High throughput generation of a resource of the human secretome in mammalian cells

Authors: Tegel, Hanna, Dannemeyer, Melanie, Kanje, Sara, Sivertsson, Åsa, Berling, Anna, Svensson, Anne-Sophie, Hober, Andreas, Enstedt, Henric, Volk, Anna-Luisa, Lundqvist, Magnus, Moradi, Mona, Afshari, Delaram, Ekblad, Siri, Xu, LanLan, Westin, Malin, Bidad, Faranak, Schiavone, Lovisa Holmberg, Davies, Rick, Mayr, Lorenz M., Knight, Sinead, Göpel, Sven O., Voldborg, Björn G., Edfors, Fredrik, Forsström, Björn, von Feilitzen, Kalle, Zwahlen, Martin, Rockberg, Johan, Takanen, Jenny Ottosson, Uhlén, Mathias, Hober, Sophia

Source: New biotechnology. 58:45-54

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116063233.0x000001&indx=1&recIds=ETOCvdc_100116063233.0x000001

Secretome-Based Screening in Target Discovery

Authors: Ding, Mei, Tegel, Hanna, Sivertsson, Åsa, Hober, Sophia, Snijder, Arjan, Ormö, Mats, Strömstedt, Per-Erik, Davies, Rick, Schiavone, Lovisa Holmberg

Source: SLAS discovery. 25(6):535-551

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623884014&indx=1&recIds=ETOCRN623884014

An image-based screen for secreted proteins involved in breast cancer G0 cell cycle arrest.

Authors: Weston, William A., Holt, Jordan A., Wiecek, Anna J., Pilling, James, Schiavone, Lovisa Holmberg, Smith, David M., Secrier, Maria, Barr, Alexis R.

Source: Scientific Data; 8/10/2024, Vol. 11 Issue 1, p1-10, 10p

Subject Terms: CELL proliferation, BREAST cancer, CELL cycle, EPITHELIAL cells, CANCER cells, BREAST

The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer

Authors: Jansson, Anna M., Csiszar, Agnes, Maier, Joachim, Nyström, Ann-Christin, Ax, Elisabeth, Johansson, Patrik, Schiavone, Lovisa Holmberg

Source: In Journal of Biological Chemistry 15 September 2017 292(37):15501-15511

Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression.

Authors: Ma, Tianfang, Jin, Lianjin, Bai, Shanshan, Liu, Zhan, Wang, Shuo, Shen, Beibei, Cho, Yeyoung, Cao, Subing, Sun, Meijuan J S, Fazli, Ladan, Zhang, David, Wedderburn, Chiyaro, Zhang, Derek Y, Mugon, Gavisha, Ungerleider, Nathan, Baddoo, Melody, Zhang, Kun, Schiavone, Lovisa Holmberg, Burkhardt, Brant R, Fan, Jia

Source: JNCI: Journal of the National Cancer Institute; Mar2024, Vol. 116 Issue 3, p421-433, 13p

Subject Terms: ANDROGEN receptors, PROSTATE cancer, CANCER invasiveness, GENETIC models, GENE expression, CHROMOSOMAL rearrangement, GENE enhancers

The Flexible N-terminal Domain of Ribosomal Protein L11 from Escherichia coli Is Necessary for the Activation of Stringent Factor

Authors: Jenvert, Rose-Marie, Schiavone, Lovisa Holmberg

Source: In Journal of Molecular Biology 19 January 2007 365(3):764-772

Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP

Authors: Högbom, Martin ^†, Collins, Ruairi ^†, van den Berg, Susanne, Jenvert, Rose-Marie, Karlberg, Tobias, Kotenyova, Tetyana, Flores, Alex, Hedestam, Gunilla B. Karlsson, Schiavone, Lovisa Holmberg

Source: In Journal of Molecular Biology 2007 372(1):150-159

Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.

Authors: Ding, Mei, Malhotra, Rajneesh, Ottosson, Tomas, Lundqvist, Magnus, Mebrahtu, Aman, Brengdahl, Johan, Gehrmann, Ulf, Bäck, Elisabeth, Ross-Thriepland, Douglas, Isaksson, Ida, Magnusson, Björn, Sachsenmeier, Kris F., Tegel, Hanna, Hober, Sophia, Uhlén, Mathias, Mayr, Lorenz M., Davies, Rick, Rockberg, Johan, Schiavone, Lovisa Holmberg

Source: Scientific Reports; 8/18/2021, Vol. 11 Issue 1, p1-13, 13p

Subject Terms: IMMUNOMODULATORS, T cells, IMMUNE response, TRANSCRIPTOMES, CELL survival, FLOW cytometry

FAM3B PANDER and FAM3C ILEI Represent a Distinct Class of Signaling Molecules with a Non-Cytokine-like Fold

Authors: Johansson, Patrik, Bernström, Jenny, Gorman, Tracy, Öster, Linda, Bäckström, Stefan, Schweikart, Fritz, Xu, Bingze, Xue, Yafeng, Schiavone, Lovisa Holmberg

Source: In Structure 5 February 2013 21(2):306-313

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Mapping the interaction of SmpB with ribosomes by footprinting of ribosomal RNA.

Authors: Ivanova, Natalia, Pavlov, Michael Y., Bouakaz, Elli, Ehrenberg, Måns, Schiavone, Lovisa Holmberg

Source: Nucleic Acids Research; Jun2005, Vol. 33 Issue 11, p3529-3539, 11p