Precision psychiatry

Authors: Serretti, Alessandro

Source: Brazilian Journal of Psychiatry. April 2022 44(2)

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Specific symptomatology profile associated with treatment resistant depression: A multicentric study from the Group for the Study of Resistant Depression with a focus on sex

Authors: Luca, Maria ^a, Luca, Antonina ^b, Messina, Antonino ^c, Bartova, Lucie ^d, Kasper, Siegfried ^{d, e}, Zohar, Joseph ^f, Souery, Daniel ^g, Montgomery, Stuart ^h, Ferentinos, Panagiotis ⁱ, Rujescu, Dan ^d, Mendlewicz, Julien ^j, Zanardi, Raffaella ^{k, l}, Ferri, Raffaele ^m, Lanuzza, Bartolo ^m, Benedetti, Francesco ^{k, l}, Pecorino, Basilio ^b, Baune, Bernhard T. ^{n, o, p}, Fanelli, Giuseppe ^{q, r}, Fabbri, Chiara ^q, Serretti, Alessandro ^{b, m, ⁎}

Source: In Journal of Affective Disorders 15 April 2025 375:249-255

Oropharyngeal microbiota in patients with psychotic disorders: A scoping review on compositional and functional alterations

Authors: Scala, Mauro ^{a, b, c, d, ⁎}, del Rocío González Soltero, María ^{c, e, ⁎⁎}, Bellido Esteban, Alberto ^c, Biscaia Fernández, José Miguel ^c, Romero-Ferreiro, Verónica ^{b, c, f}, Serretti, Alessandro ^{g, h}, Fanelli, Giuseppe ^{a, i, 1}, Rodriguez-Jimenez, Roberto ^{b, d, f, 1}

Source: In Progress in Neuropsychopharmacology & Biological Psychiatry 20 March 2025 137

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Authors: Adams, Mark J., Streit, Fabian, Meng, Xiangrui, Awasthi, Swapnil, Adey, Brett N., Choi, Karmel W., Chundru, V. Kartik, Coleman, Jonathan R.I., Ferwerda, Bart, Foo, Jerome C., Gerring, Zachary F., Giannakopoulou, Olga, Gupta, Priya, Hall, Alisha S.M., Harder, Arvid, Howard, David M., Hübel, Christopher, Kwong, Alex S.F., Levey, Daniel F., Mitchell, Brittany L., Ni, Guiyan, Ota, Vanessa K., Pain, Oliver, Pathak, Gita A., Schulte, Eva C., Shen, Xueyi, Thorp, Jackson G., Walker, Alicia, Yao, Shuyang, Zeng, Jian, Zvrskovec, Johan, Aarsland, Dag, Actkins, Ky'Era V., Adli, Mazda, Agerbo, Esben, Aichholzer, Mareike, Aiello, Allison, Air, Tracy M., Als, Thomas D., Andersson, Evelyn, Andlauer, Till F.M., Arolt, Volker, Ask, Helga, Bäckman, Julia, Badola, Sunita, Ballard, Clive, Banasik, Karina, Bass, Nicholas J., Beekman, Aartjan T.F., Belangero, Sintia, Bigdeli, Tim B., Binder, Elisabeth B., Bjerkeset, Ottar, Bjornsdottir, Gyda, Børte, Sigrid, Bränn, Emma, Braun, Alice, Brodersen, Thorsten, Brückl, Tanja M., Brunak, Søren, Bruun, Mie T., Burmeister, Margit, Buspavanich, Pichit, Bybjerg-Grauholm, Jonas, Byrne, Enda M., Cai, Jianwen, Campbell, Archie, Campbell, Megan L., Campos, Adrian I., Castelao, Enrique, Cervilla, Jorge, Chaumette, Boris, Chen, Chia-Yen, Chen, Hsi-Chung, Chen, Zhengming, Cichon, Sven, Colodro-Conde, Lucía, Corbett, Anne, Corfield, Elizabeth C., Couvy-Duchesne, Baptiste, Craddock, Nick, Dannlowski, Udo, Davies, Gail, de Geus, E.J.C., Deary, Ian J., Degenhardt, Franziska, Dehghan, Abbas, DePaulo, J. Raymond, Deuschle, Michael, Didriksen, Maria, Dinh, Khoa Manh, Direk, Nese, Djurovic, Srdjan, Docherty, Anna R., Domschke, Katharina, Dowsett, Joseph, Drange, Ole Kristian, Dunn, Erin C., Eaton, William, Einarsson, Gudmundur, Eley, Thalia C., Elsheikh, Samar S.M., Engelmann, Jan, Benros, Michael E., Erikstrup, Christian, Escott-Price, Valentina, Fabbri, Chiara, Fang, Yu, Finer, Sarah, Frank, Josef, Free, Robert C., Gallo, Linda, Gao, He, Gill, Michael, Gilles, Maria, Goes, Fernando S., Gordon, Scott Douglas, Grove, Jakob, Gudbjartsson, Daniel F., Gutierrez, Blanca, Hahn, Tim, Hall, Lynsey S., Hansen, Thomas F., Haraldsson, Magnus, Hartman, Catharina A., Havdahl, Alexandra, Hayward, Caroline, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hickie, Ian B., Hjalgrim, Henrik, Hjerling-Leffler, Jens, Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M., Hovatta, Iiris, Huang, Qin Qin, Hucks, Donald, Huider, Floris, Hunt, Karen A., Ialongo, Nicholas S., Ising, Marcus, Isometsä, Erkki, Jansen, Rick, Jiang, Yunxuan, Jones, Ian, Jones, Lisa A., Jonsson, Lina, Kanai, Masahiro, Karlsson, Robert, Kasper, Siegfried, Kendler, Kenneth S., Kessler, Ronald C., Kloiber, Stefan, Knowles, James A., Koen, Nastassja, Kraft, Julia, Kranzler, Henry R., Krebs, Kristi, Kallak, Theodora Kunovac, Kutalik, Zoltán, Lahtela, Elisa, Lake, Marilyn, Larsen, Margit Hørup, Lenze, Eric J., Lewins, Melissa, Lewis, Glyn, Li, Liming, Lin, Bochao Danae, Lin, Kuang, Lind, Penelope A., Liu, Yu-Li, MacIntyre, Donald J., MacKinnon, Dean F., Maher, Brion S., Maier, Wolfgang, Marshe, Victoria S., Martinez-Levy, Gabriela A., Matsuda, Koichi, Mbarek, Hamdi, McGuffin, Peter, Medland, Sarah E., Meinert, Susanne, Mikkelsen, Christina, Mikkelsen, Susan, Milaneschi, Yuri, Millwood, Iona Y., Molina, Esther, Mondimore, Francis M., Mortensen, Preben Bo, Mulsant, Benoit H., Naamanka, Joonas, Najman, Jake M., Nauck, Matthias, Nenadić, Igor, Nielsen, Kasper R., Nolt, Ilja M., Nordentoft, Merete, Nöthen, Markus M., Nyegaard, Mette, O'Donovan, Michael C., Oddsson, Asmundur, Oliveira, Adrielle M., Olsen, Catherine M., Oskarsson, Hogni, Ostrowski, Sisse Rye, Owen, Michael J., Packer, Richard, Palviainen, Teemu, Pan, Pedro M., Pato, Carlos N., Pato, Michele T., Pedersen, Nancy L., Pedersen, Ole Birger, Peyrot, Wouter J., Potash, James B., Preisig, Martin, Preuss, Michael H., Quiroz, Jorge A., Renteria, Miguel E., Reynolds III, Charles F., Rice, John P., Sakaue, Saori, Santoro, Marcos L., Schoevers, Robert A., Schork, Andrew, Schulze, Thomas G., Send, Tabea S., Shi, Jianxin, Sigurdsson, Engilbert, Singh, Kritika, Sinnamon, Grant C.B., Sirignano, Lea, Smeland, Olav B., Smith, Daniel J., Sofer, Tamar, Sørensen, Erik, Srinivasan, Sundararajan, Stefansson, Hreinn, Stefansson, Kari, Straub, Peter, Su, Mei-Hsin, Tadic, André, Teismann, Henning, Teumer, Alexander, Thapar, Anita, Thomson, Pippa A., Thørner, Lise Wegner, Topaloudi, Apostolia, Tsai, Shih-Jen, Tzoulaki, Ioanna, Uhl, George, Uitterlinden, André G., Ullum, Henrik, Umbricht, Daniel, Ursano, Robert J., Van der Auwera, Sandra, van Hemert, Albert M., Veluchamy, Abirami, Viktorin, Alexander, Völzke, Henry, Walters, G. Bragi, Wang, Xiaotong, Wani, Agaz, Weissman, Myrna M., Wellmann, Jürgen, Whiteman, David C., Wildman, Derek, Willemsen, Gonneke, Williams, Alexander T., Winsvold, Bendik S., Witt, Stephanie H., Xiong, Ying, Zillich, Lea, Zwart, John-Anker, Twenty-Three and Me Research Team, China Kadoorie Biobank Collaborative Group, Estonian Biobank Research Team, Genes & Health Research Team, HUNT All-In Psychiatry, The BioBank Japan Project, VA Million Veteran Program, Andreassen, Ole A., Baune, Bernhard T., Berger, Klaus, Boomsma, Dorret I., Børglum, Anders D., Breen, Gerome, Cai, Na, Coon, Hilary, Copeland, William E., Creese, Byron, Cruz-Fuentes, Carlos S., Czamara, Darina, Davis, Lea K., Derks, Eske M., Domenici, Enrico, Elliott, Paul, Forstner, Andreas J., Gawlik, Micha, Gelernter, Joel, Grabe, Hans J., Hamilton, Steven P., Hveem, Kristian, John, Catherine, Kaprio, Jaakko, Kircher, Tilo, Krebs, Marie-Odile, Kuo, Po-Hsiu, Landén, Mikael, Lehto, Kelli, Levinson, Douglas F., Li, Qingqin S., Lieb, Klaus, Loos, Ruth J.F., Lu, Yi, Lucae, Susanne, Luykx, Jurjen J., Maes, Hermine H.M., Magnusson, Patrik K., Martin, Hilary C., Martin, Nicholas G., McQuillin, Andrew, Middeldorp, Christel M., Milani, Lili, Mors, Ole, Müller, Daniel J., Müller-Myhsok, Bertram, Okada, Yukinori, Oldehinkel, Albertine J., Paciga, Sara A., Palmer, Colin N.A., Paschou, Peristera, Penninx, Brenda W.J.H., Perlis, Roy H., Peterson, Roseann E., Pistis, Giorgio, Polimanti, Renato, Porteous, David J., Posthuma, Danielle, Rabinowitz, Jill A., Reichborn-Kjennerud, Ted, Reif, Andreas, Rice, Frances, Ricken, Roland, Rietschel, Marcella, Rivera, Margarita, Rück, Christian, Salum, Giovanni A., Schaefer, Catherine, Sen, Srijan, Serretti, Alessandro, Skalkidou, Alkistis, Smoller, Jordan W., Stein, Dan J., Stein, Frederike, Stein, Murray B., Sullivan, Patrick F., Tesli, Martin, Thorgeirsson, Thorgeir E., Tiemeier, Henning, Timpson, Nicholas J., Uddin, Monica, Uher, Rudolf, van Heel, David A., Verweij, Karin J.H., Walters, Robin G., Wassertheil-Smoller, Sylvia, Wendland, Jens R., Werge, Thomas, Zwinderman, Aeilko H., Kuchenbaecker, Karoline, Wray, Naomi R., Ripke, Stephan, Lewis, Cathryn M., McIntosh, Andrew M.

Source: In Cell 6 February 2025 188(3):640-652

Hypomanic symptoms in major depressive disorder: Prognostic impact and treatment issues

Authors: Olgiati, Paolo, Kasper, Siegfried, Zohar, Joseph, Souery, Daniel, Montgomery, Stuart, Ferentinos, Panagiotis, Rujescu, Dan, Zanardi, Raffaella, Fugger, Gernot, Ferri, Raffaele, Tripodi, Mariangela, Baune, Bernhard T., Fabbri, Chiara, Mendlewicz, Julien, Serretti, Alessandro

Source: In Journal of Affective Disorders 15 January 2025 369:1021-1030

Exploring the use of immunomethylomics in the characterization of depressed patients: A proof-of-concept study

Authors: Van Assche, Evelien ^a, Hohoff, Christa ^a, Su Atil, Ecem ^a, Wissing, Sophia M. ^a, Serretti, Alessandro ^d, Fabbri, Chiara ^e, Pisanu, Claudia ^f, Squassina, Alessio ^f, Minelli, Alessandra ^{g, h}, Baune, Bernhard T. ^{a, b, c, ⁎}

Source: In Brain Behavior and Immunity January 2025 123:597-605

Psychological impact of neovagina creation and uterus transplantation in the patients affected from Mayer–Rokitanski–Kuster–Hauser syndrome: A narrative review

Authors: Pecorino, Basilio ^{a, ⁎}, Scibilia, Giuseppe ^b, Ferrara, Martina ^c, Veroux, Pierfrancesco ^d, Mereu, Liliana ^e, Serretti, Alessandro ^f, Scollo, Paolo ^g

Source: In European Journal of Obstetrics & Gynecology and Reproductive Biology November 2024 302:356-361

Multimodal brain-derived subtypes of Major depressive disorder differentiate patients for anergic symptoms, immune-inflammatory markers, history of childhood trauma and treatment-resistance

Authors: Colombo, Federica, Calesella, Federico, Bravi, Beatrice, Fortaner-Uyà, Lidia, Monopoli, Camilla, Tassi, Emma, Carminati, Matteo, Zanardi, Raffaella, Bollettini, Irene, Poletti, Sara, Lorenzi, Cristina, Spadini, Sara, Brambilla, Paolo, Serretti, Alessandro, Maggioni, Eleonora, Fabbri, Chiara, Benedetti, Francesco, Vai, Benedetta

Source: In European Neuropsychopharmacology August 2024 85:45-57

The clinical perspective on late-onset depression in European real-world treatment settings

Authors: Bartova, Lucie, Fugger, Gernot, Dold, Markus, Kautzky, Alexander, Bairhuber, Isabella, Kloimstein, Philipp, Fanelli, Giuseppe, Zanardi, Raffaella, Weidenauer, Ana, Rujescu, Dan, Souery, Daniel, Mendlewicz, Julien, Zohar, Joseph, Montgomery, Stuart, Fabbri, Chiara, Serretti, Alessandro, Kasper, Siegfried

Source: In European Neuropsychopharmacology July 2024 84:59-68

Polygenic risk scores for mood and related disorders and environmental factors: Interaction effects on wellbeing in the UK biobank

Authors: Fabbri, Chiara, Lewis, Cathryn M., Serretti, Alessandro

Source: In Progress in Neuropsychopharmacology & Biological Psychiatry 8 June 2024 132

Pharmacological treatments for psychotic depression: a systematic review and network meta-analysis

Authors: Oliva, Vincenzo ^†, Possidente, Chiara ^†, De Prisco, Michele, Fico, Giovanna, Anmella, Gerard, Hidalgo-Mazzei, Diego, Murru, Andrea, Fanelli, Giuseppe, Fabbri, Chiara, Fornaro, Michele, de Bartolomeis, Andrea, Solmi, Marco, Radua, Joaquim, Vieta, Eduard ^*, Serretti, Alessandro

Source: In The Lancet Psychiatry March 2024 11(3):210-220

Biomarkers of treatment-resistant schizophrenia: A systematic review

Authors: Pisanu, Claudia, Severino, Giovanni, Minelli, Alessandra, Dierssen, Mara, Potier, Marie-Claude, Fabbri, Chiara, Serretti, Alessandro, Gennarelli, Massimo, Baune, Bernhard T., Squassina, Alessio

Source: In Neuroscience Applied 2024 3

Polygenic scores of subcortical brain volumes as possible modulators of treatment response in depression

Authors: Potier, Marie-Claude, van Westrhenen, Roos, Rybakowski, Filip, Mehta, Divya, Dierssen, Mara, Janzing, Joost G.E., Liò, Pietro, Oliva, Vincenzo, Martone, Alfonso, Fanelli, Giuseppe, Domschke, Katharina, Minelli, Alessandra, Gennarelli, Massimo, Martini, Paolo, Bortolomasi, Marco, Maron, Eduard, Squassina, Alessio, Pisanu, Claudia, Kasper, Siegfried, Zohar, Joseph, Souery, Daniel, Montgomery, Stuart, Albani, Diego, Forloni, Gianluigi, Ferentinos, Panagiotis, Rujescu, Dan, Mendlewicz, Julien, De Ronchi, Diana, Baune, Bernhard T., Serretti, Alessandro, Fabbri, Chiara

Source: In Neuroscience Applied 2024 3

Differences in facial emotion recognition between bipolar disorder and other clinical populations: A systematic review and meta-analysis

Authors: De Prisco, Michele ^{a, b, c, d, 1}, Oliva, Vincenzo ^{a, b, c, e, 1}, Fico, Giovanna ^{a, b, c}, Montejo, Laura ^{a, b, c, d}, Possidente, Chiara ^{b, c, e}, Bracco, Lorenzo ^{b, c, f}, Fortea, Lydia ^{a, g}, Anmella, Gerard ^{a, b, c}, Hidalgo-Mazzei, Diego ^{a, b, c}, Fornaro, Michele ^h, de Bartolomeis, Andrea ^h, Serretti, Alessandro ^e, Murru, Andrea ^{a, b, c}, Vieta, Eduard ^{a, b, c, d, ⁎}, Radua, Joaquim ^{d, g, i, j}

Source: In Progress in Neuropsychopharmacology & Biological Psychiatry 20 December 2023 127

Clinical insights into the cross-link between mood disorders and type 2 diabetes: A review of longitudinal studies and Mendelian randomisation analyses

Authors: Possidente, Chiara, Fanelli, Giuseppe, Serretti, Alessandro, Fabbri, Chiara

Source: In Neuroscience and Biobehavioral Reviews September 2023 152

Body mass index and clinical outcomes in individuals with major depressive disorder: Findings from the GSRD European Multicenter Database

Authors: Kraus, Christoph, Kautzky, Alexander, Watzal, Victoria, Gramser, Anna, Kadriu, Bashkim, Deng, Zhi-De, Bartova, Lucie, Zarate, Carlos A., Jr., Lanzenberger, Rupert, Souery, Daniel, Montgomery, Stuart, Mendlewicz, Julien, Zohar, Joseph, Fanelli, Giuseppe, Serretti, Alessandro, Kasper, Siegfried

Source: In Journal of Affective Disorders 15 August 2023 335:349-357

Real-world characteristics of European patients receiving SNRIs as first-line treatment for major depressive disorder

Authors: Bartova, Lucie, Fugger, Gernot, Dold, Markus, Kautzky, Alexander, Fanelli, Giuseppe, Zanardi, Raffaella, Albani, Diego, Weidenauer, Ana, Rujescu, Dan, Souery, Daniel, Mendlewicz, Julien, Montgomery, Stuart, Zohar, Joseph, Fabbri, Chiara, Serretti, Alessandro, Kasper, Siegfried

Source: In Journal of Affective Disorders 1 July 2023 332:105-114

Multi-omics data integration methods and their applications in psychiatric disorders

Authors: Sathyanarayanan, Anita, Mueller, Tamara T., Ali Moni, Mohammad, Schueler, Katja, Baune, Bernhard T., Lio, Pietro, Mehta, Divya, Baune, Bernhard T, Dierssen, Mara, Ebert, Bjarke, Fabbri, Chiara, Fusar-Poli, Paolo, Gennarelli, Massimo, Harmer, Catherine, Howes, Oliver D., Janzing, Joost G.E., Maron, Eduard, Minelli, Alessandra, Nonell, Lara, Pisanu, Claudia, Potier, Marie-Claude, Rybakowski, Filip, Serretti, Alessandro, Squassina, Alessio, Stacey, David, van Westrhenen, Roos, Xicota, Laura

Source: In European Neuropsychopharmacology April 2023 69:26-46

Melancholic features and typical neurovegetative symptoms of major depressive disorder show specific polygenic patterns

Authors: Oliva, Vincenzo, Fanelli, Giuseppe, Kasper, Siegfried, Zohar, Joseph, Souery, Daniel, Montgomery, Stuart, Albani, Diego, Forloni, Gianluigi, Ferentinos, Panagiotis, Rujescu, Dan, Mendlewicz, Julien, De Ronchi, Diana, Fabbri, Chiara, Serretti, Alessandro

Source: In Journal of Affective Disorders 1 January 2023 320:534-543

The link between cognition and somatic conditions related to insulin resistance in the UK Biobank study cohort: a systematic review

Authors: Fanelli, Giuseppe, Mota, Nina Roth, Salas-Salvadó, Jordi, Bulló, Mònica, Fernandez-Aranda, Fernando, Camacho-Barcia, Lucía, Testa, Giulia, Jiménez-Murcia, Susana, Bertaina-Anglade, Valérie, Franke, Barbara, Poelmans, Geert, van Gils, Veerle, Jansen, Willemijn J., Vos, Stephanie J.B., Wimberley, Theresa, Dalsgaard, Søren, Barta, Csaba, Serretti, Alessandro, Fabbri, Chiara, Bralten, Janita

Source: In Neuroscience and Biobehavioral Reviews December 2022 143