Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis

Authors: Sünderhauf, Annika, Hicken, Maren, Schlichting, Heidi, Skibbe, Kerstin, Ragab, Mohab, Raschdorf, Annika, Hirose, Misa, Schäffler, Holger, Bokemeyer, Arne, Bettenworth, Dominik, Savitt, Anne G., Perner, Sven, Ibrahim, Saleh, Peerschke, Ellinor I., Ghebrehiwet, Berhane, Derer, Stefanie, Sina, Christian

Source: In Cellular and Molecular Gastroenterology and Hepatology 2021 12(1):229-250

The C1q Receptors: Focus on gC1qR/p33 (C1qBP, p32, HABP-1)1

Authors: Ghebrehiwet, Berhane ^*, Geisbrecht, Brian V., Xu, Xin, Savitt, Anne G., Peerschke, Ellinor I.B.

Source: In Seminars in Immunology October 2019 45

The C1q and gC1qR axis as a novel checkpoint inhibitor in cancer.

Authors: Ghebrehiwet, Berhane, Zaniewski, Michal, Fernandez, Audrey, DiGiovanni, Mathew, Reyes, Tiana N., Ping Ji, Savitt, Anne G., Williams, Jennie L., Seeliger, Markus A., Peerschke, Ellinor I. B.

Source: Frontiers in Immunology; 5/6/2024, p01-09, 9p

Subject Terms: CYTOTOXIC T cells, CYTOLOGY, CANCER cell proliferation, CANCER cells, IPILIMUMAB, ECULIZUMAB, T cells

Francisella tularensis Has a Significant Extracellular Phase in Infected Mice

Authors: Forestal, Colin A., Malik, Meenakshi, Catlett, Sally V., Savitt, Anne G., Benach, Jorge L., Sellati, Timothy J., Furie, Martha B.

Source: The Journal of Infectious Diseases, 2007 Jul 01. 196(1), 134-137.

Access URL: https://www.jstor.org/stable/30086976

Gene Expression Profiling in Conjunction with Physiological Rescues of IKKα-null Cells with Wild Type or Mutant IKKα Reveals Distinct Classes of IKKα/NF-κB-dependent Genes

Authors: Massa, Paul E. ^{‡, §, ¶}, Li, Xiang ^∥, Hanidu, Adedayo ^∥, Siamas, John ^§, Pariali, Milena ^¶, Pareja, Jessica ^**, Savitt, Anne G. ^**, Catron, Katrina M. ^∥, Li, Jun ^{∥, ‡‡}, Marcu, Kenneth B. ^{‡, §, ¶, **, §§}

Source: In Journal of Biological Chemistry 8 April 2005 280(14):14057-14069

Microbial Protein Binding to gC1qR Drives PLA2G1B-Induced CD4 T-Cell Anergy.

Authors: Pothlichet, Julien, Meola, Annalisa, Bugault, Florence, Jeammet, Louise, Savitt, Anne G., Ghebrehiwet, Berhane, Touqui, Lhousseine, Pouletty, Philippe, Fiore, Frédéric, Sauvanet, Alain, Thèze, Jacques

Source: Frontiers in Immunology; 3/22/2022, Vol. 13, p1-16, 16p

Subject Terms: CARRIER proteins, PROTEIN binding, CD4 antigen, STAPHYLOCOCCUS aureus infections, T cells, VIRAL envelope proteins

SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems.

Authors: Savitt, Anne G., Manimala, Samantha, White, Tiara, Fandaros, Marina, Yin, Wei, Duan, Huiquan, Xu, Xin, Geisbrecht, Brian V., Rubenstein, David A., Kaplan, Allen P., Peerschke, Ellinor I., Ghebrehiwet, Berhane

Source: Frontiers in Immunology; 11/5/2021, Vol. 12, p1-11, 11p

Subject Terms: COMPLEMENT activation, COVID-19, SARS-CoV-2, CYTOSKELETAL proteins, PATHOLOGICAL physiology, KALLIKREIN, KININS

New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells

Authors: Rowehl Rebecca A, Savitt Anne G, Zhu Shu, Wang Hichao, Wang Yuan, Das Manisha, Zuniga Edison S, Botchkina Galina I, Leyfman Yan, Ju Jingfang, Shroyer Kenneth, Ojima Iwao

Source: Molecular Cancer, Vol 9, Iss 1, p 192 (2010)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.molecular-cancer.com/content/9/1/192; https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/3a7c9613d4834ceea0367a1b3106e085

Extrusion of an imperfect palindrome to a cruciform in superhelical DNA: complete determination of energetics using a statistical mechanical model

Authors: Benham, Craig J, Savitt, Anne G, Bauer, William R ^*

Source: In Journal of Molecular Biology 2002 316(3):563-581

Low Glucose Mediated Fluconazole Tolerance in Cryptococcus neoformans.

Authors: Bhattacharya, Somanon, Oliveira, Natalia Kronbauer, Savitt, Anne G., Silva, Vanessa K. A., Krausert, Rachel B., Ghebrehiwet, Berhane, Fries, Bettina C.

Source: Journal of Fungi; Jun2021, Vol. 7 Issue 6, p1-19, 19p

Subject Terms: GLUCOSE, FLUCONAZOLE, CRYPTOCOCCUS neoformans, MITOCHONDRIA, ANEUPLOIDY

Fibers Generated by Plasma Des-AA Fibrin Monomers and Protofibril/Fibrinogen Clusters Bind Platelets: Clinical and Nonclinical Implications

Authors: Galanakis, Dennis K., Protopopova, Anna, Zhang, Liudi, Li, Kao, Marmorat, Clement, Scheiner, Tomas, Koo, Jaseung, Savitt, Anne G., Rafailovich, Miriam, Weisel, John

Source: TH Open; July 2021, Vol. 5 Issue: 3 pe273-e285, 13p

Anti gC1qR/p32/HABP1 Antibody Therapy Decreases Tumor Growth in an Orthotopic Murine Xenotransplant Model of Triple Negative Breast Cancer.

Authors: Peerschke, Ellinor I.¹, peersche@mskcc.org, Stanchina, Elisa de², destance@mskcc.org, Chang, Qing², changq@mskcc.org, Manova-Todorova, Katia², manovak@mskcc.org, Barlas, Afsar², barlasa@mskcc.org, Savitt, Anne G.³, anne.savitt@stonybrook.edu, Geisbrecht, Brian V.⁴, geisbrechtb@ksu.edu, Ghebrehiwet, Berhane⁵, Berhane.ghebrehiwet@stonybrookmedicine.edu

Source: Antibodies (2073-4468); Dec2020, Vol. 9 Issue 4, p51, 1p

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New-generation taxoid SB-T-1214 inhibits stemcell-related gene expression in 3D cancerspheroids induced by purified colontumor-initiating cells.

Authors: Botchkina, Galina I., Zuniga, Edison S., Das, Manisha, Yuan Wang, Hichao Wang, Shu Zhu, Savitt, Anne G., Rowehl, Rebecca A., Yan Leyfman, Jingfang Ju, Shroyer, Kenneth, Ojima, Iwao

Source: Molecular Cancer; 2010, Vol. 9, p192-203, 12p

Subject Terms: COLON cancer, STEM cells, CANCER cell growth regulation, CANCER treatment, CELLULAR pathology

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Francisella tularensisInfection-Derived Monoclonal Antibodies Provide Detection, Protection, and Therapy

Authors: Savitt, Anne G., Mena-Taboada, Patricio, Monsalve, Gloria, Benach, Jorge L.

Source: Clinical and Vaccine Immunology (formerly CDLI); March 2009, Vol. 16 Issue: 3 p414-422, 9p

LcrV Capture Enzyme-Linked Immunosorbent Assay for Detection of Yersinia pestisfrom Human Samples

Authors: Gomes-Solecki, Maria J. C., Savitt, Anne G., Rowehl, Rebecca, Glass, John D., Bliska, James B., Dattwyler, Raymond J.

Source: Clinical and Vaccine Immunology (formerly CDLI); February 2005, Vol. 12 Issue: 2 p339-346, 8p

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