Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

Authors: Keshet, Rom, Lee, Joo Sang, Adler, Lital, Iraqi, Muhammed, Ariav, Yarden, Lim, Lisha Qiu Jin, Lerner, Shaul, Rabinovich, Shiran, Oren, Roni, Katzir, Rotem, Weiss Tishler, Hila, Stettner, Noa, Goldman, Omer, Landesman, Hadas, Galai, Sivan, Kuperman, Yael, Kuznetsov, Yuri, Brandis, Alexander, Mehlman, Tevi, Malitsky, Sergey, Itkin, Maxim, Koehler, S. Eleonore, Zhao, Yongmei, Talsania, Keyur, Shen, Tsai-wei, Peled, Nir, Ulitsky, Igor, Porgador, Angel, Ruppin, Eytan, Erez, Ayelet

Source: Nature cancer. 1(9):894-908

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172462850.0x000001&indx=1&recIds=ETOCvdc_100172462850.0x000001

Serum microRNA Profiles and Pathways in Hepatitis B-Associated Hepatocellular Carcinoma: A South African Study.

Authors: Sartorius, Kurt, Sartorius, Benn, Winkler, Cheryl, Chuturgoon, Anil, Shen, Tsai-Wei, Zhao, Yongmei, An, Ping

Source: International Journal of Molecular Sciences; Jan2024, Vol. 25 Issue 2, p975, 26p

Subject Terms: GENE expression, HEPATOCELLULAR carcinoma, MICRORNA, HEPATITIS

Geographic Terms: SUB-Saharan Africa

Structural variant analysis of a cancer reference cell line sample using multiple sequencing technologies.

Authors: Talsania, Keyur, Shen, Tsai-wei, Chen, Xiongfong, Jaeger, Erich, Li, Zhipan, Chen, Zhong, Chen, Wanqiu, Tran, Bao, Kusko, Rebecca, Wang, Limin, Pang, Andy Wing Chun, Yang, Zhaowei, Choudhari, Sulbha, Colgan, Michael, Fang, Li Tai, Carroll, Andrew, Shetty, Jyoti, Kriga, Yuliya, German, Oksana, Smirnova, Tatyana

Source: Genome Biology; 12/13/2022, Vol. 23 Issue 1, p1-33, 33p

The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma.

Authors: Heinrich, Bernd, Gertz, E. Michael, Schäffer, Alejandro A., Craig, Amanda, Ruf, Benjamin, Subramanyam, Varun, McVey, John C., Diggs, Laurence P., Heinrich, Sophia, Rosato, Umberto, Chi Ma, Chunhua Yan, Ying Hu, Yongmei Zhao, Tsai-Wei Shen, Tsai-Wei, Kapoor, Veena, Telford, William, Kleiner, David E., Stovroff, Merril K., Dhani, Harmeet S.

Source: Gut; Jun2022, Vol. 71 Issue 6, p1161-1175, 30p

Subject Terms: INNATE lymphoid cells, TUMOR microenvironment, HEPATOCELLULAR carcinoma, TUMOR-infiltrating immune cells

Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study.

Authors: Zhao, Yongmei, Fang, Li Tai, Shen, Tsai-wei, Choudhari, Sulbha, Talsania, Keyur, Chen, Xiongfong, Shetty, Jyoti, Kriga, Yuliya, Tran, Bao, Zhu, Bin, Chen, Zhong, Chen, Wanqiu, Wang, Charles, Jaeger, Erich, Meerzaman, Daoud, Lu, Charles, Idler, Kenneth, Ren, Luyao, Zheng, Yuanting, Shi, Leming

Source: Scientific Data; 11/9/2021, Vol. 8 Issue 1, p1-14, 14p

Subject Terms: WHOLE genome sequencing, GENETIC mutation, SOMATIC mutation, EARLY detection of cancer, INDIVIDUALIZED medicine, GENOMES

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing.

Authors: Fang, Li Tai, Zhu, Bin, Zhao, Yongmei, Chen, Wanqiu, Yang, Zhaowei, Kerrigan, Liz, Langenbach, Kurt, de Mars, Maryellen, Lu, Charles, Idler, Kenneth, Jacob, Howard, Zheng, Yuanting, Ren, Luyao, Yu, Ying, Jaeger, Erich, Schroth, Gary P., Abaan, Ogan D., Talsania, Keyur, Lack, Justin, Shen, Tsai-Wei

Source: Nature Biotechnology; Sep2021, Vol. 39 Issue 9, p1151-1160, 10p

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Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy

Authors: Budhu, Anuradha, Pehrsson, Erica C., He, Aiwu, Goyal, Lipika, Kelley, Robin Kate, Dang, Hien, Xie, Changqing, Monge, Cecilia, Tandon, Mayank, Ma, Lichun, Revsine, Mahler, Kuhlman, Laura, Zhang, Karen, Baiev, Islam, Lamm, Ryan, Patel, Keyur, Kleiner, David E., Hewitt, Stephen M., Tran, Bao, Shetty, Jyoti, Wu, Xiaolin, Zhao, Yongmei, Shen, Tsai-Wei, Choudhari, Sulbha, Kriga, Yuliya, Ylaya, Kris, Warner, Andrew C., Edmondson, Elijah F., Forgues, Marshonna, Greten, Tim F., Wang, Xin Wei

Source: Cell Reports Medicine; June 2023, Vol. 4 Issue: 6

BiophysicalCharacteristics of Cholera Toxin and Escherichia coliHeat-Labile Enterotoxin Structure and Chemistry Lead to DifferentialToxicity.

Authors: Craft, John W.¹, Shen, Tsai-wei¹, Brier, Lindsey M.¹, Briggs, James M.¹

Source: Journal of Physical Chemistry B; Jan2015, Vol. 119 Issue 3, p1048-1061, 14p

A pharmacophore-based evolutionary approach for screening selective estrogen receptor modulators.

Authors: Yang, Jinn-Moon, Shen, Tsai-Wei

Source: Proteins; May2005, Vol. 59 Issue 2, p205-220, 16p

Consensus Scoring Criteria for Improving Enrichment in Virtual Screening

Authors: Yang, Jinn-Moon, Chen, Yen-Fu, Shen, Tsai-Wei, S. Kristal, Bruce, Frank Hsu, D.

Source: Journal of Chemical Information and Modeling; July 2005, Vol. 45 Issue: 4 p1134-1146, 13p

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Impact Of Swimming On Antioxidant Enzyme Status And Oxidative Markers In Old Rats.

Authors: Hsu, Ming-Fen¹, Shen, Tsai-Wei¹, Lu, Tsung-Hsien¹, Lin, Hsien-Tang¹, Yang, Chia-Chen¹, Lee, Jo-Ping¹, K, Mallikarjuna¹, Kuo, Chia-Hua¹

Source: Medicine & Science in Sports & Exercise; 2009 Supplement, Vol. 41, p502-502, 1p

Effect Of Acute Exercise On Lipid Peroxidation And Antioxidant Enzyme Status In Lean And Obese Zucker Rats.

Authors: Yang, Chia-Chen¹, Lin, Hsien-Tang¹, Shen, Tsai-Wei¹, Lu, Tsung-Hsien¹, Hsu, Ming-Fen¹, Hou, Chien-Wen¹, K, Mallikarjuna¹, Kuo, Chia-Hua¹

Source: Medicine & Science in Sports & Exercise; 2009 Supplement, Vol. 41, p3-3, 1p