Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy

Authors: Wang, Chen, Zeng, Qun, Gül, Zeynep Melis, Wang, Sisi, Pick, Robert, Cheng, Phil, Bill, Ruben, Wu, Yan, Naulaerts, Stefan, Barnoud, Coline, Hsueh, Pei-Chun, Moller, Sofie Hedlund, Cenerenti, Mara, Sun, Mengzhu, Su, Ziyang, Jemelin, Stéphane, Petrenko, Volodymyr, Dibner, Charna, Hugues, Stéphanie, Jandus, Camilla, Li, Zhongwu, Michielin, Olivier, Ho, Ping-Chih, Garg, Abhishek D., Simonetta, Federico, Pittet, Mikaël J., Scheiermann, Christoph

Source: In Cell 23 May 2024 187(11):2690-2702

The circadian clock time tunes axonal regeneration

Authors: De Virgiliis, Francesco, Mueller, Franziska, Palmisano, Ilaria, Chadwick, Jessica Sarah, Luengo-Gutierrez, Lucia, Giarrizzo, Angela, Yan, Yuyang, Danzi, Matt Christopher, Picon-Muñoz, Carmen, Zhou, Luming, Kong, Guiping, Serger, Elisabeth, Hutson, Thomas Haynes, Maldonado-Lasuncion, Ines, Song, Yayue, Scheiermann, Christoph, Brancaccio, Marco, Di Giovanni, Simone

Source: In Cell Metabolism 5 December 2023 35(12):2153-2164

Control of lymph node activity by direct local innervation

Authors: De Virgiliis, Francesco, Oliva, Valeria Maria, Kizil, Burak, Scheiermann, Christoph

Source: In Trends in Neurosciences September 2022 45(9):704-712

Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma.

Authors: Sun, Mengzhu, Garnier, Laure, Chevalier, Romane, Roumain, Martin, Wang, Chen, Angelillo, Julien, Montorfani, Julien, Pick, Robert, Brighouse, Dale, Fournier, Nadine, Tarussio, David, Tissot, Stéphanie, Lobaccaro, Jean-Marc, Petrova, Tatiana V., Jandus, Camilla, Speiser, Daniel E., Kopf, Manfred, Pot, Caroline, Scheiermann, Christoph, Homicsko, Krisztian

Source: Nature Communications; 2/1/2025, Vol. 16 Issue 1, p1-22, 22p

Subject Terms: MEDICAL sciences, TREATMENT effectiveness, MYELOID cells, CELL physiology, LIPID metabolism

Neonatal neutrophils exhibit reduced NLRP3 inflammasome activation.

Authors: Wackerbarth, Lou Martha, Seifert, Sonja Birke, Napoli, Matteo, Rohwedder, Ina, Vogl, Thomas, Scheiermann, Christoph, Kolben, Thomas, Nussbaum, Claudia, Pruenster, Monika, Immler, Roland, Sperandio, Markus

Source: Journal of Leukocyte Biology; Feb2025, Vol. 117 Issue 2, p1-6, 6p

Subject Terms: NATURAL immunity, NLRP3 protein, INFLAMMASOMES, NEUTROPHILS, IMMUNE response

Molecular Interactions Between Components of the Circadian Clock and the Immune System

Authors: Hergenhan, Sophia, Holtkamp, Stephan, Scheiermann, Christoph

Source: In Journal of Molecular Biology 29 May 2020 432(12):3700-3713

Time-of-Day-Dependent Trafficking and Function of Leukocyte Subsets

Authors: Pick, Robert, He, Wenyan, Chen, Chien-Sin, Scheiermann, Christoph

Source: In Trends in Immunology June 2019 40(6):524-537

Neural control of tumor immunity.

Authors: Kizil, Burak, De Virgiliis, Francesco, Scheiermann, Christoph

Source: FEBS Journal; Nov2024, Vol. 291 Issue 21, p4670-4679, 10p

Subject Terms: PERIPHERAL nervous system, PARASYMPATHETIC nervous system, NERVOUS system tumors, SYMPATHETIC nervous system, NERVOUS system

Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues

Authors: He, Wenyan, Holtkamp, Stephan, Hergenhan, Sophia Martina, Kraus, Kerstin, de Juan, Alba, Weber, Jasmin, Bradfield, Paul, Grenier, Julien Martin Pierre, Pelletier, Jeoffrey, Druzd, David, Chen, Chien-Sin, Ince, Louise Madeleine, Bierschenk, Susanne, Pick, Robert, Sperandio, Markus, Aurrand-Lions, Michel, Scheiermann, Christoph

Source: In Immunity 18 December 2018 49(6):1175-1190

Lymphocyte Circadian Clocks Control Lymph Node Trafficking and Adaptive Immune Responses

Authors: Druzd, David, Matveeva, Olga, Ince, Louise, Harrison, Ute, He, Wenyan, Schmal, Christoph, Herzel, Hanspeter, Tsang, Anthony H., Kawakami, Naoto, Leliavski, Alexei, Uhl, Olaf, Yao, Ling, Sander, Leif Erik, Chen, Chien-Sin, Kraus, Kerstin, de Juan, Alba, Hergenhan, Sophia Martina, Ehlers, Marc, Koletzko, Berthold, Haas, Rainer, Solbach, Werner, Oster, Henrik, Scheiermann, Christoph

Source: In Immunity 17 January 2017 46(1):120-132

Circadian Rhythms in Anticancer Immunity: Mechanisms and Treatment Opportunities.

Authors: Pick, Robert, Wang, Chen, Zeng, Qun, Gül, Zeynep Melis, Scheiermann, Christoph

Source: Annual Review of Immunology; Apr2024, Vol. 42 Issue 1, p83-102, 17p

Circadian Effects on Vascular Immunopathologies.

Authors: Qun Zeng, Oliva, Valeria Maria, Moro, María Ángeles, Scheiermann, Christoph

Source: Circulation Research; 3/15/2024, Vol. 134 Issue 6, p791-809, 19p

Some Monocytes Got Rhythm

Authors: Druzd, David, Scheiermann, Christoph

Source: Science, 2013 Sep . 341(6153), 1462-1464.

Access URL: http://dx.doi.org/10.1126/science.1244445

Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice

Authors: Almeida, Camila Bononi, Scheiermann, Christoph, Jang, Jung-Eun, Prophete, Colette, Costa, Fernando Ferreira, Conran, Nicola, Frenette, Paul S.

Source: In Blood 4 October 2012 120(14):2879-2888

Adrenergic Nerves Govern Circadian Leukocyte Recruitment to Tissues

Authors: Scheiermann, Christoph, Kunisaki, Yuya, Lucas, Daniel, Chow, Andrew, Jang, Jung-Eun, Zhang, Dachuan, Hashimoto, Daigo, Merad, Miriam, Frenette, Paul S.

Source: In Immunity 24 August 2012 37(2):290-301

Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis

Authors: Gaertner, Florian, Ishikawa-Ankerhold, Hellen, Stutte, Susanne, Fu, Wenwen, Weitz, Jutta, Dueck, Anne, Nelakuditi, Bhavishya, Fumagalli, Valeria, van den Heuvel, Dominic, Belz, Larissa, Sobirova, Gulnoza, Zhang, Zhe, Titova, Anna, Navarro, Alejandro Martinez, Pekayvaz, Kami, Lorenz, Michael, von Baumgarten, Louisa, Kranich, Jan, Straub, Tobias, Popper, Bastian, Zheden, Vanessa, Kaufmann, Walter Anton, Guo, Chenglong, Piontek, Guido, von Stillfried, Saskia, Boor, Peter, Colonna, Marco, Clauß, Sebastian, Schulz, Christian, Brocker, Thomas, Walzog, Barbara, Scheiermann, Christoph, Aird, William C., Nerlov, Claus, Stark, Konstantin, Petzold, Tobias, Engelhardt, Stefan, Sixt, Michael, Hauschild, Robert, Rudelius, Martina, Oostendorp, Robert A. J., Iannacone, Matteo, Heinig, Matthias, Massberg, Steffen

Source: Nature; 20240101, Issue: Preprints p1-9, 9p

Expression and Function of Junctional Adhesion Molecule-C in Myelinated Peripheral Nerves

Authors: Scheiermann, Christoph, Meda, Paolo, Aurrand-Lions, Michel, Madani, Rime, Yiangou, Yiangos, Coffey, Peter, Salt, Thomas E., Ducrest-Gay, Dominique, Caille, Dorothée, Howell, Owain, Reynolds, Richard, Lobrinus, Alexander, Adams, Ralf H., Yu, Alan S. L., Anand, Praveen, Imhof, Beat A., Nourshargh, Sussan

Source: Science, 2007 Nov . 318(5855), 1472-1475.

Access URL: https://www.jstor.org/stable/20051715

JAM-C regulates unidirectional monocyte transendothelial migration in inflammation

Authors: Bradfield, Paul F., Scheiermann, Christoph, Nourshargh, Sussan, Ody, Christiane, Luscinskas, Francis W., Rainger, G. Ed, Nash, Gerard B., Miljkovic-Licina, Marijana, Aurrand-Lions, Michel, Imhof, Beat A. ^*

Source: In Blood 1 October 2007 110(7):2545-2555

JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration

Authors: Woodfin, Abigail, Reichel, Christoph Andreas, Khandoga, Andrej, Corada, Monica, Voisin, Mathieu-Benoit, Scheiermann, Christoph, Haskard, Dorian O., Dejana, Elisabetta, Krombach, Fritz, Nourshargh, Sussan ^*

Source: In Blood 15 September 2007 110(6):1848-1856

ICAM-2 mediates neutrophil transmigration in vivo: evidence for stimulus specificity and a role in PECAM-1–independent transmigration

Authors: Huang, Miao-Tzu, Larbi, Karen Y., Scheiermann, Christoph, Woodfin, Abigail, Gerwin, Nicole, Haskard, Dorian O., Nourshargh, Sussan ^*

Source: In Blood 15 June 2006 107(12):4721-4727