Proteomic analysis of APOEε4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience

Authors: Keenan A. Walker, Yang An, Abhay Moghekar, Ruin Moaddel, Michael R. Duggan, Zhongsheng Peng, Qu Tian, Luke C. Pilling, Shannon M. Drouin, Mark A. Espeland, Stephen R Rapp, Kathleen M Hayden, Aladdin H. Shadyab, Ramon Casanova, Madhav Thambisetty, Peter R. Rapp, Dimitrios Kapogiannis, Luigi Ferrucci, Susan M. Resnick

Source: Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-18 (2024)

Subject Terms: Alzheimer’s disease, APOE, Resilience, Cognition, Proteomics, Immunity, Lipids, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1326

Access URL: https://doaj.org/article/ee7fd18cf0994326a5954b2b904a2e34

Machine learning analyses identify multi-modal frailty factors that selectively discriminate four cohorts in the Alzheimer’s disease spectrum: a COMPASS-ND study

Authors: Linzy Bohn, Shannon M. Drouin, G. Peggy McFall, Darryl B. Rolfson, Melissa K. Andrew, Roger A. Dixon

Source: BMC Geriatrics, Vol 23, Iss 1, Pp 1-18 (2023)

Subject Terms: Frailty, Deficit accumulation, Subjective cognitive impairment, Mild cognitive impairment, Alzheimer’s disease, Canadian Consortium on Neurodegeneration in Aging, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2318

Access URL: https://doaj.org/article/fe0d9a2ae7bf4d159f8911aff0474e3b

Gender specific factors contributing to cognitive resilience in APOE ɛ4 positive older adults in a population-based sample

Authors: Lidan Zheng, Ranmalee Eramudugolla, Nicolas Cherbuin, Shannon M. Drouin, Roger A. Dixon, Kaarin J. Anstey

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/26f3cd784f384dd2a96e54fe1a354ea6

Identifying key multi-modal predictors of incipient dementia in Parkinson’s disease: a machine learning analysis and Tree SHAP interpretation

Authors: G. Peggy McFall, Linzy Bohn, Myrlene Gee, Shannon M. Drouin, Harrison Fah, Wei Han, Liang Li, Richard Camicioli, Roger A. Dixon

Source: Frontiers in Aging Neuroscience, Vol 15 (2023)

Subject Terms: Parkinson’s disease, dementia, risk factors, biomarkers, random forest classifier, Tree SHapley Additive exPlanation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1124232/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/cb57e9deb24a42a8a198cfbbbdfcdd56

In multiple facets of subjective memory decline sex moderates memory predictions

Authors: Shannon M. Drouin, G. Peggy McFall, Roger A. Dixon

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)

Subject Terms: memory compensation, memory complaints, memory concerns, memory self‐efficacy, subjective memory decline, Victoria Longitudinal Study, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/3d2f02abe72d4ed897be2c160f2a7c47

Subjective memory concerns, poor vascular health, and male sex predict exacerbated memory decline trajectories: An integrative data-driven class and prediction analysis.

Authors: Drouin, Shannon M., ORCID 0000-0001-8767-5884. Department of Psychology, University of Alberta, Edmonton, AB, Canada, McFall, G. Peggy, ORCID 0000-0002-1284-7597. Department of Psychology, University of Alberta, Edmonton, AB, Canada, Dixon, Roger A.. Department of Psychology, University of Alberta, Edmonton, AB, Canada, rdixon@ualberta.ca

Source: Neuropsychology, Vol 36(2), Feb, 2022. pp. 128-139.

NLM Title Abbreviation: Neuropsychology

Publisher: US : American Psychological Association

Other Publishers: US : Educational Publishing Foundation
US : Philadelphia Clinical Neuropsychology Group
United Kingdom : Taylor & Francis

Supplemental Data: Experimental Materials Internet
Tables and Figures Internet

Publication Type: Journal; Peer Reviewed Journal

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