Regulation of human interferon signaling by transposon exonization

Authors: Pasquesi, Giulia Irene Maria ^{1, 2}, Allen, Holly ¹, Ivancevic, Atma ¹, Barbachano-Guerrero, Arturo ¹, Joyner, Olivia ¹, Guo, Kejun ³, Simpson, David M. ¹, Gapin, Keala ¹, Horton, Isabella ¹, Nguyen, Lily L. ^{1, 4}, Yang, Qing ^{1, 5}, Warren, Cody J. ^{1, 6}, Florea, Liliana D. ⁷, Bitler, Benjamin G. ⁴, Santiago, Mario L. ³, Sawyer, Sara L. ¹, Chuong, Edward B. ^{1, 2, 8, ∗}

Source: In Cell 26 December 2024 187(26):7621-7636

Structurally divergent and recurrently mutated regions of primate genomes

Authors: Mao, Yafei, Harvey, William T., Porubsky, David, Munson, Katherine M., Hoekzema, Kendra, Lewis, Alexandra P., Audano, Peter A., Rozanski, Allison, Yang, Xiangyu, Zhang, Shilong, Yoo, DongAhn, Gordon, David S., Fair, Tyler, Wei, Xiaoxi, Logsdon, Glennis A., Haukness, Marina, Dishuck, Philip C., Jeong, Hyeonsoo, del Rosario, Ricardo, Bauer, Vanessa L., Fattor, Will T., Wilkerson, Gregory K., Mao, Yuxiang, Shi, Yongyong, Sun, Qiang, Lu, Qing, Paten, Benedict, Bakken, Trygve E., Pollen, Alex A., Feng, Guoping, Sawyer, Sara L., Warren, Wesley C., Carbone, Lucia, Eichler, Evan E.

Source: In Cell 14 March 2024 187(6):1547-1562

Just 2% of SARS-CoV-2—positive individuals carry 90% of the virus circulating in communities

Authors: Yang, Qing, Saldi, Tassa K., Gonzales, Patrick K., Lasda, Erika, Decker, Carolyn J., Tat, Kimngan L., Fink, Morgan R., Hager, Cole R., Davis, Jack C., Ozeroff, Christopher D., Muhlrad, Denise, Clark, Stephen K., Fattor, Will T., Meyerson, Nicholas R., Paige, Camille L., Gilchrist, Alison R., Barbachano-Guerrero, Arturo, Worden-Sapper, Emma R., Wu, Sharon S., Brisson, Gloria R., McQueen, Matthew B., Dowell, Robin D., Leinwand, Leslie, Parker, Roy, Sawyer, Sara L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 May . 118(21), 1-6.

Access URL: https://www.jstor.org/stable/27040652

A metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 species

Authors: Hawkins, John A., Kaczmarek, Maria E., Müller, Marcel A., Drosten, Christian, Press, William H., Sawyer, Sara L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Jun 01. 116(23), 11351-11360.

Access URL: https://www.jstor.org/stable/26706450

A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV)

Authors: Warren, Cody J., Meyerson, Nicholas R., Stabell, Alex C., Fattor, Will T., Wilkerson, Gregory K., Sawyer, Sara L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Jun 01. 116(23), 11460-11469.

Access URL: https://www.jstor.org/stable/26706463

Analyzing Machupo virus-receptor binding by molecular dynamics simulations

Authors: Meyer, Austin G., Sawyer, Sara L., Ellington, Andrew D., Wilke, Claus O.

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/1302.7075

TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation

Authors: Chiramel, Abhilash I., Meyerson, Nicholas R., McNally, Kristin L., Broeckel, Rebecca M., Montoya, Vanessa R., Méndez-Solís, Omayra, Robertson, Shelly J., Sturdevant, Gail L., Lubick, Kirk J., Nair, Vinod, Youseff, Brian H., Ireland, Robin M., Bosio, Catharine M., Kim, Kyusik, Luban, Jeremy, Hirsch, Vanessa M., Taylor, R. Travis, Bouamr, Fadila, Sawyer, Sara L., Best, Sonja M.

Source: In Cell Reports 11 June 2019 27(11):3269-3283

Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication

Authors: Zhang, Junjie, Zhao, Jun, Xu, Simin, Li, Junhua, He, Shanping, Zeng, Yi, Xie, Linshen, Xie, Na, Liu, Ting, Lee, Katie, Seo, Gil Ju, Chen, Lin, Stabell, Alex C., Xia, Zanxian, Sawyer, Sara L., Jung, Jae, Huang, Canhua, Feng, Pinghui

Source: In Cell Host & Microbe 8 August 2018 24(2):234-248

Positive Selection of Primate TRIM5α Identifies a Critical Species-Specific Retroviral Restriction Domain

Authors: Sawyer, Sara L., Wu, Lily I., Emerman, Michael, Malik, Harmit S., Groudine, Mark T.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Feb . 102(8), 2832-2837.

Access URL: https://www.jstor.org/stable/3374707

Nuclear TRIM25 Specifically Targets Influenza Virus Ribonucleoproteins to Block the Onset of RNA Chain Elongation

Authors: Meyerson, Nicholas R., Zhou, Ligang, Guo, Yusong R., Zhao, Chen, Tao, Yizhi J., Krug, Robert M., Sawyer, Sara L.

Source: In Cell Host & Microbe 8 November 2017 22(5):627-638

An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates

Authors: Lou, Dianne I., Kim, Eui Tae, Meyerson, Nicholas R., Pancholi, Neha J., Mohni, Kareem N., Enard, David, Petrov, Dmitri A., Weller, Sandra K., Weitzman, Matthew D., Sawyer, Sara L.

Source: In Cell Host & Microbe 10 August 2016 20(2):178-188

A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction

Authors: Nepveu-Traversy, Marie-Édith, Demogines, Ann, Fricke, Thomas, Plourde, Mélodie B., Riopel, Kathleen, Veillette, Maxime, Diaz-Griffero, Felipe, Sawyer, Sara L., Berthoux, Lionel

Source: In Heliyon January 2016 2(1)

Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility

Authors: White, Tommy E., Brandariz-Nuñez, Alberto, Valle-Casuso, Jose Carlos, Knowlton, Caitlin, Kim, Baek, Sawyer, Sara L., Diaz-Griffero, Felipe

Source: In Virology July 2014 460-461:34-44

RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus.

Authors: Burke, James M.^1,2, james.burke@ufl.edu, Ripin, Nina^1,3, Ferretti, Max B.⁴, St Clair, Laura A.^5,6, Worden-Sapper, Emma R.⁷, Salgado, Fernando², Sawyer, Sara L.⁷, Perera, Rushika^5,6, Lynch, Kristen W.⁴, Parker, Roy^1,3,8, james.burke@ufl.edu

Source: PLoS Pathogens; 11/1/2022, Vol. 18 Issue 11, p1-31, 31p

D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B

Authors: McDougle, Rebecca M., Hultquist, Judd F., Stabell, Alex C., Sawyer, Sara L., Harris, Reuben S.

Source: In Virology 20 June 2013 441(1):31-39

Generation of an HIV Resistant T-cell Line by Targeted “Stacking” of Restriction Factors

Authors: Voit, Richard A, McMahon, Moira A, Sawyer, Sara L, Porteus, Matthew H ^*

Source: In Molecular Therapy April 2013 21(4):786-795

High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing

Authors: Lou, Dianne I., Hussmann, Jeffrey A., McBee, Ross M., Acevedo, Ashley, Andino, Raul, Press, William H., Sawyer, Sara L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Dec 01. 110(49), 19872-19877.

Access URL: https://www.jstor.org/stable/23758326

A cross-species view on viruses

Authors: Sawyer, Sara L, Elde, Nels C

Source: In Current Opinion in Virology October 2012 2(5):561-568

Two-stepping through time: mammals and viruses

Authors: Meyerson, Nicholas R., Sawyer, Sara L.

Source: In Trends in Microbiology 2011 19(6):286-294

Positive Selection of Yeast Nonhomologous End-Joining Genes and a Retrotransposon Conflict Hypothesis

Authors: Sawyer, Sara L., Malik, Harmit S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2006 Nov . 103(47), 17614-17619.

Access URL: https://www.jstor.org/stable/30052511