Post‐diagnostic metformin and statin use and risk of biochemical recurrence in Veterans diagnosed with prostate cancer

Authors: Khan, Saira, Chang, Su‐Hsin, Seyerle, Amanda A., Wang, Mei, Hicks, Veronica, Drake, Bettina F.

Source: Prostate. 83(12):1150-1157

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187897044.0x000001&indx=1&recIds=ETOCvdc_100187897044.0x000001

BinomiRare: A robust test for association of a rare genetic variant with a binary outcome for mixed models and any case-control proportion

Authors: Sofer, Tamar, Lee, Jiwon, Kurniansyah, Nuzulul, Jain, Deepti, Laurie, Cecelia A., Gogarten, Stephanie M., Conomos, Matthew P., Heavner, Ben, Hu, Yao, Kooperberg, Charles, Haessler, Jeffrey, Vasan, Ramachandran S., Cupples, L. Adrienne, Coombes, Brandon J., Seyerle, Amanda, Gharib, Sina A., Chen, Han, O’Connell, Jeffrey R., Zhang, Man, Gottlieb, Daniel J., Psaty, Bruce M., Longstreth, W.T., Jr., Rotter, Jerome I., Taylor, Kent D., Rich, Stephen S., Guo, Xiuqing, Boerwinkle, Eric, Morrison, Alanna C., Pankow, James S., Johnson, Andrew D., Pankratz, Nathan, Reiner, Alex P., Redline, Susan, Smith, Nicholas L., Rice, Kenneth M., Schifano, Elizabeth D.

Source: In Human Genetics and Genomics Advances 8 July 2021 2(3)

Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations

Authors: Avery, Christy L., Wassel, Christina L., Richard, Melissa A., Highland, Heather M., Bien, Stephanie, Zubair, Niha, Soliman, Elsayed Z., Fornage, Myriam, Bielinski, Suzette J., Tao, Ran, Seyerle, Amanda A., Shah, Sanjiv J., Lloyd-Jones, Donald M., Buyske, Steven, Rotter, Jerome I., Post, Wendy S., Rich, Stephen S., Hindorff, Lucia A., Jeff, Janina M., Shohet, Ralph V., Sotoodehnia, Nona, Lin, Dan Yu, Whitsel, Eric A., Peters, Ulrike, Haiman, Christopher A., Crawford, Dana C., Kooperberg, Charles, North, Kari E.

Source: In Heart Rhythm April 2017 14(4):572-580

Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy

Authors: Napier, Melanie, Franceschini, Nora, Gondalia, Rahul, Stewart, James, Méndez-Giráldez, Raúl, Sitlani, Colleen, Seyerle, Amanda, Highland, Heather, Li, Yun, Wilhelmsen, Kirk, Yan, Song, Duan, Qing, Roach, Jeffrey, Yao, Jie, Guo, Xiuqing, Taylor, Kent, Heckbert, Susan, Rotter, Jerome, North, Kari, Reiner, Alexander, Zhang, Zhu-Ming, Tinker, Lesley, Liao, Duanping, Laurie, Cathy, Gogarten, Stephanie, Lin, Henry, Brody, Jennifer, Bartz, Traci, Psaty, Bruce, Sotoodehnia, Nona, Soliman, Elsayed, Avery, Christy, Whitsel, Eric

Source: Scientific reports. 8(1):1-8

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129221529.0x000001&indx=1&recIds=ETOCvdc_100129221529.0x000001

Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos

Authors: Conomos, Matthew P., Laurie, Cecelia A., Stilp, Adrienne M., Gogarten, Stephanie M., McHugh, Caitlin P., Nelson, Sarah C., Sofer, Tamar, Fernández-Rhodes, Lindsay, Justice, Anne E., Graff, Mariaelisa, Young, Kristin L., Seyerle, Amanda A., Avery, Christy L., Taylor, Kent D., Rotter, Jerome I., Talavera, Gregory A., Daviglus, Martha L., Wassertheil-Smoller, Sylvia, Schneiderman, Neil, Heiss, Gerardo, Kaplan, Robert C., Franceschini, Nora, Reiner, Alex P., Shaffer, John R., Barr, R. Graham, Kerr, Kathleen F., Browning, Sharon R., Browning, Brian L., Weir, Bruce S., Avilés-Santa, M. Larissa, Papanicolaou, George J., Lumley, Thomas, Szpiro, Adam A., North, Kari E., Rice, Ken, Thornton, Timothy A., Laurie, Cathy C.

Source: In The American Journal of Human Genetics 7 January 2016 98(1):165-184

Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program

Authors: Seyerle, Amanda A., Laurie, Cecelia A., Coombes, Brandon J., Jain, Deepti, Conomos, Matthew P., Brody, Jennifer, Chen, Ming-Huei, Gogarten, Stephanie M., Beutel, Kathleen M., Gupta, Namrata, Heckbert, Susan R., Jackson, Rebecca D., Johnson, Andrew D., Ko, Darae, Manson, JoAnn E., McKnight, Barbara, Metcalf, Ginger A., Morrison, Alanna C., Reiner, Alexander P., Sofer, Tamar, Tang, Weihong, Wiggins, Kerri L., Boerwinkle, Eric, de Andrade, Mariza, Gabriel, Stacey B., Gibbs, Richard A., Laurie, Cathy C., Psaty, Bruce M., Vasan, Ramachandran S., Rice, Ken, Kooperberg, Charles, Pankow, James S., Smith, Nicholas L., Pankratz, Nathan

Source: Circulation.Genomic and precision medicine. 16(2):e003532-e003532

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189375800.0x000001&indx=1&recIds=ETOCvdc_100189375800.0x000001

Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval

Authors: Seyerle, Amanda A., Young, Alicia M., Jeff, Janina M., Melton, Phillip E., Jorgensen, Neal W., Lin, Yi, Carty, Cara L., Deelman, Ewa, Heckbert, Susan R., Hindorff, Lucia A., Jackson, Rebecca D., Martin, Lisa W., Okin, Peter M., Perez, Marco V., Psaty, Bruce M., Soliman, Elsayed Z., Whitsel, Eric A., North, Kari E., Laston, Sandra, Kooperberg, Charles, Avery, Christy L.

Source: Epidemiology, 2014 Nov 01. 25(6), 790-798.

Access URL: http://www.jstor.org/stable/24759403

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

Authors: Ntalla, Ioanna, Weng, Lu-Chen, Cartwright, James H., Hall, Amelia Weber, Sveinbjornsson, Gardar, Tucker, Nathan R., Choi, Seung Hoan, Chaffin, Mark D., Roselli, Carolina, Barnes, Michael R., Mifsud, Borbala, Warren, Helen R., Hayward, Caroline, Marten, Jonathan, Cranley, James J., Concas, Maria Pina, Gasparini, Paolo, Boutin, Thibaud, Kolcic, Ivana, Polasek, Ozren, Rudan, Igor, Araujo, Nathalia M., Lima-Costa, Maria Fernanda, Ribeiro, Antonio Luiz P., Souza, Renan P., Tarazona-Santos, Eduardo, Giedraitis, Vilmantas, Ingelsson, Erik, Mahajan, Anubha, Morris, Andrew P., Del Greco M, Fabiola, Foco, Luisa, Gögele, Martin, Hicks, Andrew A., Cook, James P., Lind, Lars, Lindgren, Cecilia M., Sundström, Johan, Nelson, Christopher P., Riaz, Muhammad B., Samani, Nilesh J., Sinagra, Gianfranco, Ulivi, Sheila, Kähönen, Mika, Mishra, Pashupati P., Mononen, Nina, Nikus, Kjell, Caulfield, Mark J., Dominiczak, Anna, Padmanabhan, Sandosh, Montasser, May E., O'Connell, Jeff R., Ryan, Kathleen, Shuldiner, Alan R., Aeschbacher, Stefanie, Conen, David, Risch, Lorenz, Thériault, Sébastien, Hutri-Kähönen, Nina, Lehtimäki, Terho, Lyytikäinen, Leo-Pekka, Raitakari, Olli T., Barnes, Catriona L. K., Campbell, Harry, Joshi, Peter K., Wilson, James F., Isaacs, Aaron, Kors, Jan A., van Duijn, Cornelia M., Huang, Paul L., Gudnason, Vilmundur, Harris, Tamara B., Launer, Lenore J., Smith, Albert V., Bottinger, Erwin P., Loos, Ruth J. F., Nadkarni, Girish N., Preuss, Michael H., Correa, Adolfo, Mei, Hao, Wilson, James, Meitinger, Thomas, Müller-Nurasyid, Martina, Peters, Annette, Waldenberger, Melanie, Mangino, Massimo, Spector, Timothy D., Rienstra, Michiel, van de Vegte, Yordi J., van der Harst, Pim, Verweij, Niek, Kääb, Stefan, Schramm, Katharina, Sinner, Moritz F., Strauch, Konstantin, Cutler, Michael J., Fatkin, Diane, London, Barry, Olesen, Morten, Roden, Dan M., Benjamin Shoemaker, M., Gustav Smith, J., Biggs, Mary L., Bis, Joshua C., Brody, Jennifer A., Psaty, Bruce M., Rice, Kenneth, Sotoodehnia, Nona, De Grandi, Alessandro, Fuchsberger, Christian, Pattaro, Cristian, Pramstaller, Peter P., Ford, Ian, Wouter Jukema, J., Macfarlane, Peter W., Trompet, Stella, Dörr, Marcus, Felix, Stephan B., Völker, Uwe, Weiss, Stefan, Havulinna, Aki S., Jula, Antti, Sääksjärvi, Katri, Salomaa, Veikko, Guo, Xiuqing, Heckbert, Susan R., Lin, Henry J., Rotter, Jerome I., Taylor, Kent D., Yao, Jie, de Mutsert, Renée, Maan, Arie C., Mook-Kanamori, Dennis O., Noordam, Raymond, Cucca, Francesco, Ding, Jun, Lakatta, Edward G., Qian, Yong, Tarasov, Kirill V., Levy, Daniel, Lin, Honghuang, Newton-Cheh, Christopher H., Lunetta, Kathryn L., Murray, Alison D., Porteous, David J., Smith, Blair H., Stricker, Bruno H., Uitterlinden, André, van den Berg, Marten E., Haessler, Jeffrey, Jackson, Rebecca D., Kooperberg, Charles, Peters, Ulrike, Reiner, Alexander P., Whitsel, Eric A., Alonso, Alvaro, Arking, Dan E., Boerwinkle, Eric, Ehret, Georg B., Soliman, Elsayed Z., Avery, Christy L., Gogarten, Stephanie M., Kerr, Kathleen F., Laurie, Cathy C., Seyerle, Amanda A., Stilp, Adrienne, Assa, Solmaz, Abdullah Said, M., Yldau van der Ende, M., Lambiase, Pier D., Orini, Michele, Ramirez, Julia, Van Duijvenboden, Stefan, Arnar, David O., Gudbjartsson, Daniel F., Holm, Hilma, Sulem, Patrick, Thorleifsson, Gudmar, Thorolfsdottir, Rosa B., Thorsteinsdottir, Unnur, Benjamin, Emelia J., Tinker, Andrew, Stefansson, Kari, Ellinor, Patrick T., Jamshidi, Yalda, Lubitz, Steven A., Munroe, Patricia B.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174617786.0x000001&indx=1&recIds=ETOCvdc_100174617786.0x000001

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GWAS of QRS duration identifies new loci specific to Hispanic/Latino populations.

Authors: Swenson, Brenton R., Louie, Tin, Lin, Henry J., Méndez-Giráldez, Raúl, Below, Jennifer E., Laurie, Cathy C., Kerr, Kathleen F., Highland, Heather, Thornton, Timothy A., Ryckman, Kelli K., Kooperberg, Charles, Soliman, Elsayed Z., Seyerle, Amanda A., Guo, Xiuqing, Taylor, Kent D., Yao, Jie, Heckbert, Susan R., Darbar, Dawood, Petty, Lauren E., McKnight, Barbara

Source: PLoS ONE; 6/28/2019, Vol. 14 Issue 6, p1-15, 15p

Subject Terms: HISPANIC Americans, NUCLEAR proteins, COMPUTATIONAL biology, SUDDEN death, MEMBRANE proteins

Geographic Terms: EUROPE

Association of Antidepressant Medication Type With the Incidence of Cardiovascular Disease in the ARIC Study.

Authors: Almuwaqqat, Zakaria, Jokhadar, Maan, Norby, Faye L., Lutsey, Pamela L., O'Neal, Wesley T., Seyerle, Amanda, Soliman, Elsayed Z., Chen, Lin Y., Bremner, J. Douglas, Vaccarino, Viola, Shah, Amit J., Alonso, Alvaro

Source: Journal of the American Heart Association; 6/4/2019, Vol. 8 Issue 11, p1-9, 9p

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Pharmacogenomics Study of Thiazide Diuretics and QT Interval in Multi-Ethnic Populations: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE)

Authors: Seyerle, Amanda A, Sitlani, Colleen M, Noordam, Raymond, Gogarten, Stephanie M, Li, Jin, Li, Xiaohui, Evans, Daniel S, Sun, Fangui, Laaksonen, Maarit A, Isaacs, Aaron, Kristiansson, Kati, Highland, Heather M, Stewart, James D, Harris, Tamara B, Trompet, Stella, Bis, Joshua C, Peloso, Gina M, Brody, Jennifer A, Broer, Linda, Duan, Qing, Stilp, Adrienne M, O’Donnell, Christopher J, Macfarlane, Peter W, Floyd, James S, Kors, Jan A, Lin, Henry J, Li-Gao, Ruifang, Sofer, Tamar, Méndez-Giráldez, Raúl, Cummings, Steven R, Heckbert, Susan R, Hofman, Albert, Ford, Ian, Li, Yun, Launer, Lenore J, Porthan, Kimmo, Napier, Melanie D, Kerr, Kathleen F, Reiner, Alexander P, Rice, Kenneth M, Roach, Jeffrey, Buckley, Brendan M, Soliman, Elsayed Z, de Mutsert, Renée, Sotoodehnia, Nona, Uitterlinden, André G, North, Kari E, Lee, Craig R, Gudnason, Vilmundur, Stürmer, Til, Rosendaal, Frits R, Taylor, Kent D, Wiggins, Kerri L, Wilson, James G, Chen, Yii-Der I, Kaplan, Robert C, Wilhelmsen, Kirk, Cupples, L Adrienne, Salomaa, Veikko, van Duijn, Cornelia, Jukema, J Wouter, Liu, Yongmei, Mook-Kanamori, Dennis O, Lange, Leslie A, Vasan, Ramachandran S, Smith, Albert V, Stricker, Bruno H, Laurie, Cathy C, Rotter, Jerome I, Whitsel, Eric A, Psaty, Bruce M, Avery, Christy L, Busch, Evan, Newton-Cheh, Christopher

Source: Seyerle, A. A., C. M. Sitlani, R. Noordam, S. M. Gogarten, J. Li, X. Li, D. S. Evans, et al. 2017. “Pharmacogenomics Study of Thiazide Diuretics and QT Interval in Multi-Ethnic Populations: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE).” The pharmacogenomics journal :10.1038/tpj.2017.10. doi:10.1038/tpj.2017.10. http://dx.doi.org/10.1038/tpj.2017.10.

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Relation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773415/pdf/; The pharmacogenomics journal

Access URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:34868972

Genetic Epidemiology: The Potential Benefits and Challenges of Using Genetic Information to Improve Human Health.

Authors: Seyerle, Amanda A., Avery, Christy L.

Source: North Carolina Medical Journal; Nov/Dec2013, Vol. 74 Issue 6, p505-508, 4p

Large-scale pharmacogenomic study of sulfonylureas and the QT, JT, and QRS intervals: CHARGE Pharmacogenomics Working Group

Authors: Floyd, James S, Sitlani, Colleen M, Avery, Christy L, Noordam, Raymond, Li, Xiaohui, Smith, Albert V, Gogarten, Stephanie M, Li, Jin, Broer, Linda, Evans, Daniel S, Trompet, Stella, Brody, Jennifer A, Stewart, James D, Eicher, John D, Seyerle, Amanda A, Roach, Jeffrey, Lange, Leslie A, Lin, Henry J, Kors, Jan A, Harris, Tamara B, Li-Gao, Ruifang, Sattar, Naveed, Cummings, Steven R, Wiggins, Kerri L, Napier, Melanie D, Stürmer, Til, Bis, Joshua C, Kerr, Kathleen F, Uitterlinden, André G, Taylor, Kent D, Stott, David J, de Mutsert, Renée, Launer, Lenore J, Méndez-Giráldez, Raúl, Sotoodehnia, Nona, Soliman, Elsayed Z, Li, Yun, Duan, Qing, Rosendaal, Frits R, Slagboom, P Eline, Wilhelmsen, Kirk C, Reiner, Alexander P, Chen, Yii-Der I, Heckbert, Susan R, Kaplan, Robert C, Rice, Kenneth M, Jukema, J Wouter, Johnson, Andrew D, Liu, Yongmei, Mook-Kanamori, Dennis O, Gudnason, Vilmundur, Wilson, James G, Rotter, Jerome I, Laurie, Cathy C, Psaty, Bruce M, Whitsel, Eric A, Cupples, L Adrienne, Stricker, Bruno H, Busch, Evan

Source: Floyd, J. S., C. M. Sitlani, C. L. Avery, R. Noordam, X. Li, A. V. Smith, S. M. Gogarten, et al. 2016. “Large-scale pharmacogenomic study of sulfonylureas and the QT, JT, and QRS intervals: CHARGE Pharmacogenomics Working Group.” The pharmacogenomics journal :10.1038/tpj.2016.90. doi:10.1038/tpj.2016.90. http://dx.doi.org/10.1038/tpj.2016.90.

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Relation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468495/pdf/; The pharmacogenomics journal

Access URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:33490964

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