The eEF1A protein in cancer: Clinical significance, oncogenic mechanisms, and targeted therapeutic strategies

Authors: Zhang, Weicheng, Wang, Jiyan, Shan, Changliang

Source: In Pharmacological Research June 2024 204

Malate, a natural inhibitor of 6PGD, improves the efficacy of chemotherapy in lung cancer

Authors: Sun, Mingming, Feng, Qi, Yan, Qi, Zhao, Huifang, Wang, Haiyan, Zhang, Shuai, Shan, Changliang, Liu, Shuangping, Wang, Jiyan, Zhai, Hongyan

Source: In Lung Cancer April 2024 190

Transcriptome analysis identifies genetic risk markers and explores the pathogenesis for inflammatory bowel disease

Authors: Wang, Jiyan ^{a, 1}, Sun, Mingming ^{a, 1}, Liu, Xu ^b, Yan, Qi ^a, Gao, Qingle ^a, Ni, Kemin ^c, Yang, Juze ^d, Zhang, Shuai ^e, Zhang, Chunze ^{c, f, ⁎}, Shan, Changliang ^{a, ⁎}

Source: In BBA - Molecular Basis of Disease March 2024 1870(3)

Interruption of bile acid enterohepatic circulation inhibits glycogen synthesis and promotes hepatocellular carcinoma progression

Authors: Wang, Jiyan, Dai, Xintong, Chang, Hongkai, Gao, Qingle, Guo, Jianshuang, Yang, Juze, Zhang, Shuai, Shan, Changliang

Source: Genes & diseases. 10(6):2218-2221

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194881819.0x000001&indx=1&recIds=ETOCvdc_100194881819.0x000001

Glucose-6-phosphate dehydrogenase: a therapeutic target for ovarian cancer

Authors: Wang, Chenxi, Yu, Chenxi, Chang, Hongkai, Song, Jiaqi, Zhang, Shuai, Zhao, Jianguo, Wang, Jiyan, Wang, Tao, Qi, Qi, Shan, Changliang

Source: Expert opinion on therapeutic targets. 27(8):733-743

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193502385.0x000001&indx=1&recIds=ETOCvdc_100193502385.0x000001

PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism

Authors: Sun, Mingming, Li, Leilei, Niu, Yujia, Wang, Yingzhi, Yan, Qi, Xie, Fei, Qiao, Yaya, Song, Jiaqi, Sun, Huanran, Li, Zhen, Lai, Sizhen, Chang, Hongkai, Zhang, Han, Wang, Jiyan, Yang, Chenxin, Zhao, Huifang, Tan, Junzhen, Li, Yanping, Liu, Shuangping, Lu, Bin, Liu, Min, Kong, Guangyao, Zhao, Yujun, Zhang, Chunze, Lin, Shu-Hai, Luo, Cheng, Zhang, Shuai, Shan, Changliang

Source: Acta pharmaceutica sinica B. 13(1):157-173

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186197001.0x000001&indx=1&recIds=ETOCvdc_100186197001.0x000001

Site-directed late-stage diversification of macrocyclic nannocystins facilitating anticancer SAR and mode of action studiesElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2md00393g

Authors: Zhang, Han, Tian, Yunfeng, Yuan, Xiaoya, Xie, Fei, Yu, Siqi, Cai, Jiayou, Sun, Bin, Shan, Changliang, Zhang, Weicheng

Source: RSC medicinal chemistry. 14(2):299-312

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178404782.0x000001&indx=1&recIds=ETOCvdc_100178404782.0x000001

A model for identification of potential phase-separated proteins based on protein sequence, structure and cellular distribution

Authors: Wang, Jiyan, Chang, Hongkai, Quan, Xiaojing, Dai, Xintong, Wang, Yan, Wang, Chenxi, Zhang, Shuai, Shan, Changliang

Source: In International Journal of Biological Macromolecules 15 July 2023 243

Correction: 4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis.

Authors: Shan, Changliang, Lu, Zhaoliang, Li, Zhen, Sheng, Hao, Fan, Jun, Qi, Qi, Liu, Shuangping, Zhang, Shuai

Source: Cell Death & Disease; 2/26/2025, Vol. 16 Issue 1, p1-4, 4p

A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells

Authors: Guo, Jianshuang, Liu, Kaihui, Wang, Jiyan, Jiang, Hao, Zhang, Mengyi, Liu, Yang, Shan, Changliang, Hu, Fangzhong, Fu, Wenzheng, Zhang, Chunze, Li, Jing, Chen, Yue

Source: In Biochemical Pharmacology June 2022 200

PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3

Authors: Sun, Mingming, Sheng, Hao, Wu, Tingfeng, Song, Jiaqi, Sun, Huanran, Wang, Yingzhi, Wang, Jiyan, Li, Zhen, Zhao, Huifang, Tan, Junzhen, Li, Yanping, Chen, Guo, Huang, Qingrong, Zhang, Yuan, Lan, Bei, Liu, Shuangping, Shan, Changliang, Zhang, Shuai

Source: In Biochemical Pharmacology October 2021 192

APEX2‐based Proximity Labeling of Atox1 Identifies CRIP2 as a Nuclear Copper‐binding Protein that Regulates Autophagy Activation

Authors: Chen, Lin, Li, Na, Zhang, Meiqi, Sun, Mingming, Bian, Jiaxuan, Yang, Bo, Li, Zhengcunxiao, Wang, Jiayu, Li, Fei, Shi, Xiaomeng, Wang, Yuan, Yuan, Feng, Zou, Peng, Shan, Changliang, Wang, Jing

Source: Angewandte Chemie. 133(48):25550-25559

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141565832.0x000001&indx=1&recIds=ETOCvdc_100141565832.0x000001

Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1

Authors: Feng, Qi, Li, Xiuru, Sun, Wenjing, Sun, Mingming, Li, Zhen, Sheng, Hao, Xie, Fei, Zhang, Shuai, Shan, Changliang

Source: In Biochemical Pharmacology August 2020 178

AMPK-dependent phosphorylation of HDAC8 triggers PGM1 expression to promote lung cancer cell survival under glucose starvation

Authors: Li, Yanping, Liang, Ronghui, Sun, Mingming, Li, Zhen, Sheng, Hao, Wang, Jiyan, Xu, Pengjuan, Liu, Shuangping, Yang, Wancai, Lu, Bin, Zhang, Shuai, Shan, Changliang

Source: In Cancer Letters 28 May 2020 478:82-92

PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1

Authors: Xie, Fei, Zhang, Han, Zhu, Kongkai, Jiang, Cheng‐Shi, Zhang, Xiaoya, Chang, Hongkai, Qiao, Yaya, Sun, Mingming, Wang, Jiyan, Wang, Mukuo, Tan, Junzhen, Wang, Tao, Zhao, Lianmei, Zhang, Yuan, Lin, Jianping, Zhang, Chunze, Liu, Shuangping, Zhao, Jianguo, Luo, Cheng, Zhang, Shuai, Shan, Changliang

Source: MedComm. 4(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182055198.0x000001&indx=1&recIds=ETOCvdc_100182055198.0x000001

HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition

Authors: Wang, Xuanyu, Feng, Qi, Yu, Hongnv, Zhou, Xingzhi, Shan, Changliang, Zhang, Qinggao, Liu, Shuangping

Source: In Life Sciences 15 March 2020 245

γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A

Authors: Gao, Xue, Zhao, Liang, Liu, Shuangping, Li, Yuancheng, Xia, Siyuan, Chen, Dong, Wang, Mei, Wu, Shaoxiong, Dai, Qing, Vu, Hieu, Zacharias, Lauren, DeBerardinis, Ralph, Lim, Esther, Metallo, Christian, Boggon, Titus J., Lonial, Sagar, Lin, Ruiting, Mao, Hui, Pan, Yaozhu, Shan, Changliang, Chen, Jing

Source: In Molecular Cell 19 December 2019 76(6):857-871

Selenium nanoparticles as new strategy to potentiate γδ T cell anti-tumor cytotoxicity through upregulation of tubulin-α acetylation

Authors: Hu, Yi, Liu, Ting, Li, Jingxia, Mai, Fengyi, Li, Jiawei, Chen, Yan, Jing, Yanyun, Dong, Xin, Lin, Li, He, Junyi, Xu, Yan, Shan, Changliang, Hao, Jianlei, Yin, Zhinan, Chen, Tianfeng, Wu, Yangzhe

Source: In Biomaterials November 2019 222

Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment

Authors: Huang, Ke, Jiang, Lulu, Liang, Ronghui, Li, Huiti, Ruan, Xiaoxue, Shan, Changliang, Ye, Deyong, Zhou, Lu

Source: In European Journal of Medicinal Chemistry 15 April 2019 168:45-57

Metabolomics reveals the effect of valproic acid on MCF-7 and MDA-MB-231 cells

Authors: Zhou, Xingzhi, Li, Zhen, Wang, Xuanyu, Jiang, Ge, Shan, Changliang, Liu, Shuangping

Source: Xenobiotica. 50(3):252-260

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097162560.0x000001&indx=1&recIds=ETOCvdc_100097162560.0x000001