Comparative effectiveness of subcutaneous sarilumab 200 mg biweekly, subcutaneous Tocilizumab 162 mg biweekly, and intravenous Tocilizumab 8 mg/kg every 4 weeks in patients with rheumatoid arthritis: a prospective cohort study

Authors: Akira Onishi, Masao Tanaka, Takayuki Fujii, Koichi Murata, Kosaku Murakami, Motomu Hashimoto, Ryu Watanabe, Yuji Nozaki, Chisato Ashida, Wataru Yamamoto, Hirotaka Yamada, Sho Sendo, Kosuke Ebina, Hidehiko Makino, Yonsu Son, Yumiko Wada, Kenichiro Hata, Shuichi Matsuda, Akio Morinobu

Source: Arthritis Research & Therapy, Vol 27, Iss 1, Pp 1-11 (2025)

Subject Terms: Rheumatoid arthritis, Antirheumatic agents, Interleukin-6 inhibitors, Tocilizumab, Sarilumab, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/fc8310747e0347119acb51116c294e72

Impact of dysregulated microbiota-derived C18 polyunsaturated fatty acid metabolites on arthritis severity in mice with collagen-induced arthritis

Authors: Katsuhiko Yoneda, Sho Sendo, Takaichi Okano, Hidenori Shimizu, Hirotaka Yamada, Keisuke Nishimura, Yo Ueda, Jun Saegusa

Source: Frontiers in Immunology, Vol 15 (2025)

Subject Terms: metabolome, rheumatoid arthritis, 16S rRNA, collagen-induced arthritis, polyunsaturated fatty acids, gut microbiota-derived metabolites, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1444892/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/82b8ccfadbd246bb84435ad64bd73ef1

Myeloid-derived suppressor cell-derived osteoclasts with bone resorption capacity in the joints of arthritic SKG mice

Authors: Yoshikazu Fujikawa, Sho Sendo, Alfonso del Peral Fanjul, Hirotaka Yamada, Kenichi Uto, Yuzuru Yamamoto, Takumi Nagamoto, Akio Morinobu, Jun Saegusa

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: MDSCs, SKG mice, osteoclastogenesis, arthritis, microarray, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1168323/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/d1a23e26cd514993bbab3db12f2d7450

Effect of resolvin D5 on T cell differentiation and osteoclastogenesis analyzed by lipid mediator profiling in the experimental arthritis

Authors: Hirotaka Yamada, Jun Saegusa, Sho Sendo, Yo Ueda, Takaichi Okano, Masakazu Shinohara, Akio Morinobu

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/bbfcd4187e6d49eaa9de0ede60c1c736

Soluble guanylate cyclase stimulator reduced the gastrointestinal fibrosis in bleomycin-induced mouse model of systemic sclerosis

Authors: Yuzuru Yamamoto, Takaichi Okano, Hirotaka Yamada, Kengo Akashi, Sho Sendo, Yo Ueda, Akio Morinobu, Jun Saegusa

Source: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)

Subject Terms: Systemic sclerosis, Gastrointestinal fibrosis, Soluble guanylate cyclase stimulator, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/62301b154fe244268a832ff99e4400db

Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice

Authors: Sho Sendo, Jun Saegusa, Hirotaka Yamada, Keisuke Nishimura, Akio Morinobu

Source: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-9 (2019)

Subject Terms: Rheumatoid arthritis, Interstitial lung disease, Tofacitinib, Myeloid-derived suppressor cells, Th17 cells, Dendritic cells, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-019-1963-2; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/67afb73308b7478faf86666f663c1d58

Myeloid-derived suppressor cells in non-neoplastic inflamed organs

Authors: Sho Sendo, Jun Saegusa, Akio Morinobu

Source: Inflammation and Regeneration, Vol 38, Iss 1, Pp 1-11 (2018)

Subject Terms: MDSC, Inflammation, T cell, Myeloid cell, Organ, Plasticity, Pathology, RB1-214

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s41232-018-0076-7; https://doaj.org/toc/1880-8190

Access URL: https://doaj.org/article/0c37f7ff08054a03a6c29b600d30c66d

Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis

Authors: Soshi Takahashi, Jun Saegusa, Sho Sendo, Takaichi Okano, Kengo Akashi, Yasuhiro Irino, Akio Morinobu

Source: Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-10 (2017)

Subject Terms: Fibroblasts, Glutaminolysis, Glutamine, Metabolomics, Rheumatoid arthritis, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-017-1283-3; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/7595bc5ee28c4ad1936221cc563f70ae

Treatment with an Anti-CX3CL1 Antibody Suppresses M1 Macrophage Infiltration in Interstitial Lung Disease in SKG Mice

Authors: Satoshi Mizutani, Junko Nishio, Kanoh Kondo, Kaori Motomura, Zento Yamada, Shotaro Masuoka, Soichi Yamada, Sei Muraoka, Naoto Ishii, Yoshikazu Kuboi, Sho Sendo, Tetuo Mikami, Toshio Imai, Toshihiro Nanki

Source: Pharmaceuticals, Vol 14, Iss 5, p 474 (2021)

Subject Terms: rheumatoid arthritis, interstitial lung diseases, CX3CL1/fractalkine, CX3CR1, M1 macrophage, M2 macrophage, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/14/5/474; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/c21147631aaf4f7da94e6a4dd6707d8b

Subarachnoid Hemorrhaging with Multiple Cerebral Artery Stenoses after Initiating Remission Induction Therapy for Eosinophilic Granulomatosis with Polyangiitis.

Authors: Haruka Yasuba, Hirotaka Yamada, Masaya Togo, Kento Matoba, Eriko Yamamoto Kashihara, Keisuke Nishimura, Sho Sendo, Yo Ueda, Jun Saegusa

Source: Internal Medicine; 2024, Vol. 63 Issue 24, p3389-3394, 6p

Myeloid-derived suppressor cellderived osteoclasts with bone resorption capacity in the joints of arthritic SKG mice.

Authors: Yoshikazu Fujikawa, Sho Sendo, Fanjul, Alfonso del Peral, Hirotaka Yamada, Kenichi Uto, Yuzuru Yamamoto, Takumi Nagamoto, Akio Morinobu, Jun Saegusa

Source: Frontiers in Immunology; 2024, p1-14, 14p

Subject Terms: BONE resorption, MYELOID-derived suppressor cells, BONE marrow, JOINT pain, OSTEOCLASTS, T cell differentiation

IgG4-related disease manifesting as pericarditis with elevated adenosine deaminase and IL-10 levels in pericardial fluid.

Authors: Sho Sendo¹, Jun Saegusa¹, Yukiko Morinaga², Fumi Kawakami², Yoshinori Kogata¹, Goichi Kageyama¹, Akio Morinobu¹ morinobu@med.kobe-u.ac.jp

Source: Modern Rheumatology. 2017, Vol. 27 Issue 5, p894-897. 4p.

Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice.

Authors: Kengo Akashi, Jun Saegusa, Sho Sendo, Keisuke Nishimura, Takuya Okano, Keiko Yagi, Masashi Yanagisawa, Noriaki Emoto, Akio Morinobu

Source: Arthritis Research & Therapy; 5/21/2016, Vol. 18, p1-9, 9p