In Situ Linker of Protein for the Immobilization on the Carbon-Based Sensor Materials

Authors: Yoo, Jin, Park, Tae Shin, Ko, Hwi Jin, Kim, Myung Jin, Park, Tai Hyun

Source: 2024 IEEE SENSORS SENSORS, 2024 IEEE. :1-4 Oct, 2024

Relation: 2024 IEEE SENSORS

Development of novel neutralizing single-chain fragment variable antibodies against S100A8

Authors: Hamideh Raeisi, Masoumeh Azimirad, Alexandru Schiopu, Amir-Hassan Zarnani, Hamid Asadzadeh Aghdaei, Elham Abdemohamadi, Mohammad Reza Zali, Abbas Yadegar

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-19 (2025)

Subject Terms: S100A8, scFv, Phage display, Inflammation, Apoptosis, Therapeutics, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/7bdab1949a2843a8a7dbe36037f0ab39

Revolutionizing oncology: the role of Artificial Intelligence (AI) as an antibody design, and optimization tools

Authors: Varun Dewaker, Vivek Kumar Morya, Yoo Hee Kim, Sung Taek Park, Hyeong Su Kim, Young Ho Koh

Source: Biomarker Research, Vol 13, Iss 1, Pp 1-54 (2025)

Subject Terms: Cancer, Antibody, Artificial Intelligence, AI, ScFv, CAR-T cell, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2050-7771

Access URL: https://doaj.org/article/1229e7bb115c431abc5e3c105fdd6eb3

The development and application of chimeric antigen receptor natural killer (CAR-NK) cells for cancer therapy: current state, challenges and emerging therapeutic advances

Authors: Pin Yao, Ya-Guang Liu, Gang Huang, Liangchun Hao, Runan Wang

Source: Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-27 (2024)

Subject Terms: Chimeric antigen receptor (CAR), Single-chain variable fragment (scFv), Natural killer cells, Major histocompatibility complex (MHC), Tumor microenvironment (TME), Induced pluripotent stem cell (iPSC), Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3619

Access URL: https://doaj.org/article/4442d43ba4af488c81033163b80f83cb

The effects of anti-lung cancer in nude mice by a fully human single-chain antibody against associated antigen Ts7TMR between A549 cells and Trichinella spiralis

Authors: Taotao Yue, Jinpeng Wang, Fang Liu, Pengtao Gong, Jianhua Li, Xichen Zhang, Nan Zhang

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 300-308 (2024)

Subject Terms: Trichinella spiralis, A549 lung cancer, associated antigens, Ts7TMR, scFv, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

Access URL: https://doaj.org/article/ae2aabe187b741fe8409b557bab6839b

Improvement in the function of self-activating chimeric antigen receptor by replacing the linker sequence

Authors: Taku Kouro, Daisuke Hoshino, Yasunobu Mano, Shoutaro Tsuji, Hidetomo Himuro, Kohzoh Imai, Tetsuro Sasada

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: CAR-T, scFv, tonic signaling, T cell exhaustion, cancer immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1502607/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/df73b34f4aed42eeb7e14a6e5dc2858f

Discovery and in vitro characterization of a human anti-CD36 scFv

Authors: Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: CD36, scFv antibodies, cancer, atherosclerotic cardiovascular disease, phage display, human antibodies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1531171/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/374eb35b5872495d8a24a166f4a59fc1

Investigation on environmental factors contributing to bispecific antibody stability and the reversal of self-associated aggregates

Authors: Nattha Ingavat, Nuruljannah Dzulkiflie, Jia Min Liew, Xinhui Wang, Eunice Leong, Han Ping Loh, Say Kong Ng, Yuansheng Yang, Wei Zhang

Source: Bioresources and Bioprocessing, Vol 11, Iss 1, Pp 1-18 (2024)

Subject Terms: Bispecific antibody, Fab-scFv, Stability, Reversible-self association, Environmental factors, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/2197-4365

Access URL: https://doaj.org/article/aec2e4f2fb0a469f8e69c7c502893e55

Single-Chained Fragment Variable (scFv) Recombinant as a Potential Receptor for SARS-CoV-2 Biosensor Based on Surface Plasmon Resonance (SPR)

Authors: Anshori, I., Nugroho, A.E., Solihin, A., Jessika, J., Yusuf, M., Hartati, Y.W., Sari, S.P., Tohari, T.R., Yuliarto, B., Gumilar, G., Nuraviana, L., Althof, R.R.

Source: 2021 IEEE Sensors Sensors, 2021 IEEE Sensors. :1-4 Oct, 2021

Relation: 2021 IEEE Sensors

Neospora caninum as delivery vehicle for anti-PD-L1 scFv-Fc: A novel approach for cancer immunotherapy

Authors: Clément Riviere, Muna Aljieli, Marie-Noëlle Mévélec, Louis Lantier, Fanny Boursin, Laurie Lajoie, Céline Ducournau, Stéphanie Germon, Nathalie Moiré, Isabelle Dimier-Poisson, Nicolas Aubrey, Anne di Tommaso

Source: Molecular Therapy: Oncology, Vol 33, Iss 2, Pp 200968- (2025)

Subject Terms: MT: Regular Issue, Neospora caninum, antibody fragment, scFv-Fc, secretion, cancer immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950329925000372; https://doaj.org/toc/2950-3299

Access URL: https://doaj.org/article/c501c87df0df4304ac22dbbd81fc09b6

CHO-S expression of a novel human recombinant IgG1 of anti-ALD antibody isolated by phage mutation display

Authors: Li, Guilin ^a, Liu, Jiazhen ^b, Guan, Zhenzhen ^a, Wang, Sujuan ^a, Li, Songrui ^a, Wang, Zhiqiang ^a, Dong, Yanna ^a, Cui, Yamin ^a, Li, Yaya ^a, Zhang, Weitao ^a, Tian, Xiaoping ^a, Zhao, Qiaohui ^{a, ⁎}

Source: In Journal of Immunological Methods April 2025 539

Production and functional analysis of a phage displayed scFv recombinant antibody targeting EGFR/HER2 dimerization domain

Authors: Dabiri, Mina ^{a, b, c}, Tehrani, Mohsen ^{a, b}, Rafiei, Alireza ^{a, b}, Valadan, Reza ^{a, b, ⁎}

Source: In Protein Expression and Purification April 2025 228

The development of a canine single-chain phage antibody library to isolate recombinant antibodies for use in translational cancer research

Authors: Lisowska, Małgorzata ^{1, 10, 11, 12, ∗}, Worrall, Erin G. ^{2, 11}, Zavadil-Kokas, Filip ^{3, 11}, Charlton, Keith ⁵, Murray, Euan ^{2, 4}, Mohtar, M. Aiman ^{2, 9}, Krejcir, Radovan ³, Hrabal, Vaclav ³, Brydon, Jack ², Urionabarrenetxea, Ainhoa Gonzalez ², Saliba, David G. ⁶, Grima, Mariana ⁶, Kalathiya, Umesh ¹, Muller, Petr ³, Krejci, Adam ³, Vojtesek, Borivoj ^{3, 8}, Ball, Kathryn L. ², Fahraeus, Robin ⁴, Argyle, David J. ⁷, Parys, Maciej ⁷, Hupp, Ted R. ^{1, 2}

Source: In Cell Reports Methods 24 March 2025 5(3)

Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer

Authors: Du, Weijie ^{1, 2}, Noyan, Fatih ³, McCallion, Oliver ⁴, Drosdek, Vanessa ^{1, 2}, Kath, Jonas ^{1, 2}, Glaser, Viktor ^{1, 2}, Fuster-Garcia, Carla ^{5, 6, 7}, Yang, Mingxing ², Stein, Maik ^{1, 2}, Franke, Clemens ^{1, 2}, Pu, Yaolin ^{1, 2}, Weber, Olaf ⁸, Polansky, Julia K. ^{2, 9}, Cathomen, Toni ^{5, 6, 7}, Jaeckel, Elmar ^{3, 10}, Hester, Joanna ⁴, Issa, Fadi ⁴, Volk, Hans-Dieter ^{1, 2, 11}, Schmueck-Henneresse, Michael ^{1, 2}, Reinke, Petra ^{1, 11}, Wagner, Dimitrios L. ^{1, 2, 11, 12, 13, ∗}

Source: In Molecular Therapy 5 March 2025 33(3):997-1013

An engineered palivizumab IgG2 subclass for synthetic gp130 and fas-mediated signaling

Authors: Wittich, Christoph ¹, Ettich, Julia ¹, Hertell, Marcel ¹, Ghosh Roy, Biswadeep ², Xu, Haifeng C. ², Floss, Doreen M. ¹, Lang, Philipp A. ², Scheller, Jürgen ^{1, ∗}

Source: In Journal of Biological Chemistry March 2025 301(3)

Construction and characterization of a novel secreted MsC-CAR-T cell in solid tumors

Authors: Mao, Yuan ^{a, b, c, d, 1}, Chen, Yufeng ^{b, c, e, 1}, Yang, Xiaohui ^{b, c}, He, Yiting ^{b, c, d}, Cui, Daixun ^{b, c}, Huang, Wen ^a, Jiang, Lihua ^a, Zhou, Xiaoli ^f, Chang, Xinxia ^{b, c, d}, Zhu, Jin ^g, Zhu, Yi ⁱ, Tang, Qi ^{b, d, f}, Feng, Zhenqing ^{b, c, d, ∗∗∗∗}, Zhang, Louqian ^{h, ∗∗∗}, Jiang, Kuirong ^{i, ∗∗}, Yuan, Hao ^{i, ∗}

Source: In Cancer Letters 28 February 2025 611

A novel bispecific antibody targeting two overlapping epitopes in RBD improves neutralizing potency and breadth against SARS-CoV-2

Authors: Hancong Sun, Lingyun Xia, Jianhua Li, Yuanyuan Zhang, Guanying Zhang, Ping Huang, Xingxing Wang, Yue Cui, Ting Fang, Pengfei Fan, Qiang Zhou, Xiangyang Chi, Changming Yu

Source: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

Subject Terms: SARS-CoV-2, Omicron subvariants, bispecific antibodies, IgG-(scFv)2, Cryo-EM, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/1d674d777c2e49439ecdb7cb2d869d63

Revolutionizing sexed sorting sperm using scFv antibodies combined with microbeads for porcine sexed semen

Authors: Thongkham, Marninphan ^a, Hongsibsong, Surat ^b, Mekchay, Supamit ^a, Sathanawongs, Anucha ^c, Paitoon, Phanuwit ^a, Saenjaiban, Aphisit ^d, Satsook, Apinya ^e, Jantanasakulwong, Kittisak ^{f, h}, Rachtanapun, Pornchai ^{f, h}, Xu, Zhen-Lin ^g, Sringarm, Korawan ^{a, h, ⁎}

Source: In International Journal of Biological Macromolecules May 2025 308 Part 2

Extracellular vesicles engineered to directly target encephalomyocarditis virus ameliorates multi-organ viremia in a lethal infection model

Authors: Yue, Jiayu ^{a, b, c, 1}, Yang, Yanmei ^{a, b, c, 1}, Idris, Adi ^d, Jin, Wenjing ^{a, b}, Zhang, Yaxin ^{a, b, c}, Chen, Yongfang ^{a, b}, Li, Xiangrong ^{a, b}, Li, Huixia ^{a, b}, Li, Shasha ^{a, b, c}, Wen, Yanqiao ^{a, b, c}, Feng, Ruofei ^{a, b, c, ⁎}, Xie, Jingying ^{a, b, c, ⁎}

Source: In Veterinary Microbiology May 2025 304

Nicotiana benthamiana-derived dupilumab-scFv reaches deep into the cultured human nasal epithelial cells and inhibits CCL26 expression

Authors: Beom Jun Kwon, Na Hyun Cho, Taeyoung Ahn, Geunah Kim, Nguyễn Thị Xuân Diệu, Woo Taek Kim, Hyung-Ju Cho, Dong Hye Seo, Joo Young Kim

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Subject Terms: ScFv, Dupilumab, Nicotiana benthamiana, Human nasal epithelial cell, Non-invasive treatment, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/511d5664a0bf456e8362af26456beb85