Atlas of Metastatic Gastric Cancer Links Ferroptosis to Disease Progression and Immunotherapy Response

Authors: Cheng, Xiangdong, Dai, Enyu, Wu, Jibo, Flores, Natasha M., Chu, Yanshuo, Wang, Ruiping, Dang, Minghao, Xu, Zhiyuan, Han, Guangchun, Liu, Yunhe, Chatterjee, Deyali, Hu, Can, Ying, Jieer, Du, Yian, Yang, Litao, Guan, Xiaoqing, Mo, Shaowei, Cao, Xuanye, Pei, Guangsheng, Jiang, Jiahui, Lu, Xiaoyin, Benitez, Ana Morales, Waters, Rebecca E., Pizzi, Melissa Pool, Shanbhag, Namita, Fan, Yibo, Peng, Fuduan, Hanash, Samir M., Calin, George, Futreal, Andrew, Song, Shumei, Yee, Cassian, Mazur, Pawel K., Qin, Jiang-Jiang, Ajani, Jaffer A., Wang, Linghua

Source: In Gastroenterology December 2024 167(7):1345-1357

Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression

Authors: Wang, Ruiping, Song, Shumei, Qin, Jiangjiang, Yoshimura, Katsuhiro, Peng, Fuduan, Chu, Yanshuo, Li, Yuan, Fan, Yibo, Jin, Jiankang, Dang, Minghao, Dai, Enyu, Pei, Guangsheng, Han, Guangchun, Hao, Dapeng, Li, Yating, Chatterjee, Deyali, Harada, Kazuto, Pizzi, Melissa Pool, Scott, Ailing W., Tatlonghari, Ghia, Yan, Xinmiao, Xu, Zhiyuan, Hu, Can, Mo, Shaowei, Shanbhag, Namita, Lu, Yang, Sewastjanow-Silva, Matheus, Fouad Abdelhakeem, Ahmed Adel, Peng, Guang, Hanash, Samir M., Calin, George A., Yee, Cassian, Mazur, Pawel, Marsden, Autumn N., Futreal, Andrew, Wang, Zhenning, Cheng, Xiangdong, Ajani, Jaffer A., Wang, Linghua

Source: In Cancer Cell 14 August 2023 41(8):1407-1426

Proteogenomic landscape of gastric adenocarcinoma peritoneal metastases

Authors: Zhao, Shuangtao ^{1, 6}, Wang, Ruiping ¹, Song, Shumei ², Hao, Dapeng ¹, Han, Guangchun ¹, Song, Xingzhi ¹, Zhang, Jianhua ¹, Pizzi, Melissa Pool ², Shanbhag, Namita ², Futreal, Andrew ¹, Badgwell, Brian ³, Harada, Kazuto ², Calin, George ⁴, Vykoukal, Jody ⁵, Yu, Chuan-Yih ⁵, Katayama, Hiroyuki ⁵, Hanash, Samir M. ^{5, ∗}, Wang, Linghua ^{1, 7, ∗∗}, Ajani, Jaffer A. ^{2, ∗∗∗}

Source: In iScience 16 June 2023 26(6)

Retrospective Study of Claudin 18 Isoform 2 Prevalence and Prognostic Association in Gastric and Gastroesophageal Junction Adenocarcinoma.

Authors: Waters, Rebecca, Sewastjanow-Silva, Matheus, Yamashita, Kohei, Abdelhakeem, Ahmed, Iwata, Kenneth K., Moran, Diarmuid, Elsouda, Dina, Guerrero, Abraham, Pizzi, Melissa, Vicentini, Ernesto Rosa, Shanbhag, Namita, Ta, Anh, Chatterjee, Deyali, Ajani, Jaffer A.

Source: JCO Precision Oncology; 12/1/2024, Vol. 8, p1-15, 15p

Subject Terms: ESOPHAGOGASTRIC junction, PROGNOSIS, OVERALL survival, CLAUDINS, DEMOGRAPHIC characteristics

Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment.

Authors: Yibo Fan, Yuan Li, Xiaodan Yao, Jiangkang Jin, Scott, Ailing, Liu, Bovey, Shan Wang, Longfei Huo, Ying Wang, Ruiping Wang, Pizzi, Melissa Pool, Lang Ma, Shan Shao, Sewastjanow-Silva, Matheus, Waters, Rebecca, Chatterjee, Deyali, Liu, Bin, Shanbhag, Namita, Guang Peng, Calin, George Adrian

Source: Gut (0017-5749); Apr2023, Vol. 72 Issue 4, p624-637, 14p

Subject Terms: XENOGRAFTS, SOX transcription factors, TUMOR microenvironment, PERITONEAL cancer, MACROPHAGE colony-stimulating factor, MONONUCLEAR leukocytes, PROSTATE cancer

Localized Gastroesophageal Adenocarcinoma in the Elderly: Is Age a Factor Associated with Suboptimal Treatment?

Authors: Vassilakopoulou, Maria, Chen, Hsiang-Chun, Wang, Xuemei, Harada, Kazuto, Iwatsuki, Masaaki, Das, Prajnan, Blum Murphy, Mariela, Matamoros Jr., Aurelio, Sagebiel, Tara, Devine, Catherine, Thomas, Irene, Sanders, Elizabeth M., Shanbhag, Namita, Rogers, Jane E., Lee, Jeffrey H., Weston, Brian, Bhutani, Manoop S., Hofstetter, Wayne, Nguyen, Quynh-Nhu, Badgwell, Brian D.

Source: Oncology; 2023, Vol. 101 Issue 3, p153-158, 6p

Subject Terms: TUMOR surgery, STOMACH tumors, ADENOCARCINOMA, MEDICAL quality control, STATISTICS, CONFIDENCE intervals, MULTIVARIATE analysis, RETROSPECTIVE studies, REGRESSION analysis, TUMOR classification, KAPLAN-Meier estimator, TUMORS, ESOPHAGEAL tumors, PROPORTIONAL hazards models, OVERALL survival, TUMOR grading, SYMPTOMS, OLD age

Electronic Nicotine Delivery Systems and Oral Health: Emerging Risks and Concerns.

Authors: Ray, Priya, Shanbhag, Namita, Puranik, Manjunath P.

Source: Indian Journal of Dental Research; Oct-Dec2024, Vol. 35 Issue 4, p492-493, 2p

Subject Terms: ELECTRONIC cigarettes, SOCIAL media, MARKETING, INTERNET content, INTERNET sales

GRK3 is a poor prognosticator and serves as a therapeutic target in advanced gastric adenocarcinoma.

Authors: Li, Yuan, Fan, Yibo, Xu, Jinbang, Huo, Longfei, Scott, Ailing W., Jin, Jiankang, Yang, Boxuan, Shao, Shan, Ma, Lang, Wang, Ying, Yao, Xiaodan, Pool Pizzi, Melissa, Sewastjanow Da Silva, Matheus, Zhang, Guoliang, Zhuo, Lijuan, Cho, Eun Jeong, Dalby, Kevin N., Shanbhag, Namita D., Wang, Zhenning, Li, Wenliang

Source: Journal of Experimental & Clinical Cancer Research (17569966); 8/23/2022, Vol. 41 Issue 1, p1-19, 19p

Subject Terms: G protein coupled receptors, GENE silencing, YAP signaling proteins, GENOMICS, ADENOCARCINOMA

Company/Entity: UNITED States. Food & Drug Administration

Teledentistry and online referral system in Indonesian primary health care center during the COVID-19 pandemic: A narrative review.

Authors: Hariyani, Ninuk, Shanbhag, Namita, Wijayati, Ekawati, Prananta, Arie, Setyowati, Dini, Palupi, Retno

Source: Journal of International Society of Preventive & Community Dentistry; Jul/Aug2022, Vol. 12 Issue 4, p385-392, 8p

Subject Terms: PRIMARY health care, TELEDENTISTRY, COVID-19 pandemic, MEDICAL personnel, MEDICAL centers

Relationship between oral health status and oral health-related quality of life among patients with temporomandibular disorders in Bengaluru City: A cross-sectional comparative study.

Authors: Pawar, Pallavi, Puranik, Manjunath, Shanbhag, Namita

Source: Journal of Indian Association of Public Health Dentistry; Jul-Sep2022, Vol. 20 Issue 3, p287-292, 6p

Cross-Cultural Adaptation of Kannada Version of Modified Dental Anxiety Scale Among an Adult Indian Population.

Authors: GUPTA, GAURAV¹ gauravbenu@gmail.com, SHANBHAG, NAMITA², PURANIK, MANJUNATH P.³

Source: Journal of Clinical & Diagnostic Research. Sep2015, Vol. 9 Issue 9, p34-38. 5p.

Subject Terms: *FEAR of dentists, *PSYCHOMETRICS, *TEST validity

Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma.

Authors: Shumei Song, Qiongrong Chen, Yuan Li, Guang Lei, Scott, Ailing, Longfei Huo, Li, Cordelia Y., Estrella, Jeannelyn Santiano, Correa, Arlene, Pizzi, Melissa Pool, Lang Ma, Jiankang Jin, Bin Liu, Ying Wang, Lianchun Xiao, Hofstetter, Wayne L., Lee, Jeffrey H., Weston, Brian, Bhutani, Manoop, Shanbhag, Namita

Source: Gut (0017-5749); Dec2021, Vol. 70 Issue 12, p2238-2248, 11p

Subject Terms: ESOPHAGEAL cancer, CANCER stem cells, CASTRATION-resistant prostate cancer, PROGNOSIS, HEAD & neck cancer, ESOPHAGOGASTRIC junction cancer

Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma.

Authors: Dapeng Hao, Siyuan He, Kazuto Harada, Pizzi, Melissa Pool, Yang Lu, Pujun Guan, Lu Chen, Ruiping Wang, Shaojun Zhang, Sewastjanow-Silva, Matheus, Abdelhakeem, Ahmed, Shanbhag, Namita, Bhutani, Manoop, Guangchun Han, Lee, Jeffrey H., Shuangtao Zhao, Weston, Brian, Murphy, Mariela Blum, Waters, Rebecca, Estrella, Jeannelyn Santiano

Source: Gut (0017-5749); Nov2021, Vol. 70 Issue 11, p2055-2065, 11p

Subject Terms: BLADDER cancer, CHRONIC pancreatitis, GENE expression, CIRCULATING tumor DNA, PROGNOSIS

National sample surveys show poor households face catastrophic expenditure for oral healthcare services in India.

Authors: Prasad, Banuru, Tripathy, Jaya, Bera, Om, Shanbhag, Namita

Source: Journal of Family Medicine & Primary Care; Aug2021, Vol. 10 Issue 8, p2853-2858, 6p

Subject Terms: CONSUMPTION (Economics), HOUSEHOLDS, MEDICAL care costs, PUBLIC spending, PUBLIC sector, PUBLIC investments

Geographic Terms: INDIA

Association between oral health status and family quality of life among schoolchildren -- A cross-sectional study.

Authors: Farooq, Mohammed Umar, Puranik, Manjunath P., Shanbhag, Namita

Source: Journal of Global Oral Health; Jul-Dec2021, Vol. 4 Issue 2, p94-101, 8p

Patient-derived cell lines and orthotopic mouse model of peritoneal carcinomatosis recapitulate molecular and phenotypic features of human gastric adenocarcinoma.

Authors: Song, Shumei, Xu, Yan, Huo, Longfei, Zhao, Shuangtao, Wang, Ruiping, Li, Yuan, Scott, Ailing W., Pizzi, Melissa Pool, Wang, Ying, Fan, Yibo, Harada, Kazuto, Jin, Jiankang, Ma, Lang, Yao, Xiaodan, Shanbhag, Namita D., Gan, Qiong, Roy-Chowdhuri, Sinchita, Badgwell, Brian D., Wang, Zhenning, Wang, Linghua

Source: Journal of Experimental & Clinical Cancer Research (17569966); 6/23/2021, Vol. 40 Issue 1, p1-15, 15p

Subject Terms: LABORATORY mice, CELL lines, PHENOTYPES, CANCER stem cells, ANIMAL disease models, PERITONEAL cancer

Frequency and Implications of Paratracheal Lymph Node Metastases in Resectable Esophageal or Gastroesophageal Junction Adenocarcinoma.

Authors: Kazuto Harada^1,2, Hyunsoo Hwang³, Xuemei Wang³, Abdelhakeem, Ahmed¹, Masaaki Iwatsuki^1,2, Murphy, Mariela A. Blum¹, Maru, Dipen M.⁴, Weston, Brian⁵, Lee, Jeffrey H.⁵, Rogers, Jane E.⁶, Thomas, Irene¹, Shanbhag, Namita¹, MeinaMeina Zhao¹, Bhutani, Manoop S.⁵, Quynh-Nhu Nguyen⁷, Swisher, Stephen G.⁸, Naruhiko Ikoma⁹, Badgwell, Brian D.⁹, Hofstetter, Wayne L.⁸, Ajani, Jaffer A.¹ jajani@mdanderson.org

Source: Annals of Surgery. Apr2021, Vol. 273 Issue 4, p751-757. 7p.

Low metabolic activity in primary gastric adenocarcinoma is associated with resistance to chemoradiation and the presence of signet ring cells.

Authors: Harada, Kazuto, Patnana, Madhavi, Wang, Xuemei, Iwatsuki, Masaaki, Murphy, Mariela A. Blum, Zhao, Meina, Das, Prajnan, Minsky, Bruce D., Weston, Brian, Lee, Jeffrey H., Bhutani, Manoop S., Estrella, Jeannelyn S., Shanbhag, Namita, Ikoma, Naruhiko, Badgwell, Brian D., Ajani, Jaffer A.

Source: Surgery Today; Oct2020, Vol. 50 Issue 10, p1223-1231, 9p

Subject Terms: CHEMORADIOTHERAPY, POSITRON emission tomography, ADENOCARCINOMA, LOGISTIC regression analysis, COMPUTED tomography

Brain metastases in patients with upper gastrointestinal cancer is associated with proximally located adenocarcinoma and lymph node metastases.

Authors: Harada, Kazuto, Hwang, Hyunsoo, Wang, Xuemei, Abdelhakeem, Ahmed, Iwatsuki, Masaaki, Murphy, Mariela A. Blum, Maru, Dipen M., Weston, Brian, Lee, Jeffrey H., Rogers, Jane E., Trail, Allison, Shanbhag, Namita, Zhao, Meina, Bhutani, Manoop S., Nguyen, Quynh-Nhu, Swisher, Stephen G., Ikoma, Naruhiko, Das, Prajnan, Hofstetter, Wayne L., Badgwell, Brian D.

Source: Gastric Cancer; Sep2020, Vol. 23 Issue 5, p904-912, 9p

Subject Terms: GASTROINTESTINAL cancer, STEREOTACTIC radiosurgery, BRAIN metastasis, LYMPH nodes, ESOPHAGOGASTRIC junction, STOMACH cancer

Identification of circulating tumor cells using 4‐color fluorescence in situ hybridization: Validation of a noninvasive aid for ruling out lung cancer in patients with low‐dose computed tomography–detected lung nodules.

Authors: Katz, Ruth L., Zaidi, Tanweer M., Pujara, Deep, Shanbhag, Namita D., Truong, Duy, Patil, Shekhar, Mehran, Reza J., El‐Zein, Randa A., Shete, Sanjay S., Kuban, Joshua D.

Source: Cancer Cytopathology; Aug2020, Vol. 128 Issue 8, p553-562, 10p