Autologous Human Dendritic Cells from XDR-TB Patients Polarize a Th1 Response Which Is Bactericidal to Mycobacterium tuberculosis.

Authors: Londt, Rolanda, Semple, Lynn, Esmail, Aliasgar, Pooran, Anil, Meldau, Richard, Davids, Malika, Dheda, Keertan, Tomasicchio, Michele

Source: Microorganisms; Feb2025, Vol. 13 Issue 2, p345, 31p

Subject Terms: MONONUCLEAR leukocytes, PEPTIDES, MYCOBACTERIUM tuberculosis, PUBLIC health, DENDRITIC cells

The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis –Specific Host Immunity Through the Glucocorticoid Receptor

Authors: Tomasicchio, Michele, Davids, Malika, Pooran, Anil, Theron, Grant, Smith, Liezel, Semple, Lynn, Meldau, Richard, Hapgood, Janet Patricia, Dheda, Keertan

Source: The Journal of Infectious Diseases, 2019 Apr . 219(8), 1329-1337.

Access URL: https://www.jstor.org/stable/26634030

SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset.

Authors: Tomasicchio, Michele, Jaumdally, Shameem, Wilson, Lindsay, Kotze, Andrea, Semple, Lynn, Meier, Stuart, Pooran, Anil, Esmail, Aliasgar, Pillay, Komala, Roberts, Riyaadh, Kriel, Raymond, Meldau, Richard, Oelofse, Suzette, Mandviwala, Carley, Burns, Jessica, Londt, Rolanda, Davids, Malika, van der Merwe, Charnay, Roomaney, Aqeedah, Kühn, Louié

Source: American Journal of Respiratory & Critical Care Medicine; 4/1/2024, Vol. 209 Issue 7, p840-851, 12p

Subject Terms: SARS-CoV-2, CORONAVIRUS diseases, VIRAL replication, BETA rhythm

An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells.

Authors: Tomasicchio, Michele¹, Semple, Lynn¹, Esmail, Aliasgar¹, Meldau, Richard¹, Randall, Philippa¹, Pooran, Anil¹, Davids, Malika¹, Cairncross, Lydia², Anderson, David³, Downs, Jennifer², Malherbe, Francois², Novitzky, Nicolas^4,5, Panieri, Eugenio², Oelofse, Suzette¹, Londt, Rolanda¹, Naiker, Thurandrie², Dheda, Keertan^1,6 keertan.dheda@uct.ac.za

Source: Cancer Immunology, Immunotherapy. Jan2019, Vol. 68 Issue 1, p71-83. 13p.

Subject Terms: *BREAST cancer, *DENDRITIC cells, *CANCER cells, *CELLS, *T cells

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Authors: Alexander, Sue, Bostock, Jansen, Conroy, Ian, Day, Gwyneth, Brown, Sharon, Plant, Helen, Taylor, Rosie, Johnson, Ian, Cartmell, Warren, King, Gary, Dory Glasson, Hayley, Semple, Lynn, Pitches, Melanie, Whittle, Sparky, Smith, Rachel, Johnstone, Jimmy, Thomas, Nick

Source: H2Open; Feb/Mar2016, Issue 33, p26-27, 2p, 7 Color Photographs

Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-gamma.

Authors: Kampmann, Beate, Hemingway, Cheryl, Stephens, Alick, Davidson, Robert, Goodsall, Anna, Anderson, Suzanne, Nicol, Mark, Schölvinck, Elisabeth, Relman, David, Waddell, Simon, Langford, Paul, Sheehan, Brian, Semple, Lynn, Wilkinson, Katalin A., Wilkinson, Robert J., Ress, Stanley, Hibberd, Martin, Levin, Michael, Schölvinck, Elisabeth (AUTHOR)

Source: Journal of Clinical Investigation. Sep2005, Vol. 115 Issue 9, p2480-2488. 9p. 1 Chart, 5 Graphs.

Subjects: MYCOBACTERIAL diseases, BACTERIAL diseases, PATHOGENIC microorganisms, ACTINOMYCETALES, NUCLEAR spectroscopy, SPECTRUM analysis, MONONUCLEAR leukocytes, AUTOANTIBODIES, DISEASE susceptibility, GENES, INTERFERONS, MACROPHAGES, RESEARCH funding, TUMOR necrosis factors, HLA-B27 antigen, OLIGONUCLEOTIDE arrays, GENE expression profiling, PHYSIOLOGY