Human ACE2 transgenic pigs are susceptible to SARS-CoV-2 and develop COVID-19-like disease

Authors: Long Fung Chau, Simon Lillico, Tanja Opriessnig, Rosemary Blake, Luc Tardy, Chen-Hsuin Lee, Scott Maxwell, Claire Warren, Elizabeth Thornton, Catherine L. Mclaughlin, Gerry McLachlan, Christine Tait-Burkard, Sarah Fletcher, Stephen Anderson, Sharon Brown, Louise Gibbard, Thomas Tzelos, Dawn MacMillan-Christensen, J. Kenneth Baillie, David A. Dorward, David J. Griffiths, Finn Grey

Source: Nature Communications, Vol 16, Iss 1, Pp 1-13 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/220f8661bc3f4356b90c5f01f6558ea4

EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors

Authors: Keith Al-Hasani, Safiya Naina Marikar, Harikrishnan Kaipananickal, Scott Maxwell, Jun Okabe, Ishant Khurana, Thomas Karagiannis, Julia J. Liang, Lina Mariana, Thomas Loudovaris, Thomas Kay, Assam El-Osta

Source: Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/a14c0d5910f4469ba3b5e5607fe3fe80

Supervised smoking facility access, harm reduction practices, and substance use changes during the COVID-19 pandemic: a community-engaged cross-sectional study

Authors: Jenna van Draanen, Jonah Hamilton, Jeffrey Morgan, Scott Maxwell, Tara Taylor, Lindsey Richardson, Seonaid Nolan

Source: Harm Reduction Journal, Vol 20, Iss 1, Pp 1-10 (2023)

Subject Terms: Supervised inhalation site, Supervised consumption site, Overdose prevention, Poisoning, Harm reduction, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1477-7517

Access URL: https://doaj.org/article/41d0086616444172b30af617d229693e

Pharmacological inhibition of human EZH2 can influence a regenerative β-like cell capacity with in vitro insulin release in pancreatic ductal cells

Authors: Safiya Naina Marikar, Keith Al-Hasani, Ishant Khurana, Harikrishnan Kaipananickal, Jun Okabe, Scott Maxwell, Assam El-Osta

Source: Clinical Epigenetics, Vol 15, Iss 1, Pp 1-15 (2023)

Subject Terms: Islet, Pancreas, Ductal cells, Regenerative capacity, Histone modification, EZH2, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/f768a6415bfc4ac8bcef572e3bf4fbf6

Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor

Authors: Keith Al-Hasani, Ishant Khurana, Lina Mariana, Thomas Loudovaris, Scott Maxwell, K. N. Harikrishnan, Jun Okabe, Mark E. Cooper, Assam El-Osta

Source: Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-9 (2022)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/f66d28f2b6e44e479456526aaa0db345

Reduced methylation correlates with diabetic nephropathy risk in type 1 diabetes

Authors: Ishant Khurana, Harikrishnan Kaipananickal, Scott Maxwell, Sørine Birkelund, Anna Syreeni, Carol Forsblom, Jun Okabe, Mark Ziemann, Antony Kaspi, Haloom Rafehi, Anne Jørgensen, Keith Al-Hasani, Merlin C. Thomas, Guozhi Jiang, Andrea O.Y. Luk, Heung Man Lee, Yu Huang, Yotsapon Thewjitcharoen, Soontaree Nakasatien, Thep Himathongkam, Christopher Fogarty, Rachel Njeim, Assaad Eid, Tine Willum Hansen, Nete Tofte, Evy C. Ottesen, Ronald C.W. Ma, Juliana C.N. Chan, Mark E. Cooper, Peter Rossing, Per-Henrik Groop, Assam El-Osta

Source: The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)

Subject Terms: Metabolism, Nephrology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/64117e1fe4b8440bb9cf852ef9a65858

SAHA attenuates Takotsubo-like myocardial injury by targeting an epigenetic Ac/Dc axis

Authors: Ishant Khurana, Scott Maxwell, Simon Royce, Prabhu Mathiyalagan, Tom Karagiannis, Nadia Mazarakis, Jitraporn Vongsvivut, Harikrishnan K.N., Jun Okabe, Keith Al-Hasani, Chrishan Samuel, Assam El-Osta

Source: Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-4 (2021)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/fbe903d8f165458c810ab382457441f0

DNA methylation status correlates with adult β-cell regeneration capacity

Authors: Ishant Khurana, Keith Al-Hasani, Scott Maxwell, Harikrishnan K.N., Jun Okabe, Mark E. Cooper, Patrick Collombat, Assam El-Osta

Source: npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-5 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3995

Access URL: https://doaj.org/article/7002e532a015471484dce7a5ddb7656f

Valproic acid influences the expression of genes implicated with hyperglycaemia-induced complement and coagulation pathways

Authors: Marina Barreto Felisbino, Mark Ziemann, Ishant Khurana, Jun Okabe, Keith Al-Hasani, Scott Maxwell, K. N. Harikrishnan, Camila Borges Martins de Oliveira, Maria Luiza S. Mello, Assam El-Osta

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/003e0b1330af43baa6106c9dd0f31214

The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa

Authors: Jorge del-Pozo, Denis J. Headon, James D. Glover, Ali Azar, Sonia Schuepbach-Mallepell, Mahmood F. Bhutta, Jon Riddell, Scott Maxwell, Elspeth Milne, Pascal Schneider, Michael Cheeseman

Source: Disease Models & Mechanisms, Vol 15, Iss 3 (2022)

Subject Terms: hypohidrotic ectodermal dysplasia, sparse and wavy hair rat, edaradd, fbxo11, mecom, edar, tabby mouse, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/15/3/dmm049034; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/6efcf17ea4b6497ab37681047ef17eb8

Prolonged Honeymoon Period in a Thai Patient with Adult-Onset Type 1 Diabetes Mellitus

Authors: Yotsapon Thewjitcharoen, Ekgaluck Wanothayaroj, Haruethai Jaita, Soontaree Nakasatien, Siriwan Butadej, Ishant Khurana, Scott Maxwell, Assam El-Osta, Waralee Chatchomchuan, Sirinate Krittiyawong, Thep Himathongkam

Source: Case Reports in Endocrinology, Vol 2021 (2021)

Subject Terms: Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/2090-6501; https://doaj.org/toc/2090-651X

Access URL: https://doaj.org/article/ef735a0c924e4212b9b699f2b026091c

MeCP2 interacts with chromosomal microRNAs in brain

Authors: Abdul Waheed Khan, Mark Ziemann, Haloom Rafehi, Scott Maxwell, Giuseppe D. Ciccotosto, Assam El-Osta

Source: Epigenetics, Vol 12, Iss 12, Pp 1028-1037 (2017)

Subject Terms: mecp2, micrornas, rna-chromatin immunoprecipitation, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/7cf7cb77463c4d71bfad5159b21e81e6

Identification of a gene promoter active in Lucilia sericata larval salivary glands using a rapid transient expression assay

Authors: Belikoff, Esther J., Davis, Rebecca J., Williamson, Megan E., Britt, John W., Scott, Maxwell J.

Source: In Insect Biochemistry and Molecular Biology October 2024 173

Developmental plasticity and the evolution of parasitism in an unusual nematode, Parastrongyloides trichosuri

Authors: Stasiuk Susan J, Scott Maxwell J, Grant Warwick N

Source: EvoDevo, Vol 3, Iss 1, p 1 (2012)

Subject Terms: Evolution, QH359-425

File Description: electronic resource

Relation: http://www.evodevojournal.com/content/3/1/1; https://doaj.org/toc/2041-9139

Access URL: https://doaj.org/article/25a8ec07ad034859994da3693191c604

Early Surgical Treatment of Thoracolumbar Fractures With Thoracolumbar Injury Classification and Severity Scores Less Than 4

Authors: Lucasti, Christopher, Scott, Maxwell M., Slowinski, Joshua, Maraschiello, Mark, Clark, Lindsey D., Kowalski, Joseph M.

Source: Journal of the American Academy of Orthopaedic Surgeons. 31(9):e481-e488

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193351640.0x000001&indx=1&recIds=ETOCvdc_100193351640.0x000001

Development of transgenic corn planthopper Peregrinus maidis that express the tetracycline transactivator

Authors: Patil, Anandrao A., Klobasa, William, Espinoza‐Rivera, Dina, Baars, Oliver, Lorenzen, Marcé D., Scott, Maxwell J.

Source: Insect molecular biology. 32(4):363-375

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186842249.0x000001&indx=1&recIds=ETOCvdc_100186842249.0x000001

Insulated piggyBac vectors for insect transgenesis

Authors: Horn Carsten, Li Xuelei, Heinrich Jörg C, Belikoff Esther J, Atapattu Asela, Sarkar Abhimanyu, Wimmer Ernst A, Scott Maxwell J

Source: BMC Biotechnology, Vol 6, Iss 1, p 27 (2006)

Subject Terms: Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.biomedcentral.com/1472-6750/6/27; https://doaj.org/toc/1472-6750

Access URL: https://doaj.org/article/c1d8859a5ed54e7abddc57ba92c1901c

CRISPR/Cas9 Genome Editing in the New World Screwworm and Australian Sheep Blowfly

Authors: Paulo, Daniel F., Williamson, Megan E., Scott, Maxwell J.

Source: Methods in molecular biology. 2495:173-202

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629528865&indx=1&recIds=ETOCRN629528865

Does Surgical Day of the Week Affect Hospital Course and Outcomes for Patients Undergoing Adult Spinal Deformity Surgery?

Authors: Graham, Benjamin C, Lucasti, Christopher, Scott, Maxwell M, Baker, Seth C, Vallee, Emily K, Patel, Dil V, Hamill, Christopher L

Source: Global Spine Journal; Mar2025, Vol. 15 Issue 2, p1136-1142, 7p

Subject Terms: LENGTH of stay in hospitals, PATIENT readmissions, INPATIENT care, SPINAL surgery, COHORT analysis, SURGICAL complications

Development and testing of a novel killer–rescue self-limiting gene drive system in Drosophila melanogaster

Authors: Webster, Sophia H., Vella, Michael R., Scott, Maxwell J.

Source: Proceedings: Biological Sciences, 2020 Apr . 287(1925), 1-9.

Access URL: https://www.jstor.org/stable/27096292