Design of Crotoxin-Based Peptides with Potentiator Activity Targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator

Authors: Ravatin, Marc, Odolczyk, Norbert, Servel, Nathalie, Guijarro, J. Iñaki, Tagat, Eric, Chevalier, Benoit, Baatallah, Nesrine, Corringer, Pierre-Jean, Lukács, Gergely L., Edelman, Aleksander, Zielenkiewicz, Piotr, Chambard, Jean-Marie, Hinzpeter, Alexandre, Faure, Grazyna

Source: In Journal of Molecular Biology 1 February 2023 435(3)

Correlating genotype with phenotype using CFTR‐mediated whole‐cell Cl− currents in human nasal epithelial cells

Authors: Noel, Sabrina, Servel, Nathalie, Hatton, Aurélie, Golec, Anita, Rodrat, Mayuree, Ng, Demi R. S., Li, Hongyu, Pranke, Iwona, Hinzpeter, Alexandre, Edelman, Aleksander, Sheppard, David N., Sermet‐Gaudelus, Isabelle

Source: Journal of physiology. 600(6):1515-1531

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154952383.0x000001&indx=1&recIds=ETOCvdc_100154952383.0x000001

Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆ F508CFTR Dysfunction: Impact in Cystic Fibrosis

Authors: Faure, Grazyna, Bakouh, Naziha, Lourdel, Stéphane, Odolczyk, Norbert, Premchandar, Aiswarya, Servel, Nathalie, Hatton, Aurélie, Ostrowski, Maciej K., Xu, Haijin, Saul, Frederick A., Moquereau, Christelle, Bitam, Sara, Pranke, Iwona, Planelles, Gabrielle, Teulon, Jacques, Herrmann, Harald, Roldan, Ariel, Zielenkiewicz, Piotr, Dadlez, Michal, Lukacs, Gergely L., Sermet-Gaudelus, Isabelle, Ollero, Mario, Corringer, Pierre-Jean, Edelman, Aleksander

Source: In Journal of Molecular Biology 17 July 2016 428(14):2898-2915

Prolactin independent rescue of mouse corpus luteum life span: identification of prolactin and luteinizing hormone target genes.

Authors: Bachelot, Anne, Beaufaron, Julie, Servel, Nathalie

Source: American Journal of Physiology; September 2009 pt1, Vol. 297 Issue 3, pE676-E684, 9p

Correlating genotype with phenotype using CFTR‐mediated whole‐cell Cl⁻ currents in human nasal epithelial cells.

Authors: Noel, Sabrina^1,2 (AUTHOR), Servel, Nathalie^1,2 (AUTHOR), Hatton, Aurélie^1,2 (AUTHOR), Golec, Anita^1,2 (AUTHOR), Rodrat, Mayuree^3,4 (AUTHOR), Ng, Demi R. S.³ (AUTHOR), Li, Hongyu³ (AUTHOR), Pranke, Iwona^1,2 (AUTHOR), Hinzpeter, Alexandre^1,2 (AUTHOR), Edelman, Aleksander^1,2 (AUTHOR), Sheppard, David N.³ (AUTHOR) d.n.sheppard@bristol.ac.uk, Sermet‐Gaudelus, Isabelle^1,2,5,6 (AUTHOR) isabelle.sermet@aphp.fr

Source: Journal of Physiology. Mar2022, Vol. 600 Issue 6, p1515-1531. 17p.

Subject Terms: *CYSTIC fibrosis transmembrane conductance regulator, *EPITHELIAL cells, *ION channels, *VOLTAGE-gated ion channels, *NASAL mucosa

Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR.

Authors: Baatallah, Nesrine, Elbahnsi, Ahmad, Mornon, Jean-Paul, Chevalier, Benoit, Pranke, Iwona, Servel, Nathalie, Zelli, Renaud, Décout, Jean-Luc, Edelman, Aleksander, Sermet-Gaudelus, Isabelle, Callebaut, Isabelle, Hinzpeter, Alexandre

Source: Cellular & Molecular Life Sciences; Dec2021, Vol. 78 Issue 23, p7813-7829, 17p

Subject Terms: BINDING sites, CYSTIC fibrosis transmembrane conductance regulator, MOLECULAR dynamics, MUTANT proteins, SMALL molecules

New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation.

Authors: Bitam, Sara, Elbahnsi, Ahmad, Creste, Geordie, Pranke, Iwona, Chevalier, Benoit, Berhal, Farouk, Hoffmann, Brice, Servel, Nathalie, Tondelier, Danielle, Hatton, Aurelie, Moquereau, Christelle, Faria Da Cunha, Mélanie, Pastor, Alexandra, Lepissier, Agathe, Hinzpeter, Alexandre, Mornon, Jean-Paul, Prestat, Guillaume, Edelman, Aleksander, Callebaut, Isabelle, Gravier-Pelletier, Christine

Source: Scientific Reports; 3/25/2021, Vol. 11 Issue 1, p1-12, 12p

Subject Terms: PHOSPHINIC acid, CHEMICAL derivatives, CYSTIC fibrosis transmembrane conductance regulator, GENETIC mutation, MOLECULAR docking

Prolactin Receptor Signaling Is Essential for Perinatal Brown Adipocyte Function: A Role for Insulin-like Growth Factor-2.

Authors: Viengchareun, Say^1,2, Servel, Nathalie^3,4, Fève, Bruno^1,2, Freemark, Michael^3,4,5, Lombès, Marc^1,2, Binart, Nadine^3,4 binart@necker.fr

Source: PLoS ONE. 2008, Vol. 3 Issue 2, p1-13. 13p. 1 Diagram, 1 Chart, 5 Graphs.

Subject Terms: *MAMMAL physiology, *PROLACTIN, *PLACENTAL hormones, *BROWN adipose tissue, *FAT cells, *MICE physiology, *PHENOTYPES, *BODY temperature regulation, *ADRENERGIC receptors

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Cis variants identified in F508del complex alleles modulate CFTR channel rescue by small molecules.

Authors: Baatallah, Nesrine, Bitam, Sara, Martin, Natacha, Servel, Nathalie, Costes, Bruno, Mekki, Chadia, Chevalier, Benoit, Pranke, Iwona, Simonin, Juliette, Girodon, Emmanuelle, Hoffmann, Brice, Mornon, Jean‐Paul, Callebaut, Isabelle, Sermet‐Gaudelus, Isabelle, Fanen, Pascale, Edelman, Aleksander, Hinzpeter, Alexandre

Source: Human Mutation; Apr2018, Vol. 39 Issue 4, p506-514, 9p

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Author Correction: New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation.

Authors: Bitam, Sara, Elbahnsi, Ahmad, Creste, Geordie, Pranke, Iwona, Chevalier, Benoit, Berhal, Farouk, Hoffmann, Brice, Servel, Nathalie, Baatalah, Nesrine, Tondelier, Danielle, Hatton, Aurelie, Moquereau, Christelle, Faria Da Cunha, Mélanie, Pastor, Alexandra, Lepissier, Agathe, Hinzpeter, Alexandre, Mornon, Jean‑Paul, Prestat, Guillaume, Edelman, Aleksander, Callebaut, Isabelle

Source: Scientific Reports; 9/15/2021, Vol. 11 Issue 1, p1-2, 2p

Subject Terms: PHOSPHINIC acid, CYSTIC fibrosis transmembrane conductance regulator

Discovery of novel potent ΔF508- CFTR correctors that target the nucleotide binding domain.

Authors: Odolczyk, Norbert, Fritsch, Janine, Norez, Caroline, Servel, Nathalie, da Cunha, Melanie Faria, Bitam, Sara, Kupniewska, Anna, Wiszniewski, Ludovic, Colas, Julien, Tarnowski, Krzysztof, Tondelier, Danielle, Roldan, Ariel, Saussereau, Emilie L., Melin‐Heschel, Patricia, Wieczorek, Grzegorz, Lukacs, Gergely L., Dadlez, Michal, Faure, Grazyna, Herrmann, Harald, Ollero, Mario

Source: EMBO Molecular Medicine; Oct2013, Vol. 5 Issue 10, p1484-1501, 18p

Ontogenesis of female-to-male sex-reversal in XX polled goats.

Authors: Pailhoux, Eric, Vigier, Bernard, Vaiman, Daniel, Servel, Nathalie, Chaffaux, Stéphane, Cribiu, Edmond P., Cotinot, Corinne

Source: Developmental Dynamics; May2002, Vol. 224 Issue 1, p39-50, 12p

A 11.7-kb deletion triggers intersexuality and polledness in goats.

Authors: Pailhoux, Eric, Vigier, Bernard, Chaffaux, Stéphane, Servel, Nathalie, Taourit, Sead, Furet, Jean-Pierre, Fellous, Marc, Grosclaude, François, Cribiu, Edmond P., Cotinot, Corinne, Vaiman, Daniel

Source: Nature Genetics; Dec2001, Vol. 29 Issue 4, p453, 6p

Subject Terms: GENETIC sex determination, INTERSEXUALITY

Time course of female-to-male sex reversal in 38,XX fetal and postnatal pigs.

Authors: Pailhoux, Eric, Parma, Pietro, Sundström, Jari, Vigier, Bernard, Servel, Nathalie, Kuopio, Teijo, Locatelli, Alain, Pelliniemi, Lauri J., Cotinot, Corinne

Source: Developmental Dynamics; Nov2001, Vol. 222 Issue 3, p328-340, 13p

Cloning and characterization of a full-length cDNA coding for ovine aldolase B from fetal mesonephros

Authors: Gianquinto, Laurence, Pailhoux, Eric A., Bezard, Jacqueline, Servel, Nathalie, Kirszenbaum, Marek, Cotinot, Corinne

Source: In BBA - Gene Structure and Expression 1994 1219(1):223-227