Selecting the Optimal Parameters for Sonoporation of Pancreatic Cancer in a Pre-Clinical Model

Authors: Schultz, Christopher W., Liu, Ji-Bin, Dhir, Teena, Wessner, Corinne E., Zhang, Bo, Huang, Chunwang, Luo, Xianghong, Zhen, Yanhua, Niu, Sihua, Torkzaban, Mehnoosh, Wallace, Kirk, Eisenbrey, John R., Kotopoulis, Spiros, Brody, Jonathan, Forsberg, Flemming

Source: 2019 IEEE International Ultrasonics Symposium (IUS) Ultrasonics Symposium (IUS), 2019 IEEE International. :328-331 Oct, 2019

Relation: 2019 IEEE International Ultrasonics Symposium (IUS)

A Novel 3DNA® Nanocarrier effectively delivers payloads to pancreatic tumors

Authors: McCarthy, Grace A., Jain, Aditi, Di Niro, Roberto, Schultz, Christopher W., Jiang, Wei, Yeo, Charles J, Bowers, Jessica, Finan, Jennifer, Rhodes, Kelly, Casta, Lou, Hou, Vivi, Stefanoni, Anthony, Brown, Samantha Z., Nevler, Avinoam, Agostini, Lebaron C., Getts, Lori, Getts, Robert, Brody, Jonathan R.

Source: In Translational Oncology June 2023 32

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Authors: Thomas, Anish, Takahashi, Nobuyuki, Rajapakse, Vinodh N., Zhang, Xiaohu, Sun, Yilun, Ceribelli, Michele, Wilson, Kelli M., Zhang, Yang, Beck, Erin, Sciuto, Linda, Nichols, Samantha, Elenbaas, Brian, Puc, Janusz, Dahmen, Heike, Zimmermann, Astrid, Varonin, Jillian, Schultz, Christopher W., Kim, Sehyun, Shimellis, Hirity, Desai, Parth, Klumpp-Thomas, Carleen, Chen, Lu, Travers, Jameson, McKnight, Crystal, Michael, Sam, Itkin, Zina, Lee, Sunmin, Yuno, Akira, Lee, Min-Jung, Redon, Christophe E., Kindrick, Jessica D., Peer, Cody J., Wei, Jun S., Aladjem, Mirit I., Figg, William Douglas, Steinberg, Seth M., Trepel, Jane B., Zenke, Frank T., Pommier, Yves, Khan, Javed, Thomas, Craig J.

Source: In Cancer Cell 12 April 2021 39(4):566-579

Genomic alterations and transcriptional phenotypes in circulating free DNA and matched metastatic tumor.

Authors: Takahashi, Nobuyuki, Pongor, Lorinc, Agrawal, Shivam P., Shtumpf, Mariya, Gurjar, Ankita, Rajapakse, Vinodh N., Shafiei, Ahmad, Schultz, Christopher W., Kim, Sehyun, Roame, Diana, Carter, Paula, Vilimas, Rasa, Nichols, Samantha, Desai, Parth, Figg Sr., William Douglas, Bagheri, Mohammad, Teif, Vladimir B., Thomas, Anish

Source: Genome Medicine; 2/25/2025, Vol. 17 Issue 1, p1-16, 16p

Subject Terms: CELL-free DNA, SMALL cell lung cancer, TRANSCRIPTION factors, WHOLE genome sequencing, MEDICAL sciences, CIRCULATING tumor DNA

Effect of Hypercapnia, an Element of Obstructive Respiratory Disorder, on Pancreatic Cancer Chemoresistance and Progression

Authors: Nevler, Avinoam, Brown, Samantha Z., Nauheim, David, Portocarrero, Carla, Rodeck, Ulrich, Bassig, Jonathan, Schultz, Christopher W., McCarthy, Grace A., Lavu, Harish, Yeo, Theresa P., Yeo, Charles J., Brody, Jonathan R.

Source: In Journal of the American College of Surgeons April 2020 230(4):659-667

Distribution, Abundance, and Nest-site Characteristics of Black Swifts in the Southern Rocky Mountains of Colorado and New Mexico.

Authors: Levad, Richard G., Potter, Kim M., Schultz, Christopher W.

Source: Wilson Journal of Ornithology; June 2008, Vol. 120 Issue 2, p331-338, 8p

Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer: A Randomized Clinical Trial

Authors: Takahashi, Nobuyuki, Hao, Zhonglin, Villaruz, Liza C., Zhang, Jun, Ruiz, Jimmy, Petty, W. Jeffrey, Mamdani, Hirva, Riess, Jonathan W., Nieva, Jorge, Pachecho, Jose M., Fuld, Alexander D., Shum, Elaine, Chauhan, Aman, Nichols, Samantha, Shimellis, Hirity, McGlone, Jessie, Sciuto, Linda, Pinkiert, Danielle, Graham, Chante, Shelat, Meenakshi, Kattappuram, Robbie, Abel, Melissa, Schroeder, Brett, Upadhyay, Deep, Krishnamurthy, Manan, Sharma, Ajit Kumar, Kumar, Rajesh, Malin, Justin, Schultz, Christopher W., Goyal, Shubhank, Redon, Christophe E., Pommier, Yves, Aladjem, Mirit I., Gore, Steven D., Steinberg, Seth M., Vilimas, Rasa, Desai, Parth, Thomas, Anish

Source: JAMA Oncology; December 2023, Vol. 9 Issue: 12 p1669-1677, 9p

ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer.

Authors: Schultz, Christopher W, Zhang, Yang, Elmeskini, Rajaa, Zimmermann, Astrid, Fu, Haiqing, Murai, Yasuhisa, Wangsa, Darawalee, Kumar, Suresh, Takahashi, Nobuyuki, Atkinson, Devon, Saha, Liton Kumar, Lee, Chien‐Fei, Elenbaas, Brian, Desai, Parth, Sebastian, Robin, Sharma, Ajit Kumar, Abel, Melissa, Schroeder, Brett, Krishnamurthy, Manan, Kumar, Rajesh

Source: EMBO Molecular Medicine; 8/7/2023, Vol. 15 Issue 8, p1-17, 17p

Pyrvinium Pamoate: Past, Present, and Future as an Anti-Cancer Drug.

Authors: Schultz, Christopher W., Nevler, Avinoam

Source: Biomedicines; Dec2022, Vol. 10 Issue 12, p3249, 16p

Subject Terms: CANCER stem cells, ANTINEOPLASTIC agents, CYANINES, CELL proliferation

The RNA-Binding Protein HuR Posttranscriptionally Regulates the Protumorigenic Activator YAP1 in Pancreatic Ductal Adenocarcinoma.

Authors: Brown, Samantha Z., McCarthy, Grace A., Carroll, James R., Di Niro, Roberto, Pelz, Carl, Jain, Aditi, Sutton, Thomas L., Holly, Hannah D., Nevler, Avinoam, Schultz, Christopher W., McCoy, Matthew D., Cozzitorto Jr., Joseph A., Wei Jiang, Yeo, Charles J., Dixon, Dan A., Sears, Rosalie C., Brody, Jonathan R.

Source: Molecular & Cellular Biology; Jul2022, Vol. 42 Issue 7, p1-19, 19p

Subject Terms: RNA-binding proteins, YAP signaling proteins, PANCREATIC duct, RNA sequencing, SMALL interfering RNA, NUCLEOPROTEINS

Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models.

Authors: Lissa, Delphine, Takahashi, Nobuyuki, Desai, Parth, Manukyan, Irena, Schultz, Christopher W., Rajapakse, Vinodh, Velez, Moises J., Mulford, Deborah, Roper, Nitin, Nichols, Samantha, Vilimas, Rasa, Sciuto, Linda, Chen, Yuanbin, Guha, Udayan, Rajan, Arun, Atkinson, Devon, El Meskini, Rajaa, Weaver Ohler, Zoe, Thomas, Anish

Source: Nature Communications; 4/19/2022, Vol. 13 Issue 1, p1-16, 16p

Subject Terms: SMALL cell lung cancer, NOTCH genes

Splenic-vasculature involvement is associated with poor prognosis in resected distal pancreatic cancer.

Authors: Yin, Feng, Saad, Mohammed, Lin, Jingmei, Jackson, Christopher R, Ren, Bing, Lawson, Cynthia, Karamchandani, Dipti M, Bernabeu, Belen Quereda, Jiang, Wei, Dhir, Teena, Zheng, Richard, Schultz, Christopher W, Zhang, Dongwei, Thomas, Courtney L, Zhang, Xuchen, Lai, Jinping, Schild, Michael, Zhang, Xuefeng, Xie, Hao, Liu, Xiuli

Source: Gastroenterology Report; Apr2021, Vol. 9 Issue 2, p139-145, 7p

Subject Terms: PANCREATIC cancer, PROGRESSION-free survival, SPLENIC vein

Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model.

Authors: Schultz, Christopher W.¹ (AUTHOR), Ruiz de Garibay, Gorka² (AUTHOR), Langer, Anika² (AUTHOR), Liu, Ji-Bin¹ (AUTHOR), Dhir, Teena¹ (AUTHOR), Leitch, Calum² (AUTHOR), Wessner, Corinne E.¹ (AUTHOR), Mayoral, Mireia² (AUTHOR), Zhang, Bo³ (AUTHOR), Popa, Mihaela² (AUTHOR), Huang, Chunwang⁴ (AUTHOR), Kotopoulis, Spiros^2,5 (AUTHOR), Luo, Xianghong⁶ (AUTHOR), Zhen, Yanhua⁷ (AUTHOR), Niu, Sihua⁸ (AUTHOR), Torkzaban, Mehnoosh¹ (AUTHOR), Wallace, Kirk⁹ (AUTHOR), Eisenbrey, John R.¹ (AUTHOR), Brody, Jonathan R.¹ (AUTHOR), McCormack, Emmet² (AUTHOR)

Source: Cancer Biology & Therapy. 2021, Vol. 22 Issue 3, p204-215. 12p.

Subject Terms: *ULTRASOUND contrast media, *PANCREATIC cancer, *ANIMAL models in research, *ULTRASONIC imaging

Margin-Positive Pancreatic Ductal Adenocarcinoma during Pancreaticoduodenectomy: Additional Resection Does Not Improve Survival.

Authors: Zheng, Richard, Nauheim, David, Bassig, Jonathan, Chadwick, Matthew, Schultz, Christopher W., Krampitz, Geoffrey, Lavu, Harish, Winter, Jordan R., Yeo, Charles J., Berger, Adam C.

Source: Annals of Surgical Oncology: An Oncology Journal for Surgeons; Mar2021, Vol. 28 Issue 3, p1552-1562, 11p

Understanding and targeting the disease‐related RNA binding protein human antigen R (HuR).

Authors: Schultz, Christopher W., Preet, Ranjan, Dhir, Teena, Dixon, Dan A., Brody, Jonathan R.

Source: Wiley Interdisciplinary Reviews: RNA; May/Jun2020, Vol. 11 Issue 3, p1-21, 21p

ASO Author Reflections: Margin-Positive Pancreatic Ductal Adenocarcinoma During Pancreaticoduodenectomy: Additional Resection Does Not Improve Survival.

Authors: Zheng, Richard, Nauheim, David, Bassig, Jonathan, Chadwick, Matthew, Schultz, Christopher W., Krampitz, Geoffrey, Lavu, Harish, Winter, Jordan R., Yeo, Charles J., Berger, Adam C.

Source: Annals of Surgical Oncology: An Oncology Journal for Surgeons; Jun2020 Supplement 3, Vol. 27 Issue 3, p895-896, 2p

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