Single-Cell mRNA-Seq of In Vitro-Derived Human Neurons Using Smart-Seq2

Authors: Schweingruber, Christoph, Nijssen, Jik, Benitez, Julio Aguila, Hedlund, Eva

Source: Methods in molecular biology. 2594:143-164

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630552690&indx=1&recIds=ETOCRN630552690

Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity

Authors: Correia, Jorge C., Kelahmetoglu, Yildiz, Jannig, Paulo R., Schweingruber, Christoph, Shvaikovskaya, Dasha, Zhengye, Liu, Cervenka, Igor, Khan, Naveen, Stec, Michael, Oliveira, Mariana, Nijssen, Jik, Martínez-Redondo, Vicente, Ducommun, Serge, Azzolini, Michele, Lanner, Johanna T., Kleiner, Sandra, Hedlund, Eva, Ruas, Jorge L.

Source: In Cell Metabolism 2 November 2021 33(11):2215-2230

Modeling Motor Neuron Resilience in ALS Using Stem Cells

Authors: Allodi, Ilary, Nijssen, Jik, Benitez, Julio Aguila, Schweingruber, Christoph, Fuchs, Andrea, Bonvicini, Gillian, Cao, Ming, Kiehn, Ole, Hedlund, Eva

Source: In Stem Cell Reports 11 June 2019 12(6):1329-1341

LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy

Authors: Nichterwitz, Susanne, Nijssen, Jik, Storvall, Helena, Schweingruber, Christoph, Comley, Laura Helen, Allodi, Ilary, van der Lee, Mirjam, Deng, Qiaolin, Sandberg, Rickard, Hedlund, Eva

Source: Genome research. 30(8):1083-1096

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624826757&indx=1&recIds=ETOCRN624826757

A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate

Authors: Newton, Phillip, Li, Lei, Zhou, Baoyi, Schweingruber, Christoph, Hovorakova, Maria, Xie, Meng, Sun, Xiaoyan, Sandhow, Lakshmi, Artemov, Artem, Ivashkin, Evgeny, Suter, Simon, Dyachuk, Vyacheslav, El Shahawy, Maha, Gritli-Linde, Amel, Bouderlique, Thibault, Petersen, Julian, Mollbrink, Annelie, Lundeberg, Joakim, Enikolopov, Grigori, Qian, Hong, Fried, Kaj, Kasper, Maria, Hedlund, Eva, Adameyko, Igor, Sävendahl, Lars, Chagin, Andrei

Source: Nature. 567(7747):234-238

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127967209.0x000001&indx=1&recIds=ETOCvdc_100127967209.0x000001

Challenges of profiling motor neuron transcriptomes from human spinal cord

Authors: Gautier, Olivia, Blum, Jacob A., Maksymetz, James, Chen, Derek, Schweingruber, Christoph, Mei, Irene, Hermann, Anita, Hackos, David H., Hedlund, Eva, Ravits, John, Gitler, Aaron D.

Source: In Neuron 6 December 2023 111(23):3739-3741

Nonsense-mediated mRNA decay — Mechanisms of substrate mRNA recognition and degradation in mammalian cells

Authors: Schweingruber, Christoph, Rufener, Simone C., Zünd, David, Yamashita, Akio, Mühlemann, Oliver

Source: In BBA - Gene Regulatory Mechanisms June-July 2013 1829(6-7):612-623

The Host Nonsense-Mediated mRNA Decay Pathway Restricts Mammalian RNA Virus Replication

Authors: Balistreri, Giuseppe, Horvath, Peter, Schweingruber, Christoph, Zünd, David, McInerney, Gerald, Merits, Andres, Mühlemann, Oliver, Azzalin, Claus, Helenius, Ari

Source: Cell host & microbe. 16(1):403-411

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100059104480.0x000001&indx=1&recIds=ETOCvdc_100059104480.0x000001

The Cell Autonomous and Non-Cell Autonomous Aspects of Neuronal Vulnerability and Resilience in Amyotrophic Lateral Sclerosis.

Authors: Schweingruber, Christoph¹ (AUTHOR), Hedlund, Eva¹ (AUTHOR) eva.hedlund@dbb.su.se

Source: Biology (2079-7737). Aug2022, Vol. 11 Issue 8, pN.PAG-N.PAG. 34p.

Subject Terms: *MOTOR neuron diseases, *AMYOTROPHIC lateral sclerosis, *EFFERENT pathways, *MOTOR neurons, *SPINAL cord, *SPHINCTERS, *BRAIN stem

Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID).

Authors: Schweingruber, Christoph^1,2, Soffientini, Paolo³, Ruepp, Marc-David¹, Bachi, Angela³, Mühlemann, Oliver¹ oliver.muehlemann@dcb.unibe.ch

Source: PLoS ONE. 3/2/2016, Vol. 11 Issue 3, p1-27. 27p.

Subject Terms: *ESCHERICHIA coli, *MESSENGER RNA, *BIOTIN, *LIGASES, *GENE expression

Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.

Authors: Jutzi, Daniel, Campagne, Sébastien, Schmidt, Ralf, Reber, Stefan, Mechtersheimer, Jonas, Gypas, Foivos, Schweingruber, Christoph, Colombo, Martino, von Schroetter, Christine, Loughlin, Fionna E., Devoy, Anny, Hedlund, Eva, Zavolan, Mihaela, Allain, Frédéric H.-T., Ruepp, Marc-David

Source: Nature Communications; 12/11/2020, Vol. 11 Issue 1, p1-14, 14p

Subject Terms: AMYOTROPHIC lateral sclerosis, MOTOR neuron diseases, SMALL nuclear RNA, RNA-binding proteins, SPINAL muscular atrophy, MOTOR neurons

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