Renal Recovery for Patients with ANCA-Associated Vasculitis and Low eGFR in the ADVOCATE Trial of Avacopan

Authors: Cortazar, Frank B., Niles, John L., Jayne, David R.W., Merkel, Peter A., Bruchfeld, Annette, Yue, Huibin, Schall, Thomas J., Bekker, Pirow

Source: Kidney international reports. 8(4):860-870

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190024959.0x000001&indx=1&recIds=ETOCvdc_100190024959.0x000001

Renal Recovery for Patients with ANCA-Associated Vasculitis and Low eGFR in the ADVOCATE Trial of Avacopan

Authors: Peh, C. Au, Chakera, A., Cooper, B., Kurtkoti, J., Langguth, D., Levidiotis, V., Luxton, G., Mount, P., Mudge, D., Noble, E., Phoon, R., Ranganathan, D., Ritchie, A., Ryan, J., Suranyi, M., Rosenkranz, A., Lhotta, K., Kronbichler, A., Demoulin, N., Bovy, C., Hellemans, R., Hougardy, J., Sprangers, B., Wissing, K., Pagnoux, C., Barbour, S., Brachemi, S., Cournoyer, S., Girard, L., Laurin, L., Liang, P., Philibert, D., Walsh, M., Tesar, V., Becvar, R., Horak, P., Rychlik, I., Szpirt, W., Dieperink, H., Gregersen, J., Ivarsen, P., Krarup, E., Lyngsoe, C., Rigothier, C., Augusto, J., Belot, A., Chauveau, D., Cornec, D., Jourde-Chiche, N., Ficheux, M., Karras, A., Klein, A., Maurier, F., Mesbah, R., Moranne, O., Neel, A., Quemeneur, T., Saadoun, D., Terrier, B., Zaoui, P., Schaier, M., Benck, U., Bergner, R., Busch, M., Floege, J., Grundmann, F., Haller, H., Haubitz, M., Hellmich, B., Henes, J., Hohenstein, B., Hugo, C., Iking-Konert, C., Arndt, F., Kubacki, T., Kotter, I., Lamprecht, P., Lindner, T., Halbritter, J., Mehling, H., Schönermarck, U., Venhoff, N., Vielhauer, V., Witzke, O., Szombati, I., Szucs, G., Garibotto, G., Alberici, F., Brunetta, E., Dagna, L., De Vita, S., Emmi, G., Gabrielli, A., Manenti, L., Pieruzzi, F., Roccatello, D., Salvarani, C., Dobashi, H., Atsumi, T., Fujimoto, S., Hagino, N., Ihata, A., Kaname, S., Kaneko, Y., Katagiri, A., Katayama, M., Kirino, Y., Kitagawa, K., Komatsuda, A., Kono, H., Kurasawa, T., Matsumura, R., Mimura, T., Morinobu, A., Murakawa, Y., Naniwa, T., Nanki, T., Ogawa, N., Oshima, H., Sada, K., Sugiyama, E., Takeuchi, T., Taki, H., Tamura, N., Tsukamoto, T., Yamagata, K., Yamamura, M., van Daele, P., Rutgers, A., Teng, Y., Walker, R., Chua, I., Collins, M., Rabindranath, K., de Zoysa, J., Svensson, M., Grevbo, B., Kalstad, S., Little, M., Clarkson, M., Molloy, E., Pamplona, I. Agraz, Anton, J., Lucia, V. Barrio, Ciggaran, S., Cid, M. Cinta, Encarnacion, M. Diaz, Oliveras, X. Fulladosa, Soler, M. Jose, Rusinol, H. Marco, Praga, M., Porras, L. Quintana, Segarra, A., Bruchfeld, A., Segelmark, M., Soveri, I., Thomaidi, E., Westman, K., Neumann, T., Burnier, M., Daikeler, T., Dudler, J., Hauser, T., Seeger, H., Vogt, B., Jayne, D., Burton, J., Al Jayyousi, R., Amin, T., Andrews, J., Baines, L., Brogan, P., Dasgupta, B., Doulton, T., Flossmann, O., Griffin, S., Harper, J., Harper, L., Kidder, D., Klocke, R., Lanyon, P., Luqmani, R., McLaren, J., Makanjuola, D., McCann, L., Nandagudi, A., Selvan, S., O'Riordan, E., Patel, M., Patel, R., Pusey, C., Rajakariar, R., Robson, J., Robson, M., Salama, A., Smyth, L., Sznajd, J., Taylor, J., Merkel, P., Sreih, A., Belilos, E., Bomback, A., Carlin, J., Chen Lin, Y. Chang, Derebail, V., Dragoi, S., Dua, A., Forbess, L., Geetha, D., Gipson, P., Gohh, R., Greenwood, G.T., Hugenberg, S., Jimenez, R., Kaskas, M., Kermani, T., Kivitz, A., Koening, C., Langford, C., Marder, G., Mohamed, A., Monach, P., Neyra, N., Niemer, G., Niles, J., Obi, R., Owens, C., Parks, D., Podoll, A., Rovin, B., Sam, R., Shergy, W., Silva, A., Specks, U., Spiera, R., Springer, J., Striebich, C., Swarup, A., Thakar, S., Tiliakos, A., Tsai, Y., Waguespack, D., Wasko, M. Chester, Cortazar, Frank B., Niles, John L., Jayne, David R.W., Merkel, Peter A., Bruchfeld, Annette, Yue, Huibin, Schall, Thomas J., Bekker, Pirow

Source: In Kidney International Reports April 2023 8(4):860-870

C5aR expression in kidney tubules, macrophages and fibrosis.

Authors: Dunlap, Carolyn, Zhao, Niky, Ertl, Linda S., Schall, Thomas J., Sullivan, Kathleen M. C.

Source: Journal of Histotechnology; Mar2025, Vol. 48 Issue 1, p27-45, 19p

Subject Terms: KIDNEY tubules, GENE expression, EXTRACELLULAR matrix, IN situ hybridization, FLOW cytometry

Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

Authors: Wong, Ping-Pui, Muñoz-Félix, José M., Hijazi, Maruan, Kim, Hyojin, Robinson, Stephen D., De Luxán-Delgado, Beatriz, Rodríguez-Hernández, Irene, Maiques, Oscar, Meng, Ya-Ming, Meng, Qiong, Bodrug, Natalia, Dukinfield, Matthew Scott, Reynolds, Louise E., Elia, George, Clear, Andrew, Harwood, Catherine, Wang, Yu, Campbell, James J., Singh, Rajinder, Zhang, Penglie, Schall, Thomas J., Matchett, Kylie P., Henderson, Neil C., Szlosarek, Peter W., Dreger, Sally A., Smith, Sally, Jones, J. Louise, Gribben, John G., Cutillas, Pedro R., Meier, Pascal, Sanz-Moreno, Victoria, Hodivala-Dilke, Kairbaan M.

Source: In Cell 11 June 2020 181(6):1346-1363

CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas

Authors: Flores-Toro, Joseph A., Luo, Defang, Gopinath, Adithya, Sarkisian, Matthew R., Campbell, James J., Charo, Israel F., Singh, Rajinder, Schall, Thomas J., Datta, Meenal, Jain, Rakesh K., Mitchell, Duane A., Harrison, Jeffrey K.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jan . 117(2), 1129-1138.

Access URL: https://www.jstor.org/stable/26896988

Adjunctive Treatment With Avacopan, an Oral C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Authors: Merkel, Peter A., Niles, John, Jimenez, Richard, Spiera, Robert F., Rovin, Brad H., Bomback, Andrew, Pagnoux, Christian, Potarca, Antonia, Schall, Thomas J., Bekker, Pirow, Girard, Louis‐Philippe, Lin, Yih Chang Chen, Marder, Galina, Murphy, Jennifer, Shergy, William, Charles Striebich, Christopher, Swarup, Areena, Tumlin, James

Source: ACR open rheumatology. 2(11):662-671

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110757107.0x000001&indx=1&recIds=ETOCvdc_100110757107.0x000001

Seven structures of atypical chemokine receptor 3 reveal the molecular bases for its promiscuity and signaling bias

Authors: Yen, Yu‐Chen, Schafer, Christopher T., Gustavsson, Martin, Eberle, Stefanie A., Dominik, Pawel K., Deneka, Dawid, Zhang, Penglie, Schall, Thomas J., Kossiakoff, Anthony A., Handel, Tracy M., Tesmer, John J.

Source: FASEB journal. 36

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196487856.0x000001&indx=1&recIds=ETOCvdc_100196487856.0x000001

Cytomegalovirus-Encoded β Chemokine Promotes Monocyte-Associated Viremia in the Host

Authors: Saederup, Noah, Lin, Yu chun, Dairaghi, Daniel J., Schall, Thomas J., Mocarski, Edward S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1999 Sep . 96(19), 10881-10886.

Access URL: https://www.jstor.org/stable/48847

Cytomegalovirus Encodes a Potent α Chemokine

Authors: Dairaghi, Daniel J., Duke, Gregory M., Saederup, Noah, Mocarski, Edward S., Kemble, George W., Schall, Thomas J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1999 Aug . 96(17), 9839-9844.

Access URL: https://www.jstor.org/stable/48642

Enzalutamide and CXCR7 inhibitor combination treatment suppresses cell growth and angiogenic signaling in castration‐resistant prostate cancer models

Authors: Luo, Yong, Azad, Abul Kalam, Karanika, Styliani, Basourakos, Spyridon P., Zuo, Xuemei, Wang, Jianxiang, Yang, Luan, Yang, Guang, Korentzelos, Dimitrios, Yin, Jianhua, Park, Sanghee, Zhang, Penglie, Campbell, James J., Schall, Thomas J., Cao, Guangwen, Li, Likun, Thompson, Timothy C.

Source: International journal of cancer. 142(10):2163-2174

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135786239.0x000001&indx=1&recIds=ETOCvdc_100135786239.0x000001

Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells

Authors: Demir, Ihsan Ekin, Kujundzic, Kristina, Pfitzinger, Paulo L., Saricaoglu, Ömer Cemil, Teller, Steffen, Kehl, Timo, Reyes, Carmen Mota, Ertl, Linda S., Miao, Zhenhua, Schall, Thomas J., Tieftrunk, Elke, Haller, Bernhard, Diakopoulos, Kalliope Nina, Kurkowski, Magdalena U., Lesina, Marina, Krüger, Achim, Algül, Hana, Friess, Helmut, Ceyhan, Güralp O.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Jan 01. 114(1), E85-E94.

Access URL: https://www.jstor.org/stable/26478795

The effect of CCR2 inhibitor CCX140-B on residual albuminuria in patients with type 2 diabetes and nephropathy: a randomised trial

Authors: de Zeeuw, Dick, Bekker, Pirow, Henkel, Elena, Hasslacher, Christopher, Gouni-Berthold, Ioanna, Mehling, Heidrun, Potarca, Antonia, Tesar, Vladimir, Heerspink, Hiddo J Lambers, Schall, Thomas J

Source: In The Lancet Diabetes & Endocrinology September 2015 3(9):687-696

ISN Nexus 2016 Symposia: Translational Immunology in Kidney Disease—The Berlin Roadmap

Authors: Anders, Hans-Joachim, Rovin, Brad, Jayne, David, Brunetta, Paul, Coppo, Rosanna, Davidson, Anne, Devarapu, Satish Kumar, de Zeeuw, Dick, Duffield, Jeremy, Eulberg, Dirk, Fierro, Alberto, Floege, Jürgen, Frese, Steffen, Guillevin, Loïc, Holdsworth, Stephen, Hughes, Jeremy, Kettritz, Ralph, Kluger, Malte, Krebs, Christian, Lapteva, Larissa, Levin, Adeera, Li, Jinhua, Lightstone, Liz, Mack, Matthias, Mansouri, Ladan, McAdoo, Stephen, McKinney, Eoin, Panzer, Ulf, Parikh, Samir, Pusey, Charles, Putterman, Chaim, Rabelink, Ton, Radbruch, Andreas, Rees, Andrew, Reilly, Mary, Reinders, Marlies, Remuzzi, Giuseppe, Ruggenenti, Piero, Sacks, Steven, Schall, Thomas J, Meyer-Schwesinger, Catherine, Sharma, Kumar, Suzuki, Yusuke, Tomas, Nicola M., Zhao, Ming-Hui

Source: Kidney international reports. 1(4):327-339

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Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes

Authors: Sullivan, Timothy J., Miao, Zhenhua, Zhao, Bin N., Ertl, Linda S., Wang, Yu, Krasinski, Antoni, Walters, Matthew J., Powers, Jay P., Dairaghi, Daniel J., Baumgart, Trageen, Seitz, Lisa C., Berahovich, Robert D., Schall, Thomas J., Jaen, Juan C.

Source: In Metabolism November 2013 62(11):1623-1632

Cancer associated fibroblast FAK regulates malignant cell metabolism

Authors: Demircioglu, Fevzi, Wang, Jun, Candido, Juliana, Costa, Ana S. H., Casado, Pedro, de Luxan Delgado, Beatriz, Reynolds, Louise E., Gomez-Escudero, Jesus, Newport, Emma, Rajeeve, Vinothini, Baker, Ann-Marie, Roy-Luzarraga, Marina, Graham, Trevor A., Foster, Julie, Wang, Yu, Campbell, James J., Singh, Rajinder, Zhang, Penglie, Schall, Thomas J., Balkwill, Frances R., Sosabowski, Jane, Cutillas, Pedro R., Frezza, Christian, Sancho, Patricia, Hodivala-Dilke, Kairbaan

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164257895.0x000001&indx=1&recIds=ETOCvdc_100164257895.0x000001

CCR9 inhibition does not interfere with the development of immune tolerance to oral antigens

Authors: Walters, Matthew J., Ebsworth, Karen, Sullivan, Timothy J., Zhang, Penglie, Powers, Jay P., Jaen, Juan C., Schall, Thomas J.

Source: In Immunology Letters March 2013 151(1-2):44-47

CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease

Authors: Dairaghi, Daniel J., Oyajobi, Babatunde O. ^*, Gupta, Anjana, McCluskey, Brandon, Miao, Shichang, Powers, Jay P., Seitz, Lisa C., Wang, Yu, Zeng, Yibin, Zhang, Penglie, Schall, Thomas J., Jaen, Juan C.

Source: In Blood 16 August 2012 120(7):1449-1457

CXCR7 (RDC1) Promotes Breast and Lung Tumor Growth in vivo and Is Expressed on Tumor-Associated Vasculature

Authors: Miao, Zhenhua, Luker, Kathryn E., Summers, Bretton C., Berahovich, Rob, Bhojani, Mahaveer S., Rehemtulla, Alnawaz, Kleer, Celina G., Essner, Jeffrey J., Nasevicius, Aidas, Luker, Gary D., Howard, Maureen C., Schall, Thomas J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2007 Oct 01. 104(40), 15735-15740.

Access URL: https://www.jstor.org/stable/25449208

Characterization of CCX282-B, an Orally Bioavailable Antagonist of the CCR9 Chemokine Receptor, for Treatment of Inflammatory Bowel Disease

Authors: Walters, Matthew J. ^*, Wang, Yu, Lai, Nu, Baumgart, Trageen, Zhao, Bin N., Dairaghi, Daniel J., Bekker, Pirow, Ertl, Linda S., Penfold, Mark E.T., Jaen, Juan C., Keshav, Satish, Wendt, Emily, Pennell, Andrew, Ungashe, Solomon, Wei, Zheng, Wright, J.J. Kim, Schall, Thomas J.

Source: In The Journal of Pharmacology and Experimental Therapeutics October 2010 335(1):61-69

Lymphotactin: A Cytokine That Represents a New Class of Chemokine

Authors: Kelner, Gregory S., Kennedy, Jacqueline, Bacon, Kevin B., Kleyensteuber, Sarah, Largaespada, David A., Jenkins, Nancy A., Copeland, Neal G., Bazan, J. Fernando, Moore, Kevin W., Schall, Thomas J., Zlotnik, Albert

Source: Science, 1994 Nov . 266(5189), 1395-1399.

Access URL: https://www.jstor.org/stable/2884940