De novo design of high-affinity protein binders with AlphaProteo

Authors: Zambaldi, Vinicius, La, David, Chu, Alexander E., Patani, Harshnira, Danson, Amy E., Kwan, Tristan O. C., Frerix, Thomas, Schneider, Rosalia G., Saxton, David, Thillaisundaram, Ashok, Wu, Zachary, Moraes, Isabel, Lange, Oskar, Papa, Eliseo, Stanton, Gabriella, Martin, Victor, Singh, Sukhdeep, Wong, Lai H., Bates, Russ, Kohl, Simon A., Abramson, Josh, Senior, Andrew W., Alguel, Yilmaz, Wu, Mary Y., Aspalter, Irene M., Bentley, Katie, Bauer, David L. V., Cherepanov, Peter, Hassabis, Demis, Kohli, Pushmeet, Fergus, Rob, Wang, Jue

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/2409.08022

Laser: Latent Set Representations for 3D Generative Modeling

Authors: Moreno, Pol, Kosiorek, Adam R., Strathmann, Heiko, Zoran, Daniel, Schneider, Rosalia G., Winckler, Björn, Markeeva, Larisa, Weber, Théophane, Rezende, Danilo J.

Subject Terms: Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence

Access URL: http://arxiv.org/abs/2301.05747

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Accurate proteome-wide missense variant effect prediction with AlphaMissense.

Authors: Jun Cheng, Novati, Guido, Pan, Joshua, Bycroft, Clare, Žemgulyte, Akvile, Applebaum, Taylor, Pritzel, Alexander, Lai Hong Wong, Zielinski, Michal, Sargeant, Tobias, Schneider, Rosalia G., Senior, Andrew W., Jumper, John, jucheng@google.com, Hassabis, Demis, Kohli, Pushmeet, pushmeet@google.com, Avsec, Žiga, avsec@google.com

Source: Science; 9/22/2023, Vol. 381 Issue 6664, p1303-1303, 1p, 1 Diagram

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