The Immune Inductive Role of Hepatic Arterial Infusion Chemotherapy Prior to Atezolizumab Plus Bevacizumab Combination Therapy in Hepatocellular Carcinoma

Authors: Suzuki, Hiroyuki, Sakai, Miwa, Iwamoto, Hideki, Shimose, Shigeo, Niizeki, Takashi, Nakano, Masahito, Shirono, Tomotake, Noda, Yu, Moriyama, Etsuko, Kuromatsu, Ryoko, Koga, Hironori, Kawaguchi, Takumi

Source: In Gastro Hep Advances 2024 3(4):506-509

The impact of curative conversion therapy aimed at a cancer‐free state in patients with hepatocellular carcinoma treated with atezolizumab plus bevacizumab

Authors: Shimose, Shigeo, Iwamoto, Hideki, Shirono, Tomotake, Tanaka, Masatoshi, Niizeki, Takashi, Kajiwara, Masahiko, Itano, Satoshi, Yano, Yoichi, Matsugaki, Satoru, Moriyama, Etsuko, Noda, Yu, Nakano, Masahito, Kuromatsu, Ryoko, Koga, Hironori, Kawaguchi, Takumi

Source: Cancer medicine. 12(11):12325-12335

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195120064.0x000001&indx=1&recIds=ETOCvdc_100195120064.0x000001

Telephone follow‐up contributes to improving adherence and treatment duration in patients with hepatocellular carcinoma treated with lenvatinib

Authors: Tsumura, Sayo, Shimose, Shigeo, Niizeki, Takashi, Kuboyama, Eri, Iwamoto, Hideki, Tanaka, Masatoshi, Moriyama, Etusko, Shirono, Tomotake, Takaki, Kota, Noda, Yu, Nakano, Masahito, Inoue, Mitsutoshi, Tsustumi, Kazuki, Kuromatsu, Ryoko, Koga, Hironori, Higuchi, Kyoko, Kawaguchi, Takumi

Source: Journal of gastroenterology and hepatology. 38(7):1140-1147

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188336006.0x000001&indx=1&recIds=ETOCvdc_100188336006.0x000001

Tumor‐derived insulin‐like growth factor‐binding protein‐1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors

Authors: Suzuki, Hiroyuki, Iwamoto, Hideki, Seki, Takahiro, Nakamura, Toru, Masuda, Atsutaka, Sakaue, Takahiko, Tanaka, Toshimitsu, Imamura, Yasuko, Niizeki, Takashi, Nakano, Masahito, Shimose, Shigeo, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Sakai, Miwa, Morita, Kazutoyo, Nakayama, Masamichi, Yoshizumi, Tomoharu, Kuromatsu, Ryoko, Yano, Hirohisa, Cao, Yihai, Koga, Hironori, Torimura, Takuji

Source: Cancer communications. 43(4):415-434

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181639561.0x000001&indx=1&recIds=ETOCvdc_100181639561.0x000001

The beneficial impact of metabolic dysfunction‐associated fatty liver disease on lenvatinib treatment in patients with non‐viral hepatocellular carcinoma

Authors: Shimose, Shigeo, Hiraoka, Atsushi, Casadei‐Gardini, Andrea, Tsutsumi, Tsubasa, Nakano, Dan, Iwamoto, Hideki, Tada, Fujimasa, Rimini, Margherita, Tanaka, Masatoshi, Torimura, Takuji, Suga, Hideya, Ohama, Hideko, Burgio, Valentina, Niizeki, Takashi, Moriyama, Etsuko, Suzuki, Hiroyuki, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Nakano, Masahito, Kuromatsu, Ryoko, Koga, Hironori, Kawaguchi, Takumi

Source: Hepatology research. 53(2):104-115

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173068049.0x000001&indx=1&recIds=ETOCvdc_100173068049.0x000001

Significance of ramucirumab following atezolizumab plus bevacizumab therapy for hepatocellular carcinoma using real‐world data

Authors: Shimose, Shigeo, Sugimoto, Rie, Hiraoka, Atsushi, Tanaka, Masatoshi, Iwamoto, Hideki, Tanaka, Yuki, Tada, Fujimasa, Ohama, Hideko, Niizeki, Takashi, Shirono, Tomotake, Moriyama, Etsuko, Noda, Yu, Kamachi, Naoki, Nakano, Masahito, Kuromatsu, Ryoko, Koga, Hironori, Kawaguchi, Takumi

Source: Hepatology research. 53(2):116-126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173068095.0x000001&indx=1&recIds=ETOCvdc_100173068095.0x000001

Durable complete response is achieved by balloon‐occluded transcatheter arterial chemoembolization for hepatocellular carcinoma

Authors: Shirono, Tomotake, Iwamoto, Hideki, Niizeki, Takashi, Shimose, Shigeo, Kajiwara, Akira, Suzuki, Hiroyuki, Kamachi, Naoki, Noda, Yu, Okamura, Shusuke, Nakano, Masahito, Kuromatsu, Ryoko, Murotani, Kenta, Koga, Hironori, Torimura, Takuji

Source: Hepatology communications. 6(9):2594-2604

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190649555.0x000001&indx=1&recIds=ETOCvdc_100190649555.0x000001

Lenvatinib versus sorafenib as second-line therapy following progression on atezolizumab–bevacizumab in patients with unresectable hepatocellular carcinoma: a multicenter retrospective study from Korea and Japan.

Authors: Cheon, Jaekyung, Shimose, Shigeo, Kim, Hyung-Don, Niizeki, Takashi, Ryu, Min-Hee, Shirono, Tomotake, Ryoo, Baek-Yeol, Iwamoto, Hideki, Yoo, Changhoon

Source: Journal of Cancer Research & Clinical Oncology; Feb2025, Vol. 151 Issue 2, p1-7, 7p

DNA Methylation in Noncancerous Liver Tissues as Biomarker for Multicentric Occurrence of Hepatitis C Virus–Related Hepatocellular Carcinoma

Authors: Suzuki, Hiroyuki, Iwamoto, Hideki, Yamamoto, Ken, Tsukaguchi, Mai, Nakamura, Toru, Masuda, Atsutaka, Sakaue, Takahiko, Tanaka, Toshimitsu, Niizeki, Takashi, Okamura, Shusuke, Shimose, Shigeo, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Kuromatsu, Ryoko, Hisaka, Toru, Yano, Hirohisa, Koga, Hironori, Torimura, Takuji

Source: In Gastro Hep Advances 2022 1(4):555-562

Efficacy and tolerability of Sorafenib plus metronomic chemotherapy S-1 for advanced hepatocellular carcinoma in preclinical and clinical assessments

Authors: Suzuki, Hiroyuki, Iwamoto, Hideki, Nakano, Masahito, Nakamura, Toru, Masuda, Atsutaka, Sakaue, Takahiko, Tanaka, Toshimitsu, Nakano, Dan, Kuromatsu, Ryoko, Niizeki, Takashi, Okamura, Shusuke, Shimose, Shigeo, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Yano, Hirohisa, Kawaguchi, Atsushi, Koga, Hironori, Torimura, Takuji

Source: In Translational Oncology November 2021 14(11)

First‐line sorafenib sequential therapy and liver disease etiology for unresectable hepatocellular carcinoma using inverse probability weighting: A multicenter retrospective study

Authors: Shimose, Shigeo, Hiraoka, Atsushi, Nakano, Masahito, Iwamoto, Hideki, Tanaka, Masatoshi, Tanaka, Takaaki, Noguchi, Kazunori, Aino, Hajime, Ogata, Kei, Kajiwara, Masahiko, Itano, Satoshi, Yokokura, Yoshinori, Yamaguchi, Taizo, Kawano, Hiroshi, Matsukuma, Norito, Suga, Hideya, Niizeki, Takashi, Shirono, Tomotake, Noda, Yu, Kamachi, Naoki, Okamura, Shusuke, Kawaguchi, Takumi, Koga, Hironori, Torimura, Takuji

Source: Cancer medicine. 10(23):8530-8541

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135760352.0x000001&indx=1&recIds=ETOCvdc_100135760352.0x000001

Multimolecular-Targeted Agents for Intermediate-Stage Hepatocellular Carcinoma Influence Time to Stage Progression and Overall Survival

Authors: Shimose, Shigeo, Iwamoto, Hideki, Tanaka, Masatoshi, Niizeki, Takashi, Shirono, Tomotake, Kajiwara, Akira, Noda, Yu, Kamachi, Naoki, Okamura, Shusuke, Nakano, Masahito, Kuromatsu, Ryoko, Kawaguchi, Takumi, Koga, Hironori, Torimura, Takuji

Source: Oncology. 99(12):756-765

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134972528.0x000001&indx=1&recIds=ETOCvdc_100134972528.0x000001

Efficacy of Atezolizumab Plus Bevacizumab–Transcatheter Arterial Chemoembolization Sequential Therapy for Patients with Intermediate-Stage Hepatocellular Carcinoma.

Authors: Moriyama, Etsuko, Shimose, Shigeo, Niizeki, Takashi, Iwamoto, Hideki, Tanaka, Masatoshi, Shirono, Tomotake, Noda, Yu, Nakano, Masahito, Kuromatsu, Ryoko, Koga, Hironori, Kawaguchi, Takumi

Source: Current Oncology; Oct2024, Vol. 31 Issue 10, p5821-5831, 11p

Subject Terms: OVERALL survival, PROGRESSION-free survival, HEPATOCELLULAR carcinoma, CHEMOEMBOLIZATION, ATEZOLIZUMAB

Increased Arterio-Portal Shunt Formation after Drug-Eluting Beads TACE for Hepatocellular Carcinoma

Authors: Shimose, Shigeo, Iwamoto, Hideki, Tanaka, Masatoshi, Niizeki, Takashi, Shirono, Tomotake, Nakano, Masahito, Okamura, Syusuke, Noda, Yu, Kamachi, Naoki, Sakai, Miwa, Suzuki, Hiroyuki, Nomiyama, Mika, Kuromatsu, Ryoko, Koga, Hironori, Torimura, Takuji

Source: Oncology. 98(8):558-565

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108777926.0x000001&indx=1&recIds=ETOCvdc_100108777926.0x000001

Alpha-fetoprotein and des-gamma-carboxy prothrombin can predict the objective response of patients with hepatocellular carcinoma receiving durvalumab plus tremelimumab therapy.

Authors: Saeki, Issei, Shimose, Shigeo, Tomonari, Tetsu, Ito, Takanori, Tani, Joji, Takeuchi, Yasuto, Yoshioka, Naoki, Naito, Takehito, Takeuchi, Mamiko, Kakizaki, Satoru, Hatanaka, Takeshi, Sasaki, Kyo, Yasunaka, Tetsuya, Sakata, Masahiro, Iwamoto, Hideki, Itano, Satoshi, Shirono, Tomotake, Tanabe, Norikazu, Yamamoto, Takafumi, Kanayama, Yuki

Source: PLoS ONE; 9/25/2024, Vol. 19 Issue 9, p1-13, 13p

Subject Terms: TUMOR markers, ODDS ratio, PROGRESSION-free survival, HEPATOCELLULAR carcinoma, PROTHROMBIN, ALPHA fetoproteins

Prognostic impact of transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation in patients with unresectable hepatocellular carcinoma: Comparison with TACE alone using decision‐tree analysis after propensity score matching

Authors: Shimose, Shigeo, Tanaka, Masatoshi, Iwamoto, Hideki, Niizeki, Takashi, Shirono, Tomotake, Aino, Hajime, Noda, Yu, Kamachi, Naoki, Okamura, Shusuke, Nakano, Masahito, Kuromatsu, Ryoko, Kawaguchi, Takumi, Kawaguchi, Atsushi, Koga, Hironori, Yokokura, Yoshinori, Torimura, Takuji

Source: Hepatology research. 49(8):919-928

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087676243.0x000001&indx=1&recIds=ETOCvdc_100087676243.0x000001

Dose and Location of Irradiation Determine Survival for Patients with Hepatocellular Carcinoma with Macrovascular Invasion in External Beam Radiation Therapy

Authors: Iwamoto, Hideki, Nomiyama, Mika, Niizeki, Takashi, Shimose, Shigeo, Shirono, Tomotake, Nakano, Masahito, Satani, Manabu, Okamura, Syusuke, Noda, Yu, Kamachi, Naoki, Sakai, Miwa, Suzuki, Hiroyuki, Kuromatsu, Ryoko, Ogo, Etsuyo, Abe, Toshi, Tanaka, Masatoshi, Koga, Hironori, Torimura, Takuji

Source: Oncology. 96(4):192-199

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084722829.0x000001&indx=1&recIds=ETOCvdc_100084722829.0x000001

Epirubicin is More Effective than Miriplatin in Balloon-Occluded Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma

Authors: Shirono, Tomotake, Iwamoto, Hideki, Niizeki, Takashi, Shimose, Shigeo, Nakano, Masahito, Satani, Manabu, Okamura, Syuusuke, Noda, Yu, Kamachi, Naoki, Kuromatsu, Ryoko, Sakai, Miwa, Nomiyama, Mika, Kuwano, Toru, Tanaka, Masatoshi, Koga, Hironori, Torimura, Takuji

Source: Oncology. 96(2):79-86

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084722725.0x000001&indx=1&recIds=ETOCvdc_100084722725.0x000001

Evaluating the therapeutic effect of lenvatinib against advanced hepatocellular carcinoma by measuring blood flow changes using contrast‐enhanced ultrasound

Authors: Kamachi, Naoki, Nakano, Masahito, Okamura, Shusuke, Niizeki, Takashi, Iwamoto, Hideki, Shimose, Shigeo, Shirono, Tomotake, Noda, Yu, Kuromatsu, Ryoko, Koga, Hironori, Torimura, Takuji

Source: Cancer reports. 5(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141127202.0x000001&indx=1&recIds=ETOCvdc_100141127202.0x000001

Usefulness of a novel transarterial chemoinfusion plus external‐beam radiation therapy for advanced hepatocellular carcinoma with tumor thrombi in the inferior vena cava and right atrium: Case study

Authors: Shirono, Tomotake, Koga, Hironori, Niizeki, Takashi, Nagamatsu, Hiroaki, Iwamoto, Hideki, Shimose, Shigeo, Nakano, Masahito, Okamura, Shusuke, Noda, Yu, Kamachi, Naoki, Kuromatsu, Ryoko, Ogo, Etsuyo, Torimura, Takuji

Source: Cancer reports. 5(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157760205.0x000001&indx=1&recIds=ETOCvdc_100157760205.0x000001