Molecular Profiling Reveals Novel Gene Fusions and Genetic Markers for Refined Patient Stratification in Pediatric Acute Lymphoblastic Leukemia

Authors: Péterffy, Borbála ^{a, b}, Krizsán, Szilvia ^{a, b, c}, Egyed, Bálint ^{a, b, c}, Bedics, Gábor ^{a, b}, Benard-Slagter, Anne ^d, Palit, Sander ^d, Erdélyi, Dániel János ^c, Müller, Judit ^c, Nagy, Tibor ^{a, b, e}, Hegyi, Lajos László ^{a, b}, Bekő, Anna ^{a, b}, Kenéz, Lili Anna ^{a, b}, Jakab, Zsuzsanna ^f, Péter, György ^g, Zombori, Marianna ^g, Csanádi, Krisztina ^g, Ottóffy, Gábor ^h, Csernus, Katalin ^h, Vojcek, Ágnes ^h, Tiszlavicz, Lilla Györgyi ⁱ, Gábor, Krisztina Mita ⁱ, Kelemen, Ágnes ^j, Hauser, Péter ^j, Kállay, Krisztián ^k, Kertész, Gabriella ^k, Gaál, Zsuzsanna ^l, Szegedi, István ^l, Barna, Gábor ^{a, b}, Márk, Ágnes ^{a, b}, Haltrich, Irén ^c, Hevessy, Zsuzsanna ^m, Ujfalusi, Anikó ^m, Kajtár, Béla ⁿ, Timár, Botond ^{a, b}, Kiss, Csongor ^l, Kriván, Gergely ^k, Matolcsy, András ^{a, b, o}, Savola, Suvi ^d, Kovács, Gábor ^c, Bödör, Csaba ^{a, b}, Alpár, Donát ^{a, b, ∗}

Source: In Modern Pathology June 2025 38(6)

Risk prediction for metastasis of clear cell renal cell carcinoma using digital multiplex ligation‐dependent probe amplification

Authors: Yoshikawa, Yoshie, Yamada, Yusuke, Emi, Mitsuru, Atanesyan, Lilit, Smout, Jan, de Groot, Karel, Savola, Suvi, Nakanishi‐Shinkai, Yukako, Kanematsu, Akihiro, Nojima, Michio, Ohmuraya, Masaki, Hashimoto‐Tamaoki, Tomoko, Yamamoto, Shingo

Source: Cancer science. 113(1):297-307

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139946879.0x000001&indx=1&recIds=ETOCvdc_100139946879.0x000001

The genomic landscape of teenage and young adult T‐cell acute lymphoblastic leukemia

Authors: Mansur, Marcela B., Furness, Caroline L., Nakjang, Sirintra, Enshaei, Amir, Alpar, Donat, Colman, Sue M., Minto, Lynne, Irving, Julie, Poole, Beth V., Noronha, Elda P., Savola, Suvi, Iqbal, Sameena, Gribben, John, Pombo‐de‐Oliveira, Maria S., Ford, Tony M., Greaves, Mel F., Delft, Frederik W.

Source: Cancer medicine. 10(14):4864-4873

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123602318.0x000001&indx=1&recIds=ETOCvdc_100123602318.0x000001

Copy number evolution and its relationship with patient outcome—an analysis of 178 matched presentation-relapse tumor pairs from the Myeloma XI trial

Authors: Croft, James, Ellis, Sidra, Sherborne, Amy L., Sharp, Kim, Price, Amy, Jenner, Matthew W., Drayson, Mark T., Owen, Roger G., Chown, Sally, Lindsay, Jindriska, Karunanithi, Kamaraj, Hunter, Hannah, Gregory, Walter M., Davies, Faith E., Morgan, Gareth J., Cook, Gordon, Atanesyan, Lilit, Savola, Suvi, Cairns, David A., Jackson, Graham, Houlston, Richard S., Kaiser, Martin F.

Source: Leukemia. 35(7):2043-2053

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193112090.0x000001&indx=1&recIds=ETOCvdc_100193112090.0x000001

Hallmarks of a genomically distinct subclass of head and neck cancer.

Authors: Muijlwijk, Tara, Nauta, Irene H., van der Lee, Anabel, Grünewald, Kari J. T., Brink, Arjen, Ganzevles, Sonja H., Baatenburg de Jong, Robert J., Atanesyan, Lilit, Savola, Suvi, van de Wiel, Mark A., Peferoen, Laura A. N., Bloemena, Elisabeth, van de Ven, Rieneke, Leemans, C. René, Poell, Jos B., Brakenhoff, Ruud H.

Source: Nature Communications; 10/20/2024, Vol. 14 Issue 1, p1-18, 18p

Subject Terms: SOMATIC mutation, REGULATORY T cells, HEAD & neck cancer, SQUAMOUS cell carcinoma, HUMAN papillomavirus

High-Throughput Molecular Cancer Cell Line Characterization Using Digital Multiplex Ligation-Dependent Probe Amplification for Improved Standardization of in Vitro Research

Authors: Menezes, Karen, Atanesyan, Lilit, Sherborne, Amy L., Steenkamer, Maryvonne, Clemens, Ivo, Savola, Suvi, Kaiser, Martin F.

Source: In The Journal of Molecular Diagnostics September 2020 22(9):1179-1188

Comprehensive profiling of disease-relevant copy number aberrations for advanced clinical diagnostics of pediatric acute lymphoblastic leukemia

Authors: Kiss, Richárd, Gángó, Ambrus, Benard-Slagter, Anne, Egyed, Bálint, Haltrich, Irén, Hegyi, Lajos, de Groot, Karel, Király, Péter Attila, Krizsán, Szilvia, Kajtár, Béla, Pikó, Henriett, Pajor, László, Vojcek, Ágnes, Matolcsy, András, Kovács, Gábor, Szuhai, Károly, Savola, Suvi, Bödör, Csaba, Alpár, Donát

Source: In Modern Pathology May 2020 33(5):812-824

Role of columnar cell lesions in breast carcinogenesis: analysis of chromosome 16 copy number changes by multiplex ligation-dependent probe amplification

Authors: de Boer, Mirthe, Verschuur-Maes, Anoek H.J., Buerger, Horst, Moelans, Cathy B, Steenkamer, Maryvonne, Savola, Suvi, van Diest, Paul J.

Source: In Modern Pathology December 2018 31(12):1816-1833

High-Throughput Copy Number Profiling by Digital Multiplex Ligation-Dependent Probe Amplification in Multiple Myeloma

Authors: Kosztolányi, Szabolcs, Kiss, Richárd, Atanesyan, Lilit, Gángó, Ambrus, de Groot, Karel, Steenkamer, Maryvonne, Jáksó, Pál, Matolcsy, András, Kajtár, Béla, Pajor, László, Szuhai, Károly, Savola, Suvi, Bödör, Csaba, Alpár, Donát

Source: In The Journal of Molecular Diagnostics November 2018 20(6):777-788

Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia

Authors: Benard-Slagter, Anne, Zondervan, Ilse, de Groot, Karel, Ghazavi, Farzaneh, Sarhadi, Virinder, Van Vlierberghe, Pieter, De Moerloose, Barbara, Schwab, Claire, Vettenranta, Kim, Harrison, Christine J., Knuutila, Sakari, Schouten, Jan, Lammens, Tim, Savola, Suvi

Source: In The Journal of Molecular Diagnostics September 2017 19(5):659-672

Validation of 34betaE12 immunoexpression in clear cell papillary renal cell carcinoma as a sensitive biomarker

Authors: Martignoni, Guido, Brunelli, Matteo, Segala, Diego, Munari, Enrico, Gobbo, Stefano, Cima, Luca, Borze, Ioana, Wirtanen, Tina, Sarhadi, Virinder Kaur, Atanesyan, Lilit, Savola, Suvi, Barzon, Luisa, Masi, Giulia, Fassan, Matteo, Eble, John N., Bohling, Tom, Cheng, Liang, Delahunt, Brett, Knuutila, Sakari

Source: In Pathology January 2017 49(1):10-18

Methylation-Specific Multiplex Ligation-Dependent Probe Amplification (MS-MLPA)

Authors: Moelans, Cathy B., Atanesyan, Lilit, Savola, Suvi P., van Diest, Paul J.

Source: Methods in molecular biology. 1708:537-550

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN614480899&indx=1&recIds=ETOCRN614480899

'Atypical' Pleomorphic Lipomatous Tumor

Authors: Creytens, David, Mentzel, Thomas, Ferdinande, Liesbeth, Lecoutere, Evelyne, van Gorp, Joost, Atanesyan, Lilit, de Groot, Karel, Savola, Suvi, Van Roy, Nadine, Van Dorpe, Jo, Flucke, Uta

Source: American journal of surgical pathology. 41(11):1443-1455

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100049653640.0x000001&indx=1&recIds=ETOCvdc_100049653640.0x000001

Renal cell carcinoma with smooth muscle stroma lacks chromosome 3p and VHL alterations

Authors: Martignoni, Guido, Brunelli, Matteo, Segala, Diego, Gobbo, Stefano, Borze, Ioana, Atanesyan, Lilit, Savola, Suvi, Barzon, Luisa, Masi, Giulia, Tardanico, Regina, Zhang, Shaobo, Eble, John N, Chilosi, Marco, Böhling, Tom, Cheng, Liang, Delahunt, Brett, Knuutila, Sakari

Source: In Modern Pathology May 2014 27(5):765-774

Targeted resequencing of 9p in acute lymphoblastic leukemia yields concordant results with array CGH and reveals novel genomic alterations

Authors: Sarhadi, Virinder Kaur, Lahti, Leo, Scheinin, Ilari, Tyybäkinoja, Anne, Savola, Suvi, Usvasalo, Anu, Räty, Riikka, Elonen, Erkki, Ellonen, Pekka, Saarinen-Pihkala, Ulla M., Knuutila, Sakari

Source: In Genomics September 2013 102(3):182-188

BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer

Authors: Lips, Esther H., Benard-Slagter, Anne, Opdam, Mark, Scheerman, Caroline E., Wesseling, Jelle, Hogervorst, Frans B. L., Linn, Sabine C., Savola, Suvi, Nederlof, Petra M.

Source: Breast cancer research. 22(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171990054.0x000001&indx=1&recIds=ETOCvdc_100171990054.0x000001

Homozygous deletions of cadherin genes in chondrosarcoma—an array comparative genomic hybridization study

Authors: Niini, Tarja, Scheinin, Ilari, Lahti, Leo, Savola, Suvi, Mertens, Fredrik, Hollmén, Jaakko, Böhling, Tom, Kivioja, Aarne, Nord, Karolin H., Knuutila, Sakari

Source: In Cancer Genetics November 2012 205(11):588-593

Routine application of a novel MLPA-based first-line screening test uncovers clinically relevant copy number aberrations in haematological malignancies undetectable by conventional cytogenetics

Authors: Konialis, Christopher, Savola, Suvi, Karapanou, Sophia, Markaki, Aggeliki, Karabela, Maria, Polychronopoulou, Sophia, Ampatzidou, Maria, Voulgarelis, Michael, Viniou, Nora-Athina, Variami, Eleni, Koumarianou, Argyro, Zoi, Katerina, Hagnefelt, Birgitta, Schouten, Jan P., Pangalos, Constantinos

Source: Hematology. 19(4):217-224

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108360907.0x000001&indx=1&recIds=ETOCvdc_100108360907.0x000001

Author Correction: Hallmarks of a genomically distinct subclass of head and neck cancer.

Authors: Muijlwijk, Tara, Nauta, Irene H., van der Lee, Anabel, Grünewald, Kari J. T., Brink, Arjen, Ganzevles, Sonja H., Baatenburg de Jong, Robert J., Atanesyan, Lilit, Savola, Suvi, van de Wiel, Mark A., Peferoen, Laura A. N., Bloemena, Elisabeth, van de Ven, Rieneke, Leemans, C. René, Poell, Jos B., Brakenhoff, Ruud H.

Source: Nature Communications; 2/17/2025, Vol. 16 Issue 1, p1-1, 1p

Subject Terms: HEAD & neck cancer, INTERNET publishing, PROGNOSIS, PARAGRAPHS

CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults—An array CGH study

Authors: Usvasalo, Anu, Savola, Suvi, Räty, Riikka, Vettenranta, Kim, Harila-Saari, Arja, Koistinen, Pirjo, Savolainen, Eeva-Riitta, Elonen, Erkki, Saarinen-Pihkala, Ulla M., Knuutila, Sakari

Source: In Leukemia Research 2008 32(8):1228-1235