ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

Authors: Nalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele W.L., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra, MacDonald, Kelli P.A.

Source: In JHEP Reports January 2022 4(1)

Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner

Authors: Willis, Emily F., MacDonald, Kelli P.A., Nguyen, Quan H., Garrido, Adahir Labrador, Gillespie, Ellen R., Harley, Samuel B.R., Bartlett, Perry F., Schroder, Wayne A., Yates, Abi G., Anthony, Daniel C., Rose-John, Stefan, Ruitenberg, Marc J., Vukovic, Jana

Source: In Cell 5 March 2020 180(5):833-846

Cheminformatics-Guided Exploration of Synthetic Marine Natural Product-Inspired Brominated Indole-3-Glyoxylamides and Their Potentials for Drug Discovery.

Authors: Holland, Darren C., Prebble, Dale W., Calcott, Mark J., Schroder, Wayne A., Ferretti, Francesca, Lock, Aaron, Avery, Vicky M., Kiefel, Milton J., Carroll, Anthony R.

Source: Molecules; Aug2024, Vol. 29 Issue 15, p3648, 24p

Subject Terms: MARINE natural products, DRUG discovery, INDOLE alkaloids, PARKINSON'S disease, BIOLOGICAL assay

SerpinB2 deficiency in mice reduces bleeding times via dysregulated platelet activation

Authors: Schroder, Wayne A, Le, Thuy T, Gardner, Joy, Andrews, Robert K., Gardiner, Elizabeth E., Callaway, Leonie, Suhrbier, Andreas

Source: Platelets. 30(5):658-663

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105855139.0x000001&indx=1&recIds=ETOCvdc_100105855139.0x000001

SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages

Authors: Schroder, Wayne [and others]

Source: Scientific reports. 9(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190519450.0x000001&indx=1&recIds=ETOCvdc_100190519450.0x000001

SerpinB2 Deficiency Results in a Stratum Corneum Defect and Increased Sensitivity to Topically Applied Inflammatory Agents

Authors: Schroder, Wayne A., Anraku, Itaru, Le, Thuy T., Hirata, Thiago D.C., Nakaya, Helder I., Major, Lee, Ellis, Jonathan J., Suhrbier, Andreas

Source: In The American Journal of Pathology June 2016 186(6):1511-1523

Effective cutaneous vaccination using an inactivated chikungunya virus vaccine delivered by Foroderm

Authors: Rudd, Penny A., Raphael, Anthony P., Yamada, Miko, Nufer, Kaitlin L., Gardner, Joy, Le, Thuy T.T., Prow, Natalie A., Dang, Nhung, Schroder, Wayne A., Prow, Tarl W., Suhrbier, Andreas

Source: In Vaccine 22 September 2015 33(39):5172-5180

Cyclotheonellazoles D‑I, Potent Elastase Inhibitory Thiazole-Containing Cyclic Peptides from Theonella sp. (2131).

Authors: Holland, Darren C., Schroder, Wayne A., Calcott, Mark J., Kaemmerer, Elke, Avery, Vicky M., Ekins, Merrick G., Carroll, Anthony R.

Source: Journal of Natural Products; 9/22/2023, Vol. 86 Issue 9, p2216-2227, 12p

Disseminated Varicella Infection Caused by Varicella Vaccine Strain in a Child With Low Invariant Natural Killer T Cells and Diminished CD1d Expression

Authors: Banovic, Tatjana, Yanilla, Mayonelo, Simmons, Russell, Robertson, Ian, Schroder, Wayne A., Raffelt, Neil C., Wilson, Yana A., Hill, Geoffrey R., Hogan, Patrick, Nourse, Clare B.

Source: The Journal of Infectious Diseases, 2011 Dec 01. 204(12), 1893-1901.

Access URL: http://dx.doi.org/10.1093/infdis/jir660

Dual Stimulation of MyD88-Dependent Toll-Like Receptors Induces Synergistically Enhanced Production of Inflammatory Cytokines in Murine Bone Marrow–Derived Dendritic Cells

Authors: Mitchell, Daniel, Yong, Michelle, Schroder, Wayne, Black, Matthew, Tirrell, Matthew, Olive, Colleen

Source: The Journal of Infectious Diseases, 2010 Jul . 202(2), 318-329.

Access URL: https://www.jstor.org/stable/27822453

Human papilloma virus transformed CaSki cells constitutively express high levels of functional SerpinB2

Authors: Major, Lee, Schroder, Wayne A., Gardner, Joy, Fish, Richard J., Suhrbier, Andreas

Source: In Experimental Cell Research 1 February 2011 317(3):338-347

Dual Loss of Rb1 and Trp53 in the Adrenal Medulla Leads to Spontaneous Pheochromocytoma

Authors: Tonks, Ian D., Mould, Arne W., Schroder, Wayne A., Cotterill, Andrew, Hayward, Nicholas K., Walker, Graeme J., Kay, Graham F.

Source: In Neoplasia March 2010 12(3):235-243

Cyclotheonellazoles D-I, Potent Elastase Inhibitory Thiazole-Containing Cyclic Peptides from Theonellasp. (2131)

Authors: Holland, Darren C., Schroder, Wayne A., Calcott, Mark J., Kaemmerer, Elke, Avery, Vicky M., Ekins, Merrick G., Carroll, Anthony R.

Source: Journal of Natural Products; September 2023, Vol. 86 Issue: 9 p2216-2227, 12p

Immunostimulatory cancer chemotherapy using local ingenol-3-angelate and synergy with immunotherapies

Authors: Le, Thuy T.T., Gardner, Joy, Hoang-Le, Diem, Schmidt, Chris W., MacDonald, Kelli P., Lambley, Eleanore, Schroder, Wayne A., Ogbourne, Steven M., Suhrbier, Andreas

Source: In Vaccine 2009 27(23):3053-3062

Kunjin replicon-based simian immunodeficiency virus gag vaccines

Authors: Anraku, Itaru, Mokhonov, Vladislav V., Rattanasena, Paweena, Mokhonova, Ekaterina I., Leung, Jason, Pijlman, Gorben, Cara, Andrea, Schroder, Wayne A., Khromykh, Alexander A., Suhrbier, Andreas

Source: In Vaccine 2008 26(26):3268-3276

Human Papillomavirus E7 Requires the Protease Calpain to Degrade the Retinoblastoma Protein

Authors: Darnell, Grant A., Schroder, Wayne A., Antalis, Toni M., Lambley, Eleanore, Major, Lee, Gardner, Joy, Birrell, Geoff, Cid-Arregui, Angel, Suhrbier, Andreas

Source: In Journal of Biological Chemistry 28 December 2007 282(52):37492-37500

Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling

Authors: Schroder, Wayne A., Buck, Marion, Cloonan, Nicole, Hancock, John F., Suhrbier, Andreas, Sculley, Tom, Bushell, Gillian

Source: In Cellular Signalling June 2007 19(6):1279-1289

SerpinB2 Is an Inducible Host Factor Involved in Enhancing HIV-1 Transcription and Replication

Authors: Darnell, Grant A., Schroder, Wayne A., Gardner, Joy, Harrich, David, Yu, Hong, Medcalf, Robert L., Warrilow, David, Antalis, Toni M., Sonza, Secondo, Suhrbier, Andreas

Source: In Journal of Biological Chemistry 20 October 2006 281(42):31348-31358

The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins

Authors: Schroder, Wayne ^*, Bushell, Gillian, Sculley, Tom

Source: In Cellular Signalling 2005 17(6):761-767

Lower temperatures reduce type I interferon activity and promote alphaviral arthritis.

Authors: Prow, Natalie A.^1,2, Tang, Bing¹, Gardner, Joy¹, Le, Thuy T.¹, Taylor, Adam³, Poo, Yee S.¹, Nakayama, Eri^1,4, Hirata, Thiago D. C.^1,5, Nakaya, Helder I.⁵, Slonchak, Andrii⁶, Mukhopadhyay, Pamela¹, Mahalingam, Suresh³, Schroder, Wayne A.¹, Klimstra, William⁷, Suhrbier, Andreas^1,2, Andreas.Suhrbier@qimrberghofer.edu.au

Source: PLoS Pathogens; 12/27/2017, Vol. 13 Issue 12, p1-25, 25p