Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension

Authors: Sarasa Isobe, Ramesh V. Nair, Helen Y. Kang, Lingli Wang, Jan-Renier Moonen, Tsutomu Shinohara, Aiqin Cao, Shalina Taylor, Shoichiro Otsuki, David P. Marciano, Rebecca L. Harper, Mir S. Adil, Chongyang Zhang, Mauro Lago-Docampo, Jakob Körbelin, Jesse M. Engreitz, Michael P. Snyder, Marlene Rabinovitch

Source: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/77e16fe3567e4a3f89266732e6c31cf1

KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress

Authors: Jan-Renier Moonen, James Chappell, Minyi Shi, Tsutomu Shinohara, Dan Li, Maxwell R. Mumbach, Fan Zhang, Ramesh V. Nair, Joseph Nasser, Daniel H. Mai, Shalina Taylor, Lingli Wang, Ross J. Metzger, Howard Y. Chang, Jesse M. Engreitz, Michael P. Snyder, Marlene Rabinovitch

Source: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/dd0de669b721470b8265ca8d188386af

Monocyte-released HERV-K dUTPase engages TLR4 and MCAM causing endothelial mesenchymal transition

Authors: Shoichiro Otsuki, Toshie Saito, Shalina Taylor, Dan Li, Jan-Renier Moonen, David P. Marciano, Rebecca L. Harper, Aiqin Cao, Lingli Wang, Maria E. Ariza, Marlene Rabinovitch

Source: JCI Insight, Vol 6, Iss 15 (2021)

Subject Terms: Inflammation, Vascular biology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/cef82f1c90464af295d891c0012529c9

The Role of Neutrophils and Neutrophil Elastase in Pulmonary Arterial Hypertension

Authors: Shalina Taylor, Omar Dirir, Roham T. Zamanian, Marlene Rabinovitch, A. A. Roger Thompson

Source: Frontiers in Medicine, Vol 5 (2018)

Subject Terms: neutrophils, neutrophil elastase, pulmonary hypertension, pulmonary arterial hypertension, vascular remodeling, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmed.2018.00217/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/e8f7b2c39c284c54ae03411251b7e7b6