Non-ceruloplasmin copper and urinary copper in clinically stable Wilson disease: Alignment with recommended targets

Authors: Ott, Peter, Sandahl, Thomas, Ala, Aftab, Cassiman, David, Couchonnal-Bedoya, Eduardo, Cury, Rubens Gisbert, Czlonkowska, Anna, Denk, Gerald, D’Inca, Renata, de Assis Aquino Gondim, Francisco, Moore, Joanna, Poujois, Aurelia, Twardowschy, Carlos Alexandre, Weiss, Karl Heinz, Zuin, Massimo, Kamlin, C.Omar F., Schilsky, Michael L.

Source: In JHEP Reports August 2024 6(8)

Effects of tetrathiomolybdate on copper metabolism in healthy volunteers and in patients with Wilson disease

Authors: Kirk, Frederik Teicher, Munk, Ditte Emilie, Swenson, Eugene Scott, Quicquaro, Adam Michael, Vendelbo, Mikkel Holm, Larsen, Agnete, Schilsky, Michael L., Ott, Peter, Sandahl, Thomas Damgaard

Source: In Journal of Hepatology April 2024 80(4):586-595

A multidisciplinary approach to the diagnosis and management of Wilson disease: Executive summary of the 2022 Practice Guidance on Wilson disease from the American Association for the Study of Liver Diseases

Authors: Schilsky, Michael L., Roberts, Eve A., Bronstein, Jeff M., Dhawan, Anil, Hamilton, James P., Rivard, Anne Marie, Washington, Mary Kay, Weiss, Karl Heinz, Zimbrean, Paula C.

Source: Hepatology. 77(4):1428-1455

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187833713.0x000001&indx=1&recIds=ETOCvdc_100187833713.0x000001

Major Depressive Disorder in an International Multisite Wilson Disease Registry

Authors: Camarata, Michelle A., Ala, Aftab, Coskun, Ayse K., Deng, Yanhong, Embel, Veysel K., Gonzalez-Peralta, Regino, Maciejewski, Kaitlin R., Patel, Amar, Rubman, Susan, To, Uyen, Tomlin, Ricarda, Schilsky, Michael L., Zimbrean, Paula C.

Source: Journal of the Academy of Consultation. 64(2):106-117

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185817774.0x000001&indx=1&recIds=ETOCvdc_100185817774.0x000001

Trientine tetrahydrochloride versus penicillamine for maintenance therapy in Wilson disease (CHELATE): a randomised, open-label, non-inferiority, phase 3 trial

Authors: To, Uyen, Patel, Amar, Hettiarachchi, Daksshi, Giorgini, Alessia, Monico, Sara, Litwin, Tomasz, Piechal, Agnieszka, Skowronska, Marta, Lachaux, Alain, Belmalih, Abdelouahed, Boogers, Alexandra, Mohr, Isabelle, Langel, Andrea, Freitas, Christian, Barbosa, Egberto Reis, Sandahl, Thomas D, Gerdes, Lisbet, Obadia, Alexandre, Rahli, Djamila, Cosgrove, Jeremy, Schilsky, Michael L ^*, Czlonkowska, Anna, Zuin, Massimo, Cassiman, David, Twardowschy, Carlos, Poujois, Aurelia, Gondim, Francisco de Assis A, Denk, Gerald, Cury, Rubens G, Ott, Peter, Moore, Joanna, Ala, Aftab, D'Inca, Renata, Couchonnal-Bedoya, Eduardo, D'Hollander, Koenraad, Dubois, Nicolas, Kamlin, C Omar F, Weiss, Karl Heinz

Source: In The Lancet Gastroenterology & Hepatology December 2022 7(12):1092-1102

Trientine tetrahydrochloride versus penicillamine for maintenance therapy in Wilson disease (CHELATE): a randomised, open-label, non-inferiority, phase 3 trial

Authors: Schilsky, Michael L, Czlonkowska, Anna, Zuin, Massimo, Cassiman, David, Twardowschy, Carlos, Poujois, Aurelia, Gondim, Francisco de Assis A, Denk, Gerald, Cury, Rubens G, Ott, Peter, Moore, Joanna, Ala, Aftab, D'Inca, Renata, Couchonnal-Bedoya, Eduardo, D'Hollander, Koenraad, Dubois, Nicolas, Kamlin, C Omar F, Weiss, Karl Heinz

Source: Lancet.Gastroenterology & hepatology. 7(12):1092-1102

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183240859.0x000001&indx=1&recIds=ETOCvdc_100183240859.0x000001

Accurate non-ceruloplasmin bound copper: a new biomarker for the assessment and monitoring of Wilson disease patients using HPLC coupled to ICP-MS/MS.

Authors: Harrington, Chris F., Carpenter, Geoff, Coverdale, James P.C., Douglas, Leisa, Mills, Craig, Willis, Karl, Schilsky, Michael L.

Source: Clinical Chemistry & Laboratory Medicine; Jan2025, Vol. 63 Issue 2, p320-328, 9p

Subject Terms: COPPER, BLOOD proteins, GRADIENT elution (Chromatography), MEDICAL registries, CHEMICAL speciation

The Effect of Mental Health, Neurological Disease, and Liver Disease on Quality of Life in Patients With Wilson Disease

Authors: Camarata, Michelle A., Ala, Aftab, Coskun, Ayse K., Deng, Yanhong, Gonzalez-Peralta, Regino P., Maciejewski, Kaitlin R., Patel, Amar, Rubman, Susan, To, Uyen, Tomlin, Ricarda, Schilsky, Michael L., Zimbrean, Paula C.

Source: In Journal of the Academy of Consultation-Liaison Psychiatry September-October 2021 62(5):528-537

Direct Measurement of ATP7B Peptides Is Highly Effective in the Diagnosis of Wilson Disease

Authors: Collins, Christopher J., Yi, Fan, Dayuha, Remwilyn, Duong, Phi, Horslen, Simon, Camarata, Michelle, Coskun, Ayse K., Houwen, Roderick H.J., Pop, Tudor L., Zoller, Heinz, Yoo, Han-wook, Jung, Sung Won, Weiss, Karl H., Schilsky, Michael L., Ferenci, Peter, Hahn, Si Houn

Source: In Gastroenterology June 2021 160(7):2367-2382

Designing Clinical Trials in Wilson's Disease

Authors: Ott, Peter, Ala, Aftab, Askari, Frederick K., Czlonkowska, Anna, Hilgers, Ralf‐Dieter, Poujois, Aurélia, Roberts, Eve A., Sandahl, Thomas Damgaard, Weiss, Karl Heinz, Ferenci, Peter, Schilsky, Michael L.

Source: Hepatology. 74(6):3460-3471

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135784932.0x000001&indx=1&recIds=ETOCvdc_100135784932.0x000001

Coagulopathy, Bleeding Events, and Outcome According to Rotational Thromboelastometry in Patients With Acute Liver Injury/Failure

Authors: Stravitz, R. Todd, Fontana, Robert J., Meinzer, Caitlyn, Durkalski‐Mauldin, Valerie, Hanje, A. James, Olson, Jody, Koch, David, Hamid, Bilal, Schilsky, Michael L., McGuire, Brendan, Ganger, Daniel, Liou, Iris, Karvellas, Constantine J., Rule, Jody A., Lisman, Ton, Clasen, Kristin, Reuben, Adrian, Cripps, Michael, Lee, William M.

Source: Hepatology. 74(2):937-949

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135391624.0x000001&indx=1&recIds=ETOCvdc_100135391624.0x000001

American Association for the Study of Liver Diseases Expert Panel Consensus Statement: Vaccines to Prevent Coronavirus Disease 2019 Infection in Patients With Liver Disease

Authors: Fix, Oren K., Blumberg, Emily A., Chang, Kyong‐Mi, Chu, Jaime, Chung, Raymond T., Goacher, Elizabeth K., Hameed, Bilal, Kaul, Daniel R., Kulik, Laura M., Kwok, Ryan M., McGuire, Brendan M., Mulligan, David C., Price, Jennifer C., Reau, Nancy S., Reddy, K. Rajender, Reynolds, Andrew, Rosen, Hugo R., Russo, Mark W., Schilsky, Michael L., Verna, Elizabeth C., Ward, John W., Fontana, Robert J.

Source: Hepatology. 74(2):1049-1064

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135391593.0x000001&indx=1&recIds=ETOCvdc_100135391593.0x000001

Chapter 30 - Wilson disease

Authors: To, Uyen, Schilsky, Michael L.

Source: In Hepatology 2025:841-859

Transjugular intrahepatic portosystemic shunt as a bridge to liver transplant: Current state and future directions

Authors: Sellers, Cortlandt M., Nezami, Nariman, Schilsky, Michael L., Kim, Hyun S.

Source: In Transplantation Reviews April 2019 33(2):64-71

Management of Wilson Disease Diagnosed in Infancy: An Appraisal of Available Experience to Generate Discussion

Authors: Valentino, Pamela L., Roberts, Eve A., Beer, Stacey, Miloh, Tamir, Arnon, Ronen, Vittorio, Jennifer M., Schilsky, Michael L.

Source: Journal of pediatric gastroenterology and nutrition. 70(5):547-554

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181765910.0x000001&indx=1&recIds=ETOCvdc_100181765910.0x000001

Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID‐19 Pandemic: AASLD Expert Panel Consensus Statement

Authors: Fix, Oren K., Hameed, Bilal, Fontana, Robert J., Kwok, Ryan M., McGuire, Brendan M., Mulligan, David C., Pratt, Daniel S., Russo, Mark W., Schilsky, Michael L., Verna, Elizabeth C., Loomba, Rohit, Cohen, David E., Bezerra, Jorge A., Reddy, K. Rajender, Chung, Raymond T.

Source: Hepatology. 72(1):287-304

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107538439.0x000001&indx=1&recIds=ETOCvdc_100107538439.0x000001

Outcomes of Acute Liver Injury in Adults Due to Wilson's Disease: Is Survival Without Transplant Possible?

Authors: Camarata, Michelle A., Gottfried, Michelle, Rule, Jody A., Ala, Aftab, Lee, William M., Todd Stravitz, R., Schilsky, Michael L.

Source: Liver transplantation. 26(3):330-336

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103019252.0x000001&indx=1&recIds=ETOCvdc_100103019252.0x000001

Zinc Maintenance Therapy for Wilson Disease: A Comparison Between Zinc Acetate and Alternative Zinc Preparations

Authors: Camarata, Michelle A., Ala, Aftab, Schilsky, Michael L.

Source: Hepatology research. 3(8):1151-1158

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096902007.0x000001&indx=1&recIds=ETOCvdc_100096902007.0x000001

Bis-choline tetrathiomolybdate in patients with Wilson's disease: an open-label, multicentre, phase 2 study

Authors: Weiss, Karl Heinz, Askari, Frederick K, Czlonkowska, Anna, Ferenci, Peter, Bronstein, Jeff M, Bega, Danny, Ala, Aftab, Nicholl, David, Flint, Susan, Olsson, Lars, Plitz, Thomas, Bjartmar, Carl, Schilsky, Michael L

Source: In The Lancet Gastroenterology & Hepatology December 2017 2(12):869-876

Wilson Disease: Diagnosis, Treatment, and Follow-up

Authors: Schilsky, Michael L.

Source: In Clinics in Liver Disease November 2017 21(4):755-767