Unlocking the potential of Molecular Tumor Boards: from cutting-edge data interpretation to innovative clinical pathways

Authors: Pastò, Brenno, Buzzatti, Giulia, Schettino, Clorinda, Malapelle, Umberto, Bergamini, Alice, De Angelis, Carmine, Musacchio, Lucia, Dieci, Maria Vittoria, Kuhn, Elisabetta, Lambertini, Matteo, Passarelli, Anna, Toss, Angela, Farolfi, Alberto, Roncato, Rossana, Capoluongo, Ettore, Vida, Riccardo, Pignata, Sandro, Callari, Maurizio, Baldassarre, Gustavo, Bartoletti, Michele, Gerratana, Lorenzo, Puglisi, Fabio

Source: In Critical Reviews in Oncology / Hematology July 2024 199

Carboplatin and paclitaxel plus avelumab compared with carboplatin and paclitaxel in advanced or recurrent endometrial cancer (MITO END-3): a multicentre, open-label, randomised, controlled, phase 2 trial

Authors: Pignata, Sandro, Scambia, Giovanni, Schettino, Clorinda, Arenare, Laura, Pisano, Carmela, Lombardi, Davide, De Giorgi, Ugo, Andreetta, Claudia, Cinieri, Saverio, De Angelis, Carmine, Priolo, Domenico, Casanova, Claudia, Rosati, Marta, Greco, Filippo, Zafarana, Elena, Schiavetto, Ilaria, Mammoliti, Serafina, Cecere, Sabrina Chiara, Salutari, Vanda, Scalone, Simona, Farolfi, Alberto, Di Napoli, Marilena, Lorusso, Domenica, Gargiulo, Piera, Califano, Daniela, Russo, Daniela, Spina, Anna, De Cecio, Rossella, Chiodini, Paolo, Perrone, Francesco

Source: Lancet oncology. 24(3):286-296

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186450013.0x000001&indx=1&recIds=ETOCvdc_100186450013.0x000001

A fully virtual and nationwide molecular tumor board for gynecologic cancer patients: the virtual experience of the MITO cooperative group

Authors: Bartoletti, Michele ¹, Bergamini, Alice ², Giannone, Gaia ^{3, 4}, Nero, Camilla ⁵, Musacchio, Lucia ⁵, Farolfi, Alberto ⁶, Passarelli, Anna ⁷, Kuhn, Elisabetta ^{8, 9}, Castaldo, Daniele ¹⁰, Lombardo, Valentina ¹¹, Di Palma, Teresa ¹², Lorusso, Domenica ^{5, 13}, Puglisi, Fabio ^{1, 14}, De Giorgi, Ugo ⁶, Valabrega, Giorgio ³, Schettino, Clorinda ¹⁵, Scambia, Giovanni ^{5, 13}, Capoluongo, Ettore ¹⁶, Pignata, Sandro ^{7, *}

Source: In International Journal of Gynecological Cancer September 2022 32(9):1205-1207

Olaparib beyond progression compared with platinum chemotherapy after secondary cytoreductive surgery in patients with recurrent ovarian cancer: phase III randomized, open-label MITO 35b study, a project of the MITO-MANGO groups

Authors: Schettino, Clorinda ¹, Musacchio, Lucia ², Bartoletti, Michele ³, Chiodini, Paolo ⁴, Arenare, Laura ¹, Baldassarre, Gustavo ⁵, Califano, Daniela ⁶, Capoluongo, Ettore ^{7, 8}, Costi, Maria Paola ⁹, D'Incalci, Maurizio ^{10, 11}, Marchini, Sergio ¹¹, Mezzanzanica, Delia ¹², Normanno, Nicola ¹³, Scala, Stefania ⁶, Greggi, Stefano ¹⁴, Perrone, Francesco ¹, Pignata, Sandro ^{15, *}

Source: In International Journal of Gynecological Cancer June 2022 32(6):799-803

Thromboembolic events and antithrombotic prophylaxis in advanced ovarian cancer patients treated with bevacizumab: secondary analysis of the phase IV MITO-16A/MaNGO-OV2A trial

Authors: Di Liello, Raimondo ¹, Arenare, Laura ¹, Raspagliesi, Francesco ², Scambia, Giovanni ³, Pisano, Carmela ⁴, Colombo, Nicoletta ⁵, Frezzini, Simona ⁶, Tognon, Germana ⁷, Artioli, Grazia ⁸, Gadducci, Angiolo ⁹, Lauria, Rossella ¹⁰, Ferrero, Annamaria ¹¹, Cinieri, Saverio ¹², De Censi, Andrea ¹³, Breda, Enrico ¹⁴, Scollo, Paolo ¹⁵, De Giorgi, Ugo ¹⁶, Lissoni, Andrea Alberto ¹⁷, Katsaros, Dionyssios ¹⁸, Lorusso, Domenica ¹⁹, Salutari, Vanda ³, Cecere, Sabrina Chiara ⁴, Lapresa, Mariateresa ¹⁹, Nardin, Margherita ⁶, Bogani, Giorgio ², Distefano, Mariagrazia ³, Greggi, Stefano ²⁰, Gargiulo, Piera ¹, Schettino, Clorinda ¹, Gallo, Ciro ²¹, Daniele, Gennaro ²², Califano, Daniela ²³, Perrone, Francesco ¹, Pignata, Sandro ⁴, Piccirillo, Maria Carmela ^{1, *}

Source: In International Journal of Gynecological Cancer October 2021 31(10):1348-1355

Homologous Recombination Repair Status In Advanced Endometrial Cancer. An Exploratory Biomarker Analysis From The Randomized, Phase II MITO END 3 Trial

Authors: Bartoletti, Michele ¹, Farolfi, Alberto ², Passarelli, Anna ³, Scambia, Giovanni ⁴, Andreetta, Claudia ⁵, Tamberi, Stefano ⁶, Lorusso, Domenica ⁷, Pisano, Carmela ³, Califano, Daniela ³, De Angelis, Carmine ⁸, Greco, Filippo ⁹, De Cecio, Rossella ³, Scaglione, Giovanni Luca ¹⁰, Spina, Anna ³, Ghizzoni, Viola ⁴, Cinieri, Saverio ¹¹, Arenare, Laura ³, Schettino, Clorinda ³, Perrone, Franco ³, Pignata, Sandro ³

Source: In International Journal of Gynecological Cancer February 2025 35(2) Supplement 1

Prognostic role of chemotherapy-induced neutropenia in first-line treatment of advanced ovarian cancer. A pooled analysis of MITO2 and MITO7 trials

Authors: Daniele, Gennaro, Arenare, Laura, Scambia, Giovanni, Pisano, Carmela, Sorio, Roberto, Breda, Enrico, De Placido, Sabino, Savarese, Antonella, Ferrandina, Gabriella, Raspagliesi, Francesco, Panici, Pierluigi Benedetti, Ferro, Antonella, Rimanti, Anita, Cormio, Gennaro, Lorusso, Domenica, Cecere, Sabrina Chiara, Scalone, Simona, Marsico, Valentina Angela, Cardalesi, Cinzia, Cognetti, Francesco, Salutari, Vanda, Attademo, Laura, Guizzaro, Lorenzo, Schettino, Clorinda, Piccirillo, Maria Carmela, Perrone, Francesco, Gallo, Ciro, Pignata, Sandro

Source: In Gynecologic Oncology July 2019 154(1):83-88

Irreversible EGFR Inhibitors in the Treatment of Advanced NSCLC

Authors: Maione, Paolo, Rossi, Antonio, Bareschino, Marianna, Sacco, Paola Claudia, Schettino, Clorinda, Casaluce, Francesca, Sgambato, Assunta, Gridelli, Cesare

Source: Current pharmaceutical design. 20(24):3894-3900

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100048272859.0x000001&indx=1&recIds=ETOCvdc_100048272859.0x000001

Biological and clinical impact of membrane EGFR expression in a subgroup of OC patients from the phase IV ovarian cancer MITO-16A/MANGO-OV2A trial.

Authors: Forlani, Luca, De Cecco, Loris, Simeon, Vittorio, Paolini, Biagio, Bagnoli, Marina, Cecere, Sabrina Chiara, Spina, Anna, Citeroni, Eleonora, Bignotti, Eliana, Lorusso, Domenica, Arenare, Laura, Russo, Daniela, De Angelis, Carmine, Ardighieri, Laura, Scognamiglio, Giosuè, Del Sesto, Michele, Tognon, Germana, Califano, Daniela, Schettino, Clorinda, Chiodini, Paolo

Source: Journal of Experimental & Clinical Cancer Research (17569966); 4/11/2023, Vol. 42 Issue 1, p1-17, 17p

Subject Terms: EPIDERMAL growth factor receptors, OSTEOCHONDROSIS, GENE expression profiling, OVARIAN cancer, NEOVASCULARIZATION inhibitors, OVERALL survival, PROGNOSIS

New Molecular Targets in the Treatment of NSCLC

Authors: Schettino, Clorinda, Bareschino, Maria Anna, Sacco, Paola Claudia, Maione, Paolo, Rossi, Antonio, Casaluce, Francesca, Sgambato, Assunta, Gridelli, Cesare

Source: Current pharmaceutical design. 19(30):5333-5343

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083469052.0x000001&indx=1&recIds=ETOCvdc_100083469052.0x000001

The Role of Maintenance Treatment in Advanced Non–Small-Cell Lung Cancer: Reality or Early Second Line?

Authors: Gridelli, Cesare, Rossi, Antonio, Maione, Paolo, Ambrosio, Rita, Barbato, Valentina, Bareschino, Maria Anna, Schettino, Clorinda, Palazzolo, Giovanni, Sacco, Paola Claudia

Source: In Clinical Lung Cancer November 2010 11(6):374-382

The c-Met Inhibitors: A New Class of Drugs in the Battle Against Advanced Nonsmall- Cell Lung Cancer

Authors: Sgambato, Assunta, Casaluce, Francesca, Maione, Paolo, Rossi, Antonio, Rossi, Emanuela, Napolitano, Alba, Palazzolo, Giovanni, Anna Bareschino, Maria, Schettino, Clorinda, Claudia Sacco, Paola, Ciardiello, Fortunato, Gridelli, Cesare

Source: Current pharmaceutical design. 18(37):6155-6168

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083441187.0x000001&indx=1&recIds=ETOCvdc_100083441187.0x000001

Second and third line treatment in non-small cell lung cancer

Authors: Favaretto, Adolfo, Pasello, Giulia, Magro, Cristina, Schettino, Clorinda, Gridelli, Cesare

Source: In Critical Reviews in Oncology and Hematology 2009 71(2):117-126

The use of xenograft models for the selection of cancer treatments with the EGFR as an example

Authors: Troiani, Teresa, Schettino, Clorinda, Martinelli, Erika, Morgillo, Floriana, Tortora, Giampaolo, Ciardiello, Fortunato

Source: In Critical Reviews in Oncology and Hematology 2008 65(3):200-211

Combined chemo-radiotherapy for locally advanced non-small cell lung cancer: Current status and future development

Authors: Guida, Cesare, Maione, Paolo, Rossi, Antonio, Bareschino, Marianna, Schettino, Clorinda, Barzaghi, Domenico, Elmo, Massimo, Gridelli, Cesare

Source: In Critical Reviews in Oncology and Hematology 2008 68(3):222-232

Chapter 33 - EGFR Mutations: Best Results from Second- and Third-Generation Tyrosine Kinase Inhibitors

Authors: Manzo, Anna, Montanino, Agnese, Costanzo, Raffaele, Sandomenico, Claudia, Palumbo, Giuliano, Schettino, Clorinda, Daniele, Gennaro, Morabito, Alessandro, Perrone, Francesco, Piccirillo, Maria Carmela

Source: In Oncogenomics 2019:477-486

Chemotherapy-induced neutropenia and treatment efficacy in advanced non-small-cell lung cancer: a pooled analysis of 6 randomized trials.

Authors: Gargiulo, Piera, Arenare, Laura, Gridelli, Cesare, Morabito, Alessandro, Ciardiello, Fortunato, Gebbia, Vittorio, Maione, Paolo, Spagnuolo, Alessia, Palumbo, Giuliano, Esposito, Giovanna, Della Corte, Carminia Maria, Morgillo, Floriana, Mancuso, Gianfranco, Di Liello, Raimondo, Gravina, Adriano, Schettino, Clorinda, Di Maio, Massimo, Gallo, Ciro, Perrone, Francesco, Piccirillo, Maria Carmela

Source: BMC Cancer; 5/13/2021, Vol. 21 Issue 1, p1-9, 9p

Subject Terms: NON-small-cell lung carcinoma, PROGNOSIS, OVERALL survival, CANCER prognosis, TREATMENT effectiveness, LUNG cancer, CLINICAL trials, ANTINEOPLASTIC agents, NEUTROPENIA, LUNG tumors, RETROSPECTIVE studies, LONGITUDINAL method

Chemotherapy-induced neutropenia and treatment efficacy in advanced non-smallcell lung cancer: a pooled analysis of 6 randomized trials.

Authors: Gargiulo, Piera, Arenare, Laura, Gridelli, Cesare, Morabito, Alessandro, Ciardiello, Fortunato, Gebbia, Vittorio, Maione, Paolo, Spagnuolo, Alessia, Palumbo, Giuliano, Esposito, Giovanna, Della Corte, Carminia Maria, Morgillo, Floriana, Mancuso, Gianfranco, Di Liello, Raimondo, Gravina, Adriano, Schettino, Clorinda, Di Maio, Massimo, Gallo, Ciro, Perrone, Francesco, Carmela Piccirillo, Maria

Source: BMC Cancer; 5/8/2021, Vol. 21 Issue 1, p1-9, 9p

Subject Terms: LUNG cancer, PROGNOSIS, OVERALL survival, TREATMENT effectiveness, NON-small-cell lung carcinoma

The role of panitumumab in metastatic colorectal cancer.

Authors: Bareschino, Maria Anna^1,2, Schettino, Clorinda^1,2, Maione, Paolo², Rossi, Antonio², NicoleIla, Dario², Ciardiello, Fortunato¹, Gridelli, Cesare² cgridelli@libero.it

Source: Cancer Therapy. 2008, Vol. 6 Issue 2, p477-489. 13p. 1 Diagram, 4 Charts.

Subject Terms: *COLON cancer, *CAUSES of death, *CANCER patients, *VASCULAR endothelial growth factors, *DRUG therapy

Geographic Terms: UNITED States

Company/Entity: UNITED States. Food & Drug Administration

List of Contributors

Authors: Abdelhay, Eliana, Adiseshaiah, Pavan P., Aglietta, Massimo, Allègra, Maryline, Ascierto, Paolo A., Bastus, Nuria Coll, Basudan, Ahmed, Berghuis, A.M. Sofie, Biasco, Guido, Binato, Renata, Borah, Ankita, Brown, Janet E., Cappelletti, Vera, Chan, Sock Hoai, Chen, Alice P., Chen, Ru, Chénard-Poirier, Maxime, Chicchinelli, Nicoletta, Cives, Mauro, Conte, Pierfranco, Corrêa, Stephany, Costanzo, Raffaele, Coyne, Geraldine O’Sullivan, Cristofanilli, Massimo, Daidone, Maria Grazia, Dammacco, Franco, Daniele, Gennaro, De Nola, Rosalba, Dendooven, Amélie, Di Cosimo, Serena, Di Maio, Massimo, Dieci, Maria Vittoria, D’Ambrosio, Lorenzo, D’Oronzo, Stella, Fehm, Tanja, Fenizia, Francesca, Ferrari, Paola, Ghai, Vikas, Giuliano, Mario, Gopalan, Vinod, Grassi, Paolo, Grignani, Giovanni, Guarneri, Valentina, Gyanchandani, Rekha, Heeke, Simon, Hofman, Paul, Hofman, Véronique, Iannaccone, Alessia, Ilié, Marius, Islam, Farhadul, Iuliani, Michele, Kennedy, Richard, Kozlov, Serguei, Kumar, D. Sakthi, Lam, Alfred King-Yin, Lampignano, Rita, Lauriola, Mattia, Lee, Adrian V., Lee, Inyoul, Leone, Patrizia, Lovero, Domenica, Lu, Yong-Jie, Malapelle, Umberto, Manca, Paolo, Mannavola, Francesco, Manzo, Anna, McCabe, Nuala, Meierjohann, Svenja, Merlini, Alessandra, Michalarea, Vasiliki, Montanino, Agnese, Morabito, Alessandro, Nannini, Margherita, Nawroth, Roman, Neubauer, Hans, Ngeow, Joanne, Nicolini, Andrea, Normanno, Nicola, Palmirotta, Raffaele, Palumbo, Giuliano, Pan, Sheng, Panis, Carolina, Pantano, Francesco, Parkes, Eileen, Pasini, Luigi, Passarelli, Anna, Passiglia, Francesco, Pauwels, Patrick, Pellè, Eleonora, Peng, Hong, Perrone, Francesco, Phuong, Lisa, Piccirillo, Maria Carmela, Piekarz, Richard, Piiper, Albrecht, Pisapia, Pasquale, Priedigkeit, Nolan, Pucci, Michela, Quaresmini, Davide, Quek, Richard, Racanelli, Vito, Rachiglio, Anna Maria, Ratta, Raffaele, Ribelli, Giulia, Rolfo, Christian, Ryan, Joseph, Safa, Ahmad R., Salgado, Roberto, Sandomenico, Claudia, Sangiolo, Dario, Santini, Daniele, Schettini, Francesco, Schettino, Clorinda, Schilling, Bastian, Schoon, Jolanda J., Shimanovsky, Alexei, Silvestris, Erica, Silvestris, Franco, Simonetti, Sonia, Smyth, Elizabeth C., Somasundaram, Nagavalli, Søreide, Kjetil, Strosberg, Jonathan, Swierczewska, Magdalena, Takeshima, Hideyuki, Tonini, Giuseppe, Ushijima, Toshikazu, Vacca, Angelo, Vernaci, Grazia, Verzoni, Elena, Vietsch, Eveline E., Vincenzi, Bruno, Waidmann, Oliver, Wang, Kai, Wang, Xiaosheng, Wasser, Jeffery S., Wellstein, Anton, Wood, Steven L., Xu, Lei, Yamada, Harumi

Source: In Oncogenomics 2019:xv-xx