: Acosta, Andres Martin, Fletcher, Christopher D.M., Sholl, Lynette M., van Leenders, Geert JLH., Oliva, Esther, Cornejo, Kristine M., Repetto, Federico, Collins, Katrina, Idrees, Muhammad T., Hirsch, Michelle S., Trpkov, Kiril, Ulbright, Thomas M., Bridge, Julia A.

Source: In Human Pathology November 2024 153

Three-Year Overall Survival Outcomes and Correlative Analyses in Patients With NSCLC and High (50%–89%) Versus Very High (≥90%) Programmed Death-Ligand 1 Expression Treated With First-Line Pembrolizumab or Cemiplimab

Authors: Ricciuti, Biagio, Elkrief, Arielle, Lin, Jessica, Zhang, Jianjun, Alessi, Joao V., Lamberti, Giuseppe, Gandhi, Malini, Di Federico, Alessandro, Pecci, Federica, Wang, Xinan, Makarem, Maisam, Hidalgo Filho, Cassio Murilo, Gorria, Teresa, Saini, Arushi, Pabon, Cindy, Lindsay, James, Pfaff, Kathleen L., Welsh, Emma L., Nishino, Mizuki, Sholl, Lynette M., Rodig, Scott, Kilickap, Saadettin, Rietschel, Petra, McIntyre, Debra AG., Pouliot, Jean-Francois, Altan, Mehmet, Gainor, Justin F., Heymach, John V., Schoenfeld, Adam J., Awad, Mark M.

Source: In JTO Clinical and Research Reports September 2024 5(9)

Initial Chemotherapy for Locally Advanced and Metastatic NUT Carcinoma

Authors: Luo, Jia, Sanchez, Michelle, Lee, Elinton, Hertzler, Hans, Luong, Nhi, Mazzola, Emanuele, Finstein, Bryanna, Tamen, Rubii, Brisbane, Gifty, Nguyen, Tom, Paik, Paul K., Chaft, Jamie E., Cheng, Michael L., Khalil, Hassan, Piha-Paul, Sarina A., Sholl, Lynette M., Nishino, Mizuki, Jänne, Pasi A., DuBois, Steven G., Hanna, Glenn J., Shapiro, Geoffrey I., French, Christopher A.

Source: In Journal of Thoracic Oncology May 2024 19(5):829-838

Prevalence and Therapeutic Targeting of High-Level ERBB2 Amplification in NSCLC

Authors: Odintsov, Igor, Makarem, Maisam, Nishino, Mizuki, Bachert, Sara Emily, Zhang, Tom, LoPiccolo, Jaclyn, Paweletz, Cloud P., Gokhale, Prafulla C., Ivanova, Elena, Saldanha, Aisha, Rudin, Charles M., Lockwood, William W., Ladanyi, Marc, Somwar, Romel, Jänne, Pasi A., Sholl, Lynette M.

Source: In Journal of Thoracic Oncology May 2024 19(5):732-748

A Panel-Based Mutational Signature of Mismatch Repair Deficiency is Associated With Durable Response to Pembrolizumab in Metastatic Castration-Resistant Prostate Cancer

Authors: Boiarsky, Daniel, Gulhan, Doga C., Savignano, Hunter, Lakshminarayanan, Gitanjali, McClure, Heather M., Silver, Rebecca, Hirsch, Michelle S., Sholl, Lynette M., Choudhury, Atish D., Ananda, Guruprasad, Park, Peter J., Tewari, Alok K., Berchuck, Jacob E.

Source: In Clinical Genitourinary Cancer April 2024 22(2):558-568

Programmed Death Ligand-1 and Tumor Mutation Burden Testing of Patients With Lung Cancer for Selection of Immune Checkpoint Inhibitor Therapies.

Authors: Sholl, Lynette M.¹ lmsholl@bwh.harvard.edu, Awad, Mark², Roy, Upal Basu³, Beasley, Mary Beth⁴, Cartun, Richard Walter⁵, Hwang, David M.⁶, Kalemkerian, Gregory⁷, Lopez-Rios, Fernando⁸, Mino-Kenudson, Mari⁹, Paintal, Ajit¹⁰, Reid, Kearin¹¹, Ritterhouse, Lauren^12,13, Souter, Lesley A.¹⁴, Swanson, Paul E.¹⁵, Ventura, Christina B.¹⁶, Furtado, Larissa V.¹⁷

Source: Archives of Pathology & Laboratory Medicine. Jul2024, Vol. 148 Issue 7, p757-774. 18p.

Subject Terms: *MEDICAL protocols, *PATIENT selection, *PROGRAMMED death-ligand 1, *IMMUNOTHERAPY, *CANCER patients, *TUMOR markers, *IMMUNE checkpoint inhibitors, *SYSTEMATIC reviews, *LUNG tumors, *GENETIC mutation, *LUNG cancer

Company/Entity: COLLEGE of American Pathologists

Prognostic and predictive biomarkers in non-small cell lung carcinoma

Authors: Odintsov, Igor, Sholl, Lynette M.

Source: In Pathology March 2024 56(2):192-204

Testicular Neoplasms With Sex Cord and Stromal Components Harbor a Recurrent Pattern of Chromosomal Gains

Authors: Acosta, Andres M., Sholl, Lynette M., Maclean, Fiona, Kao, Chia-Sui, Ulbright, Thomas M.

Source: In Modern Pathology January 2024 37(1)

Distinctive Nested Glomoid Neoplasm

Authors: Papke, David J., Dickson, Brendan C., Oliveira, Andre M., Sholl, Lynette M., Fletcher, Christopher D.M.

Source: American journal of surgical pathology. 47(1):12-24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186832438.0x000001&indx=1&recIds=ETOCvdc_100186832438.0x000001

Acquiring tissue for advanced lung cancer diagnosis and comprehensive biomarker testing: A National Lung Cancer Roundtable best‐practice guide

Authors: Fox, Adam H., Nishino, Mizuki, Osarogiagbon, Raymond U., Rivera, M. Patricia, Rosenthal, Lauren S., Smith, Robert A., Farjah, Farhood, Sholl, Lynette M., Silvestri, Gerard A., Johnson, Bruce E.

Source: CA. 73(4):358-375

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186566317.0x000001&indx=1&recIds=ETOCvdc_100186566317.0x000001

Large cell calcifying Sertoli cell tumour: molecular and immunohistochemical assessment of a series comprising non‐metastasising and metastasising neoplasms

Authors: Yu, Sanhong, Sholl, Lynette M, Siegmund, Stephanie, Ulbright, Thomas M, Collins, Katrina, Colecchia, Maurizio, Pilar Gonzalez‐Peramato, Maria, Michalová, Květoslava, Gordetsky, Jennifer B, Cornejo, Kristine M, Kao, Chia‐Sui, Wobker, Sara E, Vargas, Sara O, Maclean, Fiona, Idrees, Muhammad T, Anderson, William J, Fletcher, Christopher D M, Acosta, Andres M

Source: Histopathology. 82(7):1079-1088

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182817955.0x000001&indx=1&recIds=ETOCvdc_100182817955.0x000001

Updates in pathology and molecular diagnostics to inform the evolving landscape of thoracic surgery and oncology

Authors: Naso, Julia, Lo, Ying‐Chun, Sholl, Lynette M.

Source: Journal of surgical oncology. 127(2):244-257

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170783151.0x000001&indx=1&recIds=ETOCvdc_100170783151.0x000001

Myoid gonadal stromal tumours are characterised by recurrent chromosome‐level copy number gains: molecular assessment of a multi‐institutional series

Authors: Collins, Katrina, Sholl, Lynette M., Siegmund, Stephanie, Dickson, Brendan C., Colecchia, Maurizio, Michalová, Květoslava, Hwang, Michael, Ulbright, Thomas M., Kao, Chia‐Sui, Leenders, Geert J.L.H., Mehta, Vikas, Trpkov, Kiril, Yilmaz, Asli, Cimadamore, Alessia, Matoso, Andres, Epstein, Jonathan I., Maclean, Fiona, Comperat, Eva, Anderson, William J., Fletcher, Christopher D.M., Acosta, Andrés M.

Source: Histopathology. 82(3):431-438

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171086503.0x000001&indx=1&recIds=ETOCvdc_100171086503.0x000001

PAX1 expression in thymic epithelial neoplasms and morphologic mimics

Authors: Parrack, Paige H., Hornick, Jason L., Sholl, Lynette M.

Source: In Human Pathology December 2023 142:7-14

Impact of Aneuploidy and Chromosome 9p Loss on Tumor Immune Microenvironment and Immune Checkpoint Inhibitor Efficacy in NSCLC

Authors: Alessi, Joao V., Wang, Xinan, Elkrief, Arielle, Ricciuti, Biagio, Li, Yvonne Y., Gupta, Hersh, Spurr, Liam F., Rizvi, Hira, Luo, Jia, Pecci, Federica, Lamberti, Giuseppe, Recondo, Gonzalo, Venkatraman, Deepti, Di Federico, Alessandro, Gandhi, Malini M., Vaz, Victor R., Nishino, Mizuki, Sholl, Lynette M., Cherniack, Andrew D., Ladanyi, Marc, Price, Adam, Richards, Allison L., Donoghue, Mark, Lindsay, James, Sharma, Bijaya, Turner, Madison M., Pfaff, Kathleen L., Felt, Kristen D., Rodig, Scott J., Lin, Xihong, Meyerson, Matthew L., Johnson, Bruce E., Christiani, David C., Schoenfeld, Adam J., Awad, Mark M.

Source: In Journal of Thoracic Oncology November 2023 18(11):1524-1537

Analysis of recurrence in lung adenocarcinoma with spread through air spaces

Authors: Khalil, Hassan A., Shi, Weiwei, Mazzola, Emanuele, Lee, Daniel Nahum, Norton-Hughes, Emily, Dolan, Daniel, Corman, Samantha, White, Abby, Sholl, Lynette M., Swanson, Scott J.

Source: In The Journal of Thoracic and Cardiovascular Surgery November 2023 166(5):1317-1328

Recurrent Tumor Suppressor Alterations in Primary Pericardial Mesothelioma

Authors: Schaefer, Inga-Marie, Mariño-Enríquez, Adrian, Hammer, Mark M., Padera, Robert F., Sholl, Lynette M.

Source: In Modern Pathology September 2023 36(9)

Molecular Correlates of Aggressive Behavior and Biological Progression in Testicular Sertoli Cell Tumors

Authors: Rizzo, Natalie M., Sholl, Lynette M., Kao, Chia-Sui, Cornejo, Kristine M., Sangoi, Ankur R., Hirsch, Michelle S., Collins, Katrina, Gordetsky, Jennifer B., Reyes Curcio, Fabiola A., Fletcher, Christopher D.M., Ulbright, Thomas M., Acosta, Andres M.

Source: In Modern Pathology July 2023 36(7)