Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity

Authors: Lokumcu, Tolga, Iskar, Murat, Schneider, Martin, Helm, Dominic, Klinke, Glynis, Schlicker, Lisa, Bethke, Frederic, Müller, Gabriele, Richter, Karsten, Poschet, Gernot

Source: ACS NANO. 18(3):2500-2519

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632773684&indx=1&recIds=ETOCRN632773684

Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function

Authors: Kurniawan, Henry, Franchina, Davide G., Guerra, Luana, Bonetti, Lynn, - Baguet, Leticia Soriano, Grusdat, Melanie, Schlicker, Lisa, Hunewald, Oliver, Dostert, Catherine, Merz, Myriam P., Binsfeld, Carole, Duncan, Gordon S., Farinelle, Sophie, Nonnenmacher, Yannic, Haight, Jillian, Das Gupta, Dennis, Ewen, Anouk, Taskesen, Rabia, Halder, Rashi, Chen, Ying, Jäger, Christian, Ollert, Markus, Wilmes, Paul, Vasiliou, Vasilis, Harris, Isaac S., Knobbe-Thomsen, Christiane B., Turner, Jonathan D., Mak, Tak W., Lohoff, Michael, Meiser, Johannes, Hiller, Karsten, Brenner, Dirk

Source: In Cell Metabolism 5 May 2020 31(5):920-936

LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

Authors: Alborzinia, Hamed, Chen, Zhiyi, Yildiz, Umut, Freitas, Florencio Porto, Vogel, Felix C E, Varga, Julianna Patricia, Batani, Jasmin, Bartenhagen, Christoph, Schmitz, Werner, Büchel, Gabriele, Michalke, Bernhard, Zheng, Jashuo, Meierjohann, Svenja, Girardi, Enrico, Espinet, Elisa, Flórez, Andrés F, Santos, Ancely Ferreira, Aroua, Nesrine, Cheytan, Tasneem, Haenlin, Julie, Schlicker, Lisa, Xavier da Silva, Thamara N, Przybylla, Adriana, Zeisberger, Petra, Superti‐Furga, Giulio, Eilers, Martin, Conrad, Marcus, Fabiano, Marietta, Schweizer, Ulrich, Fischer, Matthias, Schulze, Almut, Trumpp, Andreas, Friedmann Angeli, José Pedro

Source: EMBO molecular medicine. 15(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189952299.0x000001&indx=1&recIds=ETOCvdc_100189952299.0x000001

Unexpected roles for ADH1 and SORD in catalyzing the final step of erythritol biosynthesis

Alternate Title: ADH1 and SORD catalyze erythritol synthesis (English)

Authors: Schlicker, Lisa, Szebenyi, Doletha M.E., Ortiz, Semira R., Heinz, Alexander, Hiller, Karsten, Field, Martha S.

Source: In Journal of Biological Chemistry 1 November 2019 294(44):16095-16108

Non-Targeted Mass Isotopolome Analysis Using Stable Isotope Patterns to Identify Metabolic Changes

Authors: Dudek, Christian-Alexander, Schlicker, Lisa, Hiller, Karsten

Source: Methods in molecular biology. 2088:17-32

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622550347&indx=1&recIds=ETOCRN622550347

A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs.

Authors: Wang, Changwen, Sun, Meng, Shao, Chunxuan, Schlicker, Lisa, Zhuo, Yue, Harim, Yassin, Peng, Tianping, Tian, Weili, Stöffler, Nadja, Schneider, Martin, Helm, Dominic, Chu, Youjun, Fu, Beibei, Jin, Xiaoliang, Mallm, Jan-Philipp, Mall, Moritz, Wu, Yonghe, Schulze, Almut, Liu, Hai-Kun

Source: NPJ Precision Oncology; 1/26/2024, Vol. 8 Issue 1, p1-21, 21p

Subject Terms: GLIOBLASTOMA multiforme, ORGANOIDS

p53 deficient breast cancer cells reprogram preadipocytes toward tumor-protective immunomodulatory cells.

Authors: Hassin, Ori, Sernik, Miriam, Seligman, Adi, Vogel, Felix C. E., Wellenstein, Max D., Smollich, Joachim, Halperin, Coral, Pirona, Anna Chiara, Toledano, Liron Nomi, Caballero, Carolina Dehesa, Schlicker, Lisa, Salame, Tomer-Meir, Portuguez, Avital Sarusi, Aylon, Yael, Scherz-Shouval, Ruth, Geiger, Tamar, de Visser, Karin E., Schulze, Almut, Oren, Moshe

Source: Proceedings of the National Academy of Sciences of the United States of America; 12/26/2023, Vol. 120 Issue 52, p1-12, 99p

Subject Terms: BREAST cancer, CANCER cells, MYELOID cells, IMMUNE checkpoint proteins, ADIPOSE tissues, REMANUFACTURING

CaMKII regulates cardiac metabolic substrate switching during heart failure

Authors: Saadatmand, Alireza, Pepin, Mark, Haberkorn, Uwe, Okun, Jürgen, Schlicker, Lisa, Schulze, Almut, Backs, Johannes

Source: Journal of molecular and cellular cardiology. 173(S):S189-S189

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194317795.0x000001&indx=1&recIds=ETOCvdc_100194317795.0x000001

USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer

Authors: Maier, Carina R., Hartmann, Oliver, Prieto-Garcia, Cristian, Al-Shami, Kamal M., Schlicker, Lisa, Vogel, Felix C. E., Haid, Silke, Klann, Kevin, Buck, Viktoria, Münch, Christian, Schmitz, Werner, Einig, Elias, Krenz, Bastian, Calzado, Marco A., Eilers, Martin, Popov, Nikita, Rosenfeldt, Mathias T., Diefenbacher, Markus E., Schulze, Almut

Source: Cell Death and Differentiation; July 2023, Vol. 30 Issue: 7 p1710-1725, 16p

c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis.

Authors: Vollmuth, Nadine¹, Schlicker, Lisa², Yongxia Guo^1,3, Hovhannisyan, Pargev¹, Janaki-Raman, Sudha⁴, Kurmasheva, Naziia¹, Schmitz, Werner⁵, Schulze, Almut^2,5, Stelzner, Kathrin¹, Rajeeve, Karthika^1,6, Rudel, Thomas¹ thomas.rudel@uni-wuerzburg.de

Source: eLife. 9/26/2022, p1-26. 26p.

Subject Terms: *CHLAMYDIA trachomatis, *CELL metabolism, *TRICARBOXYLIC acids, *TRYPTOPHAN, *CELL lines, *FALLOPIAN tubes, *TRP channels

Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals

Authors: Barayeu, Uladzimir, Schilling, Danny, Eid, Mohammad, Xavier da Silva, Thamara Nishida, Schlicker, Lisa, Mitreska, Nikolina, Zapp, Christopher, Gräter, Frauke, Miller, Aubry K., Kappl, Reinhard, Schulze, Almut, Friedmann Angeli, José Pedro, Dick, Tobias P.

Source: Nature Chemical Biology; 20220101, Issue: Preprints p1-10, 10p

Plasma Metabolome Signature Indicative of BRCA1 Germline Status Independent of Cancer Incidence.

Authors: Penkert, Judith, Märtens, Andre, Seifert, Martin, Auber, Bernd, Derlin, Katja, Hille-Betz, Ursula, Hörmann, Philipp, Klopp, Norman, Prokein, Jana, Schlicker, Lisa, Wacker, Frank, Wallaschek, Hannah, Schlegelberger, Brigitte, Hiller, Karsten, Ripperger, Tim, Illig, Thomas

Source: Frontiers in Oncology; 4/7/2021, Vol. 11, pN.PAG-N.PAG, 10p

Subject Terms: BRCA genes, CANCER genes, GERM cells, CELLULAR evolution, ENERGY metabolism, HEREDITARY nonpolyposis colorectal cancer

Formate promotes invasion and metastasis in reliance on lipid metabolism.

Authors: Delbrouck, Catherine, Kiweler, Nicole, Chen, Oleg, Pozdeev, Vitaly I., Haase, Lara, Neises, Laura, Oudin, Anaïs, Fouquier d'Hérouël, Aymeric, Shen, Ruolin, Schlicker, Lisa, Halder, Rashi, Lesur, Antoine, Schuster, Anne, Lorenz, Nadja I., Jaeger, Christian, Feucherolles, Maureen, Frache, Gilles, Szpakowska, Martyna, Chevigne, Andy, Ronellenfitsch, Michael W.

Source: Cell Reports; Sep2023, Vol. 42 Issue 9, pN.PAG-N.PAG, 1p

Integrated Metabolomics and Transcriptomics Analysis of Monolayer and Neurospheres from Established Glioblastoma Cell Lines.

Authors: Peixoto, Joana, Janaki-Raman, Sudha, Schlicker, Lisa, Schmitz, Werner, Walz, Susanne, Winkelkotte, Alina M., Herold-Mende, Christel, Soares, Paula, Schulze, Almut, Lima, Jorge, Pollok, Karen E., Nagrath, Deepak

Source: Cancers; Mar2021, Vol. 13 Issue 6, p1327, 1p

Subject Terms: NEURON analysis, ARGININE metabolism, METABOLOMICS, GLIOMAS, METABOLISM, CELL physiology, GENE expression profiling, STEM cells, CELL proliferation, GENES, TRANSCRIPTION factors, CELL lines

Postprandial Metabolic Effects of Fiber Mixes Revealed by in vivo Stable Isotope Labeling in Humans.

Authors: Schlicker, Lisa, Boers, Hanny M., Dudek, Christian-Alexander, Zhao, Gang, Barua, Arnab, Trezzi, Jean-Pierre, Meyer-Hermann, Michael, Jacobs, Doris M., Hiller, Karsten

Source: Metabolites (2218-1989); May2019, Vol. 9 Issue 5, p91-91, 1p

Subject Terms: GUAR gum, RADIOLABELING, STABLE isotopes, TYPE 2 diabetes, FLOUR

Company/Entity: MICROSOFT Corp.