Redundant pathways for removal of defective RNA polymerase II complexes at a promoter-proximal pause checkpoint

Authors: Blears, Daniel ^{1, 2, 5}, Lou, Jiangman ^{1, 5}, Fong, Nova ³, Mitter, Richard ⁴, Sheridan, Ryan M. ³, He, Dandan ¹, Dirac-Svejstrup, A. Barbara ¹, Bentley, David ³, Svejstrup, Jesper Q. ^{1, 6, ∗}

Source: In Molecular Cell 19 December 2024 84(24):4790-4807

The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model

Authors: Fong, Nova, Sheridan, Ryan M., Ramachandran, Srinivas, Bentley, David L.

Source: In Molecular Cell 6 October 2022 82(19):3632-3645

Precise gene models using long-read sequencing reveal a unique poly(A) signal in Giardia lamblia

Authors: Bilodeau, Danielle Y., Sheridan, Ryan M., Balan, Balu, Jex, Aaron R., Rissland, Olivia S.

Source: RNA. 28(5):668-682

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629197393&indx=1&recIds=ETOCRN629197393

Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a “Sitting Duck Torpedo” Mechanism

Authors: Cortazar, Michael A., Sheridan, Ryan M., Erickson, Benjamin, Fong, Nova, Glover-Cutter, Kira, Brannan, Kristopher, Bentley, David L.

Source: In Molecular Cell 19 December 2019 76(6):896-908

Inactivation of GSK3β by Ser389phosphorylation prevents thymocyte necroptosis and impacts Tcrrepertoire diversity

Authors: Valença-Pereira, Felipe, Sheridan, Ryan M., Riemondy, Kent A., Thornton, Tina, Fang, Qian, Barret, Brad, Paludo, Gabriela, Thompson, Claudia, Collins, Patrick, Santiago, Mario, Oltz, Eugene, Rincon, Mercedes

Source: Cell Death and Differentiation; 20250101, Issue: Preprints p1-19, 19p

Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling

Authors: Summers, Megan E., Richmond, Bradley W., Menon, Swapna, Sheridan, Ryan M., Kropski, Jonathan A., Majka, Sarah A., Taketo, M. Mark, Bastarache, Julie A., West, James D., De Langhe, Stijn, Geraghty, Patrick, Klemm, Dwight J., Chu, Hong Wei, Friedman, Rachel S., Tao, Yuankai K., Foronjy, Robert F., Majka, Susan M.

Source: FASEB journal. 34(8):10267-10285

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122653804.0x000001&indx=1&recIds=ETOCvdc_100122653804.0x000001

Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5′ Pause Release, Termination, and Transcription Elongation Rate

Authors: Sheridan, Ryan M., Fong, Nova, D’Alessandro, Angelo, Bentley, David L.

Source: In Molecular Cell 3 January 2019 73(1):107-118

RNA Pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD Phosphorylation, and Transcriptional Direction

Authors: Fong, Nova, Saldi, Tassa, Sheridan, Ryan M., Cortazar, Michael A., Bentley, David L.

Source: In Molecular Cell 18 May 2017 66(4):546-557

Dynamic turnover of paused Pol II complexes at human promoters

Authors: Erickson, Benjamin, Sheridan, Ryan M., Cortazar, Michael, Bentley, David L.

Source: Genes & development. 32(17/18):1215-1225

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN617296005&indx=1&recIds=ETOCRN617296005

Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing

Authors: Saldi, Tassa, Cortazar, Michael A., Sheridan, Ryan M., Bentley, David L.

Source: In Journal of Molecular Biology 19 June 2016 428(12):2623-2635

Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition

Authors: Fong, Nova, Brannan, Kristopher, Erickson, Benjamin, Kim, Hyunmin, Cortazar, Michael A., Sheridan, Ryan M., Nguyen, Tram, Karp, Shai, Bentley, David L.

Source: In Molecular Cell 15 October 2015 60(2):256-267

MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination

Authors: Carpentier, Kathryn S, Sheridan, Ryan M, Lucas, Cormac J, Davenport, Bennett J, Li, Frances S, Lucas, Erin D, McCarthy, Mary K, Reynoso, Glennys V, May, Nicholas A, Tamburini, Beth A J, Hesselberth, Jay R, Hickman, Heather D, Morrison, Thomas E

Source: EMBO journal. 40(22)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135573888.0x000001&indx=1&recIds=ETOCvdc_100135573888.0x000001

Selectable one-step PCR-mediated integration of a degron for rapid depletion of endogenous human proteins

Authors: Sheridan, Ryan M., Bentley, David L.

Source: Biotechniques. 60(2):69-74

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124637946.0x000001&indx=1&recIds=ETOCvdc_100124637946.0x000001

Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies.

Authors: Peterson, Jacob N., Boackle, Susan A., Taitano, Sophina H., Sang, Allison, Lang, Julie, Kelly, Margot, Rahkola, Jeremy T., Miranda, Anjelica M., Sheridan, Ryan M., Thurman, Joshua M., Rao, V. Koneti, Torres, Raul M., Pelanda, Roberta

Source: Frontiers in Immunology; 2/4/2022, Vol. 13, p1-15, 15p

Subject Terms: B cells, B cell differentiation, AUTOANTIBODIES, GERMINAL centers, SYSTEMIC lupus erythematosus

MARCO⁺ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination.

Authors: Carpentier, Kathryn S¹ (AUTHOR), Sheridan, Ryan M² (AUTHOR), Lucas, Cormac J¹ (AUTHOR), Davenport, Bennett J¹ (AUTHOR), Li, Frances S¹ (AUTHOR), Lucas, Erin D¹ (AUTHOR), McCarthy, Mary K¹ (AUTHOR), Reynoso, Glennys V³ (AUTHOR), May, Nicholas A¹ (AUTHOR), Tamburini, Beth A J^1,4 (AUTHOR), Hesselberth, Jay R^2,5 (AUTHOR), Hickman, Heather D³ (AUTHOR), Morrison, Thomas E¹ (AUTHOR) thomas.morrison@cuanschutz.edu

Source: EMBO Journal. 11/15/2021, Vol. 40 Issue 22, p1-19. 19p.

Subject Terms: *KUPFFER cells, *VIREMIA, *LIVER cells, *ALPHAVIRUSES, *VIRAL transmission, *ENDOTHELIAL cells

Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node.

Authors: Walsh, Shannon M.¹, Sheridan, Ryan M.², Lucas, Erin D.^3,4, Doan, Thu A.^3,5, Ware, Brian C.^3,4, Schafer, Johnathon⁵, Rui Fu², Burchill, Matthew A.⁵, Hesselberth, Jay R.^1,2, Jiron Tamburini, Beth Ann^3,4,5 beth.tamburini@cuanschutz.edu

Source: eLife. 5/12/2021, p1-29. 29p.

Subject Terms: *LYMPH nodes, *ANTIGENS, *ANTIGEN presentation, *ENDOTHELIAL cells

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The SON RNA splicing factor is required for intracellular trafficking structures that promote centriole assembly and ciliogenesis

Authors: Stemm-Wolf, Alexander J., O'Toole, Eileen T., Sheridan, Ryan M., Morgan, Jacob T., Pearson, Chad G.

Source: Molecular Biology of the Cell; 20210101, Issue: Preprints