Single-cell analysis of menstrual endometrial tissues defines phenotypes associated with endometriosis.

Authors: Shih, Andrew J.¹ (AUTHOR), Adelson, Robert P.¹ (AUTHOR), Vashistha, Himanshu¹ (AUTHOR), Khalili, Houman¹ (AUTHOR), Nayyar, Ashima¹ (AUTHOR), Puran, Radha¹ (AUTHOR), Herrera, Rixsi¹ (AUTHOR), Chatterjee, Prodyot K.¹ (AUTHOR), Lee, Annette T.^1,2 (AUTHOR), Truskinovsky, Alexander M.^2,3 (AUTHOR), Elmaliki, Kristine¹ (AUTHOR), DeFranco, Margaret¹ (AUTHOR), Metz, Christine N.^1,2 (AUTHOR) cmetz@northwell.edu, Gregersen, Peter K.^1,2 (AUTHOR) pgregers@northwell.edu

Source: BMC Medicine. 9/15/2022, Vol. 20 Issue 1, p1-16. 16p.

Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis.

Authors: Delenko, Julia, Xue, Xiangying, Chatterjee, Prodyot K, Hyman, Nathaniel, Shih, Andrew J, Adelson, Robert P, Safaric Tepes, Polona, Gregersen, Peter K, Metz, Christine N

Source: Reproductive Biology & Endocrinology; 8/8/2024, Vol. 22 Issue 1, p1-18, 18p

Subject Terms: HUMAN embryo transfer, STROMAL cells, PELVIS, PULMONARY fibrosis, QUERCETIN, PELVIC pain

Complete miRNA-15/16 loss in mice promotes hematopoietic progenitor expansion and a myeloid-biased hyperproliferative state.

Authors: N. g., Anita, Lovat, Francesca, Shih, Andrew J., Yuhong Ma, Pekarsky, Yuri, DiCaro, Frank, Crichton, Lita, Sharma, Esha, Xiao Jie Yan, Daqian Sun, Tengfei Song, Yong-Rui Zou, Will, Britta, Croce, Carlo M., Chiorazzi, Nicholas

Source: Proceedings of the National Academy of Sciences of the United States of America; 10/24/2023, Vol. 120 Issue 43, p1-10, 19p

Subject Terms: CHRONIC myeloid leukemia, ACUTE myeloid leukemia, B cell lymphoma, HEMATOPOIETIC stem cells, CHRONIC lymphocytic leukemia

Phenotypic and functional characteristics of murine CD11c+ B cells which is suppressed by metformin.

Authors: De Oleo, Ivan Ramirez, Kim, Vera, Atisha-Fregoso, Yemil, Shih, Andrew J., Kyungwoo Lee, Diamond, Betty, Sun Jung Kim

Source: Frontiers in Immunology; 2023, p01-15, 15p

Subject Terms: B cells, T cell receptors, ANTIGEN presentation, T cells, CELL populations

Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq.

Authors: Shih, Andrew J.¹ ashih@northwell.edu, Menzin, Andrew², Whyte, Jill², Lovecchio, John², Liew, Anthony¹, Khalili, Houman¹, Bhuiya, Tawfiqul², Gregersen, Peter K.^1,2, Lee, Annette T.^1,2

Source: PLoS ONE. 11/1/2018, Vol. 13 Issue 11, p1-17. 17p.

Subject Terms: *OVARIAN cancer, *RNA sequencing, *CANCER genetics, *EPITHELIAL cells, *LEUKOCYTES, *CELL populations

Inherited cancer predisposing mutations in patients with therapy‐related myeloid neoplasms.

Authors: Shih, Andrew J.¹ (AUTHOR), Jun, Tomi² (AUTHOR), Skol, Andrew D.³ (AUTHOR), Bao, Riyue^4,5 (AUTHOR), Huang, Lei⁶ (AUTHOR), Vora, Sapana³ (AUTHOR), McNerney, Megan E.^3,7 (AUTHOR), Hungate, Eric A.³ (AUTHOR), Le Beau, Michelle M.⁸ (AUTHOR), Larson, Richard A.⁸ (AUTHOR), Elliott, Aaron⁹ (AUTHOR), Lu, Hsiao‐Mei⁹ (AUTHOR), Huether, Robert⁹ (AUTHOR), Hernandez, Felicia⁹ (AUTHOR), Stölzel, Friedrich¹⁰ (AUTHOR), Allan, James M.¹¹ (AUTHOR), Onel, Kenan^2,12 (AUTHOR) ken.onel@sema4.com

Source: British Journal of Haematology. Feb2023, Vol. 200 Issue 4, p489-493. 5p.

Subject Terms: *TUMORS, *GENETIC testing, *GERM cells

Proteomic and Single-Cell Transcriptomic Dissection of Human Plasmacytoid Dendritic Cell Response to Influenza Virus.

Authors: Ghanem, Mustafa H., Shih, Andrew J., Khalili, Houman, Werth, Emily G., Chakrabarty, Jayanta K., Brown, Lewis M., Simpfendorfer, Kim R., Gregersen, Peter K.

Source: Frontiers in Immunology; 3/23/2022, Vol. 13, p1-14, 14p

Subject Terms: INFLUENZA A virus, INFLUENZA viruses, DENDRITIC cells, TYPE I interferons, PROTEOMICS

Maternal oxytocin administration modulates gene expression in the brains of perinatal mice.

Authors: Hsieh, Frances F., Korsunsky, Ilya, Shih, Andrew J., Moss, Matthew A., Chatterjee, Prodyot K., Deshpande, Jaai, Xue, Xiangying, Madankumar, Swati, Kumar, Gopal, Rochelson, Burton, Metz, Christine N.

Source: Journal of Perinatal Medicine; Feb2022, Vol. 50 Issue 2, p207-218, 12p

Subject Terms: RNA analysis, DNA analysis, OXYTOCIN, BRAIN, BIOLOGICAL models, ANIMAL experimentation, GENE expression, UTERUS, POLYMERASE chain reaction, MICE, FETUS

Investigations into SCAMP5, a candidate lupus risk gene expressed in plasmacytoid dendritic cells.

Authors: Ghanem, Mustafa H., Shih, Andrew J., Vashistha, Himanshu, Coke, Latanya N., Wentian Li, Sun Jung Kim, Simpfendorfer, Kim R., Gregersen, Peter K.

Source: Lupus Science & Medicine; May2021, Vol. 8 Issue 1, p1-9, 9p

Prognostic Molecular Signatures for Metastatic Potential in Clinically Low-Risk Stage I and II Clear Cell Renal Cell Carcinomas.

Authors: Shih, Andrew J., Murphy, Neal, Kozel, Zachary, Shah, Paras, Yaskiv, Oksana, Khalili, Houman, Liew, Anthony, Kavoussi, Louis, Hall, Simon, Vira, Manish, Zhu, Xin-Hua, Lee, Annette T.

Source: Frontiers in Oncology; 8/11/2020, Vol. 10, pN.PAG-N.PAG, 9p

Subject Terms: RENAL cell carcinoma, MOLECULAR pathology, AGGRESSIVE driving, KIDNEY development, METASTATIC breast cancer, OXIDATIVE phosphorylation

Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases.

Authors: Shih, Andrew J.¹ shihaj@seas.upenn.edu, Telesco, Shannon E.¹ shannone@seas.upenn.edu, Radhakrishnan, Ravi¹ rradhak@seas.upenn.edu

Source: Cancers. 2011, Vol. 3 Issue 1, p1195-1231. 37p. 3 Diagrams, 4 Charts, 2 Graphs.

Subject Terms: *ANTIBODY diversity, *MOLECULAR diagnosis of cancer, *CELL proliferation, *LUNG cancer, *PROGNOSIS, *PROTEIN-tyrosine kinases

Correction: Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq.

Authors: Shih, Andrew J., Menzin, Andrew, Whyte, Jill, Lovecchio, John, Liew, Anthony, Khalili, Houman, Bhuiya, Tawfiqul, Gregersen, Peter K., Lee, Annette T.

Source: PLoS ONE. 12/4/2018, Vol. 13 Issue 12, p1-1. 1p.

Subject Terms: *OVARIAN cancer, *GYNECOLOGIC cancer

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Conserved Hydrophobic and Hydrophilic Bond Interaction Networks in ErbB Family Kinases

Authors: Shih, Andrew J., Telesco, Shannon E., Choi, Sung Hee, Lemmon, Mark A., Radhakrishnan, Ravi

Source: In Biophysical Journal January 2010 98(3) Supplement 1:445a-445a

Antigen-presenting aged neutrophils induce CD4⁺ T cells to exacerbate inflammation in sepsis.

Authors: Hui Jin, Aziz, Monowar, Murao, Atsushi, Kobritz, Molly, Shih, Andrew J., Adelson, Robert P., Brenner, Max, Wang, Ping

Source: Journal of Clinical Investigation. 7/17/2023, Vol. 133 Issue 14, p1-15. 16p.

Subjects: T cells, NEUTROPHILS, SEPSIS, BONE marrow, RNA-binding proteins, T cell receptors

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