Differences in IgG autoantibody Fab glycosylation across autoimmune diseases

Authors: Koers, Jana, Sciarrillo, Rocco, Derksen, Ninotska I.L., Vletter, Esther M., Fillié-Grijpma, Yvonne E., Raveling-Eelsing, Elisabeth, Graça, Nuno A.G., Leijser, Thiemo, Pas, Hendri H., Laura van Nijen-Vos, L., Braham, Maaike V.J., Buisman, Anne-Marie, de Jong, Jan, Schriek, Angela I., Tio-Gillen, Anne P., Teng, Y.K. Onno, Steenhuis, Maurice, Swaneveld, Francis H., de Taeye, Steven W., van Gils, Marit J., Verschuuren, Jan J.G.M., Rutgers, Bram, Heeringa, Peter, Horváth, Barbara, Jacobs, Bart C., de Leeuw, Karina, Franssen, Casper F.M., Veyradier, Agnès, Coppo, Paul, Gelderman, Kyra A., Marieke van Ham, S., van Els, Cécile A.C.M., van der Woude, Diane, Huizinga, Ruth, Huijbers, Maartje G., Kuijpers, Taco W., Toes, Rene E.M., Bos, Nicolaas A., Rispens, Theo

Source: In The Journal of Allergy and Clinical Immunology June 2023 151(6):1646-1654

Comprehensive overview of autoantibody isotype and subclass distribution

Authors: Volkov, Mikhail, Coppola, Mariateresa, Huizinga, Ruth, Eftimov, Filip, Huizinga, Tom W.J., van der Kooi, Anneke J., Oosten, Liesbeth E.M., Raaphorst, Joost, Rispens, Theo, Sciarrillo, Rocco, Titulaer, Maarten J., Wieske, Luuk, Toes, René E.M., Huijbers, Maartje G.M., van Schie, Karin A., van der Woude, Diane

Source: In The Journal of Allergy and Clinical Immunology November 2022 150(5):999-1010

SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia

Authors: van der Werf, Inge, Wojtuszkiewicz, Anna, Yao, Huilan, Sciarrillo, Rocco, Meggendorfer, Manja, Hutter, Stephan, Walter, Wencke, Janssen, Jeroen, Kern, Wolfgang, Haferlach, Claudia, Haferlach, Torsten, Jansen, Gerrit, Kaspers, Gertjan J. L., Groen, Richard, Ossenkoppele, Gert, Cloos, Jacqueline

Source: Leukemia. 35(9):2698-2702

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193005531.0x000001&indx=1&recIds=ETOCvdc_100193005531.0x000001

The role of alternative splicing in cancer: From oncogenesis to drug resistance

Authors: Sciarrillo, Rocco, Wojtuszkiewicz, Anna, Assaraf, Yehuda G., Jansen, Gerrit, Kaspers, Gertjan J.L., Giovannetti, Elisa, Cloos, Jacqueline ^*

Source: In Drug Resistance Updates December 2020 53

Exploring Splicing Modulation as an Innovative Approach to Combat Pancreatic Cancer: SF3B1 Emerges as a Prognostic Indicator and Therapeutic Target.

Authors: Sciarrillo, Rocco, Terrana, Francesca, Comandatore, Annalisa, Supadmanaba, I. Gede Putu, Bing Wang, El Hassouni, Btissame, Mantini, Giulia, Jansen, Gerrit, Avan, Amir, Carbone, Daniela, Diana, Patrizia, Peters, Godefridus J., Morelli, Luca, Cloos, Jacqueline, Assaraf, Yehuda G., Giovannetti, Elisa

Source: International Journal of Biological Sciences; 2024, Vol. 20 Issue 9, p3173-3184, 12p

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma

Authors: Sciarrillo, Rocco, Wojtuszkiewicz, Anna, El Hassouni, Btissame, Funel, Niccola, Gandellini, Paolo, Lagerweij, Tonny, Buonamici, Silvia, Blijlevens, Maxime, Zeeuw van der Laan, Eveline A., Zaffaroni, Nadia, Deraco, Marcello, Kusamura, Shigeki, Würdinger, Tom, Peters, Godefridus J., Molthoff, Carla F.M., Jansen, Gerrit, Kaspers, Gertjan J.L., Cloos, Jacqueline, Giovannetti, Elisa

Source: In EBioMedicine January 2019 39:215-225

N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation

Authors: Granchi, Carlotta, Roy, Sarabindu, De Simone, Alessio, Salvetti, Irene, Tuccinardi, Tiziano, Martinelli, Adriano, Macchia, Marco, Lanza, Mario, Betti, Laura, Giannaccini, Gino, Lucacchini, Antonio, Giovannetti, Elisa, Sciarrillo, Rocco, Peters, Godefridus J., Minutolo, Filippo

Source: In European Journal of Medicinal Chemistry November 2011 46(11):5398-5407

Synergistic Activity of the c-Met and Tubulin Inhibitor Tivantinib (ARQ197) with Pemetrexed in Mesothelioma Cells

Authors: Leon, Leticia G., Gemelli, Maria, Sciarrillo, Rocco, Avan, Amir, Funel, Niccola, Giovannetti, Elisa

Source: Current drug targets. 15(14):1331-1340

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099987643.0x000001&indx=1&recIds=ETOCvdc_100099987643.0x000001

Author Correction: SF3B1 as therapeutic target in FLT3/ITD positive acute myeloid leukemia

Authors: van der Werf, Inge, Wojtuszkiewicz, Anna, Yao, Huilan, Sciarrillo, Rocco, Meggendorfer, Manja, Hutter, Stephan, Walter, Wencke, Janssen, Jeroen, Kern, Wolfgang, Haferlach, Claudia, Haferlach, Torsten, Jansen, Gerrit, Kaspers, Gertjan J. L., Groen, Richard, Ossenkoppele, Gert, Cloos, Jacqueline

Source: Leukemia. 35(9):2735-2735

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193028065.0x000001&indx=1&recIds=ETOCvdc_100193028065.0x000001

Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds.

Authors: Li Petri, Giovanna, El Hassouni, Btissame, Sciarrillo, Rocco, Funel, Niccola, Mantini, Giulia, Zeeuw van der Laan, Eveline A., Cascioferro, Stella, Avan, Amir, Zucali, Paolo Andrea, Zaffaroni, Nadia, Lagerweij, Tonny, Parrino, Barbara, Smid, Kees, Deraco, Marcello, Granchi, Carlotta, Braczko, Alicja, Smolenski, Ryszard T., Matherly, Larry H., Jansen, Gerrit, Assaraf, Yehuda G.

Source: British Journal of Cancer; Aug2020, Vol. 123 Issue 4, p644-656, 13p

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Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation.

Authors: Sciarrillo, Rocco¹ (AUTHOR), Wojtuszkiewicz, Anna² (AUTHOR) a.wojtuszkiewicz@amsterdamumc.nl, Kooi, Irsan E.³ (AUTHOR), Leon, Leticia G.⁴ (AUTHOR), Sonneveld, Edwin⁵ (AUTHOR), Kuiper, Roland P.⁵ (AUTHOR), Jansen, Gerrit⁶ (AUTHOR), Giovannetti, Elisa^7,8 (AUTHOR), Kaspers, Gertjan J.L.^5,9 (AUTHOR), Cloos, Jacqueline¹⁰ (AUTHOR)

Source: Cancers. Mar2020, Vol. 12 Issue 3, p723. 1p.

Subject Terms: *APOPTOSIS, *CELL cycle, *CELL lines, *CELLULAR signal transduction, *DRUG resistance in cancer cells, *ENERGY metabolism, *LYMPHOBLASTIC leukemia, *RNA, *GENE expression profiling, *CHILDREN, THERAPEUTIC use of glucocorticoids

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Synergistic Activity of the c-Met and Tubulin Inhibitor Tivantinib (ARQ197) with Pemetrexed in Mesothelioma Cells

Authors: G. Leon, Leticia, Gemelli, Maria, Sciarrillo, Rocco, Avan, Amir, Funel, Niccola, Giovannetti, Elisa

Source: Current Drug Targets; December 2014, Vol. 15 Issue: 14 p1331-1340, 10p

Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.

Authors: Blijlevens, Maxime, Komor, Malgorzata A., Sciarrillo, Rocco, Smit, Egbert F., Fijneman, Remond J. A., van Beusechem, Victor W.

Source: International Journal of Molecular Sciences; Jun2020, Vol. 21 Issue 12, p4192, 1p

Subject Terms: NON-small-cell lung carcinoma, RNA splicing, PROTEASOMES, SPLICEOSOMES, GENE expression, CANCER cells, MESSENGER RNA, NUCLEOTIDE sequence