Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours

Authors: Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A. Oldridge, Sumedha Sudhaman, Kelsey Zhu, S. Y. Cindy Yang, David T. Mulder, Jeffrey P. Bruce, Joseph N. Paulson, Pichai Raman, Yuankun Zhu, Adam C. Resnick, Poul H. Sorensen, Martin Sill, Sebastian Brabetz, Sander Lambo, David Malkin, Pascal D. Johann, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Natalie Jäger, Trevor J. Pugh

Source: Genome Medicine, Vol 15, Iss 1, Pp 1-24 (2023)

Subject Terms: Paediatric neuro-oncology, Immunogenomics, CNS tumours, Tumour microenvironment, Neuroblastoma, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/55f18503cc5b446bb5969c8df01fb686

977 Development of a non-small cell lung cancer PDX model in a myeloid-boosted humanized host highlights a M2 polarization phenotype within the myeloid compartment

Authors: Stefano Cairo, Mara Gilardi, Brandon Walling, Marianna Zipeto, Alex Moreau, Kiave Yune Ho Wang Yin, Nektaria Papadopoulou, Sebastian Brabetz, David DeOrnellis

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/b8f57b3703c1429e8b58dc146066e335

Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion

Authors: Yulun Huang, Lin Qi, Mari Kogiso, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Sophie Xiao, Wan‐Yee Teo, Holly Lindsay, Sibo Zhao, Patricia Baxter, Jack M. F. Su, Adekunle Adesina, Jianhua Yang, Sebastian Brabetz, Marcel Kool, Stefan M. Pfister, Murali Chintagumpala, Laszlo Perlaky, Zhong Wang, Youxin Zhou, Tsz‐Kwong Man, Xiao‐Nan Li

Source: Advanced Science, Vol 8, Iss 23, Pp n/a-n/a (2021)

Subject Terms: 4‐aminopyridine, glioblastoma, KCNA1, miRNA, patient derived orthotopic xenograft, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/d951663ff7d440bebd6494e2644f1aa3

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

Authors: Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, Sebastian Brabetz, Laura Sieber, Melissa Gulley, Monika Mauermann, Tatjana Wedig, Norman Mack, Yuka Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, Felipe Andreiuolo, Eric Holland, Kendra Maass, Huiqin Körkel-Qu, Hai-Kun Liu, Felix Sahm, David Capper, Jens Bunt, Linda J. Richards, David T. W. Jones, Andrey Korshunov, Lukas Chavez, Peter Lichter, Mikio Hoshino, Stefan M. Pfister, Marcel Kool, Wei Li, Daisuke Kawauchi

Source: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/adf1b461d84d45cc809ee416ce32b241