Infliximab Inhibits Colitis Associated Cancer in Model Mice by Downregulating Genes Associated with Mast Cells and Decreasing Their Accumulation

Authors: Dan-Yang Wang, Shinobu Ohnuma, Hideyuki Suzuki, Masaharu Ishida, Kentaro Ishii, Takashi Hirosawa, Tomoaki Hirashima, Megumi Murakami, Minoru Kobayashi, Katsuyoshi Kudoh, Sho Haneda, Hiroaki Musha, Takeshi Naitoh, Michiaki Unno

Source: Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 2895-2907 (2023)

Subject Terms: inflammatory bowel disease, Crohn’s disease, ulcerative colitis, colitis-associated cancer, TNF-α, anti TNF-α antibody, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/45/4/189; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/e2e2accfa2b0434380dec5347ea7f766

Characteristics of anal canal cancer in Japan

Authors: Kazutaka Yamada, Yasumitsu Saiki, Koji Komori, Akio Shiomi, Masashi Ueno, Masaaki Ito, Koya Hida, Seiichiro Yamamoto, Manabu Shiozawa, Soichiro Ishihara, Yukihide Kanemitsu, Hideki Ueno, Tatsuya Kinjo, Kotaro Maeda, Junichiro Kawamura, Fumihiko Fujita, Keiichi Takahashi, Tsunekazu Mizushima, Yasuhiro Shimada, Shin Sasaki, Eiji Sunami, Fumio Ishida, Keiji Hirata, Shinobu Ohnuma, Kimihiko Funahashi, Jun Watanabe, Yusuke Kinugasa, Shigeki Yamaguchi, Yojiro Hashiguchi, Masataka Ikeda, Takeshi Sudo, Yoshito Komatsu, Keiji Koda, Kazuhiro Sakamoto, Masazumi Okajima, Hideyuki Ishida, Yuichi Hisamatsu, Taiki Masuda, Shinichiro Mori, Kazuhito Minami, Seiji Hasegawa, Shungo Endo, Akinori Iwashita, Madoka Hamada, Yoichi Ajioka, Koichiro Usuku, Tokunori Ikeda, Kenichi Sugihara

Source: Cancer Medicine, Vol 11, Iss 14, Pp 2735-2743 (2022)

Subject Terms: abdominoperineal resection, anal canal cancer, chemoradiotherapy, human papillomavirus, squamous cell carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/8d46538318c1400a871ddb740e9e60b2

Evaluation of a 55-gene classifier as a prognostic biomarker for adjuvant chemotherapy in stage III colon cancer patients

Authors: Eiji Oki, Eiji Shinto, Mototsugu Shimokawa, Shigeki Yamaguchi, Megumi Ishiguro, Seiji Hasegawa, Yasumasa Takii, Hideyuki Ishida, Tetsuya Kusumoto, Masaru Morita, Naohiro Tomita, Manabu Shiozawa, Masafumi Tanaka, Heita Ozawa, Yojiro Hashiguchi, Shinobu Ohnuma, Sachiyo Tada, Tomoko Matsushima, Kazuo Hase

Source: BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)

Subject Terms: Colon cancer, Predictive, Adjuvant chemotherapy, Oxaliplatin, Subtyping, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/c2ec5d1caa444a408e73dce04b5f3429

Antimesenteric cutback end‐to‐end isoperistaltic anastomosis (Sasaki‐Watanabe anastomosis) for Crohn's disease: Novel surgical technique and early results of surgical anastomotic recurrence

Authors: Kazuhiro Watanabe, Iwao Sasaki, Atsushi Kohyama, Hideyuki Suzuki, Minoru Kobayashi, Taiki Kajiwara, Hideaki Karasawa, Shinobu Ohnuma, Takashi Kamei, Michiaki Unno

Source: Annals of Gastroenterological Surgery, Vol 5, Iss 4, Pp 528-537 (2021)

Subject Terms: antimesenteric cutback end‐to‐end isoperistaltic anastomosis, Crohn's disease, Sasaki‐W anastomosis, Sasaki‐Watanabe anastomosis, surgical technique, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/2475-0328

Access URL: https://doaj.org/article/8dfc5e15bebd4f6aa415d272a8ceaa12

Laparoscopic right hemicolectomy for an ascending colon cancer patient with an implantable left ventricular assist device: a case report

Authors: Taiki Kajiwara, Takeshi Naitoh, Yusuke Suzuki, Atsushi Kohyama, Hideaki Karasawa, Hideyuki Suzuki, Masatoshi Akiyama, Yoshikatsu Saiki, Kazuhiro Watanabe, Shinobu Ohnuma, Takashi Kamei, Michiaki Unno

Source: Surgical Case Reports, Vol 6, Iss 1, Pp 1-6 (2020)

Subject Terms: Left ventricular assist device, Colon cancer, Laparoscopic surgery, Surgery, RD1-811

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40792-020-01064-9; https://doaj.org/toc/2198-7793

Access URL: https://doaj.org/article/41cacf0e32744a979e6ff1dd3a3e9761

microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer

Authors: Hidekazu Takahashi, Masanobu Takahashi, Shinobu Ohnuma, Michiaki Unno, Yuki Yoshino, Kota Ouchi, Shin Takahashi, Yasuhide Yamada, Hideki Shimodaira, Chikashi Ishioka

Source: BMC Cancer, Vol 17, Iss 1, Pp 1-14 (2017)

Subject Terms: Colorectal cancer, BRAF, miRNA, miR-193a-3p, Anti-EGFR therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-017-3739-x; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/4750580dc7dd4571bcd3e593767d7fd4

Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer.

Authors: Takashi Hirosawa, Masaharu Ishida, Kentaro Ishii, Keigo Kanehara, Katsuyoshi Kudo, Shinobu Ohnuma, Takashi Kamei, Fuyuhiko Motoi, Takeshi Naitoh, Florin M Selaru, Michiaki Unno

Source: PLoS ONE, Vol 13, Iss 11, p e0206643 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6218052?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/624abb02f39541ad9b6a5aef4da9d81e

The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter.

Authors: Pei-Rong Ding, Amit K Tiwari, Shinobu Ohnuma, Jeferson W K K Lee, Xin An, Chun-Ling Dai, Qi-Si Lu, Satyakam Singh, Dong-Hua Yang, Tanaji T Talele, Suresh V Ambudkar, Zhe-Sheng Chen

Source: PLoS ONE, Vol 6, Iss 4, p e19329 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3084276?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cb95b23e897c4dfcb741737a73a9522f

Diagnosis and Treatment of Perianal Disease in Crohn's Disease.

Authors: Kazuhiro Watanabe¹, Shinobu Ohnuma¹, Michiaki Unno¹

Source: Nihon Daicho Komonbyo Gakkai Zasshi. Oct2024, Vol. 77 Issue 10, p533-541. 9p.

Subject Terms: *CROHN'S disease, *STEM cell treatment, *ANAL diseases, *ANAL fistula, *THERAPEUTICS

Esophageal Intramural Pseudodiverticulosis Diagnosed by Combining Esophagogastroduodenoscopy, Esophagography, and High-resolution Manometry.

Authors: Atsushi Kunimitsu, Naoto Ujiie, Chiaki Sato, Yusuke Taniyama, Hiroshi Okamoto, Toshiaki Fukutomi, Yohei Ozawa, Shinobu Ohnuma, Michiaki Unno, Takashi Kamei

Source: Internal Medicine; 2023, Vol. 62 Issue 10, p1495-1499, 5p

MDR1 Synonymous Polymorphisms Alter Transporter Specificity and Protein Stability in a Stable Epithelial Monolayer.

Authors: King Leung Fung¹, Pan, James¹, Shinobu Ohnuma¹, Lund, Paul E.¹, Pixley, Jessica N.¹, Kimchi-Sarfaty, Chava², Ambudkar, Suresh V.¹, Gottesman, Michael M.¹ mgottesman@nih.gov

Source: Cancer Research. 1/15/2014, Vol. 74 Issue 2, p598-608. 11p.

Subject Terms: *GLYCOPROTEINS, *GENETIC polymorphism research, *RHODAMINES, *RECOMBINANT DNA research, *RECOMBINANT drugs