ReCLAIM-2: A Randomized Phase II Clinical Trial Evaluating Elamipretide in Age-related Macular Degeneration, Geographic Atrophy Growth, Visual Function, and Ellipsoid Zone Preservation

Authors: Justis P. Ehlers, MD, Allen Hu, MD, David Boyer, MD, Scott W. Cousins, MD, Nadia K. Waheed, MD, Philip J. Rosenfeld, MD, PhD, David Brown, MD, Peter K. Kaiser, MD, Anthony Abbruscato, PharmD, Gui Gao, PhD, Jeffrey Heier, MD, Prema Abraham, Christopher Devine, Anita Schadlu, George Novalis, Derek Y. Kunimoto, John Parchue, Suk Jin Moon, Zachary Segal, Dennis Marcus, Paul Hahn, Eric Suan, Michael Lee, Victor Gonzalez, Michael A. Samuel, Sunil Patel, Patrick Williams, Brian B. Berger, Henry Kwong, Dante Pieramici, Eric W. Schneider, Yevgeniy Shildkrot, Mathew T. Witmer, Nathan Steinle, Carmelina Gordon, Daniel Learned, Patrick Higgins, Guruprasad Pattar, Vijay Khetpal, Robin Ross, Mark R. Barakat, Sun Young Lee Sjatkowski, David Lally, Troy Becker

Source: Ophthalmology Science, Vol 5, Iss 1, Pp 100628- (2025)

Subject Terms: Age-related macular degeneration, Elamipretide, Ellipsoid zone, Geographic atrophy, Visual acuity, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666914524001647; https://doaj.org/toc/2666-9145

Access URL: https://doaj.org/article/7164fb5412894bafbf1cb11d512f531f

Phase 1 Clinical Trial of Elamipretide in Intermediate Age-Related Macular Degeneration and High-Risk Drusen

Authors: Michael J. Allingham, MD, PhD, Priyatham S. Mettu, MD, Scott W. Cousins, MD

Source: Ophthalmology Science, Vol 2, Iss 1, Pp 100095- (2022)

Subject Terms: Dry age-related macular degeneration, Elamipretide, Mitochondrial dysfunction, Phase 1 clinical trial, Retina, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666914521000907; https://doaj.org/toc/2666-9145

Access URL: https://doaj.org/article/564ea67338bb440da4473a2951dec362

Phase 1 Clinical Trial of Elamipretide in Dry Age-Related Macular Degeneration and Noncentral Geographic Atrophy

Authors: Priyatham S. Mettu, MD, Michael J. Allingham, MD, PhD, Scott W. Cousins, MD

Source: Ophthalmology Science, Vol 2, Iss 1, Pp 100086- (2022)

Subject Terms: Dry age-related macular degeneration, Elamipretide, Geographic atrophy, Mitochondrial dysfunction, Phase 1 clinical trial, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666914521000889; https://doaj.org/toc/2666-9145

Access URL: https://doaj.org/article/06ec418bb89643339039f47dbed8de5b