THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Authors: Alexander, Stephen P H, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria Pia, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Bathgate, Ross, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel J.M., Blaho, Victoria, Boulay, Francois, Bousquet, Corinne, Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P., Catt, Kevin J., Ceruti, Stefania, Chazot, Paul, Chiang, Nan, Chini, Bice, Chun, Jerold, Cianciulli, Antonia, Civelli, Olivier, Clapp, Lucie H., Couture, Réjean, Csaba, Zsolt, Dahlgren, Claes, Dent, Gordon, Singh, Khuraijam Dhanachandra, Douglas, Steven D., Dournaud, Pascal, Eguchi, Satoru, Escher, Emanuel, Filardo, Edward J., Fong, Tung, Fumagalli, Marta, Gainetdinov, Raul R, Gasparo, Marc de, Gerard, Craig, Gershengorn, Marvin, Gobeil, Fernand, Goodfriend, Theodore L., Goudet, Cyril, Gregory, Karen J., Gundlach, Andrew L., Hamann, Jörg, Hanson, Julien, Hauger, Richard L., Hay, Debbie L., Heinemann, Akos, Hollenberg, Morley D., Holliday, Nicholas D., Horiuchi, Mastgugu, Hoyer, Daniel, Hunyady, László, Husain, Ahsan, IJzerman, Adriaan P., Inagami, Tadashi, Jacobson, Kenneth A., Jensen, Robert T., Jockers, Ralf, Jonnalagadda, Deepa, Karnik, Sadashiva, Kaupmann, Klemens, Kemp, Jacqueline, Kennedy, Charles, Kihara, Yasuyuki, Kitazawa, Takio, Kozielewicz, Pawel, Kreienkamp, Hans‐Jürgen, Kukkonen, Jyrki P., Langenhan, Tobias, Leach, Katie, Lecca, Davide, Lee, John D., Leeman, Susan E., Leprince, Jérôme, Li, Xaria X., Williams, Tom Lloyd, Lolait, Stephen J., Lupp, Amelie, Macrae, Robyn, Maguire, Janet, Mazella, Jean, McArdle, Craig A., Melmed, Shlomo, Michel, Martin C., Miller, Laurence J., Mitolo, Vincenzo, Mouillac, Bernard, Müller, Christa E., Murphy, Philip, Nahon, Jean‐Louis, Ngo, Tony, Norel, Xavier, Nyimanu, Duuamene, O'Carroll, Anne‐Marie, Offermanns, Stefan, Panaro, Maria Antonietta, Parmentier, Marc, Pertwee, Roger G., Pin, Jean‐Philippe, Prossnitz, Eric R., Quinn, Mark, Ramachandran, Rithwik, Ray, Manisha, Reinscheid, Rainer K., Rondard, Philippe, Rovati, G. Enrico, Ruzza, Chiara, Sanger, Gareth J., Schöneberg, Torsten, Schulte, Gunnar, Schulz, Stefan, Segaloff, Deborah L., Serhan, Charles N., Stoddart, Leigh A., Sugimoto, Yukihiko, Summers, Roger, Tan, Valerie P., Thal, David, Thomas, Walter (Wally), Timmermans, Pieter B. M. W. M., Tirupula, Kalyan, Tulipano, Giovanni, Unal, Hamiyet, Unger, Thomas, Valant, Celine, Vanderheyden, Patrick, Vaudry, David, Vaudry, Hubert, Vilardaga, Jean‐Pierre, Walker, Christopher S., Wang, Ji Ming, Ward, Donald T., Wester, Hans‐Jürgen, Willars, Gary B, Woodruff, Trent M., Yao, Chengcan, Ye, Richard D.

Source: British journal of pharmacology. 178:S27-S156

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140911703.0x000001&indx=1&recIds=ETOCvdc_100140911703.0x000001

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors

Authors: Alexander, Stephen P H, Christopoulos, Arthur, Davenport, Anthony P, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Abbracchio, Maria P, Alexander, Wayne, Al-hosaini, Khaled, Bäck, Magnus, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Bettler, Bernhard, Birdsall, Nigel JM, Blaho, Victoria, Bousquet, Corinne, Bräuner-Osborne, Hans, Burnstock, Geoffrey, Caló, Girolamo, Castaño, Justo P, Catt, Kevin J, Ceruti, Stefania, Chazot, Paul, Chiang, Nan, Chun, Jerold, Cianciulli, Antonia, Clapp, Lucie H, Couture, Réjean, Csaba, Zsolt, Dent, Gordon, Singh, Khuraijam Dhanachandra, Douglas, Steven D, Dournaud, Pascal, Eguchi, Satoru, Escher, Emanuel, Filardo, Edward, Fong, Tung M, Fumagalli, Marta, Gainetdinov, Raul R, Gasparo, Marc de, Gershengorn, Marvin, Gobeil, Fernand, Goodfriend, Theodore L, Goudet, Cyril, Gregory, Karen J, Gundlach, Andrew L, Hamann, Jörg, Hanson, Julien, Hauger, Richard L, Hay, Debbie, Heinemann, Akos, Hollenberg, Morley D, Holliday, Nicholas D, Horiuchi, Mastgugu, Hoyer, Daniel, Hunyady, László, Husain, Ahsan, Ijzerman, Adriaan P, Inagami, Tadashi, Jacobson, Kenneth A, Jensen, Robert T, Jockers, Ralf, Jonnalagadda, Deepa, Karnik, Sadashiva, Kaupmann, Klemens, Kemp, Jacqueline, Kennedy, Charles, Kihara, Yasuyuki, Kozielewicz, Paweł, Kreienkamp, Hans‐Jürgen, Kukkonen, Jyrki P, Langenhan, Tobias, Leach, Katie, Lecca, Davide, Lee, John D, Leeman, Susan E, Leprince, Jérôme, Lolait, Stephen J, Lupp, Amelie, Macrae, Robyn, Maguire, Janet, Mazella, Jean, McArdle, Craig A, Melmed, Shlomo, Michel, Martin C, Miller, Laurence, Mitolo, Vincenzo, Mouillac, Bernard, Murphy, Philip M, Nahon, Jean‐Louis, Norel, Xavier, Nyimanu, Duuamene, O'Carroll, Anne‐Marie, Offermanns, Stefan, Panaro, Maria A, Pertwee, Roger G, Pin, Jean‐Philippe, Prossnitz, Eric, Ramachandran, Rithwik, Reinscheid, Rainer K, Rondard, Philippe, Rovati, G Enrico, Ruzza, Chiara, Sanger, Gareth, Schöneberg, Torsten, Schulte, Gunnar, Schulz, Stefan, Segaloff, Deborah L, Serhan, Charles N, Stoddart, Leigh A, Sugimoto, Yukihiko, Summers, Roger, Tan, Valerie, Thomas, Walter, Timmermans, Pieter BMWM, Tirupula, Kalyan, Tulipano, Giovanni, Unal, Hamiyet, Unger, Thomas, Vanderheyden, Patrick, Vaudry, David, Vaudry, Hubert, Vilardaga, Jean‐Pierre, Walker, Christopher S, Ward, Donald T, Wester, Hans‐Jürgen, Willars, Gary B, Williams, Tom Lloyd, Woodruff, Trent M, Yao, Chengcan

Source: British journal of pharmacology. 176:S21-S141

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093528182.0x000001&indx=1&recIds=ETOCvdc_100093528182.0x000001

FSH Actions and Pregnancy: Looking Beyond Ovarian FSH Receptors

Authors: Stilley, Julie A W, Segaloff, Deborah L

Source: Endocrinology. 159(12):4033-4042

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100078390549.0x000001&indx=1&recIds=ETOCvdc_100078390549.0x000001

Deletion of fetoplacental Fshr inhibits fetal vessel angiogenesis in the mouse placenta

Authors: Stilley, Julie A.W., Segaloff, Deborah L.

Source: Molecular and cellular endocrinology. 476:79-83

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100066389942.0x000001&indx=1&recIds=ETOCvdc_100066389942.0x000001

Rescue of expression and signaling of human luteinizing hormone G protein-coupled receptor mutants with an allosterically binding small-molecule agonist

Authors: Newton, Claire L., Whay, Adele M., McArdle, Craig A., Zhang, Meilin, van Koppen, Chris J., van de Lagemaat, Ruud, Segaloff, Deborah L., Millar, Robert P., Vale, Wylie W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2011 Apr . 108(17), 7172-7176.

Access URL: https://www.jstor.org/stable/41242148

Structural determinants underlying constitutive dimerization of unoccupied human follitropin receptors

Authors: Guan, Rongbin, Wu, Xueqing, Feng, Xiuyan, Zhang, Meilin, Hébert, Terence E., Segaloff, Deborah L.

Source: In Cellular Signalling February 2010 22(2):247-256

Bioluminescence Resonance Energy Transfer Studies Reveal Constitutive Dimerization of the Human Lutropin Receptor and a Lack of Correlation between Receptor Activation and the Propensity for Dimerization

Authors: Guan, Rongbin, Feng, Xiuyan, Wu, Xueqing, Zhang, Meilin, Zhang, Xuesen, Hébert, Terence E., Segaloff, Deborah L.

Source: In Journal of Biological Chemistry 20 March 2009 284(12):7483-7494

A cell surface inactive mutant of the human lutropin receptor (hLHR) attenuates signaling of wild-type or constitutively active receptors via heterodimerization

Authors: Zhang, Meilin, Feng, Xiuyan, Guan, Rongbin, Hébert, Terence E., Segaloff, Deborah L.

Source: In Cellular Signalling 2009 21(11):1663-1671

Chapter 4 Diseases Associated with Mutations of the Human Lutropin Receptor

Authors: Segaloff, Deborah L.

Source: In Progress in Molecular Biology and Translational Science 2009 89:97-114

Chapter 5 Follicle Stimulating Hormone Receptor Mutations and Reproductive Disorders

Authors: Tao, Ya-Xiong ^*, Segaloff, Deborah L.

Source: In Progress in Molecular Biology and Translational Science 2009 89:115-131

Lutropin-Choriogonadotropin Receptor: An Unusual Member of the G Protein--Coupled Receptor Family

Authors: McFarland, K. C., Sprengel, Rolf, Phillips, Heidi S., Köhler, Martin, Rosemblit, Nora, Nikolics, Karoly, Segaloff, Deborah L., Seeburg, Peter H.

Source: Science, 1989 Aug 01. 245(4917), 494-499.

Access URL: https://www.jstor.org/stable/1704078

Luteinizing Hormone Receptor Appearance in Cultured Porcine Granulosa Cells Requires Continual Presence of Follicle-Stimulating Hormone

Authors: Segaloff, Deborah L., Limbird, Lee E.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1983 Sep . 80(18), 5631-5635.

Access URL: https://www.jstor.org/stable/14393

Intrinsic Differences in the Response of the Human Lutropin Receptor Versus the Human Follitropin Receptor to Activating Mutations

Authors: Zhang, Meilin, Tao, Ya-Xiong, Ryan, Ginny L., Feng, Xiuyan, Fanelli, Francesca, Segaloff, Deborah L.

Source: In Journal of Biological Chemistry 31 August 2007 282(35):25527-25539

Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor

Authors: Latronico, Ana Claudia, Segaloff, Deborah L.

Source: In Molecular and Cellular Endocrinology 2 January 2007 260-262:287-293

Glycoprotein hormone receptor molecules

The Formation of a Salt Bridge Between Helices 3 and 6 Is Responsible for the Constitutive Activity and Lack of Hormone Responsiveness of the Naturally Occurring L457R Mutation of the Human Lutropin Receptor

Authors: Zhang, Meilin ^{‡, §}, Mizrachi, Dario ^‡, Fanelli, Francesca ^{¶, ∥}, Segaloff, Deborah L. ^{‡, **}

Source: In Journal of Biological Chemistry 15 July 2005 280(28):26169-26176

Thyroid-Stimulating Hormone/Luteinizing Hormone/Follicle-Stimulating Hormone Receptors

Authors: Segaloff, Deborah L, Mizrachi, Dario, Ascoli, Mario

Source: Encyclopedia of Biological Chemistry. 2004, v. 4, p180-186.

Subject Terms: Gene expression, Follicle-stimulating hormone, Hormone receptors, Gene mutation, Luteinizing hormone, Thyrotropin

Luteinizing hormone/choriogonadotropin (LH/CG) receptor

Constitutive and Agonist-dependent Self-association of the Cell Surface Human Lutropin Receptor

Authors: Tao, Ya-Xiong ^{*, ‡}, Johnson, Nathan B. ^*, Segaloff, Deborah L. ^{*, §}

Source: In Journal of Biological Chemistry 13 February 2004 279(7):5904-5914

Naturally Occurring Mutations of the Luteinizing-Hormone Receptor: Lessons Learned about Reproductive Physiology and G Protein–Coupled Receptors

Authors: Latronico, Ana Claudia, Segaloff, Deborah L.

Source: In The American Journal of Human Genetics 1999 65(4):949-958