Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice

Authors: Kinashi, Yusuke, Tanaka, Keisuke, Kimura, Shunsuke, Hirota, Masato, Komiyama, Seiga, Shindo, Tomoko, Hashiguchi, Akinori, Takahashi, Daisuke, Shibata, Shinsuke, Karaki, Shin-Ichiro, Ohno, Hiroshi, Hase, Koji

Source: In eBioMedicine August 2024 106

Impaired Glycosylation of Gastric Mucins Drives Gastric Tumorigenesis and Serves as a Novel Therapeutic Target

Authors: Arai, Junya, Hayakawa, Yoku, Tateno, Hiroaki, Murakami, Keita, Hayashi, Takeru, Hata, Masahiro, Matsushita, Yuki, Kinoshita, Hiroto, Abe, Sohei, Kurokawa, Ken, Oya, Yukiko, Tsuboi, Mayo, Ihara, Sozaburo, Niikura, Ryota, Suzuki, Nobumi, Iwata, Yusuke, Shiokawa, Toshiro, Shiomi, Chihiro, Uekura, Chie, Yamamoto, Keisuke, Fujiwara, Hiroaki, Kawamura, Satoshi, Nakagawa, Hayato, Mizuno, Seiya, Kudo, Takashi, Takahashi, Satoru, Ushiku, Tetsuo, Hirata, Yoshihiro, Fujii, Chifumi, Nakayama, Jun, Shibata, Shinsuke, Woods, Susan, Worthley, Daniel L., Hatakeyama, Masanori, Wang, Timothy C., Fujishiro, Mitsuhiro

Source: In Gastroenterology August 2024 167(3):505-521

Human-induced pluripotent stem cell-derived neural stem/progenitor cell ex vivo gene therapy with synaptic organizer CPTX for spinal cord injury

Authors: Saijo, Yusuke, Nagoshi, Narihito, Kawai, Momotaro, Kitagawa, Takahiro, Suematsu, Yu, Ozaki, Masahiro, Shinozaki, Munehisa, Kohyama, Jun, Shibata, Shinsuke, Takeuchi, Kosei, Nakamura, Masaya, Yuzaki, Michisuke, Okano, Hideyuki

Source: In Stem Cell Reports 12 March 2024 19(3):383-398

In utero Exposure to Valproic Acid throughout Pregnancy Causes Phenotypes of Autism in Offspring Mice

Authors: Mitsuhashi, Takayuki, Hattori, Satoko, Fujimura, Kimino, Shibata, Shinsuke, Miyakawa, Tsuyoshi, Takahashi, Takao

Source: Developmental neuroscience. 45(5):223-233

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196470315.0x000001&indx=1&recIds=ETOCvdc_100196470315.0x000001

Maternal Immune Activation by Polyinosinic-Polycytidylic Acid Exposure Causes Cerebral Cortical Dysgenesis through Dysregulated Cell Cycle Kinetics of Neural Stem/Progenitor Cells

Authors: Sasaki, Marie, Mitsuhashi, Takayuki, Goto, Fumiko, Shibata, Shinsuke, Kubo, Ken-ichiro, Oku, Shinju, Owashi, Akihiro, Takahashi, Takao

Source: Developmental neuroscience. 45(3):115-125

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185355928.0x000001&indx=1&recIds=ETOCvdc_100185355928.0x000001

Escherichia coli‐derived outer‐membrane vesicles induce immune activation and progression of cirrhosis in mice and humans

Authors: Natsui, Kazuki, Tsuchiya, Atsunori, Imamiya, Risa, Osada‐Oka, Mayuko, Ishii, Yui, Koseki, Yohei, Takeda, Nobutaka, Tomiyoshi, Kei, Yamazaki, Fusako, Yoshida, Yuki, Ohashi, Riuko, Ling, Yiwei, Ueda, Koji, Moritoki, Nobuko, Sato, Kazuhiro, Nakajima, Takahiro, Hasegawa, Yoshinori, Okuda, Shujiro, Shibata, Shinsuke, Terai, Shuji

Source: Liver international. 43(5):1126-1140

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182487727.0x000001&indx=1&recIds=ETOCvdc_100182487727.0x000001

Heart-derived collagen promotes maturation of engineered heart tissue

Authors: Tani, Hidenori, Kobayashi, Eiji, Yagi, Shinomi, Tanaka, Keisuke, Kameda-Haga, Kotaro, Shibata, Shinsuke, Moritoki, Nobuko, Takatsuna, Kaworu, Moriwaki, Taijun, Sekine, Otoya, Umei, Tomohiko C, Morita, Yuika, Soma, Yusuke, Kishino, Yoshikazu, Kanazawa, Hideaki, Fujita, Jun, Hattori, Shunji, Fukuda, Keiichi, Tohyama, Shugo

Source: In Biomaterials August 2023 299

The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy

Authors: Fukuda, Tomoyuki, Furukawa, Kentaro, Maruyama, Tatsuro, Yamashita, Shun-ichi, Noshiro, Daisuke, Song, Chihong, Ogasawara, Yuta, Okuyama, Kentaro, Alam, Jahangir Md, Hayatsu, Manabu, Saigusa, Tetsu, Inoue, Keiichi, Ikeda, Kazuho, Takai, Akira, Chen, Lin, Lahiri, Vikramjit, Okada, Yasushi, Shibata, Shinsuke, Murata, Kazuyoshi, Klionsky, Daniel J., Noda, Nobuo N., Kanki, Tomotake

Source: In Molecular Cell 15 June 2023 83(12):2045-2058

Microenvironmental modulation in tandem with human stem cell transplantation enhances functional recovery after chronic complete spinal cord injury

Authors: Hashimoto, Shogo, Nagoshi, Narihito, Shinozaki, Munehisa, Nakanishi, Katsuyuki, Suematsu, Yu, Shibata, Takahiro, Kawai, Momotaro, Kitagawa, Takahiro, Ago, Kentaro, Kamata, Yasuhiro, Yasutake, Kaori, Koya, Ikuko, Ando, Yoshinari, Minoda, Aki, Shindo, Tomoko, Shibata, Shinsuke, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

Source: In Biomaterials April 2023 295

D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease

Authors: Umeda, Satoko, Sujino, Tomohisa, Miyamoto, Kentaro, Yoshimatsu, Yusuke, Harada, Yosuke, Nishiyama, Keita, Aoto, Yoshimasa, Adachi, Keika, Hayashi, Naoki, Amafuji, Kimiko, Moritoki, Nobuko, Shibata, Shinsuke, Sasaki, Nobuo, Mita, Masashi, Tanemoto, Shun, Ono, Keiko, Mikami, Yohei, Sasabe, Jumpei, Takabayashi, Kaoru, Hosoe, Naoki, Suzuki, Toshihiko, Sato, Toshiro, Atarashi, Koji, Teratani, Toshiaki, Ogata, Haruhiko, Nakamoto, Nobuhiro, Shiomi, Daisuke, Ashida, Hiroshi, Kanai, Takanori

Source: In Cellular and Molecular Gastroenterology and Hepatology 2023 16(6):1011-1031

Do Pharmacological Treatments Act in Collaboration with Rehabilitation in Spinal Cord Injury Treatment? A Review of Preclinical Studies.

Authors: Tashiro, Syoichi^1,2 (AUTHOR) s-tashiro@keio.jp, Shibata, Shinsuke³ (AUTHOR), Nagoshi, Narihito⁴ (AUTHOR), Zhang, Liang² (AUTHOR), Yamada, Shin² (AUTHOR), Tsuji, Tetsuya¹ (AUTHOR), Nakamura, Masaya⁴ (AUTHOR), Okano, Hideyuki⁵ (AUTHOR)

Source: Cells (2073-4409). Mar2024, Vol. 13 Issue 5, p412. 28p.

Subject Terms: *SPINAL cord injuries, *DRUG therapy, *MEDICAL rehabilitation, *REHABILITATION, *SCARS, *ELECTROSTATIC discharges

Chitinase-like protein 3: A novel niche factor for mouse neural stem cells

Authors: Namiki, Jun, Suzuki, Sayuri, Shibata, Shinsuke, Kubota, Yoshiaki, Kaneko, Naoko, Yoshida, Kenji, Yamaguchi, Ryo, Matsuzaki, Yumi, Masuda, Takeshi, Ishihama, Yasushi, Sawamoto, Kazunobu, Okano, Hideyuki

Source: In Stem Cell Reports 13 December 2022 17(12):2704-2717

Eyelid blood vessel and meibomian gland changes in a sclerodermatous chronic GVHD mouse model

Authors: Yang, Fan, Hayashi, Isami, Sato, Shinri, Saijo-Ban, Yumiko, Yamane, Mio, Fukui, Masaki, Shimizu, Eisuke, He, Jingliang, Shibata, Shinsuke, Mukai, Shin, Asai, Kazuki, Ogawa, Mamoru, Lan, Yuqing, Zeng, Qingyan, Hirakata, Akito, Tsubota, Kazuo, Ogawa, Yoko

Source: In The Ocular Surface October 2022 26:328-341

Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury

Authors: Kitagawa, Takahiro, Nagoshi, Narihito, Kamata, Yasuhiro, Kawai, Momotaro, Ago, Kentaro, Kajikawa, Keita, Shibata, Reo, Sato, Yuta, Imaizumi, Kent, Shindo, Tomoko, Shinozaki, Munehisa, Kohyama, Jun, Shibata, Shinsuke, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

Source: Stem cell reports. 17(1):127-142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153362319.0x000001&indx=1&recIds=ETOCvdc_100153362319.0x000001

In Vivo Imaging Analysis of an Inner Ear Drug Delivery in Mice: Comparison of Inner Ear Drug Concentrations Over Time

Authors: Kanzaki, Sho, Shibata, Shinsuke, Nakamura, Masaya, Ozaki, Masahiro, Okano, Hideyuki

Source: Methods in molecular biology. 2524:327-332

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629813110&indx=1&recIds=ETOCRN629813110

Glycosaminoglycans promote osteogenesis from human induced pluripotent stem cells via neural crest induction

Authors: Yanagisawa, Takuma, Ouchi, Takehito, Shibata, Shinsuke, Negishi, Tomofumi, Okano, Hideyuki

Source: Biochemical and biophysical research communications. 603:49-56

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158225139.0x000001&indx=1&recIds=ETOCvdc_100158225139.0x000001

Administration of C5a Receptor Antagonist Improves the Efficacy of Human Induced Pluripotent Stem Cell–Derived Neural Stem/Progenitor Cell Transplantation in the Acute Phase of Spinal Cord Injury

Authors: Shibata, Reo, Nagoshi, Narihito, Kajikawa, Keita, Ito, Shuhei, Shibata, Shinsuke, Shindo, Tomoko, Khazaei, Mohamad, Nori, Satoshi, Kohyama, Jun, Fehlings, Michael G., Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

Source: Journal of neurotrauma. 39(9/10):667-682

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148850171.0x000001&indx=1&recIds=ETOCvdc_100148850171.0x000001

Mice with Heterozygous Deletion of Exon 3 in the Gh Gene Demonstrate Growth Retardation Caused by Reduced Ghrhr mRNA.

Authors: Ariyasu, Daisuke, Higa, Daisuke, Tokudome, Ryo, Yonemori, Takumi, Shimada, Hayate, Shibata, Shinsuke, Araki, Kimi

Source: International Journal of Molecular Sciences; Feb2025, Vol. 26 Issue 3, p1061, 14p

Subject Terms: GROWTH hormone releasing factor, GENE expression, GROWTH disorders, MEMBRANE proteins, SOMATOTROPIN, SOMATOTROPIN receptors

Peripheral nerve regeneration using a bioresorbable silk fibroin-based artificial nerve conduit fabricated via a novel freeze–thaw process.

Authors: Matsuo, Tomoki, Kimura, Hiroo, Nishijima, Takayuki, Kiyota, Yasuhiro, Suzuki, Taku, Nagoshi, Narihito, Shibata, Shinsuke, Shindo, Tomoko, Moritoki, Nobuko, Sasaki, Makoto, Noguchi, Sarara, Tamada, Yasushi, Nakamura, Masaya, Iwamoto, Takuji

Source: Scientific Reports; 1/31/2025, Vol. 15 Issue 1, p1-15, 15p

Effect of Alaska pollock-gelatin sheet on repair strength and regeneration of nerve.

Authors: Tsujisaka, Ryosuke, Suzuki, Taku, Shibata, Shinsuke, Iwamoto, Takuji, Taguchi, Tetsushi, Nakamura, Masaya

Source: Journal of Hand Surgery (17531934); Jan2025, Vol. 50 Issue 1, p76-84, 9p

Subject Terms: FIBRIN tissue adhesive, CLINICAL medicine, SCIATIC nerve, SUTURES, FIBRIN

Geographic Terms: ALASKA