Clinical utility and predictive value of cerebrospinal fluid cell-free DNA profiling in non-small cell lung cancer patients with leptomeningeal metastasis

Authors: Sheng-Kai Liang, Wei-Yu Liao, Jin-Yuan Shih, Chia-Lin Hsu, Ching-Yao Yang, Shang-Gin Wu, Yen-Ting Lin, Yueh-Feng Wen, Lun-Che Chen, Yen-Fu Chen, Ya-Fang Chen, Yen-Heng Lin, Chong-Jen Yu

Source: Neoplasia: An International Journal for Oncology Research, Vol 60, Iss , Pp 101113- (2025)

Subject Terms: Non-small cell lung cancer (NSCLC), Leptomeningeal metastasis, Cell-free DNA (cfDNA), Cerebrospinal fluid (CSF), Intrathecal pemetrexed, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558624001544; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/b3d442c082314d269e570eaf7f0bd5b4

Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis

Authors: Shang‐Gin Wu, Chao‐Chi Ho, James Chih‐Hsin Yang, Shu‐Han Yu, Yen‐Feng Lin, Shu‐Chin Lin, Bin‐Chi Liao, Ching‐Yao Yang, Yen‐Ting Lin, Chong‐Jen Yu, Ya‐Ting Chuang, Wei‐Yu Liao, Kah Yi Yap, Weng Si Kou, Jin‐Yuan Shih

Source: Clinical and Translational Medicine, Vol 15, Iss 1, Pp n/a-n/a (2025)

Subject Terms: anti‐angiogenesis, atezolizumab, EGFR TKI resistance, immune cell, tumour microenvironment, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/6baafecd35de4b68b2b1383f366ecc9b

LncRNA SLCO4A1-AS1 suppresses lung cancer progression by sequestering the TOX4-NTSR1 signaling axis

Authors: Yi-Ling Chen, Yi-Nan Liu, Yen-Ting Lin, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hua Chang, Chia-Lang Hsu, Huey-Dong Wu, Jin-Yuan Shih

Source: Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-20 (2023)

Subject Terms: SLCO4A1-AS1, Long non-coding RNA, Cytoskeleton, Metastasis, Lung cancer, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/67e69c5d45e84907929dff4d4ef66aef

miR-204 suppresses cancer stemness and enhances osimertinib sensitivity in non-small cell lung cancer by targeting CD44

Authors: Shang-Gin Wu, Tzu-Hua Chang, Meng-Feng Tsai, Yi-Nan Liu, Yen-Lin Huang, Chia-Lang Hsu, Han-Nian Jheng, Jin-Yuan Shih

Source: Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102091- (2024)

Subject Terms: MT: Noncoding RNAs, miR-204, CD44, osimertinib resistance, epidermal growth factor receptor, EGFR, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253123003098; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/0fe9a2a3fca74c738931950645a3cfe1

MiR‐503 pleiotropically regulates epithelial‐mesenchymal transition and targets PTK7 to control lung cancer metastasis

Authors: Tzu‐Hsiu Tsai, Chien‐Hung Gow, Yi‐Nan Liu, Meng‐Feng Tsai, Tzu‐Hua Chang, Shang‐Gin Wu, Min‐Shu Hsieh, Kang‐Yi Su, Jin‐Yuan Shih

Source: Cancer Medicine, Vol 12, Iss 13, Pp 14511-14525 (2023)

Subject Terms: actin cytoskeleton, epithelial‐mesenchymal transition, focal adhesion kinase, miR‐503, protein tyrosine kinase 7, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/58e8d9efbdcb48779cafeca430fe60a8

Tissue or liquid rebiopsy? A prospective study for simultaneous tissue and liquid NGS after first‐line EGFR inhibitor resistance in lung cancer

Authors: Yen‐Ting Lin, Chao‐Chi Ho, Wei‐Hsun Hsu, Wei‐Yu Liao, Ching‐Yao Yang, Chong‐Jen Yu, Tzu‐Hsiu Tsai, James Chih‐Hsin Yang, Shang‐Gin Wu, Chia‐Lin Hsu, Min‐Shu Hsieh, Yen‐Lin Huang, Chia‐Ling Wu, Jin‐Yuan Shih

Source: Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)

Subject Terms: EGFR mutation, EGFR‐TKI resistance, next‐generation sequencing, NSCLC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/16337db479754d2fa1ffefc1d301d9fd

Survival outcomes and prognostic factors of lung cancer patients with the MET exon 14 skipping mutation: A single-center real-world study

Authors: Chien-Hung Gow, Min-Shu Hsieh, Yi-Lin Chen, Yi-Nan Liu, Shang-Gin Wu, Jin-Yuan Shih

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: adenocarcinoma, immunohistochemistry, MET exon 14 skipping, pulmonary sarcomatoid carcinoma, overall survival, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1113696/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/dda4673d0b774d658acbb8530f02b849

Multi‐kinase framework promotes proliferation and invasion of lung adenocarcinoma through activation of dynamin‐related protein 1

Authors: Kuei‐Pin Chung, Yen‐Lin Huang, Yi‐Jung Chen, Yi‐Hsiu Juan, Chia‐Lang Hsu, Kiichi Nakahira, Yen‐Tsung Huang, Mong‐Wei Lin, Shang‐Gin Wu, Jin‐Yuan Shih, Yih‐Leong Chang, Chong‐Jen Yu

Source: Molecular Oncology, Vol 15, Iss 2, Pp 560-578 (2021)

Subject Terms: cyclin‐dependent kinase 2, dynamin‐related protein 1, glycolytic serine synthesis, lung adenocarcinoma, mitochondria, prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/d8f61843129245abb046561cff9a0983

miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway

Authors: Yi-Nan Liu, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hua Chang, Tzu-Hsiu Tsai, Chien-Hung Gow, Hsin-Yi Wang, Jin-Yuan Shih

Source: Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 471-483 (2020)

Subject Terms: NSCLC, EGFR TKI, resistance, IRAK1, microRNA, NF-κB, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253120302869; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/ae291da348c047c08fdb18767d657f10

Prognostic Characteristics and Immunotherapy Response of Patients With Nonsquamous NSCLC With Kras Mutation in East Asian Populations: A Single-Center Cohort Study in Taiwan

Authors: Shang-Gin Wu, MD, PhD, Wei-Yu Liao, MD, PhD, Kang-Yi Su, PhD, Sung-Liang Yu, PhD, Yen-Lin Huang, MD, Chong-Jen Yu, MD, PhD, James Chih-Hsin Yang, MD, PhD, Jin-Yuan Shih, MD, PhD

Source: JTO Clinical and Research Reports, Vol 2, Iss 2, Pp 100140- (2021)

Subject Terms: Kras mutation, G12C, Lung cancer, Immunotherapy, PD-L1, Concomitant mutation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364320301910; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/e57e98f289ae455ba7fe9760df585bcb

An Observational Study of Acquired EGFR T790M-Dependent Resistance to EGFR-TKI Treatment in Lung Adenocarcinoma Patients in Taiwan

Authors: Shang-Gin Wu, Chi-Lu Chiang, Chien-Ying Liu, Chin-Chou Wang, Po-Lan Su, Te-Chun Hsia, Jin-Yuan Shih, Gee-Chen Chang

Source: Frontiers in Oncology, Vol 10 (2020)

Subject Terms: afatinib, epidermal growth factor receptor mutation, erlotinib, gefitinib, non-small cell lung cancer, tyrosine kinase inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2020.01481/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/d27779be756849c6b14ccc136e8fb9c0

The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation

Authors: Shang-Gin Wu, Chong-Jen Yu, James Chih-Hsin Yang, Jin-Yuan Shih

Source: Therapeutic Advances in Medical Oncology, Vol 12 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/07b7db0601e64926bfae9d5eb7556d69

High throughput sequencing of T-cell receptor repertoire using dry blood spots

Authors: Shang-Gin Wu, Wenjing Pan, Hongna Liu, Miranda L. Byrne-Steele, Brittany Brown, Mollye Depinet, Xiaohong Hou, Jian Han, Song Li

Source: Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)

Subject Terms: T cell receptor, TCR repertoire, CDR3, Dry blood spots, Next-generation sequence, Diversity, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12967-019-1796-4; https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/886eb718cb1c4dacab0d1663fd0e2f35

Management of acquired resistance to EGFR TKI–targeted therapy in advanced non-small cell lung cancer

Authors: Shang-Gin Wu, Jin-Yuan Shih

Source: Molecular Cancer, Vol 17, Iss 1, Pp 1-14 (2018)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12943-018-0777-1; https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/83528f6d0c654c93a54eed9a235f0375

Cone-Beam Computed Tomography-Derived Augmented Fluoroscopy Improves the Diagnostic Yield of Endobronchial Ultrasound-Guided Transbronchial Biopsy for Peripheral Pulmonary Lesions

Authors: Ching-Kai Lin, Hung-Jen Fan, Zong-Han Yao, Yen-Ting Lin, Yueh-Feng Wen, Shang-Gin Wu, Chao-Chi Ho

Source: Diagnostics, Vol 12, Iss 1, p 41 (2021)

Subject Terms: cone-beam computed tomography-derived augmented fluoroscopy, diagnostic yield, endobronchial ultrasound-guided transbronchial biopsy, navigation success rate, peripheral pulmonary lesion, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/12/1/41; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/a7a7bd5e431c431b983c53bb80a89c8a

Lung adenocarcinoma patients of young age have lower EGFR mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors

Authors: Shang-Gin Wu, Yih-Leong Chang, Chong-Jen Yu, Pan-Chyr Yang, Jin-Yuan Shih

Source: ERJ Open Research, Vol 3, Iss 3 (2017)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://openres.ersjournals.com/content/3/3/00092-2016.full; https://doaj.org/toc/2312-0541

Access URL: https://doaj.org/article/5268a066328f464abdd5f27603cf9c6d

Including total EGFR staining in scoring improves EGFR mutations detection by mutation-specific antibodies and EGFR TKIs response prediction.

Authors: Shang-Gin Wu, Yih-Leong Chang, Jou-Wei Lin, Chen-Tu Wu, Hsuan-Yu Chen, Meng-Feng Tsai, Yung-Chie Lee, Chong-Jen Yu, Jin-Yuan Shih

Source: PLoS ONE, Vol 6, Iss 8, p e23303 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21858063/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/38319c28a16449babc47690816ee48f6

Acute Cytomegalovirus Pneumonitis in Patient with Lymphomatoid Granulomatosis

Authors: Shang-Gin Wu, Tzu-Hsiu Tsai, Shang-Ju Wu

Source: Emerging Infectious Diseases, Vol 17, Iss 4, Pp 741-742 (2011)

Subject Terms: CMV pneumonitis, viruses, rituximab, lymphomatoid granulomatosis, cryptogenic organizing pneumonitis, letter, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/17/4/10-1035_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/856da67c0ddc4cc8b5aa87b741ba3b0e

Clinical outcomes of Atezolizumab Therapy for Previously-Treated Advanced-Stage Non-Small Cell Lung Cancer: A Real-World Study in Taiwan.

Authors: Shang-Gin Wu^1,2, Chi-Lu Chiang^3,4,5, Chin-Chou Wang⁶, Jen-Yu Hung^7,8,9, Te-Chun Hsia¹⁰, Chih-Hsi Kuo¹¹ chihhsikuo@gmail.com, Jin-Yuan Shih¹ jyshih@ntu.edu.tw

Source: Journal of Cancer. 2022, Vol. 13 Issue 9, p2922-2932. 11p.

Subject Terms: *LUNG cancer, *CANCER chemotherapy, *EPIDERMAL growth factor receptors, *ANAPLASTIC lymphoma kinase, *IMMUNOGLOBULINS

Discordant EGFR Mutations Between Primary and Metastatic Tumors of Non-Small Cell Lung Cancer: A Review of the Current Literature.

Authors: Shang-Gin Wu¹, Jin-Yuan Shih² jyshih@ntu.edu.tw

Source: Asia Pacific Journal of Oncology & Hematology. 2009, Vol. 1 Issue 3, p83-90. 8p. 1 Color Photograph, 1 Chart.

Subject Terms: *LUNG cancer, *CANCER patients, *CANCER treatment, *CANCER in women, *TUMORS, *GENETIC mutation, *PROTEIN-tyrosine kinases, *EPIDERMAL growth factor, *ONCOLOGY