Neuropeptide Neuromedin B does not alter body weight and glucose homeostasis nor does it act as an insulin-releasing peptide

Authors: Domagoj Cikes, Patricio Atanes, Shane J. F. Cronin, Astrid Hagelkrüys, Guo-Cai Huang, Shanta J. Persaud, Josef M. Penninger

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/541c908da7104a1a89b1ad2a64fc0b28

Identification of Potential Plant-Derived Pancreatic Beta-Cell-Directed Agents Using New Custom-Designed Screening Method: Gymnema sylvestre as an Example

Authors: Altaf Al-Romaiyan, Shanta J. Persaud, Peter M. Jones

Source: Molecules, Vol 29, Iss 1, p 194 (2023)

Subject Terms: diabetes, screening, plant-derived therapies, beta-cell function, insulin, apoptosis, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/1/194; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/018778f4e32d426fa38b3b3641573b7a

SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells

Authors: Oladapo E. Olaniru, Jordan Cheng, Julia Ast, Anastasia Arvaniti, Patricio Atanes, Guo C. Huang, Aileen J.F. King, Peter M. Jones, Johannes Broichhagen, David J. Hodson, Shanta J. Persaud

Source: Molecular Metabolism, Vol 53, Iss , Pp 101285- (2021)

Subject Terms: GPR56, SNAP-tag, Trafficking, Islets, Apoptosis, CRISPR-Cas9, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877821001307; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/3df09aa019eb4776af546b1d54def1df

CXCL14 Inhibits Insulin Secretion Independently of CXCR4 or CXCR7 Receptor Activation or cAMP Inhibition

Authors: Patricio Atanes, Ross G. Hawkes, Oladapo E. Olaniru, Immaculada Ruz-Maldonado, Stefan Amisten, Shanta J. Persaud

Source: Cellular Physiology and Biochemistry, Vol 52, Iss 4, Pp 879-892 (2019)

Subject Terms: Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.cellphysiolbiochem.com/Articles/000061/; https://doaj.org/toc/1015-8987

Access URL: https://doaj.org/article/6240d29711184f5b87316cbd1614a673

The Placental Secretome: Identifying Potential Cross-Talk Between Placenta and Islet β-Cells

Authors: Robert Drynda, Shanta J. Persaud, James E. Bowe, Peter M Jones

Source: Cellular Physiology and Biochemistry, Vol 45, Iss 3, Pp 1165-1171 (2018)

Subject Terms: G protein-coupled receptor, β-cell, Pregnancy, Placental ligand, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/487357; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

Access URL: https://doaj.org/article/6b09bded5f3b484c8d30d449f878a24e

Identifying Signalling Pathways Regulated by GPRC5B in β-Cells by CRISPR-Cas9-Mediated Genome Editing

Authors: Patricio Atanes, Inmaculada Ruz-Maldonado, Ross Hawkes, Bo Liu, Shanta J. Persaud, Stefan Amisten

Source: Cellular Physiology and Biochemistry, Vol 45, Iss 2, Pp 656-666 (2018)

Subject Terms: β-cell, GPRC5B, CRISPR-Cas9, Apoptosis, Proliferation, Type 2 diabetes, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/487159; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

Access URL: https://doaj.org/article/28977d5856324210b0b082134d708d7e

Dynamic Profiling of Insulin Secretion and ATP Generation in Isolated Human and Mouse Islets Reveals Differential Glucose Sensitivity

Authors: Attilio Pingitore, Inmaculada Ruz-Maldonado, Bo Liu, Guo Cai Huang, Pratik Choudhary, Shanta J. Persaud

Source: Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1352-1359 (2017)

Subject Terms: Islets of Langerhans, Insulin secretion, ATP generation, Glucose transporters, Metabolic coupling, GLUT1, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/485532; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

Access URL: https://doaj.org/article/2560955b340a491bb1324654da86b8e8

The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice

Authors: Silvana Y. Romero-Zerbo, Inmaculada Ruz-Maldonado, Vanesa Espinosa-Jiménez, Alex Rafacho, Ana I. Gómez-Conde, Lourdes Sánchez-Salido, Nadia Cobo-Vuilleumier, Benoit R. Gauthier, Francisco J. Tinahones, Shanta J. Persaud, Francisco J. Bermúdez-Silva

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/37b7287839a5497faf990573a8d0dd27

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Stem cell therapy for diabetes: do we need to make beta cells?

Authors: Christopher J Burns, Shanta J Persaud, Peter M Jones

Source: Journal of Endocrinology; Dec2004, Vol. 183 Issue 3, p437-443, 7p

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Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

Authors: Lisa Sanderson, Marcelo da Silva, Gayathri N Sekhar, Rachel C Brown, Hollie Burrell-Saward, Mehmet Fidanboylu, Bo Liu, Lea Ann Dailey, Cécile A Dreiss, Chris Lorenz, Mark Christie, Shanta J Persaud, Vanessa Yardley, Simon L Croft, Margarita Valero, Sarah A Thomas

Source: PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009276 (2021)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/09b1e0c2a621449a9fa1562f25edd5f8

Direct Stimulatory Effects of the CB2 Ligand JTE 907 in Human and Mouse Islets

Authors: Inmaculada Ruz-Maldonado, Patricio Atanes, Guo Cai Huang, Bo Liu, Shanta J Persaud

Source: Cells, Vol 10, Iss 3, p 700 (2021)

Subject Terms: human islets, insulin secretion, apoptosis, proliferation, cannabinoid G protein-coupled receptors, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/3/700; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/7c975f5ac2ae4a11bed5f25c509f2fc4

The CaMK4/CREB/IRS-2 cascade stimulates proliferation and inhibits apoptosis of β-cells.

Authors: Bo Liu, Helena Barbosa-Sampaio, Peter M Jones, Shanta J Persaud, Dany S Muller

Source: PLoS ONE, Vol 7, Iss 9, p e45711 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23049845/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f3c3c4ba8adc426c98d895b3aef45dbf