Therapeutic gene correction for Lesch-Nyhan syndrome using CRISPR-mediated base and prime editing

Authors: Jang, Gayoung, Shin, Ha Rim, Do, Hyo-Sang, Kweon, Jiyeon, Hwang, Soojin, Kim, Soyoung, Heo, Sun Hee, Kim, Yongsub, Lee, Beom Hee

Source: Molecular therapy.Nucleic acids. 31:586-595

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185950179.0x000001&indx=1&recIds=ETOCvdc_100185950179.0x000001

Engineered prime editors with PAM flexibility

Authors: Kweon, Jiyeon, Yoon, Jung-Ki, Jang, An-Hee, Shin, Ha Rim, See, Ji-Eun, Jang, Gayoung, Kim, Jong-Il, Kim, Yongsub

Source: In Molecular Therapy 2 June 2021 29(6):2001-2007

Gene Manipulation Using Fusion Guide RNAs for Cas9 and Cas12a

Authors: Shin, Ha Rim, Kweon, Jiyeon, Kim, Yongsub

Source: Methods in molecular biology. 2162:185-196

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624736988&indx=1&recIds=ETOCRN624736988

A CRISPR-based base-editing screen for the functional assessment of BRCA1 variants

Authors: Kweon, Jiyeon, Jang, An-Hee, Shin, Ha Rim, See, Ji-Eun, Lee, Woochang, Lee, Jong Won, Chang, Suhwan, Kim, Kyunggon, Kim, Yongsub

Source: Oncogene. 39(1):30-35

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193644962.0x000001&indx=1&recIds=ETOCvdc_100193644962.0x000001

Effect of parasitic infection on muscular function of dystrophin gene (Dmd) deficient mouse.

Authors: Shin, Ha Rim, Ko, Eun-Ji, Kang, Yun-Jeong, Yu, Hak-Sun, Ock, Mee Sun, Cha, Hee-Jae

Source: Genes & Genomics; Feb2023, Vol. 45 Issue 2, p183-190, 8p

AWP1 Restrains the Aggressive Behavior of Breast Cancer Cells Induced by TNF-α.

Authors: Kim, Eun-Young, Kim, Ji-Eun, Choi, Bongkun, Kweon, Jiyeon, Park, Si-On, Lee, Hee-Seop, Lee, Eun-Jin, Oh, Soyoon, Shin, Ha Rim, Choi, Hyuksu, Kim, Yongsub, Chang, Eun-Ju

Source: Frontiers in Oncology; 3/18/2021, Vol. 11, pN.PAG-N.PAG, 11p

Subject Terms: CANCER cells, CANCER invasiveness, BREAST cancer, CANCER cell proliferation, REACTIVE oxygen species

Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing.

Authors: Shin, Ha Rim, See, Ji-Eun, Kweon, Jiyeon, Kim, Heon Seok, Sung, Gi-Jun, Park, Sojung, Jang, An-Hee, Jang, Gayoung, Choi, Kyung‐Chul, Kim, Inki, Kim, Jin-Soo, Kim, Yongsub

Source: Nucleic Acids Research; 2/26/2021, Vol. 49 Issue 4, p2390-2399, 10p

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