Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-κB signaling pathway mediated by the DNA damage response

Authors: Yu Ma, Siwen Li, Shuzi Ye, Die Hu, Lai Wei, Fang Xiao

Source: Ecotoxicology and Environmental Safety, Vol 239, Iss , Pp 113645- (2022)

Subject Terms: Hexavalent chromium [Cr(VI)], Senescence-associated secretion phenotype (SASP), Premature senescence, Zinc finger transcription factor GATA4, Nuclear factor kappa-B (NF-κB), Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651322004857; https://doaj.org/toc/0147-6513

Access URL: https://doaj.org/article/52fa88b1b863421484b8bcae45f0c6ef

Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium

Authors: Yu Ma, Yuehui Liang, Ningjuan Liang, Yujing Zhang, Fang Xiao

Source: Ecotoxicology and Environmental Safety, Vol 211, Iss , Pp 111908- (2021)

Subject Terms: Hexavalent chromium [Cr(VI)], Premature senescence, Senescence-associated secretion phenotype (SASP), Alpha-enolase (ENO1), Peroxiredoxin 2 (PRDX2), Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651321000191; https://doaj.org/toc/0147-6513

Access URL: https://doaj.org/article/97ff78f749274e08bc9e48ea9a824035