Enhancer transcription profiling reveals an enhancer RNA-driven ferroptosis and new therapeutic opportunities in prostate cancer

Authors: Sheng Ma, Zixian Wang, Zezhong Xiong, Yue Ge, Meng-Yao Xu, Junbiao Zhang, Yuzheng Peng, Qin Zhang, Jiaxue Sun, Zirui Xi, Hao Peng, Wenjie Xu, Yanan Wang, Le Li, Chunyu Zhang, Zheng Chao, Baojun Wang, Xu Gao, Xu Zhang, Gong-Hong Wei, Zhihua Wang

Source: Signal Transduction and Targeted Therapy, Vol 10, Iss 1, Pp 1-21 (2025)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/b8c74384ec154a65a63870d434e8ac2e

Polymeric immunogel prevents tumor recurrence and metastasis by dual activation of innate and adaptive immunity

Authors: Guanyu Jin, Hao Liu, Zi Mei, Qionghua Jin, Sheng Ma, Lanqing Wang, Yuanzhen Su, Letian Lv, Zijuan Wang, Huicong Zhou, Mingqiang Li, Zehuan Huang, Xuesi Chen, Shixian Lv

Source: Bioactive Materials, Vol 45, Iss , Pp 102-114 (2025)

Subject Terms: Polymeric drug carriers, Polymeric hydrogels, Biodegradable polymers, Controlled drug release, Tumor recurrence and metastasis, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24004924; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/8d02ceedd9fb45a299b1fb2b07541356

Polydopamine-based nano-protectant for prolonged boar semen preservation by eliminating ROS and regulating protein phosphorylation via D2DR-mediated cAMP/PKA signaling pathway

Authors: Lirui Wang, Manyi Xiong, Jian Zhang, Sisi Li, Sheng Ma, Shengyao Jiang, Yanping Jiang, Xinhong Li

Source: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-19 (2025)

Subject Terms: Semen preservation, Polydopamine nanoparticles, ROS, Protein phosphorylation, D2DR, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/6435c6a4197e4ff2884d7e2e9a96394b

Biomechanics in the tumor microenvironment: from biological functions to potential clinical applications

Authors: Hao Peng, Zheng Chao, Zefeng Wang, Xiaodong Hao, Zirui Xi, Sheng Ma, Xiangdong Guo, Junbiao Zhang, Qiang Zhou, Guanyu Qu, Yuan Gao, Jing Luo, Zhihua Wang, Jing Wang, Le Li

Source: Experimental Hematology & Oncology, Vol 14, Iss 1, Pp 1-24 (2025)

Subject Terms: Tumor microenvironment, Biomechanics, Biomechanical target, Extracellular matrix, Stiffness, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3619

Access URL: https://doaj.org/article/e3c1cbab89e046258fb1fcad821600bb

PDIA2 is associated with the prognosis of prostate cancer, and downregulation of PDIA2 delays the progression of prostate cancer cells

Authors: Qiang Zhou, Yue Ge, Sheng Ma, Zezhong Xiong, Yanan Wang, Le Li, Ling Li, Zheng Chao, Junbiao Zhang, Tengfei Li, Zixi Wu, Yuan Gao, Guanyu Qu, Haoxiao Dong, Zhihua Wang, Wang Jing, Guojun Chen

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: PDIA2, Prostate cancer, Prognosis, Dasatinib, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f59c9d6fbbaa4641abd296ed736d8b7c

Pharmacokinetics, Mass Balance, and Biotransformation of [14C]tinengotinib, A Novel Multi-target Kinase Inhibitor, in Healthy Subjects

Authors: Shumao Ni, Sheng Ma, Yingying Yu, Zhenwen Yu, Yujia Zhu, Xiaofen Sun, Lin Li, Caixia Sun, Hui Wang, Peng Peng, Zheming Gu, Hua Zhang, Frank Wu, Liyan Miao, Jean Fan

Source: Drugs in R&D, Vol 24, Iss 3, Pp 465-476 (2024)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1174-5886; https://doaj.org/toc/1179-6901

Access URL: https://doaj.org/article/a96c91206fe44aeaa8ecec005d3ad7da

Oncogene goosecoid is transcriptionally regulated by E2F1 and correlates with disease progression in prostate cancer

Authors: Yue Ge, Sheng Ma, Qiang Zhou, Zezhong Xiong, Yanan Wang, Le Li, Zheng Chao, Junbiao Zhang, Tengfei Li, Zixi Wu, Yuan Gao, Guanyu Qu, Zirui Xi, Bo Liu, Xi Wu, Zhihua Wang, Yuanyuan Ji

Source: Chinese Medical Journal, Vol 137, Iss 15, Pp 1844-1856 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/CM9.0000000000002865; https://doaj.org/toc/0366-6999; https://doaj.org/toc/2542-5641

Access URL: https://doaj.org/article/c48100758fc84b96ad11cdf70b057804

Estimating the global and regional burden of lower respiratory infections attributable to leading pathogens and the protective effectiveness of immunization programs

Authors: Xiaoran Yu, Huan Wang, Sheng Ma, Wanning Chen, Lin Sun, Zhiyong Zou

Source: International Journal of Infectious Diseases, Vol 149, Iss , Pp 107268- (2024)

Subject Terms: Lower respiratory infection, Pathogen, Global burden, Vaccination, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971224003394; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/fc0c3a28b4b04ed190095b7aaf3dee71

Trojan‐Horse Strategy Targeting the Gut‐Liver Axis Modulates Gut Microbiome and Reshapes Microenvironment for Orthotopic Hepatocellular Carcinoma Therapy

Authors: Haochen Yao, Sheng Ma, Juanjuan Huang, Xinghui Si, Ming Yang, Wantong Song, Guoyue Lv, Guoqing Wang

Source: Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)

Subject Terms: gut microbiota, hepatic inflammation, hepatocellular carcinoma, immunotherapy, oral nanomedicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/77ed13ea08cb43fd86f4092c8206461e

Burden of cardiovascular disease among the Western Pacific region and its association with human resources for health, 1990–2021: a systematic analysis of the Global Burden of Disease Study 2021Research in context

Authors: Huan Wang, Xiaoran Yu, Jianhui Guo, Sheng Ma, Yunfei Liu, Yifei Hu, Jing Li, Yi Song, Zhiyong Zou

Source: The Lancet Regional Health. Western Pacific, Vol 51, Iss , Pp 101195- (2024)

Subject Terms: Cardiovascular disease, Human resources for health, Western Pacific region, Disease burden, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666606524001895; https://doaj.org/toc/2666-6065

Access URL: https://doaj.org/article/61273039f056459eb6179d1c55341846

ATF3 as a response factor to regulate Cd-induced reproductive damage by activating the NRF2/HO-1 ferroptosis pathway

Authors: Sisi Li, Sheng Ma, Lirui Wang, Dian Zhan, Shengyao Jiang, Zhenyang Zhang, Manyi Xiong, Yanping Jiang, Qixian Huang, Jian Zhang, Xinhong Li

Source: Ecotoxicology and Environmental Safety, Vol 285, Iss , Pp 117114- (2024)

Subject Terms: Cadmium toxicity, Ferroptosis, Oxidative stress, Testicular injury, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651324011904; https://doaj.org/toc/0147-6513

Access URL: https://doaj.org/article/2ff1043a4b644500981ee64aba00d13f

Minimally Invasive Injectable Gel for Local Immunotherapy of Liver and Gastric Cancer

Authors: Xinghui Si, Guofeng Ji, Sheng Ma, Zichao Huang, Taiyuan Liu, Zhiyuan Shi, Yu Zhang, Jia Li, Wantong Song, Xuesi Chen

Source: Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)

Subject Terms: cancer immunotherapy, gastric cancer, hydrogels, liver cancer, minimally invasive injection, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/8c53c6c75b1d4946a722d306c93ee26e

Relationship between gut microbiota and the pathogenesis of gestational diabetes mellitus: a systematic review

Authors: Sheng Ma, Yuping Wang, Xiaoxia Ji, Sunjuan Dong, Shengnan Wang, Shuo Zhang, Feiying Deng, Jingxian Chen, Benwei Lin, Barkat Ali Khan, Weiting Liu, Kaijian Hou

Source: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

Subject Terms: gestational diabetes mellitus, gut microbiota, chronic inflammatory state, insulin resistance, pathogenesis, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2024.1364545/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/c8e9fe15d16d4e7dbc280f8d1614b250

Integrating bioinformatic analysis and detailed experiments reveal an EMT‐related biomarker for clear cell renal cell carcinoma

Authors: Yue Ge, Sheng Ma, Junbiao Zhang, Zezhong Xiong, Beining Li, Siquan Ma, Bo Liu, Xiangyang Yao, Zhihua Wang

Source: Cancer Medicine, Vol 12, Iss 18, Pp 19320-19336 (2023)

Subject Terms: biomarker, clear cell renal cell carcinoma, epithelial–mesenchymal transition, OLFML2B, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/3e8368e5407f4731b3b7c3c18a86ddc9

Inventory and Spatial Distribution of Landslides on the Eastern Slope of Gongga Mountain, Southwest China

Authors: Runze Ge, Jian Chen, Sheng Ma, Huarong Tan

Source: Remote Sensing, Vol 16, Iss 18, p 3360 (2024)

Subject Terms: Gongga Mountain, landslide inventory, visual interpretation, spatial distribution, influencing factors, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2072-4292/16/18/3360; https://doaj.org/toc/2072-4292

Access URL: https://doaj.org/article/482faf9ba9ed444887c007f1c08fdc2c

The Alternating Direction Method of Multipliers for Sufficient Dimension Reduction

Authors: Sheng Ma, Qin Jiang, Zaiqiang Ku

Source: Journal of Mathematics, Vol 2024 (2024)

Subject Terms: Mathematics, QA1-939

File Description: electronic resource

Relation: https://doaj.org/toc/2314-4785

Access URL: https://doaj.org/article/22b940da899b4cc9895b18cf1afc5b58

Metabolic classifications of renal cell carcinoma reveal intrinsic connections with clinical and immune characteristics

Authors: Le Li, Zheng Chao, Un Waikeong, Jun Xiao, Yue Ge, Yanan Wang, Zezhong Xiong, Sheng Ma, Zhihua Wang, Zhiquan Hu, Xing Zeng

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)

Subject Terms: Tumor metabolism, RCC, Metabolic classification, Tumor immunity, Prognosis model, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/a304f120d2604ef79e87531b4983fc65

Autophagy and biotransformation affect sorafenib resistance in hepatocellular carcinoma

Authors: Ruiqi Zheng, Shuang Weng, Jianping Xu, Zhuo Li, Yaru Wang, Zulihumaer Aizimuaji, Sheng Ma, Linlin Zheng, Haiyang Li, Wantao Ying, Weiqi Rong, Ting Xiao

Source: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3564-3574 (2023)

Subject Terms: Sorafenib resistance, Autophagy, Biotransformation, Proteomics, HCC, PI3K/AKT/mTOR, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037023002398; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/3329a2098f694384bab273a36625cbbb

Microbe-Derived Antioxidants Protect IPEC-1 Cells from H2O2-Induced Oxidative Stress, Inflammation and Tight Junction Protein Disruption via Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1β Signaling Pathway

Authors: Cheng Shen, Zhen Luo, Sheng Ma, Chengbing Yu, Ting Lai, Shangshang Tang, Hongcai Zhang, Jing Zhang, Weina Xu, Jianxiong Xu

Source: Antioxidants, Vol 13, Iss 5, p 533 (2024)

Subject Terms: microbe-derived antioxidants, oxidative stress, inflammatory response, tight junction proteins, Nrf2/ROS/NLRP3/IL-1β, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/5/533; https://doaj.org/toc/2076-3921

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Targeting Alpha‐Ketoglutarate Disruption Overcomes Immunoevasion and Improves PD‐1 Blockade Immunotherapy in Renal Cell Carcinoma

Authors: Le Li, Xing Zeng, Zheng Chao, Jing Luo, Wei Guan, Qiang Zhang, Yue Ge, Yanan Wang, Zezhong Xiong, Sheng Ma, Qiang Zhou, Junbiao Zhang, Jihua Tian, David Horne, Bertram Yuh, Zhiquan Hu, Gong‐Hong Wei, Baojun Wang, Xu Zhang, Peixiang Lan, Zhihua Wang

Source: Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)

Subject Terms: alpha‐ketoglutarate, B2M, immunoevasion, PD‐1 blockade, renal cell carcinoma, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/407d7273c52643ac8a473ac44a636bd1