Beyond mutations: Accounting for quantitative changes in the analysis of protein evolution

Authors: Xiaoyong Wu, Shesh N. Rai, Georg F. Weber

Source: Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2637-2647 (2024)

Subject Terms: Protein sequence, Phylogenetic tree, Wavelet analysis, Matrix distance, Heat map, Clustering, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037024002186; https://doaj.org/toc/2001-0370

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Carnosine supplementation improves cognitive outcomes in younger participants of the NEAT trial

Authors: Timothy E. O'Toole, Alok R. Amraotkar, Hong Gao, Clara G. Sears, Shesh N. Rai, Mathias Basner, Aruni Bhatnagar

Source: Neurotherapeutics, Vol 22, Iss 2, Pp e00541- (2025)

Subject Terms: Carnosine, Cognition, Clinical trial, Neurology. Diseases of the nervous system, RC346-429

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Relation: http://www.sciencedirect.com/science/article/pii/S1878747925000194; https://doaj.org/toc/1878-7479

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Evaluation of supplementary carnosine accumulation and distribution: an initial analysis of participants in the Nucleophilic Defense Against PM Toxicity (NEAT) clinical trial

Authors: Shahid P. Baba, Alok R. Amraotkar, David Hoetker, Hong Gao, Daniel Gomes, Jingjing Zhao, Michael F. Wempe, Peter J. Rice, Andrew P. DeFilippis, Shesh N. Rai, C. Arden Pope, Aruni Bhatnagar, Timothy E. O’Toole

Source: Amino Acids, Vol 56, Iss 1, Pp 1-15 (2024)

Subject Terms: Carnosine, Carnosine propanol, Carnosine propanal, Measurement, Biochemistry, QD415-436, Biology (General), QH301-705.5

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Relation: https://doaj.org/toc/1438-2199

Access URL: https://doaj.org/article/9373a884d0d247a780738f3bc613583e

Detection of COVID-19 by quantitative analysis of carbonyl compounds in exhaled breath

Authors: Zhenzhen Xie, James D. Morris, Jianmin Pan, Elizabeth A. Cooke, Saurin R. Sutaria, Dawn Balcom, Subathra Marimuthu, Leslie W. Parrish, Holly Aliesky, Justin J. Huang, Shesh N. Rai, Forest W. Arnold, Jiapeng Huang, Michael H. Nantz, Xiao-An Fu

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: COVID-19 detection, Breath analysis, Carbonyl compounds, UHPLC-MS, Microreactor, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5dcc2bc18c644b838fddf60dc2ea9cea

Estimation of foot-and-mouth disease virus sero-prevalence rates using novel computational approach for the susceptible bovine population in India during the period 2008–2021

Authors: Samarendra Das, Soumen Pal, Sagar Sangam Rautaray, Jajati K. Mohapatra, Saravanan Subramaniam, Manoranjan Rout, Shesh N. Rai, Rabindra Prasad Singh

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

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Predicting the Effect of miRNA on Gene Regulation to Foster Translational Multi-Omics Research—A Review on the Role of Super-Enhancers

Authors: Sarmistha Das, Shesh N. Rai

Source: Non-Coding RNA, Vol 10, Iss 4, p 45 (2024)

Subject Terms: super-enhancer, miRNA, gene regulatory network, transcription factor, multi-omics, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.mdpi.com/2311-553X/10/4/45; https://doaj.org/toc/2311-553X

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Metallomics in pulmonary arterial hypertension patients

Authors: Karim El‐Kersh, C. Danielle Hopkins, Xiaoyong Wu, Shesh N. Rai, Matthew C. Cave, M. Ryan Smith, Young‐Mi Go, Dean P. Jones, Lu Cai, Jiapeng Huang

Source: Pulmonary Circulation, Vol 13, Iss 1, Pp n/a-n/a (2023)

Subject Terms: chromium, copper, metal, pulmonary hypertension, silver, Diseases of the circulatory (Cardiovascular) system, RC666-701, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8940

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Proteomics and metabolic phenotyping define principal roles for the aryl hydrocarbon receptor in mouse liver

Authors: Jian Jin, Banrida Wahlang, Monika Thapa, Kimberly Z. Head, Josiah E. Hardesty, Sudhir Srivastava, Michael L. Merchant, Shesh N. Rai, Russell A. Prough, Matthew C. Cave

Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3806-3819 (2021)

Subject Terms: AHR, Endocrine disruption, Environmental liver disease, Nonalcoholic fatty liver disease, Perilipin-2, Pheromones, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S2211383521004068; https://doaj.org/toc/2211-3835

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Microbiome data analysis with applications to pre-clinical studies using QIIME2: Statistical considerations

Authors: Shesh N. Rai, Chen Qian, Jianmin Pan, Jayesh P. Rai, Ming Song, Juhi Bagaitkar, Michael Merchant, Matthew Cave, Nejat K. Egilmez, Craig J. McClain

Source: Genes and Diseases, Vol 8, Iss 2, Pp 215-223 (2021)

Subject Terms: 16S rRNA gene, Alpha diversity, ANOVA, Beta diversity, Bioinformatics, Microbiome data, Medicine (General), R5-920, Genetics, QH426-470

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Relation: http://www.sciencedirect.com/science/article/pii/S2352304219301217; https://doaj.org/toc/2352-3042

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Statistical design of Phase II/III clinical trials for testing therapeutic interventions in COVID-19 patients

Authors: Shesh N. Rai, Chen Qian, Jianmin Pan, Anand Seth, Deo Kumar Srivastava, Aruni Bhatnagar

Source: BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-16 (2020)

Subject Terms: Composite outcomes, COVID-19, Efficacy, Hospitalization, Interim analysis, Intubation, Medicine (General), R5-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12874-020-01101-z; https://doaj.org/toc/1471-2288

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Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells

Authors: Lindsey R. Conroy, Pawel Lorkiewicz, Liqing He, Xinmin Yin, Xiang Zhang, Shesh N. Rai, Brian F. Clem

Source: Cancer Cell International, Vol 20, Iss 1, Pp 1-12 (2020)

Subject Terms: RB, Palbociclib, Metabolism, Glutaminolysis, PPP, Lung cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

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Relation: http://link.springer.com/article/10.1186/s12935-020-01357-x; https://doaj.org/toc/1475-2867

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Predictors of thrombosis in patients treated with bevacizumab

Authors: Jessica Sparks, Xiaoyong Wu, Mika Kessans Knable, Shesh N. Rai, Vivek Sharma

Source: Thrombosis Update, Vol 6, Iss , Pp 100095- (2022)

Subject Terms: Bevacizumab, Thrombosis, Proteinuria, Hypertension, Hyperlipidemia, Diseases of the circulatory (Cardiovascular) system, RC666-701

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Relation: http://www.sciencedirect.com/science/article/pii/S266657272100064X; https://doaj.org/toc/2666-5727

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Multigroup prediction in lung cancer patients and comparative controls using signature of volatile organic compounds in breath samples

Authors: Shesh N. Rai, Samarendra Das, Jianmin Pan, Dwijesh C. Mishra, Xiao-An Fu

Source: PLoS ONE, Vol 17, Iss 11 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710764/?tool=EBI; https://doaj.org/toc/1932-6203

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Plasma level of antimony correlates with pulmonary arterial hypertension severity

Authors: Karim El-Kersh, C. Danielle Hopkins, Xiaoyong Wu, Shesh N. Rai, Lu Cai, Jiapeng Huang

Source: Current Research in Toxicology, Vol 3, Iss , Pp 100080- (2022)

Subject Terms: PAH, RV dysfunction, Metal toxicity, Antimony, Non-essential metals, Toxicology. Poisons, RA1190-1270

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Relation: http://www.sciencedirect.com/science/article/pii/S2666027X22000172; https://doaj.org/toc/2666-027X

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Pre-Existing Comorbidities Diminish the Likelihood of Seropositivity after SARS-CoV-2 Vaccination

Authors: Alok R. Amraotkar, Adrienne M. Bushau-Sprinkle, Rachel J. Keith, Krystal T. Hamorsky, Kenneth E. Palmer, Hong Gao, Shesh N. Rai, Aruni Bhatnagar

Source: Vaccines, Vol 10, Iss 8, p 1363 (2022)

Subject Terms: SARS-CoV-2 antibody, antibody response, serology, serostatus, comorbidity, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/10/8/1363; https://doaj.org/toc/2076-393X

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Differential Expression Analysis of Single-Cell RNA-Seq Data: Current Statistical Approaches and Outstanding Challenges

Authors: Samarendra Das, Anil Rai, Shesh N. Rai

Source: Entropy, Vol 24, Iss 7, p 995 (2022)

Subject Terms: scRNA-seq, differential expression analysis, classification, statistical approaches, challenges, Science, Astrophysics, QB460-466, Physics, QC1-999

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Relation: https://www.mdpi.com/1099-4300/24/7/995; https://doaj.org/toc/1099-4300

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Statistical methods for analysis of single-cell RNA-sequencing data

Authors: Samarendra Das, Ph.D., Shesh N. Rai, Ph.D.

Source: MethodsX, Vol 8, Iss , Pp 101580- (2021)

Subject Terms: Zero inflated negative binomial model, Molecular capture model, Observed UMI count, True UMI count, Mean, Zero Inflation, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2215016121003708; https://doaj.org/toc/2215-0161

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Circulating plasma microRNAs in colorectal neoplasia: A pilot study in assessing response to therapy

Authors: Stephen J O'Brien, Uri Netz, Jacob Hallion, Campbell Bishop, Vincent Stephen, James Burton, Mason Paas, Kayla Feagins, Jianmin Pan, Shesh N. Rai, Susan Galandiuk

Source: Translational Oncology, Vol 14, Iss 1, Pp 100962- (2021)

Subject Terms: Colorectal cancer, Colorectal advanced adenoma, microRNA, Surveillance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: http://www.sciencedirect.com/science/article/pii/S193652332030454X; https://doaj.org/toc/1936-5233

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Prevalence, patterns, and predictors of diarrhea: a spatial-temporal comprehensive evaluation in India

Authors: Nilima, Asha Kamath, Karthik Shetty, B. Unnikrishnan, Siddharth Kaushik, Shesh N. Rai

Source: BMC Public Health, Vol 18, Iss 1, Pp 1-10 (2018)

Subject Terms: Hotspot, Spatial regression, Spatial lag-model, Spatial error model, India, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12889-018-6213-z; https://doaj.org/toc/1471-2458

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Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

Authors: Dominique Z. Jones, M. Lee Schmidt, Suman Suman, Katharine R. Hobbing, Shirish S. Barve, Leila Gobejishvili, Guy Brock, Carolyn M. Klinge, Shesh N. Rai, Jong Park, Geoffrey J. Clark, Rajesh Agarwal, LaCreis R. Kidd

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-16 (2018)

Subject Terms: microRNA, Prostate cancer, miR-186, Serum, AKAP12, β-catenin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: http://link.springer.com/article/10.1186/s12885-018-4258-0; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/bfc4991aa79b45b7bd513dceb81c33ea