ZK200775: A Phosphonate Quinoxalinedione AMPA Antagonist for Neuroprotection in Stroke and Trauma

Authors: Turski, Lechoslaw, Huth, Andreas, Sheardown, Malcolm, McDonald, Fiona, Neuhaus, Roland, Schneider, Herbert H., Dirnagl, Ulrich, Wiegand, Frank, Jacobsen, Poul, Ottow, Eckhard

Source: Proceedings of the National Academy of Sciences of the United States of America, 1998 Sep 01. 95(18), 10960-10965.

Access URL: https://www.jstor.org/stable/45999

Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice

Authors: Dadomo, Harold, Sanghez, Valentina, Di Cristo, Luisana, Lori, Andrea, Ceresini, Graziano, Malinge, Isabelle, Parmigiani, Stefano, Palanza, Paola, Sheardown, Malcolm, Bartolomucci, Alessandro

Source: In Progress in Neuropsychopharmacology & Biological Psychiatry 2011 35(6):1461-1471

The suitability of 129SvEv mice for studying depressive-like behaviour: Both males and females develop learned helplessness

Authors: Chourbaji, Sabine, Pfeiffer, Natascha, Dormann, Christof, Brandwein, Christiane, Fradley, Rosa, Sheardown, Malcolm, Gass, P.

Source: In Behavioural Brain Research 2010 211(1):105-110

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: A Neuroprotectant for Cerebral Ischemia

Authors: Sheardown, Malcolm J., Nielsen, Elsebet Ø., Hansen, Anker J., Jacobsen, Poul, Honoré, Tage

Source: Science, 1990 Feb 01. 247(4942), 571-574.

Access URL: https://www.jstor.org/stable/2873810

VDCC Gamma-8 Ion Channel

GPR 26 G-Protein Coupled Receptor

Treatment of ischemias by administration of 2,N.sup.6 -substituted adenosines

2, N.sup.6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias

The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

Authors: Rasmussen, Thøger, Fink-Jensen, Anders ^*, Sauerberg, Per, Swedberg, Michael D.B., Thomsen, Christian, Sheardown, Malcolm J., Jeppesen, Lone, Calligaro, David O., DeLapp, Neil W., Whitesitt, Celia, Ward, John S., Shannon, Harlan E., Bymaster, Frank P.

Source: In Schizophrenia Research 2001 49(1):193-201

Agonist-induced functional desensitization of recombinant human 5-HT2 receptors expressed in CHO-K1 cells

Authors: Porter, Richard H.P. ^*, Malcolm, Craig S., Allen, Nicola H., Lamb, Helen, Revell, Dean F., Sheardown, Malcolm J.

Source: In Biochemical Pharmacology 2001 62(4):431-438

Xanomeline, an M 1/M 4 preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice

Authors: Shannon, Harlan E. ^*, Rasmussen, Kurt, Bymaster, Frank P., Hart, John C., Peters, Steven C., Swedberg, Michael D.B., Jeppesen, Lone, Sheardown, Malcolm J., Sauerberg, Per, Fink-Jensen, Anders

Source: In Schizophrenia Research 2000 42(3):249-259

Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice

Authors: Rasmussen, Thøger, Sauerberg, Per, Nielsen, Erik B, Swedberg, Michael D.B, Thomsen, Christian, Sheardown, Malcolm J, Jeppesen, Lone, Calligaro, David O, DeLapp, Neil W, Whitesitt, Celia, Ward, John S, Shannon, Harlan E, Bymaster, Frank P, Fink-Jensen, Anders ^*

Source: In European Journal of Pharmacology 2000 402(3):241-246

Modulation of γ-aminobutyric acid responses in the rat optic nerve

Authors: Empson, Ruth M ^*, Sheardown, Malcolm J, Newberry, Nigel R

Source: In European Journal of Pharmacology 2000 401(3):339-342

Chlormethiazole inhibits epileptiform activity by potentiating GABA A receptor function

Authors: Empson, Ruth M., Gee, Veronica J., Sheardown, Malcolm J., Newberry, Nigel R. ^*

Source: In Brain Research 2000 884(1):31-34

Potential role of muscarinic receptors in schizophrenia

Authors: Bymaster, Frank P., Shannon, Harlan E., Rasmussen, Kurt, DeLapp, Neil W., Ward, John S., Calligaro, David O., Mitch, Charles H., Whitesitt, Celia, Ludvigsen, Thomas S., Sheardown, Malcolm, Swedberg, Michael, Rasmussen, Thøger, Olesen, Preben H., Jeppesen, Lone, Sauerberg, Per, Fink-Jensen, Anders

Source: In Life Sciences 1999 64(6):527-534

The effect of deficient muscarinic signaling on commonly reported biochemical effects in schizophrenia and convergence with genetic susceptibility loci in explaining symptom dimensions of psychosis.

Authors: Vakalopoulos, Costa, Tattersall, David, Sheardown, Malcolm James

Source: Frontiers in Pharmacology; Dec2014, Vol. 5, p1-15, 15p

Subject Terms: DIAGNOSIS of schizophrenia, PSYCHOSES, PATHOLOGICAL physiology, EXCITATORY amino acid agents, CYTOKINES

Phenylglycines can Evoke Quisqualate-primed Depolarizations in Rat Cingulate Cortex: An Effect Associated with [³H]DL-AP4 Uptake.

Authors: Sheardown, Malcolm J., Thomsen, Christian

Source: European Journal of Neuroscience; Dec1996, Vol. 8 Issue 12, p2599-2604, 6p

Cerebrovascular permeability and brain edema after cortical photochemical infarcts in the rat.

Authors: Laursen, Henning, Hansen, Anker, Sheardown, Malcolm

Source: Acta Neuropathologica; 1993, Vol. 86 Issue 4, p378-385, 8p

Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation.

Authors: Castillo, Gerardo M., Cummings, Joel A., Yang, Wenhua, Judge, Martin E., Sheardown, Malcolm J., Rimvall, Karin, Bondo Hansen, John, Snow, Alan D., Castillo, G M, Cummings, J A, Yang, W, Judge, M E, Sheardown, M J, Rimvall, K, Hansen, J B, Snow, A D

Source: Diabetes; Apr1998, Vol. 47 Issue 4, p612-620, 9p, 4 Color Photographs, 4 Black and White Photographs, 1 Chart, 6 Graphs

Subject Terms: AMYLOIDOSIS, PEPTIDES

Adenosine A1 and A3 selective N-alkoxypurines as novel cytokine modulators and neuroprotectants.

Authors: Knutsen, Lars J.S., Sheardown, Malcolm J., Roberts, Stanley M., Mogensen, John P., Olsen, Uffe Bang, Thomsen, Christian, Bowler, Andrew N.

Source: Drug Development Research; Nov1998, Vol. 45 Issue 3/4, p214-221, 8p