Fast, multicolour optical sectioning over extended fields of view by combining interferometric SIM with machine learning

Authors: Ward, Edward N., McClelland, Rebecca M., Lamb, Jacob R., Rubio-Sánchez, Roger, Christensen, Charles N., Mazumder, Bismoy, Kapsiani, Sofia, Mascheroni, Luca, Di Michele, Lorenzo, Schierle, Gabriele S. Kaminski, Kaminski, Clemens F.

Subject Terms: Physics - Optics, Electrical Engineering and Systems Science - Image and Video Processing, Physics - Biological Physics

Access URL: http://arxiv.org/abs/2311.00089

MAI-SIM: interferometric multicolor structured illumination microscopy for everybody

Authors: Ward, Edward N., Hecker, Lisa, Christensen, Charles N., Lamb, Jacob R, Lu, Meng, Mascheroni, Luca, Chung, Chyi Wei, Wang, Anna, Rowlands, Christopher J., Schierle, Gabriele S. Kaminski, Kaminski, Clemens F.

Subject Terms: Physics - Instrumentation and Detectors, Physics - Biological Physics, Physics - Optics

Access URL: http://arxiv.org/abs/2206.00532

Fluorescent Nanoparticles for Super-Resolution Imaging

Authors: Li, Wei, Schierle, Gabriele S. Kaminski, Lei, Bingfu, Liu, Yingliang, Kaminski, Clemens F.

Source: Chemical reviews. 122(15):12495-12543

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631440512&indx=1&recIds=ETOCRN631440512

Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry Approach to Correlate Local Structure and Aggregation in α-Synuclein

Authors: Seetaloo, Neeleema, Zacharopoulou, Maria, Stephens, Amberley D., Schierle, Gabriele S. Kaminski, Phillips, Jonathan J.

Source: Analytical chemistry. 94(48):16711-16719

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630849432&indx=1&recIds=ETOCRN630849432

Intracellular Aβ42 Aggregation Leads to Cellular Thermogenesis

Authors: Chung, Chyi Wei, Stephens, Amberley D., Konno, Tasuku, Ward, Edward, Avezov, Edward, Kaminski, Clemens F., Hassanali, Ali A., Schierle, Gabriele S. Kaminski

Source: Journal of the American Chemical Society. 144(22):10034-10041

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629476488&indx=1&recIds=ETOCRN629476488

Label-Free Characterization of Amyloids and Alpha-Synuclein Polymorphs by Exploiting Their Intrinsic Fluorescence Property

Authors: Chung, Chyi Wei, Stephens, Amberley D., Ward, Edward, Feng, Yuqing, Davis, Molly Jo, Kaminski, Clemens F., Schierle, Gabriele S. Kaminski

Source: Analytical chemistry. 94(13):5367-5374

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629077502&indx=1&recIds=ETOCRN629077502

Short hydrogen bonds enhance nonaromatic protein-related fluorescence

Authors: Stephens, Amberley D., Qaisrani, Muhammad Nawaz, Ruggiero, Michael T., Mirón, Gonzalo Díaz, Morzan, Uriel N., Lebrero, Mariano C. González, Jones, Saul T. E., Poli, Emiliano, Bond, Andrew D., Woodhams, Philippa J., Kleist, Elyse M., Grisanti, Luca, Gebauer, Ralph, Zeitler, J. Axel, Credgington, Dan, Hassanali, Ali, Schierle, Gabriele S. Kaminski

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 May . 118(21), 1-9.

Access URL: https://www.jstor.org/stable/27040601

Purification of Recombinant α-synuclein: A Comparison of Commonly Used Protocols

Authors: Stephens, Amberley D., Matak-Vinkovic, Dijana, Fernandez-Villegas, Ana, Schierle, Gabriele S. Kaminski

Source: Biochemistry. 59(48):4563-4572

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625411954&indx=1&recIds=ETOCRN625411954

Design of a Functionalized Metal—Organic Framework System for Enhanced Targeted Delivery to Mitochondria

Authors: Haddad, Salame, Lázaro, Isabel Abánades, Fantham, Marcus, Mishra, Ajay, Silvestre-Albero, Joaquin, Osterrieth, Johannes W. M., Schierle, Gabriele S. Kaminski, Kaminski, Clemens F., Forgan, Ross S., Fairen-Jimenez, David

Source: Journal of the American Chemical Society. 142(14):6661-6674

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623795004&indx=1&recIds=ETOCRN623795004

Microelectrode Arrays Measure Blocking of Voltage‐Gated Calcium Ion Channels on Supported Lipid Bilayers Derived from Primary Neurons.

Authors: Lu, Zixuan¹, Barberio, Chiara¹, Fernandez‐Villegas, Ana¹, Withers, Aimee¹, Wheeler, Alexandra¹, Kallitsis, Konstantinos¹, Martinelli, Eleonora¹, Savva, Achilleas¹, Hess, Becky M.², Pappa, Anna‐Maria^1,3,4, Schierle, Gabriele S. Kaminski¹, Owens, Róisín M.¹, rmo37@cam.ac.uk

Source: Advanced Science; 7/17/2024, Vol. 11 Issue 27, p1-15, 15p

Mutation of the ALS-/FTD-Associated RNA-Binding Protein FUS Affects Axonal Development.

Authors: van Tartwijk, Francesca W., Wunderlich, Lucia C. S., Mela, Ioanna, Makarchuk, Stanislaw, Jakobs, Maximilian A. H., Qamar, Seema, Franze, Kristian, Schierle, Gabriele S. Kaminski, St George-Hyslop, Peter H., Qiaojin Lin, Julie, Holt, Christine E., Kaminski, Clemens F.

Source: Journal of Neuroscience; 7/3/2024, Vol. 44 Issue 27, p1-13, 13p

Subject Terms: RNA-binding proteins, ATOMIC force microscopy, AMYOTROPHIC lateral sclerosis, FRONTOTEMPORAL dementia

Different Structural Conformers of Monomeric α-Synuclein Identified after Lyophilizing and Freezing

Authors: Stephens, Amberley D., Nespovitaya, Nadezhda, Zacharopoulou, Maria, Kaminski, Clemens F., Phillips, Jonathan J., Schierle, Gabriele S. Kaminski

Source: Analytical chemistry. 90(11):6975-6983

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN616265920&indx=1&recIds=ETOCRN616265920

Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons

Authors: Pinotsi, Dorothea, Michel, Claire H., Buell, Alexander K., Laine, Romain F., Mahou, Pierre, Dobson, Christopher M., Kaminski, Clemens F., Schierle, Gabriele S. Kaminski

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Apr 01. 113(14), 3815-3819.

Access URL: https://www.jstor.org/stable/26469184

ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

Authors: Murakami, Tetsuro, Qamar, Seema, Lin, Julie Qiaojin, Schierle, Gabriele S. Kaminski, Rees, Eric, Miyashita, Akinori, Costa, Ana R., Dodd, Roger B., Chan, Fiona T.S., Michel, Claire H., Kronenberg-Versteeg, Deborah, Li, Yi, Yang, Seung-Pil, Wakutani, Yosuke, Meadows, William, Ferry, Rodylyn Rose, Dong, Liang, Tartaglia, Gian Gaetano, Favrin, Giorgio, Lin, Wen-Lang, Dickson, Dennis W., Zhen, Mei, Ron, David, Schmitt-Ulms, Gerold, Fraser, Paul E., Shneider, Neil A., Holt, Christine, Vendruscolo, Michele, Kaminski, Clemens F., St George-Hyslop, Peter

Source: In Neuron 18 November 2015 88(4):678-690

Optical Super-Resolution Imaging of β-Amyloid Aggregation In Vitro and In Vivo: Method and Techniques

Authors: Pinotsi, Dorothea, Schierle, Gabriele S. Kaminski, Kaminski, Clemens F.

Source: Methods in molecular biology. 1303:125-142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN602446704&indx=1&recIds=ETOCRN602446704

Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity

Authors: Stephens, Amberley D., Zacharopoulou, Maria, Moons, Rani, Fusco, Giuliana, Seetaloo, Neeleema, Chiki, Anass, Woodhams, Philippa J., Mela, Ioanna, Lashuel, Hilal A., Phillips, Jonathan J., De Simone, Alfonso, Sobott, Frank, Schierle, Gabriele S. Kaminski

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174599620.0x000001&indx=1&recIds=ETOCvdc_100174599620.0x000001

Catalytic and chaperone-like functions in an intrinsically disordered protein associated with desiccation tolerance

Authors: Chakrabortee, Sohini, Meersman, Filip, Schierle, Gabriele S. Kaminski, Bertoncini, Carlos W., McGee, Brian, Kaminski, Clemens F., Tunnacliffe, Alan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Sep . 107(37), 16084-16089.

Access URL: https://www.jstor.org/stable/20779620

C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction

Authors: Lautenschläger, Janin, Stephens, Amberley D., Fusco, Giuliana, Ströhl, Florian, Curry, Nathan, Zacharopoulou, Maria, Michel, Claire H., Laine, Romain, Nespovitaya, Nadezhda, Fantham, Marcus, Pinotsi, Dorothea, Zago, Wagner, Fraser, Paul, Tandon, Anurag, St George-Hyslop, Peter, Rees, Eric, Phillips, Jonathan J., De Simone, Alfonso, Kaminski, Clemens F., Schierle, Gabriele S. Kaminski

Source: Nature communications. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129927143.0x000001&indx=1&recIds=ETOCvdc_100129927143.0x000001

Machine learning assisted interferometric structured illumination microscopy for dynamic biological imaging.

Authors: Ward, Edward N., Hecker, Lisa, Christensen, Charles N., Lamb, Jacob R., Lu, Meng, Mascheroni, Luca, Chung, Chyi Wei, Wang, Anna, Rowlands, Christopher J., Schierle, Gabriele S. Kaminski, Kaminski, Clemens F.

Source: Nature Communications; 12/21/2022, Vol. 13 Issue 1, p1-10, 10p

Subject Terms: MACHINE learning, MICROSCOPY, MORPHOLOGY, LIGHTING, CELL imaging

Structure-Specific Intrinsic Fluorescence of Protein Amyloids Used to Study their Kinetics of Aggregation

Authors: Chan, Fiona T.S, Pinotsi, Dorothea, Schierle, Gabriele S. Kaminski, Kaminski, Clemens F

Source: Bio-Nanoimaging: Protein Misfolding and Aggregation. 2014, p147-155.